RAB1B (RAB1B, member RAS oncogene family)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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81876 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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RAB1B, member RAS oncogene family |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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RAB1B |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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- |
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Chromosome
Chromosome number
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11 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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11q13.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport b |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q9H0U4 | ||||||||||
| Protein name | Ras-related protein Rab-1B (EC 3.6.5.2) | ||||||||||
| Protein function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (PubMed:20545908, PubMed:9437002, PubMed:23236136). Rabs cycle between an inactive GDP-bound | ||||||||||
| PDB | 3JZA , 3NKV , 4HLQ , 4I1O , 5O74 , 5SZH , 5SZK , 6SKU , 8ALK | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 201 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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