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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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8208
|
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Chromatin assembly factor 1 subunit B |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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CHAF1B |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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CAF-1, CAF-IP60, CAF1, CAF1A, CAF1P60, MPHOSPH7, MPP7 |
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Chromosome
Chromosome number
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21 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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21q22.12-q22.13 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is require |
| UniProt ID |
Q13112
|
| Protein name |
Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-I p60) (M-phase phosphoprotein 7) |
| Protein function |
Acts as a component of the histone chaperone complex chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto DNA during replication and repair. CAF-1 performs the first step of the nucleosome assembly process, bringing newly s |
| PDB |
7Y5K
,
7Y5L
,
7Y5O
,
7Y5U
,
7Y5V
,
7Y60
,
7Y61
,
8IQF
,
8IQG
,
8J6S
,
8J6T
|
| Family and domains |
Pfam
| Accession |
ID |
Position in sequence |
Description |
Type |
|
PF00400
|
WD40 |
57 → 94 |
WD domain, G-beta repeat |
Repeat |
|
PF00400
|
WD40 |
119 → 157 |
WD domain, G-beta repeat |
Repeat |
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PF00400
|
WD40 |
161 → 199 |
WD domain, G-beta repeat |
Repeat |
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PF15512
|
CAF-1_p60_C |
381 → 555 |
Chromatin assembly factor complex 1 subunit p60, C-terminal |
Domain |
|
| Sequence |
|
| Sequence length |
559 |
| Interactions |
View interactions
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