Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	81853
Gene name Gene Name - the full gene name approved by the HGNC.	Transmembrane protein 14B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	TMEM14B
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6p24.2

Show/Hide all(104)

miRTarBase ID	miRNA	Experiments
MIRT1431381	hsa-miR-1245b-3p	CLIP-seq
MIRT1431382	hsa-miR-1470	CLIP-seq
MIRT1431383	hsa-miR-3143	CLIP-seq
MIRT1431384	hsa-miR-3145-3p	CLIP-seq
MIRT1431385	hsa-miR-331-5p	CLIP-seq
MIRT1431386	hsa-miR-3662	CLIP-seq
MIRT1431387	hsa-miR-3692	CLIP-seq
MIRT1431388	hsa-miR-374c	CLIP-seq
MIRT1431389	hsa-miR-3973	CLIP-seq
MIRT1431390	hsa-miR-4325	CLIP-seq
MIRT1431391	hsa-miR-4711-3p	CLIP-seq
MIRT1431392	hsa-miR-4753-3p	CLIP-seq
MIRT1431393	hsa-miR-4768-5p	CLIP-seq
MIRT1431394	hsa-miR-4793-3p	CLIP-seq
MIRT1431395	hsa-miR-4803	CLIP-seq
MIRT1431396	hsa-miR-511	CLIP-seq
MIRT1431397	hsa-miR-520g	CLIP-seq
MIRT1431398	hsa-miR-520h	CLIP-seq
MIRT1431399	hsa-miR-607	CLIP-seq
MIRT1431400	hsa-miR-622	CLIP-seq
MIRT1431401	hsa-miR-655	CLIP-seq
MIRT1431383	hsa-miR-3143	CLIP-seq
MIRT1554889	hsa-miR-4780	CLIP-seq
MIRT1554890	hsa-miR-543	CLIP-seq
MIRT1431383	hsa-miR-3143	CLIP-seq
MIRT1431388	hsa-miR-374c	CLIP-seq
MIRT2129297	hsa-miR-4311	CLIP-seq
MIRT1431392	hsa-miR-4753-3p	CLIP-seq
MIRT1431393	hsa-miR-4768-5p	CLIP-seq
MIRT1554889	hsa-miR-4780	CLIP-seq
MIRT1554890	hsa-miR-543	CLIP-seq
MIRT1431401	hsa-miR-655	CLIP-seq
MIRT2129297	hsa-miR-4311	CLIP-seq
MIRT2350847	hsa-miR-1208	CLIP-seq
MIRT1431383	hsa-miR-3143	CLIP-seq
MIRT2350848	hsa-miR-377	CLIP-seq
MIRT2350849	hsa-miR-3921	CLIP-seq
MIRT1431389	hsa-miR-3973	CLIP-seq
MIRT2350850	hsa-miR-4303	CLIP-seq
MIRT1431390	hsa-miR-4325	CLIP-seq
MIRT2350851	hsa-miR-4326	CLIP-seq
MIRT2350852	hsa-miR-4426	CLIP-seq
MIRT2350853	hsa-miR-4468	CLIP-seq
MIRT2350854	hsa-miR-4647	CLIP-seq
MIRT2350855	hsa-miR-4653-5p	CLIP-seq
MIRT2350856	hsa-miR-4662b	CLIP-seq
MIRT1554889	hsa-miR-4780	CLIP-seq
MIRT1431394	hsa-miR-4793-3p	CLIP-seq
MIRT1431395	hsa-miR-4803	CLIP-seq
MIRT2350857	hsa-miR-5096	CLIP-seq
MIRT1431397	hsa-miR-520g	CLIP-seq
MIRT1431398	hsa-miR-520h	CLIP-seq
MIRT1554890	hsa-miR-543	CLIP-seq
MIRT2350858	hsa-miR-548p	CLIP-seq
MIRT2350859	hsa-miR-601	CLIP-seq
MIRT1431399	hsa-miR-607	CLIP-seq
MIRT1431400	hsa-miR-622	CLIP-seq
MIRT2395934	hsa-miR-3127-5p	CLIP-seq
MIRT1431383	hsa-miR-3143	CLIP-seq
MIRT1431389	hsa-miR-3973	CLIP-seq
MIRT1554889	hsa-miR-4780	CLIP-seq
MIRT1431395	hsa-miR-4803	CLIP-seq
MIRT2395935	hsa-miR-513c	CLIP-seq
MIRT2395936	hsa-miR-514b-5p	CLIP-seq
MIRT1431397	hsa-miR-520g	CLIP-seq
MIRT1431398	hsa-miR-520h	CLIP-seq
MIRT1554890	hsa-miR-543	CLIP-seq
MIRT1431399	hsa-miR-607	CLIP-seq
MIRT1431383	hsa-miR-3143	CLIP-seq
MIRT1431389	hsa-miR-3973	CLIP-seq
MIRT1431395	hsa-miR-4803	CLIP-seq
MIRT1431397	hsa-miR-520g	CLIP-seq
MIRT1431398	hsa-miR-520h	CLIP-seq
MIRT1431399	hsa-miR-607	CLIP-seq
MIRT1431400	hsa-miR-622	CLIP-seq
MIRT1431383	hsa-miR-3143	CLIP-seq
MIRT1554889	hsa-miR-4780	CLIP-seq
MIRT1554890	hsa-miR-543	CLIP-seq
MIRT2644494	hsa-miR-1178	CLIP-seq
MIRT2644495	hsa-miR-1272	CLIP-seq
MIRT2644496	hsa-miR-1322	CLIP-seq
MIRT1431382	hsa-miR-1470	CLIP-seq
MIRT2644497	hsa-miR-197	CLIP-seq
MIRT2644498	hsa-miR-296-3p	CLIP-seq
MIRT2644499	hsa-miR-300	CLIP-seq
MIRT2644500	hsa-miR-3137	CLIP-seq
MIRT1431383	hsa-miR-3143	CLIP-seq
MIRT2644501	hsa-miR-3163	CLIP-seq
MIRT2644502	hsa-miR-3675-3p	CLIP-seq
MIRT1431387	hsa-miR-3692	CLIP-seq
MIRT2644503	hsa-miR-374a	CLIP-seq
MIRT2644504	hsa-miR-374b	CLIP-seq
MIRT2644505	hsa-miR-381	CLIP-seq
MIRT2129297	hsa-miR-4311	CLIP-seq
MIRT2644506	hsa-miR-4666-3p	CLIP-seq
MIRT2644507	hsa-miR-4666-5p	CLIP-seq
MIRT2644508	hsa-miR-4668-3p	CLIP-seq
MIRT1554889	hsa-miR-4780	CLIP-seq
MIRT1554890	hsa-miR-543	CLIP-seq
MIRT2644509	hsa-miR-577	CLIP-seq
MIRT1431383	hsa-miR-3143	CLIP-seq
MIRT2129297	hsa-miR-4311	CLIP-seq
MIRT1554889	hsa-miR-4780	CLIP-seq
MIRT1554890	hsa-miR-543	CLIP-seq

Show/Hide all(9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	29033352, 32296183, 36217029
GO:0006783	Process	Heme biosynthetic process	IBA
GO:0007399	Process	Nervous system development	IEA
GO:0016020	Component	Membrane	IEA
GO:0021987	Process	Cerebral cortex development	IMP	29033352
GO:0031966	Component	Mitochondrial membrane	IBA
GO:0042802	Function	Identical protein binding	IPI	32296183
GO:0061351	Process	Neural precursor cell proliferation	IDA	29033352
GO:2000045	Process	Regulation of G1/S transition of mitotic cell cycle	IDA	29033352

MIM	HGNC	e!Ensembl
619865	21384	ENSG00000137210

Protein

UniProt ID

Q9NUH8

Protein name

Transmembrane protein 14B

Protein function

Primate-specific protein involved in cortical expansion and folding in the developing neocortex. May drive neural progenitor proliferation through nuclear translocation of IQGAP1, which in turn promotes G1/S cell cycle transitions. {ECO:0000269|

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03647	Tmemb_14	13 → 105	Transmembrane proteins 14C	Family

Tissue specificity

TISSUE SPECIFICITY: Mainly expressed in the outer subventricular zone (OSVZ) of the fetal brains. {ECO:0000269|PubMed:29033352}.

Sequence

MEKPLFPLVPLHWFGFGYTALVVSGGIVGYVKTGSVPSLAAGLLFGSLAGLGAYQLYQDP
RNVWGFLAATSVTFVGVMGMRSYYYGKFMPVGLIAGASLLMAAKVGVRMLMTSD

Sequence length

114

Interactions

View interactions

Show/Hide Unknown Diseases (2)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Alzheimer disease	Alzheimer's disease or family history of Alzheimer's disease	N/A	N/A	GWAS
Otosclerosis	Otosclerosis	N/A	N/A	GWAS

Show/Hide Text Mining Associations (2)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Carcinoma Hepatocellular	Associate	37380717
Neuroblastoma	Associate	36037157

TMEM14B (transmembrane protein 14B)