Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	81796
Gene name	Solute carrier organic anion transporter family member 5A1
Gene symbol	SLCO5A1
Synonyms (NCBI Gene)	OATP-JOATP-RP4OATP5A1OATPJOATPRP4SLC21A15
Chromosome	8
Chromosome location	8q13.3
Summary	This gene encodes a 12 transmembrane domain protein that is a member of the solute carrier organic anion transporter superfamily. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]

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Show/Hide all (119)

miRTarBase ID	miRNA	Experiments	Reference
MIRT653404	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT653403	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT680449	hsa-miR-3183	HITS-CLIP	23824327
MIRT680448	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT680447	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT653402	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT653401	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT653400	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT653399	hsa-miR-3926	HITS-CLIP	23824327
MIRT680446	hsa-miR-4684-5p	HITS-CLIP	23824327
MIRT653398	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT653397	hsa-miR-548s	HITS-CLIP	23824327
MIRT639921	hsa-miR-548b-3p	HITS-CLIP	23824327
MIRT639920	hsa-miR-4511	HITS-CLIP	23824327
MIRT675665	hsa-miR-4731-3p	HITS-CLIP	23824327
MIRT675664	hsa-miR-4801	HITS-CLIP	23824327
MIRT639919	hsa-miR-8485	HITS-CLIP	23824327
MIRT639918	hsa-miR-603	HITS-CLIP	23824327
MIRT653404	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT653403	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT653402	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT653401	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT653400	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT653399	hsa-miR-3926	HITS-CLIP	23824327
MIRT653398	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT653397	hsa-miR-548s	HITS-CLIP	23824327
MIRT653404	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT653403	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT653402	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT653401	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT653400	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT653399	hsa-miR-3926	HITS-CLIP	23824327
MIRT653398	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT653397	hsa-miR-548s	HITS-CLIP	23824327
MIRT639921	hsa-miR-548b-3p	HITS-CLIP	23824327
MIRT639920	hsa-miR-4511	HITS-CLIP	23824327
MIRT639919	hsa-miR-8485	HITS-CLIP	23824327
MIRT639918	hsa-miR-603	HITS-CLIP	23824327
MIRT442556	hsa-miR-548az-5p	PAR-CLIP	22100165
MIRT442555	hsa-miR-548t-5p	PAR-CLIP	22100165
MIRT442554	hsa-miR-106a-5p	PAR-CLIP	22100165
MIRT442553	hsa-miR-106b-5p	PAR-CLIP	22100165
MIRT442552	hsa-miR-17-5p	PAR-CLIP	22100165
MIRT442551	hsa-miR-20a-5p	PAR-CLIP	22100165
MIRT442550	hsa-miR-20b-5p	PAR-CLIP	22100165
MIRT442549	hsa-miR-519d-3p	PAR-CLIP	22100165
MIRT442548	hsa-miR-526b-3p	PAR-CLIP	22100165
MIRT442547	hsa-miR-93-5p	PAR-CLIP	22100165
MIRT442546	hsa-miR-192-3p	PAR-CLIP	22100165
MIRT675665	hsa-miR-4731-3p	HITS-CLIP	27418678
MIRT675664	hsa-miR-4801	HITS-CLIP	27418678
MIRT639918	hsa-miR-603	HITS-CLIP	27418678
MIRT639918	hsa-miR-603	HITS-CLIP	27418678
MIRT639919	hsa-miR-8485	HITS-CLIP	27418678
MIRT639919	hsa-miR-8485	HITS-CLIP	27418678
MIRT653404	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT653403	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT680449	hsa-miR-3183	HITS-CLIP	23824327
MIRT680448	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT680447	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT653402	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT653401	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT653400	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT653399	hsa-miR-3926	HITS-CLIP	23824327
MIRT680446	hsa-miR-4684-5p	HITS-CLIP	23824327
MIRT653398	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT653397	hsa-miR-548s	HITS-CLIP	23824327
MIRT639921	hsa-miR-548b-3p	HITS-CLIP	23824327
MIRT639920	hsa-miR-4511	HITS-CLIP	23824327
MIRT675665	hsa-miR-4731-3p	HITS-CLIP	23824327
MIRT675664	hsa-miR-4801	HITS-CLIP	23824327
MIRT639919	hsa-miR-8485	HITS-CLIP	23824327
MIRT639918	hsa-miR-603	HITS-CLIP	23824327
MIRT653404	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT653403	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT653402	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT653401	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT653400	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT653399	hsa-miR-3926	HITS-CLIP	23824327
MIRT653398	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT653397	hsa-miR-548s	HITS-CLIP	23824327
MIRT653404	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT653403	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT653402	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT653401	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT653400	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT653399	hsa-miR-3926	HITS-CLIP	23824327
MIRT653398	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT653397	hsa-miR-548s	HITS-CLIP	23824327
MIRT639921	hsa-miR-548b-3p	HITS-CLIP	23824327
MIRT639920	hsa-miR-4511	HITS-CLIP	23824327
MIRT639919	hsa-miR-8485	HITS-CLIP	23824327
MIRT639918	hsa-miR-603	HITS-CLIP	23824327
MIRT442556	hsa-miR-548az-5p	PAR-CLIP	22100165
MIRT442555	hsa-miR-548t-5p	PAR-CLIP	22100165
MIRT442554	hsa-miR-106a-5p	PAR-CLIP	22100165
MIRT442553	hsa-miR-106b-5p	PAR-CLIP	22100165
MIRT442552	hsa-miR-17-5p	PAR-CLIP	22100165
MIRT442551	hsa-miR-20a-5p	PAR-CLIP	22100165
MIRT442550	hsa-miR-20b-5p	PAR-CLIP	22100165
MIRT442549	hsa-miR-519d-3p	PAR-CLIP	22100165
MIRT442548	hsa-miR-526b-3p	PAR-CLIP	22100165
MIRT442547	hsa-miR-93-5p	PAR-CLIP	22100165
MIRT442546	hsa-miR-192-3p	PAR-CLIP	22100165
MIRT1369487	hsa-miR-3137	CLIP-seq
MIRT1369488	hsa-miR-4711-3p	CLIP-seq
MIRT1369489	hsa-miR-4732-5p	CLIP-seq
MIRT1369490	hsa-miR-592	CLIP-seq
MIRT1369491	hsa-miR-599	CLIP-seq
MIRT2332969	hsa-miR-1206	CLIP-seq
MIRT2332970	hsa-miR-128	CLIP-seq
MIRT2332971	hsa-miR-27a	CLIP-seq
MIRT2332972	hsa-miR-27b	CLIP-seq
MIRT2627316	hsa-miR-3691-3p	CLIP-seq
MIRT2627317	hsa-miR-3978	CLIP-seq
MIRT2627318	hsa-miR-4480	CLIP-seq
MIRT2627316	hsa-miR-3691-3p	CLIP-seq
MIRT2627317	hsa-miR-3978	CLIP-seq
MIRT2627318	hsa-miR-4480	CLIP-seq

Show/Hide all (8)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005886	Component	Plasma membrane	IDA	21278488
GO:0005886	Component	Plasma membrane	IEA
GO:0015347	Function	Sodium-independent organic anion transmembrane transporter activity	IBA
GO:0016020	Component	Membrane	IEA
GO:0016323	Component	Basolateral plasma membrane	IBA
GO:0022857	Function	Transmembrane transporter activity	IEA
GO:0043252	Process	Sodium-independent organic anion transport	IBA
GO:0055085	Process	Transmembrane transport	IEA

MIM	HGNC	e!Ensembl
613543	19046	ENSG00000137571

Q9H2Y9

Protein name

Solute carrier organic anion transporter family member 5A1 (Organic anion transporter polypeptide-related protein 4) (OATP-RP4) (OATPRP4) (Solute carrier family 21 member 15)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03137	OATP	129 → 734	Organic Anion Transporter Polypeptide (OATP) family	Family
PF07648	Kazal_2	556 → 603	Kazal-type serine protease inhibitor domain	Domain

Sequence

MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA
FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL
YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV
VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG
NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL
YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL
VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRD
LPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVP
SAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT
GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE
CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF
ITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQEC
GVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQRRRQREFPLSTV
SERVGHPDNARTRSCPAFSTQGEFHEETGLQKGIQCAAQTYPGPFPEAISSSADPGLEES
PAALEPPS

Sequence length

848

Interactions

View interactions

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Clear cell carcinoma of kidney	Benign; Likely benign	rs34036248	RCV005921385
Familial cancer of breast	Benign; Likely benign	rs34036248	RCV005921384
SLCO5A1-related disorder	Benign; Likely benign	rs34036248, rs192452408	RCV003933411 RCV003951002
Thyroid cancer, nonmedullary, 1	Benign; Likely benign	rs34036248	RCV005921386

Show/Hide Text Mining Associations (11)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Breast Neoplasms	Associate	21278488
Carcinoma Hepatocellular	Associate	21383546
Carcinoma Renal Cell	Associate	37304236
Colonic Neoplasms	Stimulate	21383546
Glioblastoma	Associate	35295612
Liver Neoplasms	Associate	21383546
Neoplasms	Stimulate	21383546
Neoplasms	Associate	26949921, 33196683
Prostate Cancer Hereditary 7	Associate	33619025
Prostatic Neoplasms	Associate	33619025
Uveal melanoma	Associate	33196683

SLCO5A1 (solute carrier organic anion transporter family member 5A1)