CAPZA1 (capping actin protein of muscle Z-line subunit alpha 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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829 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Capping actin protein of muscle Z-line subunit alpha 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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CAPZA1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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CAPPA1, CAPZ, CAZ1 |
Chromosome
Chromosome number
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1 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1p13.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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CAPZA1 is a member of the F-actin capping protein alpha subunit family. This gene encodes the alpha subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments. |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | P52907 | ||||||||||
Protein name | F-actin-capping protein subunit alpha-1 (CapZ alpha-1) | ||||||||||
Protein function | F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these pr | ||||||||||
PDB | 1MQ1 , 1MWN , 7T5Q , 8F8Q | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 286 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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