MAGED4B (MAGE family member D4B)

Gene

• Entrez ID: 81557
• Gene name: MAGE family member D4B
• Gene symbol: MAGED4B
• Synonyms (NCBI Gene): -
• Chromosome: X
• Chromosome location: Xp11.22
• Summary: This gene is a member of the MAGED gene family. It is expressed only in brain and ovary, and some transcript variants of this gene are specifically expressed in glioma cells. This gene is clustered with other MAGED genes on chromosome Xp11. Alternatively

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT017566	hsa-miR-335-5p	Microarray	18185580
MIRT440294	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440294	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT1125750	hsa-miR-4311	CLIP-seq
MIRT2565316	hsa-miR-1252	CLIP-seq
MIRT2565317	hsa-miR-149	CLIP-seq
MIRT2565318	hsa-miR-3064-5p	CLIP-seq
MIRT2565319	hsa-miR-3135	CLIP-seq
MIRT2565320	hsa-miR-3185	CLIP-seq
MIRT2565321	hsa-miR-3197	CLIP-seq
MIRT2565322	hsa-miR-3200-5p	CLIP-seq
MIRT2565323	hsa-miR-4251	CLIP-seq
MIRT2565324	hsa-miR-4329	CLIP-seq
MIRT2565325	hsa-miR-4695-5p	CLIP-seq
MIRT2565326	hsa-miR-4794	CLIP-seq
MIRT2565316	hsa-miR-1252	CLIP-seq
MIRT2565317	hsa-miR-149	CLIP-seq
MIRT2565318	hsa-miR-3064-5p	CLIP-seq
MIRT2565319	hsa-miR-3135	CLIP-seq
MIRT2565320	hsa-miR-3185	CLIP-seq
MIRT2565321	hsa-miR-3197	CLIP-seq
MIRT2565322	hsa-miR-3200-5p	CLIP-seq
MIRT2565323	hsa-miR-4251	CLIP-seq
MIRT2565324	hsa-miR-4329	CLIP-seq
MIRT2565325	hsa-miR-4695-5p	CLIP-seq
MIRT2565326	hsa-miR-4794	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IBA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IBA

Other IDs

• MIM: 300765
• HGNC: 22880
• e!Ensembl: ENSG00000187243

Interactions View interactions

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ARTERITIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Breast Neoplasms	Associate	30193086	★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Associate	22459352	★☆☆☆☆ Found in Text Mining only
Cholangiocarcinoma	Associate	26060332	★☆☆☆☆ Found in Text Mining only
Glioblastoma	Associate	35986882	★☆☆☆☆ Found in Text Mining only
Glioma	Associate	35986882	★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Associate	22459352	★☆☆☆☆ Found in Text Mining only
Mental Retardation X Linked	Associate	21668950	★☆☆☆☆ Found in Text Mining only
Mouth Neoplasms	Associate	25483651	★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	25483651, 30193086	★☆☆☆☆ Found in Text Mining only
Sarcoma	Associate	34307667	★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Associate	22459352, 25483651	★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Stimulate	30193086	★☆☆☆☆ Found in Text Mining only