Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
81876
Gene name Gene Name - the full gene name approved by the HGNC.
RAB1B, member RAS oncogene family
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
RAB1B
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
11q13.2
Summary Summary of gene provided in NCBI Entrez Gene.
Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport b
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT004695 hsa-miR-107 Flow, Immunoblot, Microarray, qRT-PCR 19688090
MIRT020151 hsa-miR-130b-3p Sequencing 20371350
MIRT025973 hsa-miR-148a-3p Sequencing 20371350
MIRT027096 hsa-miR-103a-3p Sequencing 20371350
MIRT031730 hsa-miR-16-5p Sequencing 20371350
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000045 Process Autophagosome assembly IBA 21873635
GO:0000139 Component Golgi membrane TAS
GO:0003924 Function GTPase activity IBA 21873635
GO:0005515 Function Protein binding IPI 15796781, 21378754, 22011575, 25107275, 26824392, 26977884, 28514442, 31046837, 32296183
GO:0005525 Function GTP binding IDA 20937701
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
612565 18370 ENSG00000174903
Protein
UniProt ID Q9H0U4
Protein name Ras-related protein Rab-1B (EC 3.6.5.2)
Protein function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (PubMed:20545908, PubMed:9437002, PubMed:23236136). Rabs cycle between an inactive GDP-bound
PDB 3JZA , 3NKV , 4HLQ , 4I1O , 5O74 , 5SZH , 5SZK , 6SKU , 8ALK
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00071 Ras 10 171 Ras family Domain
Sequence
Sequence length 201
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Legionellosis   Golgi Cisternae Pericentriolar Stack Reorganization
COPII-mediated vesicle transport
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Insomnia Insomnia GWAS
Associations from Text Mining
Disease Name Relationship Type References
Breast Neoplasms Associate 32432324
Carcinoma Hepatocellular Stimulate 12450215
Carcinoma Non Small Cell Lung Associate 32710726
Colorectal Neoplasms Associate 28316326
Intervertebral Disc Degeneration Associate 34939437
Lymphatic Metastasis Stimulate 28316326
Nasopharyngeal Carcinoma Associate 36606322
Neoplasm Metastasis Stimulate 32432324
Neoplasms Associate 28316326, 36606322