Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	83694
Gene name Gene Name - the full gene name approved by the HGNC.	Ribosomal protein S6 kinase like 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	RPS6KL1
Synonyms (NCBI Gene) Gene synonyms aliases	RSKL2
Chromosome Chromosome number	14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	14q24.3

Show/Hide all(216)

miRTarBase ID	miRNA	Experiments
MIRT1318906	hsa-miR-1185	CLIP-seq
MIRT1318907	hsa-miR-1200	CLIP-seq
MIRT1318908	hsa-miR-1208	CLIP-seq
MIRT1318909	hsa-miR-1224-3p	CLIP-seq
MIRT1318910	hsa-miR-1236	CLIP-seq
MIRT1318911	hsa-miR-1260	CLIP-seq
MIRT1318912	hsa-miR-1260b	CLIP-seq
MIRT1318913	hsa-miR-1273g	CLIP-seq
MIRT1318914	hsa-miR-1280	CLIP-seq
MIRT1318915	hsa-miR-1285	CLIP-seq
MIRT1318916	hsa-miR-1286	CLIP-seq
MIRT1318917	hsa-miR-1291	CLIP-seq
MIRT1318918	hsa-miR-1294	CLIP-seq
MIRT1318919	hsa-miR-1321	CLIP-seq
MIRT1318920	hsa-miR-1343	CLIP-seq
MIRT1318921	hsa-miR-140-3p	CLIP-seq
MIRT1318922	hsa-miR-146a	CLIP-seq
MIRT1318923	hsa-miR-146b-5p	CLIP-seq
MIRT1318924	hsa-miR-147	CLIP-seq
MIRT1318925	hsa-miR-149	CLIP-seq
MIRT1318926	hsa-miR-1827	CLIP-seq
MIRT1318927	hsa-miR-188-3p	CLIP-seq
MIRT1318928	hsa-miR-1915	CLIP-seq
MIRT1318929	hsa-miR-198	CLIP-seq
MIRT1318930	hsa-miR-2114	CLIP-seq
MIRT1318931	hsa-miR-218	CLIP-seq
MIRT1318932	hsa-miR-2355-5p	CLIP-seq
MIRT1318933	hsa-miR-28-5p	CLIP-seq
MIRT1318934	hsa-miR-2861	CLIP-seq
MIRT1318935	hsa-miR-3064-5p	CLIP-seq
MIRT1318936	hsa-miR-30a	CLIP-seq
MIRT1318937	hsa-miR-30b	CLIP-seq
MIRT1318938	hsa-miR-30c	CLIP-seq
MIRT1318939	hsa-miR-30d	CLIP-seq
MIRT1318940	hsa-miR-30e	CLIP-seq
MIRT1318941	hsa-miR-3120-5p	CLIP-seq
MIRT1318942	hsa-miR-3139	CLIP-seq
MIRT1318943	hsa-miR-3147	CLIP-seq
MIRT1318944	hsa-miR-3156-3p	CLIP-seq
MIRT1318945	hsa-miR-3162-5p	CLIP-seq
MIRT1318946	hsa-miR-3174	CLIP-seq
MIRT1318947	hsa-miR-3180-5p	CLIP-seq
MIRT1318948	hsa-miR-3187-5p	CLIP-seq
MIRT1318949	hsa-miR-323-3p	CLIP-seq
MIRT1318950	hsa-miR-328	CLIP-seq
MIRT1318951	hsa-miR-339-5p	CLIP-seq
MIRT1318952	hsa-miR-346	CLIP-seq
MIRT1318953	hsa-miR-34a	CLIP-seq
MIRT1318954	hsa-miR-34c-5p	CLIP-seq
MIRT1318955	hsa-miR-3545-5p	CLIP-seq
MIRT1318956	hsa-miR-3605-5p	CLIP-seq
MIRT1318957	hsa-miR-3619-3p	CLIP-seq
MIRT1318958	hsa-miR-3622a-5p	CLIP-seq
MIRT1318959	hsa-miR-3652	CLIP-seq
MIRT1318960	hsa-miR-3657	CLIP-seq
MIRT1318961	hsa-miR-3667-3p	CLIP-seq
MIRT1318962	hsa-miR-3679-5p	CLIP-seq
MIRT1318963	hsa-miR-378g	CLIP-seq
MIRT1318964	hsa-miR-3911	CLIP-seq
MIRT1318965	hsa-miR-3919	CLIP-seq
MIRT1318966	hsa-miR-3936	CLIP-seq
MIRT1318967	hsa-miR-3942-3p	CLIP-seq
MIRT1318968	hsa-miR-3977	CLIP-seq
MIRT1318969	hsa-miR-4251	CLIP-seq
MIRT1318970	hsa-miR-4259	CLIP-seq
MIRT1318971	hsa-miR-4265	CLIP-seq
MIRT1318972	hsa-miR-4266	CLIP-seq
MIRT1318973	hsa-miR-4267	CLIP-seq
MIRT1318974	hsa-miR-4269	CLIP-seq
MIRT1318975	hsa-miR-4270	CLIP-seq
MIRT1318976	hsa-miR-4276	CLIP-seq
MIRT1318977	hsa-miR-4288	CLIP-seq
MIRT1318978	hsa-miR-4293	CLIP-seq
MIRT1318979	hsa-miR-4296	CLIP-seq
MIRT1318980	hsa-miR-4313	CLIP-seq
MIRT1318981	hsa-miR-4314	CLIP-seq
MIRT1318982	hsa-miR-4316	CLIP-seq
MIRT1318983	hsa-miR-4322	CLIP-seq
MIRT1318984	hsa-miR-4324	CLIP-seq
MIRT1318985	hsa-miR-433	CLIP-seq
MIRT1318986	hsa-miR-4417	CLIP-seq
MIRT1318987	hsa-miR-4421	CLIP-seq
MIRT1318988	hsa-miR-4430	CLIP-seq
MIRT1318989	hsa-miR-4436a	CLIP-seq
MIRT1318990	hsa-miR-4441	CLIP-seq
MIRT1318991	hsa-miR-4469	CLIP-seq
MIRT1318992	hsa-miR-4486	CLIP-seq
MIRT1318993	hsa-miR-4487	CLIP-seq
MIRT1318994	hsa-miR-449a	CLIP-seq
MIRT1318995	hsa-miR-449b	CLIP-seq
MIRT1318996	hsa-miR-4505	CLIP-seq
MIRT1318997	hsa-miR-4645-5p	CLIP-seq
MIRT1318998	hsa-miR-4669	CLIP-seq
MIRT1318999	hsa-miR-4673	CLIP-seq
MIRT1319000	hsa-miR-4676-5p	CLIP-seq
MIRT1319001	hsa-miR-4677-3p	CLIP-seq
MIRT1319002	hsa-miR-4683	CLIP-seq
MIRT1319003	hsa-miR-4685-5p	CLIP-seq
MIRT1319004	hsa-miR-4738-3p	CLIP-seq
MIRT1319005	hsa-miR-4739	CLIP-seq
MIRT1319006	hsa-miR-4755-3p	CLIP-seq
MIRT1319007	hsa-miR-4756-3p	CLIP-seq
MIRT1319008	hsa-miR-4756-5p	CLIP-seq
MIRT1319009	hsa-miR-4759	CLIP-seq
MIRT1319010	hsa-miR-4776-5p	CLIP-seq
MIRT1319011	hsa-miR-4786-5p	CLIP-seq
MIRT1319012	hsa-miR-4794	CLIP-seq
MIRT1319013	hsa-miR-4795-5p	CLIP-seq
MIRT1319014	hsa-miR-4800-5p	CLIP-seq
MIRT1319015	hsa-miR-511	CLIP-seq
MIRT1319016	hsa-miR-520a-5p	CLIP-seq
MIRT1319017	hsa-miR-525-5p	CLIP-seq
MIRT1319018	hsa-miR-544b	CLIP-seq
MIRT1319019	hsa-miR-575	CLIP-seq
MIRT1319020	hsa-miR-582-3p	CLIP-seq
MIRT1319021	hsa-miR-589	CLIP-seq
MIRT1319022	hsa-miR-612	CLIP-seq
MIRT1319023	hsa-miR-622	CLIP-seq
MIRT1319024	hsa-miR-632	CLIP-seq
MIRT1319025	hsa-miR-636	CLIP-seq
MIRT1319026	hsa-miR-642a	CLIP-seq
MIRT1319027	hsa-miR-644	CLIP-seq
MIRT1319028	hsa-miR-665	CLIP-seq
MIRT1319029	hsa-miR-708	CLIP-seq
MIRT1319030	hsa-miR-766	CLIP-seq
MIRT1319031	hsa-miR-876-3p	CLIP-seq
MIRT1319032	hsa-miR-940	CLIP-seq
MIRT1318965	hsa-miR-3919	CLIP-seq
MIRT1318967	hsa-miR-3942-3p	CLIP-seq
MIRT1319007	hsa-miR-4756-3p	CLIP-seq
MIRT2094829	hsa-miR-1254	CLIP-seq
MIRT2094830	hsa-miR-129-3p	CLIP-seq
MIRT2094831	hsa-miR-134	CLIP-seq
MIRT2094832	hsa-miR-214	CLIP-seq
MIRT2094833	hsa-miR-219-2-3p	CLIP-seq
MIRT1318932	hsa-miR-2355-5p	CLIP-seq
MIRT2094834	hsa-miR-2964a-3p	CLIP-seq
MIRT2094835	hsa-miR-302f	CLIP-seq
MIRT2094836	hsa-miR-3116	CLIP-seq
MIRT2094837	hsa-miR-3118	CLIP-seq
MIRT2094838	hsa-miR-3136-5p	CLIP-seq
MIRT2094839	hsa-miR-3170	CLIP-seq
MIRT1318946	hsa-miR-3174	CLIP-seq
MIRT2094840	hsa-miR-323-5p	CLIP-seq
MIRT1318953	hsa-miR-34a	CLIP-seq
MIRT1318954	hsa-miR-34c-5p	CLIP-seq
MIRT2094841	hsa-miR-3611	CLIP-seq
MIRT2094842	hsa-miR-3619-5p	CLIP-seq
MIRT2094843	hsa-miR-3665	CLIP-seq
MIRT1318965	hsa-miR-3919	CLIP-seq
MIRT2094844	hsa-miR-421	CLIP-seq
MIRT2094845	hsa-miR-4260	CLIP-seq
MIRT1318984	hsa-miR-4324	CLIP-seq
MIRT2094846	hsa-miR-4438	CLIP-seq
MIRT2094847	hsa-miR-4439	CLIP-seq
MIRT1318993	hsa-miR-4487	CLIP-seq
MIRT1318994	hsa-miR-449a	CLIP-seq
MIRT1318995	hsa-miR-449b	CLIP-seq
MIRT2094848	hsa-miR-4530	CLIP-seq
MIRT2094849	hsa-miR-4680-3p	CLIP-seq
MIRT2094850	hsa-miR-4690-5p	CLIP-seq
MIRT2094851	hsa-miR-4709-5p	CLIP-seq
MIRT1319007	hsa-miR-4756-3p	CLIP-seq
MIRT2094852	hsa-miR-4786-3p	CLIP-seq
MIRT2094853	hsa-miR-486-3p	CLIP-seq
MIRT2094854	hsa-miR-505	CLIP-seq
MIRT2094855	hsa-miR-5095	CLIP-seq
MIRT2094856	hsa-miR-615-5p	CLIP-seq
MIRT2094857	hsa-miR-671-5p	CLIP-seq
MIRT2094858	hsa-miR-758	CLIP-seq
MIRT2094859	hsa-miR-761	CLIP-seq
MIRT1319030	hsa-miR-766	CLIP-seq
MIRT2319227	hsa-miR-1207-5p	CLIP-seq
MIRT2319228	hsa-miR-1267	CLIP-seq
MIRT2319229	hsa-miR-128	CLIP-seq
MIRT2319230	hsa-miR-129-5p	CLIP-seq
MIRT2319231	hsa-miR-133a	CLIP-seq
MIRT2319232	hsa-miR-133b	CLIP-seq
MIRT2094831	hsa-miR-134	CLIP-seq
MIRT2319233	hsa-miR-140-5p	CLIP-seq
MIRT2319234	hsa-miR-185	CLIP-seq
MIRT2319235	hsa-miR-2682	CLIP-seq
MIRT2319236	hsa-miR-27a	CLIP-seq
MIRT2319237	hsa-miR-27b	CLIP-seq
MIRT2094837	hsa-miR-3118	CLIP-seq
MIRT2319238	hsa-miR-3132	CLIP-seq
MIRT2094838	hsa-miR-3136-5p	CLIP-seq
MIRT2319239	hsa-miR-3164	CLIP-seq
MIRT2319240	hsa-miR-4286	CLIP-seq
MIRT2319241	hsa-miR-4306	CLIP-seq
MIRT2319242	hsa-miR-4307	CLIP-seq
MIRT1318984	hsa-miR-4324	CLIP-seq
MIRT1318989	hsa-miR-4436a	CLIP-seq
MIRT2094847	hsa-miR-4439	CLIP-seq
MIRT2319243	hsa-miR-449c	CLIP-seq
MIRT2319244	hsa-miR-4513	CLIP-seq
MIRT2319245	hsa-miR-4644	CLIP-seq
MIRT1319000	hsa-miR-4676-5p	CLIP-seq
MIRT2319246	hsa-miR-4679	CLIP-seq
MIRT2319247	hsa-miR-4736	CLIP-seq
MIRT2319248	hsa-miR-4763-3p	CLIP-seq
MIRT1319015	hsa-miR-511	CLIP-seq
MIRT2319249	hsa-miR-516b	CLIP-seq
MIRT1319019	hsa-miR-575	CLIP-seq
MIRT1319023	hsa-miR-622	CLIP-seq
MIRT2319250	hsa-miR-720	CLIP-seq
MIRT1319032	hsa-miR-940	CLIP-seq
MIRT2319251	hsa-miR-943	CLIP-seq
MIRT2094839	hsa-miR-3170	CLIP-seq
MIRT2094845	hsa-miR-4260	CLIP-seq
MIRT2094856	hsa-miR-615-5p	CLIP-seq
MIRT2094839	hsa-miR-3170	CLIP-seq
MIRT2094841	hsa-miR-3611	CLIP-seq
MIRT2094845	hsa-miR-4260	CLIP-seq
MIRT2094856	hsa-miR-615-5p	CLIP-seq
MIRT2094858	hsa-miR-758	CLIP-seq

Show/Hide all(10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0005515	Function	Protein binding	IPI	33961781
GO:0005524	Function	ATP binding	IEA
GO:0005840	Component	Ribosome	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0106310	Function	Protein serine kinase activity	IEA
GO:1990904	Component	Ribonucleoprotein complex	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Protein

UniProt ID

Q9Y6S9

Protein name

Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04212	MIT	50 → 115	MIT (microtubule interacting and transport) domain	Domain
PF00069	Pkinase	375 → 539	Protein kinase domain	Domain

Sequence

MSLVACECLPSPGLEPEPCSRARSQAHVYLEQIRNRVALGVPDMTKRDYLVDAATQIRLA
LERDVSEDYEAAFNHYQNGVDVLLRGIHVDPNKERREAVKLKITKYLRRAEEIFNCHLQR
PLSSGASPSAGFSSLRLRPIRTLSSAVEQLRGCRVVGVIEKVQLVQDPATGGTFVVKSLP
RCHMVSRERLTIIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHLLSQAHSRHSGL
SSGSTQERMKAQLNPHLNLLTPARLPSGHAPGQDRIALEPPRTSPNLLLAGEAPSTRPQR
EAEGEPTARTSTSGSSDLPKAPGGHLHLQARRAGQNSDAGPPRGLTWVPEGAGPVLGGCG
RGMDQSCLSADGAGRGCGRATWSVREEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLL
DQAGHIRLTYFGQWSEVEPQCCGEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTG
MALSQSHPSGIQAHTQLQLPEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFS
TIQWSKLVG

Sequence length

549

Interactions

View interactions

Show/Hide Unknown Diseases (2)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Neuroticism	Neuroticism	N/A	N/A	GWAS
Prostate cancer	Prostate cancer	N/A	N/A	GWAS

Show/Hide Text Mining Associations (1)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Carcinoma Non Small Cell Lung	Associate	31886214

RPS6KL1 (ribosomal protein S6 kinase like 1)