Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	8216
Gene name Gene Name - the full gene name approved by the HGNC.	Leucine zipper like post translational regulator 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	LZTR1
Synonyms (NCBI Gene) Gene synonyms aliases	BTBD29, LZTR-1, NS10, NS2, SWNTS2
Chromosome Chromosome number	22
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	22q11.21\|22q11.1-q11.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exc

Show/Hide all(58)

SNP ID	Visualize variation	Clinical significance	Consequence
rs140874089	G>A,C	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, missense variant
rs145594158	G>A	Likely-pathogenic	Splice donor variant
rs148677674	C>A,T	Likely-pathogenic	Coding sequence variant, missense variant
rs149850248	C>G,T	Likely-pathogenic	Coding sequence variant, stop gained, missense variant
rs150419186	C>A,G,T	Pathogenic	Coding sequence variant, synonymous variant, stop gained, missense variant
rs189150283	C>T	Pathogenic	Coding sequence variant, stop gained
rs587777176	G>A	Pathogenic	Intron variant
rs587777177	C>T	Pathogenic	Coding sequence variant, missense variant
rs587777178	C>T	Pathogenic	Coding sequence variant, missense variant
rs587777179	CGCA>-	Pathogenic	Frameshift variant, coding sequence variant
rs587777180	G>A	Pathogenic	Coding sequence variant, missense variant
rs587777613	G>-,GG	Pathogenic, likely-pathogenic	Frameshift variant, coding sequence variant
rs752547717	C>T	Likely-pathogenic	Coding sequence variant, stop gained
rs753474547	TGAAGTGC>-	Likely-pathogenic	Frameshift variant, coding sequence variant
rs755783378	GTC>-	Likely-pathogenic	Inframe deletion, coding sequence variant
rs761685529	C>T	Uncertain-significance, pathogenic	Intron variant
rs762834512	G>A	Pathogenic	Coding sequence variant, missense variant
rs767191322	G>A,C,T	Likely-pathogenic	Splice donor variant
rs770933647	G>A	Pathogenic	Coding sequence variant, stop gained
rs771885420	C>A,T	Likely-pathogenic	Missense variant, coding sequence variant
rs777243508	G>A	Pathogenic	Coding sequence variant, stop gained
rs780267761	T>-	Pathogenic	Frameshift variant, coding sequence variant
rs781251567	->A	Likely-pathogenic	Frameshift variant, coding sequence variant
rs781431741	G>A	Likely-pathogenic	Missense variant, coding sequence variant
rs797045165	C>T	Pathogenic	Missense variant, coding sequence variant
rs797045166	G>A	Pathogenic	Missense variant, coding sequence variant
rs869320686	G>A	Likely-pathogenic, pathogenic	Missense variant, coding sequence variant
rs886041542	G>A,T	Likely-pathogenic	Splice donor variant
rs886041925	T>G	Likely-pathogenic	Missense variant, coding sequence variant
rs1034395178	C>A,T	Pathogenic	Synonymous variant, coding sequence variant, stop gained
rs1057518336	A>C	Likely-pathogenic	Coding sequence variant, missense variant
rs1057524046	A>C	Likely-pathogenic	Coding sequence variant, missense variant
rs1131691862	->CCGCCAG	Likely-pathogenic	Frameshift variant, coding sequence variant
rs1158550690	A>C,G	Likely-pathogenic	Splice acceptor variant
rs1185411712	C>-	Likely-pathogenic	Coding sequence variant, frameshift variant
rs1194536394	AG>-	Likely-pathogenic	Coding sequence variant, frameshift variant
rs1223430276	G>A	Uncertain-significance, likely-pathogenic	Missense variant, coding sequence variant
rs1249726034	C>A,G	Pathogenic	Intron variant
rs1302923931	G>T	Likely-pathogenic	Coding sequence variant, stop gained
rs1419091884	C>-	Likely-pathogenic	Frameshift variant, coding sequence variant
rs1458682620	A>G	Likely-pathogenic	Splice acceptor variant
rs1459786357	T>A,C	Pathogenic	5 prime UTR variant
rs1460026299	AC>-	Likely-pathogenic	Frameshift variant, coding sequence variant
rs1469540056	G>C,T	Likely-pathogenic	Missense variant, coding sequence variant
rs1555927321	T>C	Likely-pathogenic	Missense variant, coding sequence variant
rs1555927544	->T	Likely-pathogenic	Coding sequence variant, frameshift variant
rs1555927561	G>C	Likely-pathogenic	Splice donor variant
rs1555927611	T>A	Likely-pathogenic	Missense variant, coding sequence variant
rs1555927613	G>-	Likely-pathogenic	Coding sequence variant, frameshift variant
rs1555927827	G>C	Likely-pathogenic	Missense variant, coding sequence variant
rs1555928249	T>-	Pathogenic	Coding sequence variant, frameshift variant
rs1569153870	G>-	Pathogenic	Coding sequence variant, splice donor variant
rs1569154492	C>G,T	Pathogenic	Missense variant, coding sequence variant
rs1569154722	G>A	Pathogenic	Coding sequence variant, stop gained
rs1601717797	->C	Likely-pathogenic	Coding sequence variant, frameshift variant
rs1601718760	T>C	Likely-pathogenic	Missense variant, coding sequence variant
rs1601722136	->TC	Likely-pathogenic	Coding sequence variant, frameshift variant
rs1601723893	AA>TTGG	Likely-pathogenic	Coding sequence variant, frameshift variant

Show/Hide all(143)

miRTarBase ID	miRNA	Experiments	Reference
MIRT046517	hsa-miR-15b-5p	CLASH	23622248
MIRT046517	hsa-miR-15b-5p	CLASH	23622248
MIRT037967	hsa-miR-505-5p	CLASH	23622248
MIRT650834	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT650833	hsa-miR-4267	HITS-CLIP	23824327
MIRT650832	hsa-miR-4780	HITS-CLIP	23824327
MIRT650831	hsa-miR-6780b-3p	HITS-CLIP	23824327
MIRT650830	hsa-miR-370-3p	HITS-CLIP	23824327
MIRT650829	hsa-miR-6893-3p	HITS-CLIP	23824327
MIRT650828	hsa-miR-4287	HITS-CLIP	23824327
MIRT650827	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT650826	hsa-miR-1976	HITS-CLIP	23824327
MIRT650825	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT650824	hsa-miR-5699-5p	HITS-CLIP	23824327
MIRT650823	hsa-miR-3189-5p	HITS-CLIP	23824327
MIRT650822	hsa-miR-642b-5p	HITS-CLIP	23824327
MIRT650821	hsa-miR-7977	HITS-CLIP	23824327
MIRT650820	hsa-miR-623	HITS-CLIP	23824327
MIRT650818	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT650819	hsa-miR-4279	HITS-CLIP	23824327
MIRT650817	hsa-miR-4325	HITS-CLIP	23824327
MIRT650834	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT650833	hsa-miR-4267	HITS-CLIP	23824327
MIRT650832	hsa-miR-4780	HITS-CLIP	23824327
MIRT650831	hsa-miR-6780b-3p	HITS-CLIP	23824327
MIRT650830	hsa-miR-370-3p	HITS-CLIP	23824327
MIRT650829	hsa-miR-6893-3p	HITS-CLIP	23824327
MIRT650828	hsa-miR-4287	HITS-CLIP	23824327
MIRT650827	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT650826	hsa-miR-1976	HITS-CLIP	23824327
MIRT650825	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT650824	hsa-miR-5699-5p	HITS-CLIP	23824327
MIRT650823	hsa-miR-3189-5p	HITS-CLIP	23824327
MIRT650822	hsa-miR-642b-5p	HITS-CLIP	23824327
MIRT650821	hsa-miR-7977	HITS-CLIP	23824327
MIRT650820	hsa-miR-623	HITS-CLIP	23824327
MIRT650818	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT650819	hsa-miR-4279	HITS-CLIP	23824327
MIRT650817	hsa-miR-4325	HITS-CLIP	23824327
MIRT1124406	hsa-miR-1827	CLIP-seq
MIRT1124407	hsa-miR-192	CLIP-seq
MIRT1124408	hsa-miR-215	CLIP-seq
MIRT1124409	hsa-miR-219-1-3p	CLIP-seq
MIRT1124410	hsa-miR-3136-3p	CLIP-seq
MIRT1124411	hsa-miR-3192	CLIP-seq
MIRT1124412	hsa-miR-3612	CLIP-seq
MIRT1124413	hsa-miR-3661	CLIP-seq
MIRT1124414	hsa-miR-4252	CLIP-seq
MIRT1124415	hsa-miR-4286	CLIP-seq
MIRT1124416	hsa-miR-4433	CLIP-seq
MIRT1124417	hsa-miR-4443	CLIP-seq
MIRT1124418	hsa-miR-4457	CLIP-seq
MIRT1124419	hsa-miR-4519	CLIP-seq
MIRT1124420	hsa-miR-4527	CLIP-seq
MIRT1124421	hsa-miR-4530	CLIP-seq
MIRT1124422	hsa-miR-4639-5p	CLIP-seq
MIRT1124423	hsa-miR-4667-5p	CLIP-seq
MIRT1124424	hsa-miR-4700-5p	CLIP-seq
MIRT1124425	hsa-miR-4717-5p	CLIP-seq
MIRT1124426	hsa-miR-4722-5p	CLIP-seq
MIRT1124427	hsa-miR-4726-3p	CLIP-seq
MIRT1124428	hsa-miR-4743	CLIP-seq
MIRT1124429	hsa-miR-4753-5p	CLIP-seq
MIRT1124430	hsa-miR-4786-3p	CLIP-seq
MIRT1124431	hsa-miR-513b	CLIP-seq
MIRT1124432	hsa-miR-631	CLIP-seq
MIRT1124433	hsa-miR-637	CLIP-seq
MIRT1124434	hsa-miR-650	CLIP-seq
MIRT1124435	hsa-miR-940	CLIP-seq
MIRT1124410	hsa-miR-3136-3p	CLIP-seq
MIRT1124411	hsa-miR-3192	CLIP-seq
MIRT1124413	hsa-miR-3661	CLIP-seq
MIRT2035155	hsa-miR-4420	CLIP-seq
MIRT2035156	hsa-miR-4652-5p	CLIP-seq
MIRT2035157	hsa-miR-4717-3p	CLIP-seq
MIRT1124427	hsa-miR-4726-3p	CLIP-seq
MIRT2035158	hsa-miR-4778-3p	CLIP-seq
MIRT1124432	hsa-miR-631	CLIP-seq
MIRT2265599	hsa-miR-1207-5p	CLIP-seq
MIRT2265600	hsa-miR-199a-3p	CLIP-seq
MIRT2265601	hsa-miR-199b-3p	CLIP-seq
MIRT2265602	hsa-miR-2682	CLIP-seq
MIRT2265603	hsa-miR-3129-5p	CLIP-seq
MIRT2265604	hsa-miR-3177-3p	CLIP-seq
MIRT2265605	hsa-miR-3622a-5p	CLIP-seq
MIRT2265606	hsa-miR-370	CLIP-seq
MIRT2265607	hsa-miR-380	CLIP-seq
MIRT2265608	hsa-miR-412	CLIP-seq
MIRT2265609	hsa-miR-4264	CLIP-seq
MIRT2265610	hsa-miR-4269	CLIP-seq
MIRT2265611	hsa-miR-4436b-3p	CLIP-seq
MIRT2265612	hsa-miR-449c	CLIP-seq
MIRT2265613	hsa-miR-4514	CLIP-seq
MIRT2035156	hsa-miR-4652-5p	CLIP-seq
MIRT2265614	hsa-miR-4692	CLIP-seq
MIRT1124425	hsa-miR-4717-5p	CLIP-seq
MIRT2265615	hsa-miR-4758-3p	CLIP-seq
MIRT2265616	hsa-miR-4763-3p	CLIP-seq
MIRT2035158	hsa-miR-4778-3p	CLIP-seq
MIRT2265617	hsa-miR-4797-3p	CLIP-seq
MIRT1124431	hsa-miR-513b	CLIP-seq
MIRT2265618	hsa-miR-564	CLIP-seq
MIRT2265619	hsa-miR-936	CLIP-seq
MIRT1124435	hsa-miR-940	CLIP-seq
MIRT2265620	hsa-miR-942	CLIP-seq
MIRT2390434	hsa-miR-205	CLIP-seq
MIRT2390435	hsa-miR-3157-5p	CLIP-seq
MIRT2390436	hsa-miR-4690-3p	CLIP-seq
MIRT2390437	hsa-miR-548aa	CLIP-seq
MIRT2390438	hsa-miR-570	CLIP-seq
MIRT2564998	hsa-miR-1269	CLIP-seq
MIRT2564999	hsa-miR-1269b	CLIP-seq
MIRT2565000	hsa-miR-1288	CLIP-seq
MIRT2565001	hsa-miR-1343	CLIP-seq
MIRT2565002	hsa-miR-1913	CLIP-seq
MIRT2565003	hsa-miR-1972	CLIP-seq
MIRT2390434	hsa-miR-205	CLIP-seq
MIRT2565004	hsa-miR-2355-5p	CLIP-seq
MIRT2565005	hsa-miR-24	CLIP-seq
MIRT2565006	hsa-miR-2861	CLIP-seq
MIRT1124410	hsa-miR-3136-3p	CLIP-seq
MIRT2390435	hsa-miR-3157-5p	CLIP-seq
MIRT2565007	hsa-miR-324-3p	CLIP-seq
MIRT2565008	hsa-miR-3657	CLIP-seq
MIRT2265606	hsa-miR-370	CLIP-seq
MIRT2565009	hsa-miR-3909	CLIP-seq
MIRT2565010	hsa-miR-4323	CLIP-seq
MIRT2565011	hsa-miR-450b-3p	CLIP-seq
MIRT2565012	hsa-miR-4512	CLIP-seq
MIRT2565013	hsa-miR-4515	CLIP-seq
MIRT2565014	hsa-miR-4669	CLIP-seq
MIRT2390436	hsa-miR-4690-3p	CLIP-seq
MIRT2565015	hsa-miR-4713-3p	CLIP-seq
MIRT1124425	hsa-miR-4717-5p	CLIP-seq
MIRT2565016	hsa-miR-4740-5p	CLIP-seq
MIRT2565017	hsa-miR-4755-3p	CLIP-seq
MIRT2265615	hsa-miR-4758-3p	CLIP-seq
MIRT1124430	hsa-miR-4786-3p	CLIP-seq
MIRT2565018	hsa-miR-638	CLIP-seq
MIRT2565019	hsa-miR-769-3p	CLIP-seq
MIRT2565001	hsa-miR-1343	CLIP-seq
MIRT2565004	hsa-miR-2355-5p	CLIP-seq
MIRT1124410	hsa-miR-3136-3p	CLIP-seq

Show/Hide all(16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	19060904, 29892012, 32296183, 35512704
GO:0005768	Component	Endosome	IEA
GO:0005794	Component	Golgi apparatus	IBA
GO:0005794	Component	Golgi apparatus	IDA	16356934
GO:0005794	Component	Golgi apparatus	IEA
GO:0012505	Component	Endomembrane system	IDA	30442762, 30442766
GO:0012505	Component	Endomembrane system	IEA
GO:0016020	Component	Membrane	IEA
GO:0016567	Process	Protein ubiquitination	IDA	30442762, 30442766
GO:0016567	Process	Protein ubiquitination	IEA
GO:0031267	Function	Small GTPase binding	IDA	30442762, 30442766
GO:0031463	Component	Cul3-RING ubiquitin ligase complex	IDA	30442762, 30442766
GO:0046580	Process	Negative regulation of Ras protein signal transduction	IDA	30442762, 30442766
GO:0046580	Process	Negative regulation of Ras protein signal transduction	IEA
GO:0055037	Component	Recycling endosome	IEA
GO:0055038	Component	Recycling endosome membrane	IDA	30442762

MIM	HGNC	e!Ensembl
600574	6742	ENSG00000099949

Protein

UniProt ID

Q8N653

Protein name

Leucine-zipper-like transcriptional regulator 1 (LZTR-1)

Protein function

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates ubiquitination of Ras (K-Ras/KRAS, N-Ras/NRAS and H-Ras/HRAS) (PubMed:30442762, PubMed:30442766, PubMed:30481304). Is a negative regulator of R

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13418	Kelch_4	67 → 116		Repeat
PF07646	Kelch_2	117 → 166	Kelch motif	Repeat
PF01344	Kelch_1	227 → 270	Kelch motif	Repeat
PF01344	Kelch_1	283 → 328	Kelch motif	Repeat
PF00651	BTB	433 → 573	BTB/POZ domain	Domain
PF00651	BTB	656 → 767	BTB/POZ domain	Domain

Sequence

MAGPGSTGGQIGAAALAGGARSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPC
DEFVGARRSKHTVVAYKDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYH
HSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGA
TVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFPVAVCRDKM
FVFSGQSGAKITNNLFQFEFKDKTWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFG
GAADNTLPNELHCYDVDFQTWEVVQPSSDSEVGGAEVPERACASEEVPTLTYEERVGFKK
SRDVFGLDFGTTSAKQPTQPASELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQ
FSCYPKCTLHEDYGRLWESRQFCDVEFVLGEKEECVQGHVAIVTARSRWLRRKITQARER
LAQKLEQEAAPVPREAPGVAAGGARPPLLHVAIREAEARPFEVLMQFLYTDKIKYPRKGH
VEDVLLIMDVYKLALSFQLCRLEQLCRQYIEASVDLQNVLVVCESAARLQLSQLKEHCLN
FVVKESHFNQVIMMKEFERLSSPLIVEIVRRKQQPPPRTPLDQPVDIGTSLIQDMKAYLE
GAGAEFCDITLLLDGHPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSRQAF
ESMLRYIYYGEVNMPPEDSLYLFAAPYYYGFYNNRLQAYCKQNLEMNVTVQNVLQILEAA
DKTQALDMKRHCLHIIVHQFTKVSKLPTLRSLSQQLLLDIIDSLASHISDKQCAELGADI

Sequence length

840

Interactions

View interactions

Show/Hide Causal Diseases (5)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Noonan Syndrome	noonan syndrome 2, Noonan syndrome and Noonan-related syndrome, noonan syndrome 1, noonan syndrome, noonan syndrome 10	rs587777179, rs1223430276, rs189150283, rs761685529, rs587777180, rs1249726034, rs1034395178, rs1194536394, rs587777613, rs150419186, rs1555928249, rs781431741, rs145594158, rs1601718760, rs869320686 View all (8 more)	N/A
Schwannomatosis	schwannomatosis	rs189150283, rs1555927561, rs587777180, rs1460026299, rs148031742, rs149850248	N/A
autism spectrum disorder	Autism spectrum disorder	rs780267761	N/A
Male infertility	male infertility with azoospermia or oligozoospermia due to single gene mutation	rs781431741	N/A
neoplasm	Neoplasm	rs587777613	N/A

Show/Hide Unknown Diseases (5)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Acute Myeloid Leukemia	Acute myeloid leukemia	Reduced expression levels of LZTR1, NF1, TSC1, and TSC2 correlate with reduced sensitivity to sorafenib in samples from patients with acute myeloid leukemia and deficiency results in hyperactivation of MAPK or MTOR pathways in acute myeloid leukemia cells	33375770	CBGDA
Bladder Exstrophy	bladder exstrophy	N/A	N/A	ClinVar
Breast Cancer	breast cancer	N/A	N/A	GenCC
Congenital diaphragmatic hernia	congenital diaphragmatic hernia	N/A	N/A	ClinVar
Nonimmune Hydrops Fetalis	non-immune hydrops fetalis	N/A	N/A	ClinVar

Show/Hide Text Mining Associations (53)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma	Associate	36304963
Adrenocortical Carcinoma	Associate	36304963
Astrocytoma	Associate	30664951
Autistic Disorder	Associate	25961944
Bladder Exstrophy	Associate	34355505, 36349425, 37509153
Bladder Exstrophy and Epispadias Complex	Associate	37509153
Breast Neoplasms	Associate	40724954
Carcinogenesis	Associate	36304963, 37626065
Carcinoma Hepatocellular	Associate	28622513, 36304963
Cardiomyopathy Dilated	Associate	39577308
Cardiomyopathy Hypertrophic	Associate	30732632, 33568805
Cell Transformation Neoplastic	Associate	36304963
Choroidal Effusions	Associate	33568805
Conotruncal cardiac defects	Associate	22185286
Coronary Artery Disease	Associate	37143668
COVID 19	Associate	37143668
Depressive Disorder	Associate	36609239
Developmental Disabilities	Associate	30859559
DiGeorge Syndrome	Inhibit	16356934
DiGeorge Syndrome	Associate	22185286, 33879870
Dowling Degos Disease	Associate	30859559
Edema	Associate	33568805
Esophageal Neoplasms	Stimulate	36304963
Genetic Diseases Inborn	Associate	24362817
Glioblastoma	Associate	23917401, 30664951, 31337872
Glioma	Associate	23917401, 30664951
Heart Diseases	Associate	39577308
Hereditary renal agenesis	Associate	33824538
Histiocytic Sarcoma	Associate	31439678
Leukemia	Associate	35904492
Leukemia Myeloid Acute	Associate	33375770
Melanoma	Associate	35197475
Neoplasm Metastasis	Associate	35197475, 37626065
Neoplasms	Associate	25335493, 25480913, 29069277, 29384852, 30664951, 33025139, 34659131, 36304963
Neoplasms	Inhibit	35197475, 37626065
Neurilemmoma	Associate	24362817, 27856782, 28759666, 29384852, 32281771, 33025139, 35361920
Neurilemmoma	Inhibit	35391499
Neurofibromatosis 2	Associate	29409008
Neuroma Acoustic	Associate	25480913, 27856782, 33879870
Noonan like syndrome	Associate	30859559
Noonan Syndrome	Associate	29469822, 30664951, 30732632, 30859559, 31337872, 32514133, 35656879, 36609239, 37143668, 38254922, 39577308
Noonan Syndrome 2	Associate	29469822
Pain	Associate	29384852
Pancreatic Neoplasms	Associate	35114566
Precancerous Conditions	Associate	36304963
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	37143668
Schwannomatosis	Associate	24362817, 25335493, 25480913, 27856782, 29384852, 29409008, 30664951, 31337872, 31424590, 31438995, 32281771, 33025139, 33269527, 33879870, 35361920, 35391499, 35732500, 39577308 View all (3 more)
Squamous Cell Carcinoma of Head and Neck	Stimulate	36304963
Stillbirth	Associate	29469822
Stomach Neoplasms	Associate	36484990
Urinary Bladder Neoplasms	Associate	36304963
Uveal melanoma	Associate	36304963
Williams Beuren Region Duplication Syndrome	Associate	33269527

LZTR1 (leucine zipper like post translational regulator 1)