TLN2 (talin 2)

Gene

• Entrez ID: 83660
• Gene name: Talin 2
• Gene symbol: TLN2
• Synonyms (NCBI Gene): ILWEQ
• Chromosome: 15
• Chromosome location: 15q22.2
• Summary: This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a differe

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT006999	hsa-miR-194-5p	MDA-MB-361 and MDA-MB-231"	22829924
MIRT007253	hsa-miR-132-3p	Luciferase reporter assay	22310291
MIRT007253	hsa-miR-132-3p	Luciferase reporter assay	22310291
MIRT007253	hsa-miR-132-3p	Luciferase reporter assay	22330136
MIRT498536	hsa-miR-6758-5p	PAR-CLIP	24398324
MIRT498535	hsa-miR-6856-5p	PAR-CLIP	24398324
MIRT498533	hsa-miR-6087	PAR-CLIP	24398324
MIRT498534	hsa-miR-6804-5p	PAR-CLIP	24398324
MIRT498532	hsa-miR-658	PAR-CLIP	24398324
MIRT498531	hsa-miR-25-5p	PAR-CLIP	24398324
MIRT498225	hsa-miR-4328	PAR-CLIP	22291592
MIRT498224	hsa-miR-1285-3p	PAR-CLIP	22291592
MIRT498223	hsa-miR-3187-5p	PAR-CLIP	22291592
MIRT498222	hsa-miR-5189-5p	PAR-CLIP	22291592
MIRT498221	hsa-miR-612	PAR-CLIP	22291592
MIRT498220	hsa-miR-6860	PAR-CLIP	22291592
MIRT498219	hsa-miR-4486	PAR-CLIP	22291592
MIRT498218	hsa-miR-378g	PAR-CLIP	22291592
MIRT498217	hsa-miR-4640-5p	PAR-CLIP	22291592
MIRT498216	hsa-miR-4726-5p	PAR-CLIP	22291592
MIRT498215	hsa-miR-6508-3p	PAR-CLIP	22291592
MIRT498214	hsa-miR-4314	PAR-CLIP	22291592
MIRT498536	hsa-miR-6758-5p	PAR-CLIP	24398324
MIRT498535	hsa-miR-6856-5p	PAR-CLIP	24398324
MIRT498533	hsa-miR-6087	PAR-CLIP	24398324
MIRT498534	hsa-miR-6804-5p	PAR-CLIP	24398324
MIRT498532	hsa-miR-658	PAR-CLIP	24398324
MIRT498531	hsa-miR-25-5p	PAR-CLIP	24398324
MIRT498225	hsa-miR-4328	PAR-CLIP	22291592
MIRT498224	hsa-miR-1285-3p	PAR-CLIP	22291592
MIRT498223	hsa-miR-3187-5p	PAR-CLIP	22291592
MIRT498222	hsa-miR-5189-5p	PAR-CLIP	22291592
MIRT498221	hsa-miR-612	PAR-CLIP	22291592
MIRT498220	hsa-miR-6860	PAR-CLIP	22291592
MIRT498219	hsa-miR-4486	PAR-CLIP	22291592
MIRT498218	hsa-miR-378g	PAR-CLIP	22291592
MIRT498217	hsa-miR-4640-5p	PAR-CLIP	22291592
MIRT498216	hsa-miR-4726-5p	PAR-CLIP	22291592
MIRT498215	hsa-miR-6508-3p	PAR-CLIP	22291592
MIRT498214	hsa-miR-4314	PAR-CLIP	22291592
MIRT1426771	hsa-miR-1200	CLIP-seq
MIRT1426772	hsa-miR-1262	CLIP-seq
MIRT1426773	hsa-miR-1264	CLIP-seq
MIRT1426774	hsa-miR-1269	CLIP-seq
MIRT1426775	hsa-miR-1269b	CLIP-seq
MIRT1426776	hsa-miR-1299	CLIP-seq
MIRT1426777	hsa-miR-132	CLIP-seq
MIRT1426778	hsa-miR-1825	CLIP-seq
MIRT1426779	hsa-miR-1827	CLIP-seq
MIRT1426780	hsa-miR-186	CLIP-seq
MIRT1426781	hsa-miR-1913	CLIP-seq
MIRT1426782	hsa-miR-194	CLIP-seq
MIRT1426783	hsa-miR-1976	CLIP-seq
MIRT1426784	hsa-miR-2053	CLIP-seq
MIRT1426785	hsa-miR-208a	CLIP-seq
MIRT1426786	hsa-miR-208b	CLIP-seq
MIRT1426787	hsa-miR-212	CLIP-seq
MIRT1426788	hsa-miR-2355-5p	CLIP-seq
MIRT1426789	hsa-miR-23a	CLIP-seq
MIRT1426790	hsa-miR-23b	CLIP-seq
MIRT1426791	hsa-miR-23c	CLIP-seq
MIRT1426792	hsa-miR-2467-3p	CLIP-seq
MIRT1426793	hsa-miR-297	CLIP-seq
MIRT1426794	hsa-miR-3065-5p	CLIP-seq
MIRT1426795	hsa-miR-3153	CLIP-seq
MIRT1426796	hsa-miR-3166	CLIP-seq
MIRT1426797	hsa-miR-3183	CLIP-seq
MIRT1426798	hsa-miR-3192	CLIP-seq
MIRT1426799	hsa-miR-324-3p	CLIP-seq
MIRT1426800	hsa-miR-331-3p	CLIP-seq
MIRT1426801	hsa-miR-338-3p	CLIP-seq
MIRT1426802	hsa-miR-3609	CLIP-seq
MIRT1426803	hsa-miR-3617	CLIP-seq
MIRT1426804	hsa-miR-3620	CLIP-seq
MIRT1426805	hsa-miR-3660	CLIP-seq
MIRT1426806	hsa-miR-3664-5p	CLIP-seq
MIRT1426807	hsa-miR-3689a-3p	CLIP-seq
MIRT1426808	hsa-miR-3689c	CLIP-seq
MIRT1426809	hsa-miR-3689d	CLIP-seq
MIRT1426810	hsa-miR-3690	CLIP-seq
MIRT1426811	hsa-miR-3913-3p	CLIP-seq
MIRT1426812	hsa-miR-3928	CLIP-seq
MIRT1426813	hsa-miR-3940-5p	CLIP-seq
MIRT1426814	hsa-miR-4254	CLIP-seq
MIRT1426815	hsa-miR-4286	CLIP-seq
MIRT1426816	hsa-miR-4292	CLIP-seq
MIRT1426817	hsa-miR-4297	CLIP-seq
MIRT1426818	hsa-miR-4308	CLIP-seq
MIRT1426819	hsa-miR-4316	CLIP-seq
MIRT1426820	hsa-miR-4324	CLIP-seq
MIRT1426821	hsa-miR-4329	CLIP-seq
MIRT1426822	hsa-miR-4443	CLIP-seq
MIRT1426823	hsa-miR-4446-3p	CLIP-seq
MIRT1426824	hsa-miR-4462	CLIP-seq
MIRT1426825	hsa-miR-4477a	CLIP-seq
MIRT1426826	hsa-miR-4484	CLIP-seq
MIRT1426827	hsa-miR-4492	CLIP-seq
MIRT1426828	hsa-miR-4498	CLIP-seq
MIRT1426829	hsa-miR-4501	CLIP-seq
MIRT1426830	hsa-miR-4504	CLIP-seq
MIRT1426831	hsa-miR-4505	CLIP-seq
MIRT1426832	hsa-miR-4507	CLIP-seq
MIRT1426833	hsa-miR-4520b-3p	CLIP-seq
MIRT1426834	hsa-miR-4526	CLIP-seq
MIRT1426835	hsa-miR-4529-3p	CLIP-seq
MIRT1426836	hsa-miR-4530	CLIP-seq
MIRT1426837	hsa-miR-455-3p	CLIP-seq
MIRT1426838	hsa-miR-4639-3p	CLIP-seq
MIRT1426839	hsa-miR-4640-3p	CLIP-seq
MIRT1426840	hsa-miR-4642	CLIP-seq
MIRT1426841	hsa-miR-4668-5p	CLIP-seq
MIRT1426842	hsa-miR-4676-5p	CLIP-seq
MIRT1426843	hsa-miR-4701-3p	CLIP-seq
MIRT1426844	hsa-miR-4708-5p	CLIP-seq
MIRT1426845	hsa-miR-4709-3p	CLIP-seq
MIRT1426846	hsa-miR-4710	CLIP-seq
MIRT1426847	hsa-miR-4714-5p	CLIP-seq
MIRT1426848	hsa-miR-4721	CLIP-seq
MIRT1426849	hsa-miR-4723-3p	CLIP-seq
MIRT1426850	hsa-miR-4728-5p	CLIP-seq
MIRT1426851	hsa-miR-4771	CLIP-seq
MIRT1426852	hsa-miR-4782-5p	CLIP-seq
MIRT1426853	hsa-miR-4786-5p	CLIP-seq
MIRT1426854	hsa-miR-4792	CLIP-seq
MIRT1426855	hsa-miR-489	CLIP-seq
MIRT1426856	hsa-miR-499-5p	CLIP-seq
MIRT1426857	hsa-miR-513a-3p	CLIP-seq
MIRT1426858	hsa-miR-516b	CLIP-seq
MIRT1426859	hsa-miR-520g	CLIP-seq
MIRT1426860	hsa-miR-520h	CLIP-seq
MIRT1426861	hsa-miR-532-5p	CLIP-seq
MIRT1426862	hsa-miR-542-3p	CLIP-seq
MIRT1426863	hsa-miR-544b	CLIP-seq
MIRT1426864	hsa-miR-548ah	CLIP-seq
MIRT1426865	hsa-miR-548m	CLIP-seq
MIRT1426866	hsa-miR-567	CLIP-seq
MIRT1426867	hsa-miR-575	CLIP-seq
MIRT1426868	hsa-miR-578	CLIP-seq
MIRT1426869	hsa-miR-595	CLIP-seq
MIRT1426870	hsa-miR-635	CLIP-seq
MIRT1426871	hsa-miR-641	CLIP-seq
MIRT1426872	hsa-miR-762	CLIP-seq
MIRT1426873	hsa-miR-769-5p	CLIP-seq
MIRT1426874	hsa-miR-875-3p	CLIP-seq
MIRT1426875	hsa-miR-922	CLIP-seq
MIRT1426876	hsa-miR-938	CLIP-seq
MIRT2127845	hsa-miR-1184	CLIP-seq
MIRT1426771	hsa-miR-1200	CLIP-seq
MIRT2127846	hsa-miR-1205	CLIP-seq
MIRT2127847	hsa-miR-1265	CLIP-seq
MIRT2127848	hsa-miR-1285	CLIP-seq
MIRT1426776	hsa-miR-1299	CLIP-seq
MIRT1426777	hsa-miR-132	CLIP-seq
MIRT2127849	hsa-miR-1909	CLIP-seq
MIRT1426782	hsa-miR-194	CLIP-seq
MIRT1426787	hsa-miR-212	CLIP-seq
MIRT2127850	hsa-miR-2392	CLIP-seq
MIRT2127851	hsa-miR-3064-5p	CLIP-seq
MIRT2127852	hsa-miR-3158-5p	CLIP-seq
MIRT2127853	hsa-miR-3170	CLIP-seq
MIRT2127854	hsa-miR-3173-3p	CLIP-seq
MIRT2127855	hsa-miR-3613-5p	CLIP-seq
MIRT1426813	hsa-miR-3940-5p	CLIP-seq
MIRT1426816	hsa-miR-4292	CLIP-seq
MIRT1426818	hsa-miR-4308	CLIP-seq
MIRT1426820	hsa-miR-4324	CLIP-seq
MIRT2127856	hsa-miR-4428	CLIP-seq
MIRT1426831	hsa-miR-4505	CLIP-seq
MIRT1426832	hsa-miR-4507	CLIP-seq
MIRT2127857	hsa-miR-4522	CLIP-seq
MIRT1426837	hsa-miR-455-3p	CLIP-seq
MIRT1426838	hsa-miR-4639-3p	CLIP-seq
MIRT1426847	hsa-miR-4714-5p	CLIP-seq
MIRT1426863	hsa-miR-544b	CLIP-seq
MIRT2127858	hsa-miR-555	CLIP-seq
MIRT2127859	hsa-miR-586	CLIP-seq
MIRT2127860	hsa-miR-624	CLIP-seq
MIRT2127861	hsa-miR-651	CLIP-seq
MIRT1426874	hsa-miR-875-3p	CLIP-seq
MIRT1426771	hsa-miR-1200	CLIP-seq
MIRT1426772	hsa-miR-1262	CLIP-seq
MIRT1426773	hsa-miR-1264	CLIP-seq
MIRT2127848	hsa-miR-1285	CLIP-seq
MIRT2349524	hsa-miR-146b-3p	CLIP-seq
MIRT1426778	hsa-miR-1825	CLIP-seq
MIRT2349525	hsa-miR-24	CLIP-seq
MIRT1426792	hsa-miR-2467-3p	CLIP-seq
MIRT2349526	hsa-miR-2467-5p	CLIP-seq
MIRT2349527	hsa-miR-3125	CLIP-seq
MIRT2349528	hsa-miR-3130-3p	CLIP-seq
MIRT2349529	hsa-miR-3173-5p	CLIP-seq
MIRT2349530	hsa-miR-326	CLIP-seq
MIRT2349531	hsa-miR-330-5p	CLIP-seq
MIRT1426800	hsa-miR-331-3p	CLIP-seq
MIRT2349532	hsa-miR-3612	CLIP-seq
MIRT1426803	hsa-miR-3617	CLIP-seq
MIRT1426805	hsa-miR-3660	CLIP-seq
MIRT1426806	hsa-miR-3664-5p	CLIP-seq
MIRT2349533	hsa-miR-371-3p	CLIP-seq
MIRT2349534	hsa-miR-3916	CLIP-seq
MIRT1426813	hsa-miR-3940-5p	CLIP-seq
MIRT1426816	hsa-miR-4292	CLIP-seq
MIRT1426820	hsa-miR-4324	CLIP-seq
MIRT2349535	hsa-miR-4330	CLIP-seq
MIRT2349536	hsa-miR-4426	CLIP-seq
MIRT2349537	hsa-miR-4436b-3p	CLIP-seq
MIRT2349538	hsa-miR-4459	CLIP-seq
MIRT1426832	hsa-miR-4507	CLIP-seq
MIRT1426834	hsa-miR-4526	CLIP-seq
MIRT1426838	hsa-miR-4639-3p	CLIP-seq
MIRT1426839	hsa-miR-4640-3p	CLIP-seq
MIRT2349539	hsa-miR-4647	CLIP-seq
MIRT2349540	hsa-miR-466	CLIP-seq
MIRT2349541	hsa-miR-4662b	CLIP-seq
MIRT1426842	hsa-miR-4676-5p	CLIP-seq
MIRT2349542	hsa-miR-4695-5p	CLIP-seq
MIRT2349543	hsa-miR-4700-3p	CLIP-seq
MIRT1426843	hsa-miR-4701-3p	CLIP-seq
MIRT1426847	hsa-miR-4714-5p	CLIP-seq
MIRT2349544	hsa-miR-4766-5p	CLIP-seq
MIRT1426854	hsa-miR-4792	CLIP-seq
MIRT2349545	hsa-miR-4793-3p	CLIP-seq
MIRT2349546	hsa-miR-4802-3p	CLIP-seq
MIRT2349547	hsa-miR-5095	CLIP-seq
MIRT2349548	hsa-miR-5096	CLIP-seq
MIRT1426863	hsa-miR-544b	CLIP-seq
MIRT1426867	hsa-miR-575	CLIP-seq
MIRT2349549	hsa-miR-603	CLIP-seq
MIRT1426871	hsa-miR-641	CLIP-seq
MIRT2349550	hsa-miR-650	CLIP-seq
MIRT2349551	hsa-miR-874	CLIP-seq
MIRT2395849	hsa-miR-1	CLIP-seq
MIRT1426776	hsa-miR-1299	CLIP-seq
MIRT2395850	hsa-miR-206	CLIP-seq
MIRT2395851	hsa-miR-3184	CLIP-seq
MIRT1426811	hsa-miR-3913-3p	CLIP-seq
MIRT1426812	hsa-miR-3928	CLIP-seq
MIRT2395852	hsa-miR-423-5p	CLIP-seq
MIRT2395853	hsa-miR-4293	CLIP-seq
MIRT2349538	hsa-miR-4459	CLIP-seq
MIRT1426830	hsa-miR-4504	CLIP-seq
MIRT2349542	hsa-miR-4695-5p	CLIP-seq
MIRT2349543	hsa-miR-4700-3p	CLIP-seq
MIRT1426852	hsa-miR-4782-5p	CLIP-seq
MIRT1426855	hsa-miR-489	CLIP-seq
MIRT2349547	hsa-miR-5095	CLIP-seq
MIRT1426858	hsa-miR-516b	CLIP-seq
MIRT1426862	hsa-miR-542-3p	CLIP-seq
MIRT1426863	hsa-miR-544b	CLIP-seq
MIRT1426869	hsa-miR-595	CLIP-seq
MIRT2395854	hsa-miR-596	CLIP-seq
MIRT2395855	hsa-miR-613	CLIP-seq
MIRT1426874	hsa-miR-875-3p	CLIP-seq
MIRT2461504	hsa-miR-1276	CLIP-seq
MIRT2461505	hsa-miR-4311	CLIP-seq
MIRT2461506	hsa-miR-4690-5p	CLIP-seq
MIRT2461507	hsa-miR-487a	CLIP-seq
MIRT2461508	hsa-miR-583	CLIP-seq
MIRT2461509	hsa-miR-665	CLIP-seq
MIRT2643000	hsa-miR-1178	CLIP-seq
MIRT2127845	hsa-miR-1184	CLIP-seq
MIRT1426771	hsa-miR-1200	CLIP-seq
MIRT2127846	hsa-miR-1205	CLIP-seq
MIRT2643001	hsa-miR-1255a	CLIP-seq
MIRT2643002	hsa-miR-1255b	CLIP-seq
MIRT1426772	hsa-miR-1262	CLIP-seq
MIRT1426774	hsa-miR-1269	CLIP-seq
MIRT1426775	hsa-miR-1269b	CLIP-seq
MIRT1426777	hsa-miR-132	CLIP-seq
MIRT2643003	hsa-miR-146a	CLIP-seq
MIRT2643004	hsa-miR-146b-5p	CLIP-seq
MIRT2643005	hsa-miR-147	CLIP-seq
MIRT1426779	hsa-miR-1827	CLIP-seq
MIRT2127849	hsa-miR-1909	CLIP-seq
MIRT1426781	hsa-miR-1913	CLIP-seq
MIRT2643006	hsa-miR-193a-5p	CLIP-seq
MIRT1426782	hsa-miR-194	CLIP-seq
MIRT1426783	hsa-miR-1976	CLIP-seq
MIRT2643007	hsa-miR-19a	CLIP-seq
MIRT2643008	hsa-miR-19b	CLIP-seq
MIRT2643009	hsa-miR-200b	CLIP-seq
MIRT2643010	hsa-miR-200c	CLIP-seq
MIRT1426787	hsa-miR-212	CLIP-seq
MIRT2349525	hsa-miR-24	CLIP-seq
MIRT1426792	hsa-miR-2467-3p	CLIP-seq
MIRT2643011	hsa-miR-31	CLIP-seq
MIRT2127852	hsa-miR-3158-5p	CLIP-seq
MIRT2643012	hsa-miR-3160-3p	CLIP-seq
MIRT2127854	hsa-miR-3173-3p	CLIP-seq
MIRT2643013	hsa-miR-3180	CLIP-seq
MIRT2643014	hsa-miR-3180-3p	CLIP-seq
MIRT1426797	hsa-miR-3183	CLIP-seq
MIRT2395851	hsa-miR-3184	CLIP-seq
MIRT1426798	hsa-miR-3192	CLIP-seq
MIRT2643015	hsa-miR-3196	CLIP-seq
MIRT1426799	hsa-miR-324-3p	CLIP-seq
MIRT2643016	hsa-miR-329	CLIP-seq
MIRT1426800	hsa-miR-331-3p	CLIP-seq
MIRT2349532	hsa-miR-3612	CLIP-seq
MIRT2127855	hsa-miR-3613-5p	CLIP-seq
MIRT2643017	hsa-miR-362-3p	CLIP-seq
MIRT1426806	hsa-miR-3664-5p	CLIP-seq
MIRT2643018	hsa-miR-3691-5p	CLIP-seq
MIRT2643019	hsa-miR-369-3p	CLIP-seq
MIRT2643020	hsa-miR-3911	CLIP-seq
MIRT1426812	hsa-miR-3928	CLIP-seq
MIRT1426813	hsa-miR-3940-5p	CLIP-seq
MIRT2643021	hsa-miR-3941	CLIP-seq
MIRT2395852	hsa-miR-423-5p	CLIP-seq
MIRT2643022	hsa-miR-4265	CLIP-seq
MIRT2643023	hsa-miR-429	CLIP-seq
MIRT1426816	hsa-miR-4292	CLIP-seq
MIRT2643024	hsa-miR-4296	CLIP-seq
MIRT1426817	hsa-miR-4297	CLIP-seq
MIRT2643025	hsa-miR-4300	CLIP-seq
MIRT1426819	hsa-miR-4316	CLIP-seq
MIRT2643026	hsa-miR-4322	CLIP-seq
MIRT1426820	hsa-miR-4324	CLIP-seq
MIRT1426821	hsa-miR-4329	CLIP-seq
MIRT2349536	hsa-miR-4426	CLIP-seq
MIRT2127856	hsa-miR-4428	CLIP-seq
MIRT1426824	hsa-miR-4462	CLIP-seq
MIRT2643027	hsa-miR-4487	CLIP-seq
MIRT2643028	hsa-miR-4494	CLIP-seq
MIRT1426832	hsa-miR-4507	CLIP-seq
MIRT1426833	hsa-miR-4520b-3p	CLIP-seq
MIRT2127857	hsa-miR-4522	CLIP-seq
MIRT1426835	hsa-miR-4529-3p	CLIP-seq
MIRT1426837	hsa-miR-455-3p	CLIP-seq
MIRT1426839	hsa-miR-4640-3p	CLIP-seq
MIRT2349539	hsa-miR-4647	CLIP-seq
MIRT2349540	hsa-miR-466	CLIP-seq
MIRT2349541	hsa-miR-4662b	CLIP-seq
MIRT2643029	hsa-miR-4672	CLIP-seq
MIRT1426843	hsa-miR-4701-3p	CLIP-seq
MIRT1426846	hsa-miR-4710	CLIP-seq
MIRT1426849	hsa-miR-4723-3p	CLIP-seq
MIRT2643030	hsa-miR-4742-3p	CLIP-seq
MIRT2643031	hsa-miR-4752	CLIP-seq
MIRT2643032	hsa-miR-4803	CLIP-seq
MIRT2643033	hsa-miR-494	CLIP-seq
MIRT2643034	hsa-miR-505	CLIP-seq
MIRT2349548	hsa-miR-5096	CLIP-seq
MIRT1426863	hsa-miR-544b	CLIP-seq
MIRT2127858	hsa-miR-555	CLIP-seq
MIRT2643035	hsa-miR-558	CLIP-seq
MIRT2643036	hsa-miR-589	CLIP-seq
MIRT2643037	hsa-miR-599	CLIP-seq
MIRT2349549	hsa-miR-603	CLIP-seq
MIRT2127860	hsa-miR-624	CLIP-seq
MIRT2643038	hsa-miR-629	CLIP-seq
MIRT2643039	hsa-miR-644	CLIP-seq
MIRT2349550	hsa-miR-650	CLIP-seq
MIRT2643040	hsa-miR-767-3p	CLIP-seq
MIRT2643041	hsa-miR-920	CLIP-seq
MIRT1426876	hsa-miR-938	CLIP-seq
MIRT2643000	hsa-miR-1178	CLIP-seq
MIRT2127845	hsa-miR-1184	CLIP-seq
MIRT1426771	hsa-miR-1200	CLIP-seq
MIRT2127846	hsa-miR-1205	CLIP-seq
MIRT2643001	hsa-miR-1255a	CLIP-seq
MIRT2643002	hsa-miR-1255b	CLIP-seq
MIRT1426772	hsa-miR-1262	CLIP-seq
MIRT1426774	hsa-miR-1269	CLIP-seq
MIRT1426775	hsa-miR-1269b	CLIP-seq
MIRT1426777	hsa-miR-132	CLIP-seq
MIRT2643003	hsa-miR-146a	CLIP-seq
MIRT2643004	hsa-miR-146b-5p	CLIP-seq
MIRT2643005	hsa-miR-147	CLIP-seq
MIRT2127849	hsa-miR-1909	CLIP-seq
MIRT1426781	hsa-miR-1913	CLIP-seq
MIRT2643006	hsa-miR-193a-5p	CLIP-seq
MIRT1426782	hsa-miR-194	CLIP-seq
MIRT1426783	hsa-miR-1976	CLIP-seq
MIRT2643007	hsa-miR-19a	CLIP-seq
MIRT2643008	hsa-miR-19b	CLIP-seq
MIRT2643009	hsa-miR-200b	CLIP-seq
MIRT2643010	hsa-miR-200c	CLIP-seq
MIRT1426787	hsa-miR-212	CLIP-seq
MIRT1426792	hsa-miR-2467-3p	CLIP-seq
MIRT2643011	hsa-miR-31	CLIP-seq
MIRT2127852	hsa-miR-3158-5p	CLIP-seq
MIRT2643012	hsa-miR-3160-3p	CLIP-seq
MIRT2127854	hsa-miR-3173-3p	CLIP-seq
MIRT2643013	hsa-miR-3180	CLIP-seq
MIRT2643014	hsa-miR-3180-3p	CLIP-seq
MIRT1426797	hsa-miR-3183	CLIP-seq
MIRT1426798	hsa-miR-3192	CLIP-seq
MIRT2643015	hsa-miR-3196	CLIP-seq
MIRT1426799	hsa-miR-324-3p	CLIP-seq
MIRT2643016	hsa-miR-329	CLIP-seq
MIRT1426800	hsa-miR-331-3p	CLIP-seq
MIRT2349532	hsa-miR-3612	CLIP-seq
MIRT2127855	hsa-miR-3613-5p	CLIP-seq
MIRT2643017	hsa-miR-362-3p	CLIP-seq
MIRT1426806	hsa-miR-3664-5p	CLIP-seq
MIRT2643018	hsa-miR-3691-5p	CLIP-seq
MIRT2643019	hsa-miR-369-3p	CLIP-seq
MIRT2643020	hsa-miR-3911	CLIP-seq
MIRT1426813	hsa-miR-3940-5p	CLIP-seq
MIRT2643021	hsa-miR-3941	CLIP-seq
MIRT2643023	hsa-miR-429	CLIP-seq
MIRT1426816	hsa-miR-4292	CLIP-seq
MIRT1426817	hsa-miR-4297	CLIP-seq
MIRT2643025	hsa-miR-4300	CLIP-seq
MIRT1426820	hsa-miR-4324	CLIP-seq
MIRT1426821	hsa-miR-4329	CLIP-seq
MIRT2349536	hsa-miR-4426	CLIP-seq
MIRT2127856	hsa-miR-4428	CLIP-seq
MIRT1426824	hsa-miR-4462	CLIP-seq
MIRT2643027	hsa-miR-4487	CLIP-seq
MIRT2643028	hsa-miR-4494	CLIP-seq
MIRT1426832	hsa-miR-4507	CLIP-seq
MIRT1426833	hsa-miR-4520b-3p	CLIP-seq
MIRT2127857	hsa-miR-4522	CLIP-seq
MIRT1426835	hsa-miR-4529-3p	CLIP-seq
MIRT1426837	hsa-miR-455-3p	CLIP-seq
MIRT1426839	hsa-miR-4640-3p	CLIP-seq
MIRT2349539	hsa-miR-4647	CLIP-seq
MIRT2349540	hsa-miR-466	CLIP-seq
MIRT2349541	hsa-miR-4662b	CLIP-seq
MIRT2643029	hsa-miR-4672	CLIP-seq
MIRT1426843	hsa-miR-4701-3p	CLIP-seq
MIRT1426849	hsa-miR-4723-3p	CLIP-seq
MIRT2643030	hsa-miR-4742-3p	CLIP-seq
MIRT2643031	hsa-miR-4752	CLIP-seq
MIRT1426854	hsa-miR-4792	CLIP-seq
MIRT2643032	hsa-miR-4803	CLIP-seq
MIRT2643033	hsa-miR-494	CLIP-seq
MIRT2643034	hsa-miR-505	CLIP-seq
MIRT2349548	hsa-miR-5096	CLIP-seq
MIRT1426863	hsa-miR-544b	CLIP-seq
MIRT2127858	hsa-miR-555	CLIP-seq
MIRT2643035	hsa-miR-558	CLIP-seq
MIRT2643036	hsa-miR-589	CLIP-seq
MIRT2643037	hsa-miR-599	CLIP-seq
MIRT2349549	hsa-miR-603	CLIP-seq
MIRT2127860	hsa-miR-624	CLIP-seq
MIRT2643038	hsa-miR-629	CLIP-seq
MIRT2643039	hsa-miR-644	CLIP-seq
MIRT2349550	hsa-miR-650	CLIP-seq
MIRT2643040	hsa-miR-767-3p	CLIP-seq
MIRT2643041	hsa-miR-920	CLIP-seq
MIRT1426876	hsa-miR-938	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001726	Component	Ruffle	IEA
GO:0003779	Function	Actin binding	IEA
GO:0003779	Function	Actin binding	NAS	10320934
GO:0005178	Function	Integrin binding	IBA
GO:0005198	Function	Structural molecule activity	NAS	10320934
GO:0005200	Function	Structural constituent of cytoskeleton	IEA
GO:0005515	Function	Protein binding	IPI	10320934, 19234221
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0005925	Component	Focal adhesion	IBA
GO:0005925	Component	Focal adhesion	IEA
GO:0007043	Process	Cell-cell junction assembly	IEA
GO:0007043	Process	Cell-cell junction assembly	TAS	15494027
GO:0007155	Process	Cell adhesion	IEA
GO:0007155	Process	Cell adhesion	NAS	11907066
GO:0015629	Component	Actin cytoskeleton	NAS	10320934
GO:0016020	Component	Membrane	IEA
GO:0030036	Process	Actin cytoskeleton organization	IBA
GO:0045202	Component	Synapse	IEA
GO:0045202	Component	Synapse	NAS	11907066
GO:0051015	Function	Actin filament binding	IEA
GO:0070161	Component	Anchoring junction	IEA
GO:0098609	Process	Cell-cell adhesion	IBA
GO:0098793	Component	Presynapse	IEA
GO:0099140	Process	Presynaptic actin cytoskeleton organization	IDA	15479735
GO:0099140	Process	Presynaptic actin cytoskeleton organization	IMP	15479735

Other IDs

• MIM: 607349
• HGNC: 15447
• e!Ensembl: ENSG00000171914

Protein

• UniProt ID: Q9Y4G6
• Protein name: Talin-2
• Protein function: As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity (By similarity). {EC
• PDB: 6U4K
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF16511	FERM_f0	4 → 85	N-terminal or F0 domain of Talin-head FERM	Domain
  PF00373	FERM_M	203 → 316	FERM central domain	Domain
  PF09141	Talin_middle	494 → 655	Talin, middle domain	Domain
  PF01608	I_LWEQ	661 → 765	I/LWEQ domain	Family
  PF08913	VBS	1850 → 1974	Vinculin Binding Site	Domain
  PF01608	I_LWEQ	2384 → 2531	I/LWEQ domain	Family

• Sequence:

  MVALSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRK
  GIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSR
  IGITNYEEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSR
  TFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEF
  GGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVK
  YVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVK
  RWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEES
  TMLEESVSPKKSTILQQQFNRTGKAEHGSVALPAVMRSGSSGPETFNVGSMPSPQQQVMV
  GQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVD
  ESKHEIHSQVDAITAGTASVVNLTAGDPADTDYTAVGCAITTISSNLTEMSKGVKLLAAL
  MDDEVGSGEDLLRAARTLAGAVSDLLKAVQPTSGEPRQTVLTAAGSIGQASGDLLRQIGE
  NETDERFQDVLMSLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLV
  ACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAATTDSELLKQVSAAASVVSQA
  LHDLLQHVRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLV
  NAMRSDAEAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGL
  RVATNAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAVSNKNPAAQQQLVQSCKA
  VADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAM
  QLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNTVQTLKNELQDAKMAAVESQLKP
  LPGETLEKCAQDLGSTSKAVGSSMAQLLTCAAQGNEHYTGVAARETAQALKTLAQAARGV
  AASTTDPAAAHAMLDSARDVMEGSAMLIQEAKQALIAPGDAERQQRLAQVAKAVSHSLNN
  CVNCLPGQKDVDVALKSIGESSKKLLVDSLPPSTKPFQEAQSELNQAAADLNQSAGEVVH
  ATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQIQVIGNLKNISMASSKLLLA
  AKSLSVDPGAPNAKNLLAAAARAVTESINQLITLCTQQAPGQKECDNALRELETVKGMLD
  NPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTE
  AAAQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNLVDPGSSPSQVLSAATIV
  AKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKC
  RIATAPLIEAVENLTAFASNPEFVSIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTAR
  SLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQA
  SLAAVSQSLATRDDISVEALQEQLTSVVQEIGHLIDPIATAARGEAAQLGHKVTQLASYF
  EPLILAAVGVASKILDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEA
  AQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEPKGTFVDYQTTVVK
  YSKAIAVTAQEMMTKSVTNPEELGGLASQMTSDYGHLAFQGQMAAATAEPEEIGFQIRTR
  VQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACI
  TAATAVSGIIADLDTTIMFATAGTLNAENSETFADHRENILKTAKALVEDTKLLVSGAAS
  TPDKLAQAAQSSAATITQLAEVVKLGAASLGSDDPETQVVLINAIKDVAKALSDLISATK
  GAASKPVDDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIECIKQELTV
  FQSKDVPEKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDMLTAC
  KQASFHPDVSDEVRTRALRFGTECTLGYLDLLEHVLVILQKPTPEFKQQLAAFSKRVAGA
  VTELIQAAEAMKGTEWVDPEDPTVIAETELLGAAASIEAAAKKLEQLKPRAKPKQADETL
  DFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGSIPANAADDGQWSQGLISAARM
  VAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAA
  GNAVKRASDNLVRAAQKAAFGKADDDDVVVKTKFVGGIAQIIAAQEEMLKKERELEEARK
  KLAQIRQQQYKFLPTELREDEG

• Sequence length: 2542

Pathways

KEGG:

Rap1 signaling pathway
Focal adhesion
Platelet activation
Cytoskeleton in muscle cells
Shigellosis
Human T-cell leukemia virus 1 infection

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ALZHEIMER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CAMPTODACTYLY 1	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CAMPTODACTYLY OF FINGERS	—	GenCC	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CENTRAL NERVOUS SYSTEM CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CLEAR CELL RENAL CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLOR VISION DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ESOPHAGEAL DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ESOPHAGEAL ULCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GILLES DE LA TOURETTE SYNDROME	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLIOBLASTOMA MULTIFORME	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLIOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
KIDNEY CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Myoepithelial tumor	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OLIGODENDROGLIOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS, HIP	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PANCREATIC INTRADUCTAL PAPILLARY-MUCINOUS NEOPLASM	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TOURETTE SYNDROME	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Alzheimer Disease	Associate	30201328, 37354922	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Atherosclerosis	Associate	37370144	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Associate	38235137	★☆☆☆☆ Found in Text Mining only
Camptodactyly 1	Associate	27223613	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Carcinoma Hepatocellular	Associate	24761880	★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Associate	38179759	★☆☆☆☆ Found in Text Mining only
Cerebral Infarction	Associate	37370144	★☆☆☆☆ Found in Text Mining only
Drug Related Side Effects and Adverse Reactions	Associate	30201328	★☆☆☆☆ Found in Text Mining only
Erythema Infectiosum	Associate	27223613	★☆☆☆☆ Found in Text Mining only
Heart Diseases	Associate	32037394	★☆☆☆☆ Found in Text Mining only
Hippocampal Sclerosis	Associate	36674637	★☆☆☆☆ Found in Text Mining only
Hypoplastic Left Heart Syndrome	Associate	32037394	★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Associate	30201328	★☆☆☆☆ Found in Text Mining only