Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
81619
Gene name Gene Name - the full gene name approved by the HGNC.
Tetraspanin 14
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TSPAN14
Synonyms (NCBI Gene) Gene synonyms aliases
DC-TM4F2, TM4SF14, tspan-14
Chromosome Chromosome number
10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
10q23.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT020709 hsa-miR-155-5p Reporter assay;Other 20584899
MIRT025376 hsa-miR-34a-5p Sequencing 20371350
MIRT027896 hsa-miR-96-5p Sequencing 20371350
MIRT030452 hsa-miR-24-3p Microarray 19748357
MIRT039092 hsa-miR-769-3p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 23091066, 26686862
GO:0005788 Component Endoplasmic reticulum lumen TAS
GO:0005886 Component Plasma membrane IDA 23091066
GO:0005886 Component Plasma membrane TAS
GO:0005887 Component Integral component of plasma membrane IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein
UniProt ID Q8NG11
Protein name Tetraspanin-14 (Tspan-14) (DC-TM4F2) (Transmembrane 4 superfamily member 14)
Protein function Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell sur
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00335 Tetraspanin 15 260 Tetraspanin family Family
Sequence
Sequence length 270
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Neutrophil degranulation
Amyloid fiber formation
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Coronary artery disease Coronary Artery Disease rs137852988, rs121918313, rs121918529, rs121918531, rs137852340, rs1555800701, rs1215189537 29212778
Inflammatory bowel disease Inflammatory Bowel Diseases rs137853579, rs137853580, rs121909601, rs149491038, rs368287711, rs387907326, rs587777338, rs758439420, rs1329427406, rs1264862631, rs1192830343, rs1373354533, rs1419560997, rs1591263883, rs1989014468 28067908, 23128233, 26192919
Psoriasis Psoriasis rs281875215, rs587777763, rs281875213, rs281875212 26974007
Unknown
Disease term Disease name Evidence References Source
Chronic obstructive pulmonary disease Chronic Obstructive Airway Disease 30804561 ClinVar
Crohn disease Crohn Disease 26974007, 26192919, 28067908 ClinVar
Inflammatory Bowel Disease Inflammatory Bowel Disease GWAS
Metabolic Syndrome Metabolic Syndrome GWAS
Associations from Text Mining
Disease Name Relationship Type References
Alzheimer Disease Associate 36951251, 37735198
Breast Neoplasms Associate 34930307
Embolic Stroke Associate 35075378
Neoplasms Associate 34930307