Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	81706
Gene name	Protein phosphatase 1 regulatory inhibitor subunit 14C
Gene symbol	PPP1R14C
Synonyms (NCBI Gene)	CPI17-likeKEPINY-BR-81
Chromosome	6
Chromosome location	6q25.1
Summary	The degree of protein phosphorylation is regulated by a balance of protein kinase and phosphatase activities. Protein phosphatase-1 (PP1; see MIM 176875) is a signal-transducing phosphatase that influences neuronal activity, protein synthesis, metabolism,

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miRTarBase ID	miRNA	Experiments	Reference
MIRT019567	hsa-miR-340-5p	Sequencing	20371350
MIRT020380	hsa-miR-29c-3p	Sequencing	20371350
MIRT316374	hsa-miR-191-5p	PAR-CLIP	21572407
MIRT555354	hsa-miR-6757-3p	PAR-CLIP	21572407
MIRT316373	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT316377	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT316376	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT316379	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT316381	hsa-miR-3666	PAR-CLIP	21572407
MIRT316380	hsa-miR-4295	PAR-CLIP	21572407
MIRT316378	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT316383	hsa-miR-7114-5p	PAR-CLIP	21572407
MIRT316375	hsa-miR-134-3p	PAR-CLIP	21572407
MIRT555353	hsa-miR-6073	PAR-CLIP	21572407
MIRT555352	hsa-miR-142-3p	PAR-CLIP	21572407
MIRT316382	hsa-miR-4671-3p	PAR-CLIP	21572407
MIRT555351	hsa-miR-4743-3p	PAR-CLIP	21572407
MIRT555350	hsa-miR-4652-3p	PAR-CLIP	21572407
MIRT512986	hsa-miR-6768-5p	PAR-CLIP	22012620
MIRT512985	hsa-miR-302c-3p	PAR-CLIP	22012620
MIRT512984	hsa-miR-520f-3p	PAR-CLIP	22012620
MIRT512983	hsa-miR-128-3p	PAR-CLIP	22012620
MIRT512982	hsa-miR-216a-3p	PAR-CLIP	22012620
MIRT512981	hsa-miR-3681-3p	PAR-CLIP	22012620
MIRT512980	hsa-miR-6890-3p	PAR-CLIP	22012620
MIRT512979	hsa-miR-3166	PAR-CLIP	22012620
MIRT512978	hsa-miR-187-5p	PAR-CLIP	22012620
MIRT512977	hsa-miR-548v	PAR-CLIP	22012620
MIRT512976	hsa-miR-221-3p	PAR-CLIP	22012620
MIRT512975	hsa-miR-222-3p	PAR-CLIP	22012620
MIRT512974	hsa-miR-4672	PAR-CLIP	22012620
MIRT512973	hsa-miR-181b-2-3p	PAR-CLIP	22012620
MIRT512972	hsa-miR-181b-3p	PAR-CLIP	22012620
MIRT512971	hsa-miR-4420	PAR-CLIP	22012620
MIRT512970	hsa-miR-653-3p	PAR-CLIP	22012620
MIRT512969	hsa-miR-520b	PAR-CLIP	22012620
MIRT512968	hsa-miR-520c-3p	PAR-CLIP	22012620
MIRT512967	hsa-miR-520e	PAR-CLIP	22012620
MIRT512966	hsa-miR-526b-3p	PAR-CLIP	22012620
MIRT512986	hsa-miR-6768-5p	PAR-CLIP	23446348
MIRT512985	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT512984	hsa-miR-520f-3p	PAR-CLIP	23446348
MIRT512983	hsa-miR-128-3p	PAR-CLIP	23446348
MIRT512982	hsa-miR-216a-3p	PAR-CLIP	23446348
MIRT512981	hsa-miR-3681-3p	PAR-CLIP	23446348
MIRT512980	hsa-miR-6890-3p	PAR-CLIP	23446348
MIRT512979	hsa-miR-3166	PAR-CLIP	23446348
MIRT512978	hsa-miR-187-5p	PAR-CLIP	23446348
MIRT512977	hsa-miR-548v	PAR-CLIP	23446348
MIRT512976	hsa-miR-221-3p	PAR-CLIP	23446348
MIRT512975	hsa-miR-222-3p	PAR-CLIP	23446348
MIRT512974	hsa-miR-4672	PAR-CLIP	23446348
MIRT512973	hsa-miR-181b-2-3p	PAR-CLIP	23446348
MIRT512972	hsa-miR-181b-3p	PAR-CLIP	23446348
MIRT512971	hsa-miR-4420	PAR-CLIP	23446348
MIRT512970	hsa-miR-653-3p	PAR-CLIP	23446348
MIRT512969	hsa-miR-520b	PAR-CLIP	23446348
MIRT512968	hsa-miR-520c-3p	PAR-CLIP	23446348
MIRT512967	hsa-miR-520e	PAR-CLIP	23446348
MIRT512966	hsa-miR-526b-3p	PAR-CLIP	23446348
MIRT316374	hsa-miR-191-5p	PAR-CLIP	21572407
MIRT555354	hsa-miR-6757-3p	PAR-CLIP	21572407
MIRT316373	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT316377	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT316376	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT316379	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT316381	hsa-miR-3666	PAR-CLIP	21572407
MIRT316380	hsa-miR-4295	PAR-CLIP	21572407
MIRT316378	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT316383	hsa-miR-7114-5p	PAR-CLIP	21572407
MIRT316375	hsa-miR-134-3p	PAR-CLIP	21572407
MIRT555353	hsa-miR-6073	PAR-CLIP	21572407
MIRT555352	hsa-miR-142-3p	PAR-CLIP	21572407
MIRT316382	hsa-miR-4671-3p	PAR-CLIP	21572407
MIRT555351	hsa-miR-4743-3p	PAR-CLIP	21572407
MIRT555350	hsa-miR-4652-3p	PAR-CLIP	21572407
MIRT512986	hsa-miR-6768-5p	PAR-CLIP	22012620
MIRT512985	hsa-miR-302c-3p	PAR-CLIP	22012620
MIRT512984	hsa-miR-520f-3p	PAR-CLIP	22012620
MIRT512983	hsa-miR-128-3p	PAR-CLIP	22012620
MIRT512982	hsa-miR-216a-3p	PAR-CLIP	22012620
MIRT512981	hsa-miR-3681-3p	PAR-CLIP	22012620
MIRT512980	hsa-miR-6890-3p	PAR-CLIP	22012620
MIRT512979	hsa-miR-3166	PAR-CLIP	22012620
MIRT512978	hsa-miR-187-5p	PAR-CLIP	22012620
MIRT512977	hsa-miR-548v	PAR-CLIP	22012620
MIRT512976	hsa-miR-221-3p	PAR-CLIP	22012620
MIRT512975	hsa-miR-222-3p	PAR-CLIP	22012620
MIRT512974	hsa-miR-4672	PAR-CLIP	22012620
MIRT512973	hsa-miR-181b-2-3p	PAR-CLIP	22012620
MIRT512972	hsa-miR-181b-3p	PAR-CLIP	22012620
MIRT512971	hsa-miR-4420	PAR-CLIP	22012620
MIRT512970	hsa-miR-653-3p	PAR-CLIP	22012620
MIRT512969	hsa-miR-520b	PAR-CLIP	22012620
MIRT512968	hsa-miR-520c-3p	PAR-CLIP	22012620
MIRT512967	hsa-miR-520e	PAR-CLIP	22012620
MIRT512966	hsa-miR-526b-3p	PAR-CLIP	22012620
MIRT512986	hsa-miR-6768-5p	PAR-CLIP	23446348
MIRT512985	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT512984	hsa-miR-520f-3p	PAR-CLIP	23446348
MIRT512983	hsa-miR-128-3p	PAR-CLIP	23446348
MIRT512982	hsa-miR-216a-3p	PAR-CLIP	23446348
MIRT512981	hsa-miR-3681-3p	PAR-CLIP	23446348
MIRT512980	hsa-miR-6890-3p	PAR-CLIP	23446348
MIRT512979	hsa-miR-3166	PAR-CLIP	23446348
MIRT512978	hsa-miR-187-5p	PAR-CLIP	23446348
MIRT512977	hsa-miR-548v	PAR-CLIP	23446348
MIRT512976	hsa-miR-221-3p	PAR-CLIP	23446348
MIRT512975	hsa-miR-222-3p	PAR-CLIP	23446348
MIRT512974	hsa-miR-4672	PAR-CLIP	23446348
MIRT512973	hsa-miR-181b-2-3p	PAR-CLIP	23446348
MIRT512972	hsa-miR-181b-3p	PAR-CLIP	23446348
MIRT512971	hsa-miR-4420	PAR-CLIP	23446348
MIRT512970	hsa-miR-653-3p	PAR-CLIP	23446348
MIRT512969	hsa-miR-520b	PAR-CLIP	23446348
MIRT512968	hsa-miR-520c-3p	PAR-CLIP	23446348
MIRT512967	hsa-miR-520e	PAR-CLIP	23446348
MIRT512966	hsa-miR-526b-3p	PAR-CLIP	23446348
MIRT1255942	hsa-miR-142-5p	CLIP-seq
MIRT1255943	hsa-miR-2278	CLIP-seq
MIRT1255944	hsa-miR-512-5p	CLIP-seq
MIRT1255945	hsa-miR-9	CLIP-seq
MIRT2075441	hsa-miR-2115	CLIP-seq
MIRT2075442	hsa-miR-516a-3p	CLIP-seq
MIRT2075443	hsa-miR-520f	CLIP-seq
MIRT2302065	hsa-miR-128	CLIP-seq
MIRT2302066	hsa-miR-1296	CLIP-seq
MIRT2302067	hsa-miR-1912	CLIP-seq
MIRT2302068	hsa-miR-221	CLIP-seq
MIRT2302069	hsa-miR-222	CLIP-seq
MIRT2302070	hsa-miR-3143	CLIP-seq
MIRT2302071	hsa-miR-339-5p	CLIP-seq
MIRT2302072	hsa-miR-3663-3p	CLIP-seq
MIRT2302073	hsa-miR-4512	CLIP-seq
MIRT2302074	hsa-miR-4640-5p	CLIP-seq
MIRT2302075	hsa-miR-4726-5p	CLIP-seq
MIRT2302076	hsa-miR-487a	CLIP-seq
MIRT2302077	hsa-miR-543	CLIP-seq
MIRT2302078	hsa-miR-548ag	CLIP-seq
MIRT2302079	hsa-miR-548ai	CLIP-seq
MIRT2302080	hsa-miR-665	CLIP-seq
MIRT2302081	hsa-miR-670	CLIP-seq

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GO ID	Ontology	Definition	Evidence
GO:0004864	Function	Protein phosphatase inhibitor activity	IEA
GO:0004865	Function	Protein serine/threonine phosphatase inhibitor activity	IBA
GO:0004865	Function	Protein serine/threonine phosphatase inhibitor activity	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0016020	Component	Membrane	IEA
GO:0019212	Function	Phosphatase inhibitor activity	IEA
GO:0019888	Function	Protein phosphatase regulator activity	IEA

MIM	HGNC	e!Ensembl
613242	14952	ENSG00000198729

Q8TAE6

Protein name

Protein phosphatase 1 regulatory subunit 14C (Kinase-enhanced PP1 inhibitor) (PKC-potentiated PP1 inhibitory protein) (Serologically defined breast cancer antigen NY-BR-81)

Protein function

Inhibitor of the PP1 regulatory subunit PPP1CA.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF05361	PP1_inhibitor	39 → 165	PKC-activated protein phosphatase-1 inhibitor	Family

Tissue specificity

TISSUE SPECIFICITY: Detected in breast cancer. {ECO:0000269|PubMed:12747765}.

Sequence

MSVATGSSETAGGASGGGARVFFQSPRGGAGGSPGSSSGSGSSREDSAPVATAAAAGQVQ
QQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPEVEIDIDDLLDAD
SDEERASKLQEALVDCYKPTEEFIKELLSRIRGMRKLSPPQKKSV

Sequence length

165

Interactions

View interactions

PPP1R14C (protein phosphatase 1 regulatory inhibitor subunit 14C)