ZMIZ2 (zinc finger MIZ-type containing 2)
|
Gene
Gene information from NCBI Gene database.
|
|
| Entrez ID | 83637 |
| Gene name | Zinc finger MIZ-type containing 2 |
| Gene symbol | ZMIZ2 |
| Synonyms (NCBI Gene) |
NET27TRAFIP20ZIMP7hZIMP7
|
| Chromosome | 7 |
| Chromosome location | 7p13 |
| Summary | ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [P |
|
miRNA
miRNA information provided by mirtarbase database.
479
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
18
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
|
|||||||
|
|||||||
|
Protein
Protein information from UniProt database.
|
|||||||||||
|
UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
|
Q8NF64 | ||||||||||
| Protein name | Zinc finger MIZ domain-containing protein 2 (PIAS-like protein Zimp7) | ||||||||||
| Protein function | Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors. | ||||||||||
| Family and domains |
Pfam
|
||||||||||
| Tissue specificity | TISSUE SPECIFICITY: Expressed most abundantly in testis with lower levels in heart, brain, pancreas, prostate and ovary. {ECO:0000269|PubMed:16051670}. | ||||||||||
| Sequence |
|
||||||||||
| Sequence length | 920 | ||||||||||
| Interactions | View interactions | ||||||||||
|
Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
7
|
|||||||||||||||||||||||||
|
Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||