TXNDC5 (thioredoxin domain containing 5)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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81567 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Thioredoxin domain containing 5 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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TXNDC5 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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ENDOPDI, ERP46, HCC-2, HCC2, PDIA15, STRF8, UNQ364 |
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Chromosome
Chromosome number
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6 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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6p24.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequ |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||
| UniProt ID | Q8NBS9 | ||||||||||||||||||||
| Protein name | Thioredoxin domain-containing protein 5 (EC 1.8.4.-) (EC 5.3.4.1) (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Thioredoxin-like protein p46) | ||||||||||||||||||||
| Protein function | Protein disulfide isomerase of the endoplasmic reticulum lumen involved in the formation of disulfide bonds in proteins. Can reduce insulin disulfide bonds. | ||||||||||||||||||||
| PDB | 2DIZ , 3UJ1 , 3UVT , 3WGD , 3WGE , 3WGX , 8EKY | ||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 432 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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