CAPNS1 (calpain small subunit 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 826 |
| Gene name | Calpain small subunit 1 |
| Gene symbol | CAPNS1 |
| Synonyms (NCBI Gene) |
CALPAIN4CANPCANPSCAPN4CDPSCSS1PPH6
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| Chromosome | 19 |
| Chromosome location | 19q13.12 |
| Summary | This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subun |
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miRNA
miRNA information provided by mirtarbase database.
481
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Transcription factors
Transcription factors information provided by TRRUST V2 database.
1
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
20
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P04632 | |
| Protein name | Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit) | |
| Protein function | Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Essential for embryonic development (By similarity). {ECO:000 | |
| PDB | 1KFU , 1KFX , 4PHJ , 4PHK , 4PHM , 4WQ2 , 4WQ3 , 5D69 , 6QLB | |
| Family and domains | ||
| Sequence |
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| Sequence length | 268 | |
| Interactions | View interactions | |
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
2
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