Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	8295
Gene name Gene Name - the full gene name approved by the HGNC.	Transformation/transcription domain associated protein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	TRRAP
Synonyms (NCBI Gene) Gene synonyms aliases	DEDDFA, DFNA75, PAF350/400, PAF400, STAF40, TR-AP, Tra1
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7q22.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by r

Show/Hide all(7)

SNP ID	Visualize variation	Clinical significance	Consequence
rs200157211	C>A,T	Pathogenic	Missense variant, coding sequence variant
rs1562940289	C>T	Pathogenic	Coding sequence variant, missense variant
rs1562945106	G>A	Pathogenic	Coding sequence variant, missense variant
rs1562957569	T>A	Pathogenic	Coding sequence variant, missense variant
rs1562957576	G>T	Pathogenic	Coding sequence variant, missense variant
rs1562959030	G>A	Pathogenic	Coding sequence variant, missense variant
rs1584324956	G>A	Likely-pathogenic	Missense variant, coding sequence variant

Show/Hide all(135)

miRTarBase ID	miRNA	Experiments	Reference
MIRT017022	hsa-miR-335-5p	Microarray	18185580
MIRT021348	hsa-miR-9-5p	Microarray	17612493
MIRT028429	hsa-miR-30a-5p	Proteomics	18668040
MIRT052563	hsa-let-7a-5p	CLASH	23622248
MIRT052563	hsa-let-7a-5p	CLASH	23622248
MIRT051861	hsa-let-7c-5p	CLASH	23622248
MIRT051634	hsa-let-7e-5p	CLASH	23622248
MIRT050991	hsa-miR-17-5p	CLASH	23622248
MIRT050404	hsa-miR-23a-3p	CLASH	23622248
MIRT049886	hsa-miR-31-5p	CLASH	23622248
MIRT047272	hsa-miR-181b-5p	CLASH	23622248
MIRT045381	hsa-miR-185-5p	CLASH	23622248
MIRT044338	hsa-miR-106b-5p	CLASH	23622248
MIRT043836	hsa-miR-330-3p	CLASH	23622248
MIRT041264	hsa-miR-193b-3p	CLASH	23622248
MIRT036716	hsa-miR-760	CLASH	23622248
MIRT036320	hsa-miR-1229-3p	CLASH	23622248
MIRT036039	hsa-miR-1301-3p	CLASH	23622248
MIRT1457893	hsa-miR-1197	CLIP-seq
MIRT1457894	hsa-miR-1252	CLIP-seq
MIRT1457895	hsa-miR-125a-3p	CLIP-seq
MIRT1457896	hsa-miR-1321	CLIP-seq
MIRT1457897	hsa-miR-181a	CLIP-seq
MIRT1457898	hsa-miR-181b	CLIP-seq
MIRT1457899	hsa-miR-181c	CLIP-seq
MIRT1457900	hsa-miR-181d	CLIP-seq
MIRT1457901	hsa-miR-2052	CLIP-seq
MIRT1457902	hsa-miR-27a	CLIP-seq
MIRT1457903	hsa-miR-27b	CLIP-seq
MIRT1457904	hsa-miR-3130-5p	CLIP-seq
MIRT1457905	hsa-miR-3180-5p	CLIP-seq
MIRT1457906	hsa-miR-320a	CLIP-seq
MIRT1457907	hsa-miR-320b	CLIP-seq
MIRT1457908	hsa-miR-320c	CLIP-seq
MIRT1457909	hsa-miR-320d	CLIP-seq
MIRT1457910	hsa-miR-3609	CLIP-seq
MIRT1457911	hsa-miR-3662	CLIP-seq
MIRT1457912	hsa-miR-3673	CLIP-seq
MIRT1457913	hsa-miR-3686	CLIP-seq
MIRT1457914	hsa-miR-371-5p	CLIP-seq
MIRT1457915	hsa-miR-371b-5p	CLIP-seq
MIRT1457916	hsa-miR-3934	CLIP-seq
MIRT1457917	hsa-miR-4262	CLIP-seq
MIRT1457918	hsa-miR-4419a	CLIP-seq
MIRT1457919	hsa-miR-4429	CLIP-seq
MIRT1457920	hsa-miR-4453	CLIP-seq
MIRT1457921	hsa-miR-4467	CLIP-seq
MIRT1457922	hsa-miR-4476	CLIP-seq
MIRT1457923	hsa-miR-4482	CLIP-seq
MIRT1457924	hsa-miR-4497	CLIP-seq
MIRT1457925	hsa-miR-4510	CLIP-seq
MIRT1457926	hsa-miR-4538	CLIP-seq
MIRT1457927	hsa-miR-4652-3p	CLIP-seq
MIRT1457928	hsa-miR-4659a-3p	CLIP-seq
MIRT1457929	hsa-miR-4659b-3p	CLIP-seq
MIRT1457930	hsa-miR-4698	CLIP-seq
MIRT1457931	hsa-miR-4739	CLIP-seq
MIRT1457932	hsa-miR-4756-5p	CLIP-seq
MIRT1457933	hsa-miR-486-5p	CLIP-seq
MIRT1457934	hsa-miR-488	CLIP-seq
MIRT1457935	hsa-miR-511	CLIP-seq
MIRT1457936	hsa-miR-513a-5p	CLIP-seq
MIRT1457937	hsa-miR-513c	CLIP-seq
MIRT1457938	hsa-miR-514b-5p	CLIP-seq
MIRT1457939	hsa-miR-520a-5p	CLIP-seq
MIRT1457940	hsa-miR-520d-5p	CLIP-seq
MIRT1457941	hsa-miR-524-5p	CLIP-seq
MIRT1457942	hsa-miR-525-5p	CLIP-seq
MIRT1457943	hsa-miR-548ag	CLIP-seq
MIRT1457944	hsa-miR-548ah	CLIP-seq
MIRT1457945	hsa-miR-548ai	CLIP-seq
MIRT1457946	hsa-miR-548n	CLIP-seq
MIRT1457947	hsa-miR-548t	CLIP-seq
MIRT1457948	hsa-miR-548u	CLIP-seq
MIRT1457949	hsa-miR-764	CLIP-seq
MIRT1457894	hsa-miR-1252	CLIP-seq
MIRT1457895	hsa-miR-125a-3p	CLIP-seq
MIRT2137352	hsa-miR-3194-3p	CLIP-seq
MIRT1457906	hsa-miR-320a	CLIP-seq
MIRT1457907	hsa-miR-320b	CLIP-seq
MIRT1457908	hsa-miR-320c	CLIP-seq
MIRT1457909	hsa-miR-320d	CLIP-seq
MIRT2137353	hsa-miR-338-3p	CLIP-seq
MIRT1457913	hsa-miR-3686	CLIP-seq
MIRT1457916	hsa-miR-3934	CLIP-seq
MIRT1457919	hsa-miR-4429	CLIP-seq
MIRT1457927	hsa-miR-4652-3p	CLIP-seq
MIRT2137354	hsa-miR-4727-5p	CLIP-seq
MIRT2137355	hsa-miR-4769-3p	CLIP-seq
MIRT1457933	hsa-miR-486-5p	CLIP-seq
MIRT1457940	hsa-miR-520d-5p	CLIP-seq
MIRT1457941	hsa-miR-524-5p	CLIP-seq
MIRT1457949	hsa-miR-764	CLIP-seq
MIRT2137353	hsa-miR-338-3p	CLIP-seq
MIRT1457940	hsa-miR-520d-5p	CLIP-seq
MIRT1457941	hsa-miR-524-5p	CLIP-seq
MIRT2358118	hsa-miR-548c-3p	CLIP-seq
MIRT2651550	hsa-miR-1207-5p	CLIP-seq
MIRT2651551	hsa-miR-1257	CLIP-seq
MIRT2651552	hsa-miR-1827	CLIP-seq
MIRT1457904	hsa-miR-3130-5p	CLIP-seq
MIRT1457905	hsa-miR-3180-5p	CLIP-seq
MIRT2651553	hsa-miR-3182	CLIP-seq
MIRT2137352	hsa-miR-3194-3p	CLIP-seq
MIRT1457912	hsa-miR-3673	CLIP-seq
MIRT2651554	hsa-miR-3675-5p	CLIP-seq
MIRT2651555	hsa-miR-4283	CLIP-seq
MIRT1457920	hsa-miR-4453	CLIP-seq
MIRT1457923	hsa-miR-4482	CLIP-seq
MIRT2651556	hsa-miR-4489	CLIP-seq
MIRT1457926	hsa-miR-4538	CLIP-seq
MIRT2651557	hsa-miR-4677-3p	CLIP-seq
MIRT2651558	hsa-miR-4679	CLIP-seq
MIRT2651559	hsa-miR-4738-3p	CLIP-seq
MIRT2651560	hsa-miR-4763-3p	CLIP-seq
MIRT1457934	hsa-miR-488	CLIP-seq
MIRT1457939	hsa-miR-520a-5p	CLIP-seq
MIRT1457942	hsa-miR-525-5p	CLIP-seq
MIRT2651561	hsa-miR-940	CLIP-seq
MIRT2651550	hsa-miR-1207-5p	CLIP-seq
MIRT2651551	hsa-miR-1257	CLIP-seq
MIRT2651552	hsa-miR-1827	CLIP-seq
MIRT1457904	hsa-miR-3130-5p	CLIP-seq
MIRT2651553	hsa-miR-3182	CLIP-seq
MIRT2651554	hsa-miR-3675-5p	CLIP-seq
MIRT2694213	hsa-miR-4270	CLIP-seq
MIRT2651555	hsa-miR-4283	CLIP-seq
MIRT2694214	hsa-miR-4441	CLIP-seq
MIRT1457923	hsa-miR-4482	CLIP-seq
MIRT2651556	hsa-miR-4489	CLIP-seq
MIRT2651557	hsa-miR-4677-3p	CLIP-seq
MIRT2651558	hsa-miR-4679	CLIP-seq
MIRT2651559	hsa-miR-4738-3p	CLIP-seq
MIRT2651560	hsa-miR-4763-3p	CLIP-seq
MIRT2651561	hsa-miR-940	CLIP-seq

Show/Hide all(31)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000124	Component	SAGA complex	IBA
GO:0000124	Component	SAGA complex	IDA	11564863
GO:0000124	Component	SAGA complex	NAS	9674425, 9885574, 19114550
GO:0000786	Component	Nucleosome	IDA	27153538
GO:0000812	Component	Swr1 complex	IDA	24463511
GO:0003712	Function	Transcription coregulator activity	IDA	11418595
GO:0005515	Function	Protein binding	IPI	9708738, 11418595, 15115762, 17314511, 21150319, 24981860, 35140242, 35271311
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	9708738
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005794	Component	Golgi apparatus	IDA
GO:0006282	Process	Regulation of DNA repair	NAS	11406595, 11564863
GO:0006325	Process	Chromatin organization	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IBA
GO:0006355	Process	Regulation of DNA-templated transcription	NAS	17694077
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IDA	9603525
GO:0016301	Function	Kinase activity	IKR	9708738
GO:0033276	Component	Transcription factor TFTC complex	IDA	10373431
GO:0033276	Component	Transcription factor TFTC complex	NAS	10373431
GO:0035267	Component	NuA4 histone acetyltransferase complex	IBA
GO:0035267	Component	NuA4 histone acetyltransferase complex	IDA	10966108, 14966270, 27153538
GO:0042981	Process	Regulation of apoptotic process	NAS	14966270
GO:0043484	Process	Regulation of RNA splicing	NAS	11564863
GO:0045893	Process	Positive regulation of DNA-templated transcription	NAS	18206972, 27153538
GO:0051726	Process	Regulation of cell cycle	IMP	27153538
GO:0080135	Process	Regulation of cellular response to stress	IEA
GO:0140861	Process	DNA repair-dependent chromatin remodeling	IBA
GO:1905168	Process	Positive regulation of double-strand break repair via homologous recombination	IDA	27153538
GO:2000779	Process	Regulation of double-strand break repair	NAS	14966270

MIM	HGNC	e!Ensembl
603015	12347	ENSG00000196367

Protein

UniProt ID

Q9Y4A5

Protein name

Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog)

Protein function

Adapter protein, which is found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT), which gives a specific tag for epigenetic transcription activation. Component of the NuA4 histone acetyltransferase comple

PDB

7KTR , 8H7G , 8QRI , 8XVG , 8XVV , 9C47

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02259	FAT	2849 → 3204	FAT domain	Family
PF00454	PI3_PI4_kinase	3535 → 3783	Phosphatidylinositol 3- and 4-kinase	Family

Sequence

MAFVATQGATVVDQTTLMKKYLQFVAALTDVNTPDETKLKMMQEVSENFENVTSSPQYST
FLEHIIPRFLTFLQDGEVQFLQEKPAQQLRKLVLEIIHRIPTNEHLRPHTKNVLSVMFRF
LETENEENVLICLRIIIELHKQFRPPITQEIHHFLDFVKQIYKELPKVVNRYFENPQVIP
ENTVPPPEMVGMITTIAVKVNPEREDSETRTHSIIPRGSLSLKVLAELPIIVVLMYQLYK
LNIHNVVAEFVPLIMNTIAIQVSAQARQHKLYNKELYADFIAAQIKTLSFLAYIIRIYQE
LVTKYSQQMVKGMLQLLSNCPAETAHLRKELLIAAKHILTTELRNQFIPCMDKLFDESIL
IGSGYTARETLRPLAYSTLADLVHHVRQHLPLSDLSLAVQLFAKNIDDESLPSSIQTMSC
KLLLNLVDCIRSKSEQESGNGRDVLMRMLEVFVLKFHTIARYQLSAIFKKCKPQSELGAV
EAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPPFEKQGEKDKEDKQT
FQVTDCRSLVKTLVCGVKTITWGITSCKAPGEAQFIPNKQLQPKETQIYIKLVKYAMQAL
DIYQVQIAGNGQTYIRVANCQTVRMKEEKEVLEHFAGVFTMMNPLTFKEIFQTTVPYMVE
RISKNYALQIVANSFLANPTTSALFATILVEYLLDRLPEMGSNVELSNLYLKLFKLVFGS
VSLFAAENEQMLKPHLHKIVNSSMELAQTAKEPYNYFLLLRALFRSIGGGSHDLLYQEFL
PLLPNLLQGLNMLQSGLHKQHMKDLFVELCLTVPVRLSSLLPYLPMLMDPLVSALNGSQT
LVSQGLRTLELCVDNLQPDFLYDHIQPVRAELMQALWRTLRNPADSISHVAYRVLGKFGG
SNRKMLKESQKLHYVVTEVQGPSITVEFSDCKASLQLPMEKAIETALDCLKSANTEPYYR
RQAWEVIKCFLVAMMSLEDNKHALYQLLAHPNFTEKTIPNVIISHRYKAQDTPARKTFEQ
ALTGAFMSAVIKDLRPSALPFVASLIRHYTMVAVAQQCGPFLLPCYQVGSQPSTAMFHSE
ENGSKGMDPLVLIDAIAICMAYEEKELCKIGEVALAVIFDVASIILGSKERACQLPLFSY
IVERLCACCYEQAWYAKLGGVVSIKFLMERLPLTWVLQNQQTFLKALLFVMMDLTGEVSN
GAVAMAKTTLEQLLMRCATPLKDEERAEEIVAAQEKSFHHVTHDLVREVTSPNSTVRKQA
MHSLQVLAQVTGKSVTVIMEPHKEVLQDMVPPKKHLLRHQPANAQIGLMEGNTFCTTLQP
RLFTMDLNVVEHKVFYTELLNLCEAEDSALTKLPCYKSLPSLVPLRIAALNALAACNYLP
QSREKIIAALFKALNSTNSELQEAGEACMRKFLEGATIEVDQIHTHMRPLLMMLGDYRSL
TLNVVNRLTSVTRLFPNSFNDKFCDQMMQHLRKWMEVVVITHKGGQRSDGNESISECGRC
PLSPFCQFEEMKICSAIINLFHLIPAAPQTLVKPLLEVVMKTERAMLIEAGSPFREPLIK
FLTRHPSQTVELFMMEATLNDPQWSRMFMSFLKHKDARPLRDVLAANPNRFITLLLPGGA
QTAVRPGSPSTSTMRLDLQFQAIKIISIIVKNDDSWLASQHSLVSQLRRVWVSENFQERH
RKENMAATNWKEPKLLAYCLLNYCKRNYGDIELLFQLLRAFTGRFLCNMTFLKEYMEEEI
PKNYSIAQKRALFFRFVDFNDPNFGDELKAKVLQHILNPAFLYSFEKGEGEQLLGPPNPE
GDNPESITSVFITKVLDPEKQADMLDSLRIYLLQYATLLVEHAPHHIHDNNKNRNSKLRR
LMTFAWPCLLSKACVDPACKYSGHLLLAHIIAKFAIHKKIVLQVFHSLLKAHAMEARAIV
RQAMAILTPAVPARMEDGHQMLTHWTRKIIVEEGHTVPQLVHILHLIVQHFKVYYPVRHH
LVQHMVSAMQRLGFTPSVTIEQRRLAVDLSEVVIKWELQRIKDQQPDSDMDPNSSGEGVN
SVSSSIKRGLSVDSAQEVKRFRTATGAISAVFGRSQSLPGADSLLAKPIDKQHTDTVVNF
LIRVACQVNDNTNTAGSPGEVLSRRCVNLLKTALRPDMWPKSELKLQWFDKLLMTVEQPN
QVNYGNICTGLEVLSFLLTVLQSPAILSSFKPLQRGIAACMTCGNTKVLRAVHSLLSRLM
SIFPTEPSTSSVASKYEELECLYAAVGKVIYEGLTNYEKATNANPSQLFGTLMILKSACS
NNPSYIDRLISVFMRSLQKMVREHLNPQAASGSTEATSGTSELVMLSLELVKTRLAVMSM
EMRKNFIQAILTSLIEKSPDAKILRAVVKIVEEWVKNNSPMAANQTPTLREKSILLVKMM
TYIEKRFPEDLELNAQFLDLVNYVYRDETLSGSELTAKLEPAFLSGLRCAQPLIRAKFFE
VFDNSMKRRVYERLLYVTCSQNWEAMGNHFWIKQCIELLLAVCEKSTPIGTSCQGAMLPS
ITNVINLADSHDRAAFAMVTHVKQEPRERENSESKEEDVEIDIELAPGDQTSTPKTKELS
EKDIGNQLHMLTNRHDKFLDTLREVKTGALLSAFVQLCHISTTLAEKTWVQLFPRLWKIL
SDRQQHALAGEISPFLCSGSHQVQRDCQPSALNCFVEAMSQCVPPIPIRPCVLKYLGKTH
NLWFRSTLMLEHQAFEKGLSLQIKPKQTTEFYEQESITPPQQEILDSLAELYSLLQEEDM
WAGLWQKRCKYSETATAIAYEQHGFFEQAQESYEKAMDKAKKEHERSNASPAIFPEYQLW
EDHWIRCSKELNQWEALTEYGQSKGHINPYLVLECAWRVSNWTAMKEALVQVEVSCPKEM
AWKVNMYRGYLAICHPEEQQLSFIERLVEMASSLAIREWRRLPHVVSHVHTPLLQAAQQI
IELQEAAQINAGLQPTNLGRNNSLHDMKTVVKTWRNRLPIVSDDLSHWSSIFMWRQHHYQ
GKPTWSGMHSSSIVTAYENSSQHDPSSNNAMLGVHASASAIIQYGKIARKQGLVNVALDI
LSRIHTIPTVPIVDCFQKIRQQVKCYLQLAGVMGKNECMQGLEVIESTNLKYFTKEMTAE
FYALKGMFLAQINKSEEANKAFSAAVQMHDVLVKAWAMWGDYLENIFVKERQLHLGVSAI
TCYLHACRHQNESKSRKYLAKVLWLLSFDDDKNTLADAVDKYCIGVPPIQWLAWIPQLLT
CLVGSEGKLLLNLISQVGRVYPQAVYFPIRTLYLTLKIEQRERYKSDPGPIRATAPMWRC
SRIMHMQRELHPTLLSSLEGIVDQMVWFRENWHEEVLRQLQQGLAKCYSVAFEKSGAVSD
AKITPHTLNFVKKLVSTFGVGLENVSNVSTMFSSAASESLARRAQATAQDPVFQKLKGQF
TTDFDFSVPGSMKLHNLISKLKKWIKILEAKTKQLPKFFLIEEKCRFLSNFSAQTAEVEI
PGEFLMPKPTHYYIKIARFMPRVEIVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESR
REERVLQLLRLLNPCLEKRKETTKRHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQR
CAKKGIEHDNPISRYYDRLATVQARGTQASHQVLRDILKEVQSNMVPRSMLKEWALHTFP
NATDYWTFRKMFTIQLALIGFAEFVLHLNRLNPEMLQIAQDTGKLNVAYFRFDINDATGD
LDANRPVPFRLTPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIA
WHKKTQEDTSSPLSAAGQPENMDSQQLVSLVQKAVTAIMTRLHNLAQFEGGESKVNTLVA
AANSLDNLCRMDPAWHPWL

Sequence length

3859

Interactions

View interactions

	KEGG		Reactome
	ATP-dependent chromatin remodeling Human T-cell leukemia virus 1 infection		Formation of the beta-catenin:TCF transactivating complex Ub-specific processing proteases

Show/Hide Unknown Diseases (3)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Deafness	hearing loss, autosomal dominant 75, autosomal dominant nonsyndromic hearing loss	N/A	N/A	GenCC
Hearing Loss	Hearing loss, autosomal dominant 75	N/A	N/A	ClinVar
Osteosarcoma	Osteosarcoma	PKMYT1 and TP53RK showed higher expression in osteosarcoma than in normal bone tissue, whereas TRRAP showed no significant difference. High expression of all 3 kinases was associated with relatively poor prognosis in patients with osteosarcoma.	32944406	CBGDA

Show/Hide Text Mining Associations (58)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma	Associate	29327707
Alzheimer Disease	Associate	26059363
Anemia	Associate	28471274, 36103385
Anemia Hemolytic	Associate	24969835
Apraxias	Associate	24969835
Autism Spectrum Disorder	Associate	30827496
Autistic Disorder	Associate	30827496
Bone Diseases	Associate	36103385
Brain Neoplasms	Associate	23612572
Breast Neoplasms	Inhibit	11931763
Calvarial hyperostosis	Associate	24969835
Carcinoid Tumor	Associate	29327707
Carcinoma Hepatocellular	Associate	16434963, 31188495
Carcinoma Renal Cell	Associate	37964489
Cell Transformation Neoplastic	Associate	35244540
Cholangiocarcinoma	Associate	33685460
Colonic Neoplasms	Associate	36180906
Colorectal Neoplasms	Associate	29653964, 33836681, 35244540
Constipation	Associate	24969835, 28471274, 36103385
Death	Associate	30827496
Dementia Multi Infarct	Associate	30827496
Depressive Disorder Major	Associate	30424743
Developmental Disabilities	Associate	28471274
Disease Resistance	Associate	30817817
Embryo Loss	Associate	28392909, 30424743
Episodic Ataxia	Associate	30424743
Facies	Associate	28471274
Genu valgum st Helena familial	Associate	28471274
Growth Disorders	Associate	28471274, 36103385
Hearing Loss	Associate	40004049
Hearing Loss Sensorineural	Associate	40004049
HEM dysplasia	Associate	28471274
Intellectual Disability	Associate	30827496
Learning Disabilities	Associate	30424743
Leukodystrophy Hypomyelinating with Hypodontia and Hypogonadotropic Hypogonadism	Associate	28471274
Lymphoma	Associate	29653964
Lymphoma B Cell Marginal Zone	Associate	24349473
Medulloblastoma	Associate	16618975
Melanoma	Associate	21499247
Mental Disorders	Associate	30424743
Neoplasm Recurrence Local	Associate	34326338
Neoplasms	Associate	19528463, 27664947, 33685460, 34326338
Neuroblastoma	Associate	15778291
Nonsyndromic sensorineural hearing loss	Associate	40004049
Obesity	Associate	19360007
Obsessive Compulsive Disorder	Associate	30424743
Oncogene Addiction	Associate	17233815
Osteosarcoma	Associate	32944406
Pancreatic Neoplasms	Associate	16036106, 17233815
Prostatic Neoplasms	Associate	27701467
Psychotic Disorders	Associate	30424743
Schizophrenia	Associate	30424743
Squamous Cell Carcinoma of Head and Neck	Associate	37373553
Telecanthus	Associate	30827496
Thyroid Cancer Papillary	Associate	36686473
Thyroid Hormone Resistance Syndrome	Associate	24969835, 28471274, 36103385, 36191835, 39299378
Urogenital Abnormalities	Associate	30827496
Van der Hoeve Halbertsma Waardenburg Gualdi Syndrome	Associate	30827496

TRRAP (transformation/transcription domain associated protein)