Gene Gene information from NCBI Gene database.
Entrez ID 821
Gene name Calnexin
Gene symbol CANX
Synonyms (NCBI Gene)
CNXIP90P90
Chromosome 5
Chromosome location 5q35.3
Summary This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating prote
miRNA miRNA information provided by mirtarbase database.
1308
miRTarBase ID miRNA Experiments Reference
MIRT050869 hsa-miR-17-5p CLASH 23622248
MIRT050692 hsa-miR-18a-5p CLASH 23622248
MIRT048231 hsa-miR-196a-5p CLASH 23622248
MIRT046689 hsa-miR-222-3p CLASH 23622248
MIRT045334 hsa-miR-185-5p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
38
GO ID Ontology Definition Evidence Reference
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0005509 Function Calcium ion binding IBA
GO:0005509 Function Calcium ion binding IEA
GO:0005509 Function Calcium ion binding TAS 8136357
GO:0005515 Function Protein binding IPI 16361248, 16546175, 17110338, 17220478, 17380188, 20528919, 21205830, 22190034, 22314232, 22872700, 23826168, 24764305, 25170080, 26496610, 26618866, 28514442, 29568061, 29765154, 29924966, 30021884, 31324722, 31735293, 32783947, 32814053, 33961781, 35271311, 36012204
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
114217 1473 ENSG00000127022
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P27824
Protein name Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Protein function Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems t
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00262 Calreticulin 71 440 Calreticulin family Family
Sequence
Sequence length 592
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Protein processing in endoplasmic reticulum
Phagosome
Antigen processing and presentation
Thyroid hormone synthesis
Human T-cell leukemia virus 1 infection
  Assembly of Viral Components at the Budding Site
MHC class II antigen presentation
Interleukin-35 Signalling
Calnexin/calreticulin cycle
Interleukin-27 signaling
Antigen Presentation: Folding, assembly and peptide loading of class I MHC