Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	81706
Gene name Gene Name - the full gene name approved by the HGNC.	Protein phosphatase 1 regulatory inhibitor subunit 14C
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PPP1R14C
Synonyms (NCBI Gene) Gene synonyms aliases	CPI17-like, KEPI, NY-BR-81
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6q25.1
Summary Summary of gene provided in NCBI Entrez Gene.	The degree of protein phosphorylation is regulated by a balance of protein kinase and phosphatase activities. Protein phosphatase-1 (PP1; see MIM 176875) is a signal-transducing phosphatase that influences neuronal activity, protein synthesis, metabolism,

Show/Hide all(142)

miRTarBase ID	miRNA	Experiments	Reference
MIRT019567	hsa-miR-340-5p	Sequencing	20371350
MIRT020380	hsa-miR-29c-3p	Sequencing	20371350
MIRT316374	hsa-miR-191-5p	PAR-CLIP	21572407
MIRT555354	hsa-miR-6757-3p	PAR-CLIP	21572407
MIRT316373	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT316377	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT316376	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT316379	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT316381	hsa-miR-3666	PAR-CLIP	21572407
MIRT316380	hsa-miR-4295	PAR-CLIP	21572407
MIRT316378	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT316383	hsa-miR-7114-5p	PAR-CLIP	21572407
MIRT316375	hsa-miR-134-3p	PAR-CLIP	21572407
MIRT555353	hsa-miR-6073	PAR-CLIP	21572407
MIRT555352	hsa-miR-142-3p	PAR-CLIP	21572407
MIRT316382	hsa-miR-4671-3p	PAR-CLIP	21572407
MIRT555351	hsa-miR-4743-3p	PAR-CLIP	21572407
MIRT555350	hsa-miR-4652-3p	PAR-CLIP	21572407
MIRT512986	hsa-miR-6768-5p	PAR-CLIP	22012620
MIRT512985	hsa-miR-302c-3p	PAR-CLIP	22012620
MIRT512984	hsa-miR-520f-3p	PAR-CLIP	22012620
MIRT512983	hsa-miR-128-3p	PAR-CLIP	22012620
MIRT512982	hsa-miR-216a-3p	PAR-CLIP	22012620
MIRT512981	hsa-miR-3681-3p	PAR-CLIP	22012620
MIRT512980	hsa-miR-6890-3p	PAR-CLIP	22012620
MIRT512979	hsa-miR-3166	PAR-CLIP	22012620
MIRT512978	hsa-miR-187-5p	PAR-CLIP	22012620
MIRT512977	hsa-miR-548v	PAR-CLIP	22012620
MIRT512976	hsa-miR-221-3p	PAR-CLIP	22012620
MIRT512975	hsa-miR-222-3p	PAR-CLIP	22012620
MIRT512974	hsa-miR-4672	PAR-CLIP	22012620
MIRT512973	hsa-miR-181b-2-3p	PAR-CLIP	22012620
MIRT512972	hsa-miR-181b-3p	PAR-CLIP	22012620
MIRT512971	hsa-miR-4420	PAR-CLIP	22012620
MIRT512970	hsa-miR-653-3p	PAR-CLIP	22012620
MIRT512969	hsa-miR-520b	PAR-CLIP	22012620
MIRT512968	hsa-miR-520c-3p	PAR-CLIP	22012620
MIRT512967	hsa-miR-520e	PAR-CLIP	22012620
MIRT512966	hsa-miR-526b-3p	PAR-CLIP	22012620
MIRT512986	hsa-miR-6768-5p	PAR-CLIP	23446348
MIRT512985	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT512984	hsa-miR-520f-3p	PAR-CLIP	23446348
MIRT512983	hsa-miR-128-3p	PAR-CLIP	23446348
MIRT512982	hsa-miR-216a-3p	PAR-CLIP	23446348
MIRT512981	hsa-miR-3681-3p	PAR-CLIP	23446348
MIRT512980	hsa-miR-6890-3p	PAR-CLIP	23446348
MIRT512979	hsa-miR-3166	PAR-CLIP	23446348
MIRT512978	hsa-miR-187-5p	PAR-CLIP	23446348
MIRT512977	hsa-miR-548v	PAR-CLIP	23446348
MIRT512976	hsa-miR-221-3p	PAR-CLIP	23446348
MIRT512975	hsa-miR-222-3p	PAR-CLIP	23446348
MIRT512974	hsa-miR-4672	PAR-CLIP	23446348
MIRT512973	hsa-miR-181b-2-3p	PAR-CLIP	23446348
MIRT512972	hsa-miR-181b-3p	PAR-CLIP	23446348
MIRT512971	hsa-miR-4420	PAR-CLIP	23446348
MIRT512970	hsa-miR-653-3p	PAR-CLIP	23446348
MIRT512969	hsa-miR-520b	PAR-CLIP	23446348
MIRT512968	hsa-miR-520c-3p	PAR-CLIP	23446348
MIRT512967	hsa-miR-520e	PAR-CLIP	23446348
MIRT512966	hsa-miR-526b-3p	PAR-CLIP	23446348
MIRT316374	hsa-miR-191-5p	PAR-CLIP	21572407
MIRT555354	hsa-miR-6757-3p	PAR-CLIP	21572407
MIRT316373	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT316377	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT316376	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT316379	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT316381	hsa-miR-3666	PAR-CLIP	21572407
MIRT316380	hsa-miR-4295	PAR-CLIP	21572407
MIRT316378	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT316383	hsa-miR-7114-5p	PAR-CLIP	21572407
MIRT316375	hsa-miR-134-3p	PAR-CLIP	21572407
MIRT555353	hsa-miR-6073	PAR-CLIP	21572407
MIRT555352	hsa-miR-142-3p	PAR-CLIP	21572407
MIRT316382	hsa-miR-4671-3p	PAR-CLIP	21572407
MIRT555351	hsa-miR-4743-3p	PAR-CLIP	21572407
MIRT555350	hsa-miR-4652-3p	PAR-CLIP	21572407
MIRT512986	hsa-miR-6768-5p	PAR-CLIP	22012620
MIRT512985	hsa-miR-302c-3p	PAR-CLIP	22012620
MIRT512984	hsa-miR-520f-3p	PAR-CLIP	22012620
MIRT512983	hsa-miR-128-3p	PAR-CLIP	22012620
MIRT512982	hsa-miR-216a-3p	PAR-CLIP	22012620
MIRT512981	hsa-miR-3681-3p	PAR-CLIP	22012620
MIRT512980	hsa-miR-6890-3p	PAR-CLIP	22012620
MIRT512979	hsa-miR-3166	PAR-CLIP	22012620
MIRT512978	hsa-miR-187-5p	PAR-CLIP	22012620
MIRT512977	hsa-miR-548v	PAR-CLIP	22012620
MIRT512976	hsa-miR-221-3p	PAR-CLIP	22012620
MIRT512975	hsa-miR-222-3p	PAR-CLIP	22012620
MIRT512974	hsa-miR-4672	PAR-CLIP	22012620
MIRT512973	hsa-miR-181b-2-3p	PAR-CLIP	22012620
MIRT512972	hsa-miR-181b-3p	PAR-CLIP	22012620
MIRT512971	hsa-miR-4420	PAR-CLIP	22012620
MIRT512970	hsa-miR-653-3p	PAR-CLIP	22012620
MIRT512969	hsa-miR-520b	PAR-CLIP	22012620
MIRT512968	hsa-miR-520c-3p	PAR-CLIP	22012620
MIRT512967	hsa-miR-520e	PAR-CLIP	22012620
MIRT512966	hsa-miR-526b-3p	PAR-CLIP	22012620
MIRT512986	hsa-miR-6768-5p	PAR-CLIP	23446348
MIRT512985	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT512984	hsa-miR-520f-3p	PAR-CLIP	23446348
MIRT512983	hsa-miR-128-3p	PAR-CLIP	23446348
MIRT512982	hsa-miR-216a-3p	PAR-CLIP	23446348
MIRT512981	hsa-miR-3681-3p	PAR-CLIP	23446348
MIRT512980	hsa-miR-6890-3p	PAR-CLIP	23446348
MIRT512979	hsa-miR-3166	PAR-CLIP	23446348
MIRT512978	hsa-miR-187-5p	PAR-CLIP	23446348
MIRT512977	hsa-miR-548v	PAR-CLIP	23446348
MIRT512976	hsa-miR-221-3p	PAR-CLIP	23446348
MIRT512975	hsa-miR-222-3p	PAR-CLIP	23446348
MIRT512974	hsa-miR-4672	PAR-CLIP	23446348
MIRT512973	hsa-miR-181b-2-3p	PAR-CLIP	23446348
MIRT512972	hsa-miR-181b-3p	PAR-CLIP	23446348
MIRT512971	hsa-miR-4420	PAR-CLIP	23446348
MIRT512970	hsa-miR-653-3p	PAR-CLIP	23446348
MIRT512969	hsa-miR-520b	PAR-CLIP	23446348
MIRT512968	hsa-miR-520c-3p	PAR-CLIP	23446348
MIRT512967	hsa-miR-520e	PAR-CLIP	23446348
MIRT512966	hsa-miR-526b-3p	PAR-CLIP	23446348
MIRT1255942	hsa-miR-142-5p	CLIP-seq
MIRT1255943	hsa-miR-2278	CLIP-seq
MIRT1255944	hsa-miR-512-5p	CLIP-seq
MIRT1255945	hsa-miR-9	CLIP-seq
MIRT2075441	hsa-miR-2115	CLIP-seq
MIRT2075442	hsa-miR-516a-3p	CLIP-seq
MIRT2075443	hsa-miR-520f	CLIP-seq
MIRT2302065	hsa-miR-128	CLIP-seq
MIRT2302066	hsa-miR-1296	CLIP-seq
MIRT2302067	hsa-miR-1912	CLIP-seq
MIRT2302068	hsa-miR-221	CLIP-seq
MIRT2302069	hsa-miR-222	CLIP-seq
MIRT2302070	hsa-miR-3143	CLIP-seq
MIRT2302071	hsa-miR-339-5p	CLIP-seq
MIRT2302072	hsa-miR-3663-3p	CLIP-seq
MIRT2302073	hsa-miR-4512	CLIP-seq
MIRT2302074	hsa-miR-4640-5p	CLIP-seq
MIRT2302075	hsa-miR-4726-5p	CLIP-seq
MIRT2302076	hsa-miR-487a	CLIP-seq
MIRT2302077	hsa-miR-543	CLIP-seq
MIRT2302078	hsa-miR-548ag	CLIP-seq
MIRT2302079	hsa-miR-548ai	CLIP-seq
MIRT2302080	hsa-miR-665	CLIP-seq
MIRT2302081	hsa-miR-670	CLIP-seq

Show/Hide all(5)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004865	Function	Protein serine/threonine phosphatase inhibitor activity	IBA	21873635
GO:0005737	Component	Cytoplasm	IEA
GO:0016020	Component	Membrane	IEA
GO:0032515	Process	Negative regulation of phosphoprotein phosphatase activity	IEA
GO:0042325	Process	Regulation of phosphorylation	IEA

MIM	HGNC	e!Ensembl
613242	14952	ENSG00000198729

Protein

UniProt ID

Q8TAE6

Protein name

Protein phosphatase 1 regulatory subunit 14C (Kinase-enhanced PP1 inhibitor) (PKC-potentiated PP1 inhibitory protein) (Serologically defined breast cancer antigen NY-BR-81)

Protein function

Inhibitor of the PP1 regulatory subunit PPP1CA.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF05361	PP1_inhibitor	39 → 165	PKC-activated protein phosphatase-1 inhibitor	Family

Tissue specificity

TISSUE SPECIFICITY: Detected in breast cancer. {ECO:0000269|PubMed:12747765}.

Sequence

MSVATGSSETAGGASGGGARVFFQSPRGGAGGSPGSSSGSGSSREDSAPVATAAAAGQVQ
QQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPEVEIDIDDLLDAD
SDEERASKLQEALVDCYKPTEEFIKELLSRIRGMRKLSPPQKKSV

Sequence length

165

Interactions

View interactions

Show/Hide Causal Diseases (3)

Disease term	Disease name	dbSNP ID	References
Causal
Endometrial carcinoma	Endometrial Carcinoma	rs34612342, rs587776667, rs587776701, rs63750955, rs587776706, rs121434629, rs80359605, rs121913530, rs104894365, rs79184941, rs121913478, rs63750781, rs193922343, rs267608094, rs267608077 View all (247 more)	30093612
Leukemia	Leukemia, Myelocytic, Acute	rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297	27903959
Myopathy	Myopathy	rs137854521, rs386834236, rs121908557, rs121909092, rs111033570, rs104894299, rs104894294, rs121909273, rs121909274, rs121909275, rs199474699, rs199476140, rs118192165, rs118192169, rs118192166 View all (81 more)	31220337

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Hyperopia	Hyperopia			GWAS

Show/Hide Text Mining Associations (3)

Disease Name	Relationship Type	References
Associations from Text Mining
Mucocutaneous Lymph Node Syndrome	Associate	19132087
Neoplasms	Inhibit	39174693
Squamous Cell Carcinoma of Head and Neck	Associate	39174693

PPP1R14C (protein phosphatase 1 regulatory inhibitor subunit 14C)