|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
826
|
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
Calpain small subunit 1 |
|
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
CAPNS1 |
|
Synonyms (NCBI Gene)
Gene synonyms aliases
|
CALPAIN4, CANP, CANPS, CAPN4, CDPS, CSS1, PPH6 |
|
Chromosome
Chromosome number
|
19 |
|
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
19q13.12 |
|
Summary
Summary of gene provided in NCBI Entrez Gene.
|
This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subun |
| UniProt ID |
P04632
|
| Protein name |
Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit) |
| Protein function |
Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Essential for embryonic development (By similarity). {ECO:000 |
| PDB |
1KFU
,
1KFX
,
4PHJ
,
4PHK
,
4PHM
,
4WQ2
,
4WQ3
,
5D69
,
6QLB
|
| Family and domains |
|
| Sequence |
MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR ILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATEL MNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQ FDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMF RAFKSLDKDGTGQIQVNIQEWLQLTMYS
|
|
| Sequence length |
268 |
| Interactions |
View interactions
|