Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
83716
Gene name Gene Name - the full gene name approved by the HGNC.
Cysteine rich secretory protein LCCL domain containing 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CRISPLD2
Synonyms (NCBI Gene) Gene synonyms aliases
CRISP11, LCRISP2, LGL1
Chromosome Chromosome number
16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
16q24.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT016863 hsa-miR-335-5p Microarray 18185580
MIRT719620 hsa-miR-300 HITS-CLIP 19536157
MIRT719619 hsa-miR-381-3p HITS-CLIP 19536157
MIRT719618 hsa-miR-6515-3p HITS-CLIP 19536157
MIRT719617 hsa-miR-642a-5p HITS-CLIP 19536157
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005539 Function Glycosaminoglycan binding IBA
GO:0005539 Function Glycosaminoglycan binding IEA
GO:0005576 Component Extracellular region IEA
GO:0005576 Component Extracellular region TAS
GO:0005615 Component Extracellular space IBA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
612434 25248 ENSG00000103196
Protein
UniProt ID Q9H0B8
Protein name Cysteine-rich secretory protein LCCL domain-containing 2 (Cysteine-rich secretory protein 11) (CRISP-11) (LCCL domain-containing cysteine-rich secretory protein 2)
Protein function Promotes matrix assembly.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00188 CAP 60 200 Cysteine-rich secretory protein family Domain
PF03815 LCCL 288 379 LCCL domain Domain
PF03815 LCCL 389 488 LCCL domain Domain
Sequence
Sequence length 497
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Neutrophil degranulation
<
Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Asthma Asthma (childhood onset) N/A N/A GWAS
Glioblastoma Glioblastoma N/A N/A GWAS
Pelvic Organ Prolapse Pelvic organ prolapse N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Asthma Associate 24926665, 31557467
Bone Diseases Associate 37021796
Cleft Lip Associate 20815724
Cleft Palate Associate 20815724, 27369588
Diabetes Mellitus Associate 40640313
Facial Pain Associate 21254358
Gaucher Disease Associate 30988500
Inflammation Associate 24926665
Neurodegenerative Diseases Inhibit 31219803
Orofacial Cleft 1 Associate 20815724