Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	81532
Gene name Gene Name - the full gene name approved by the HGNC.	MOB kinase activator 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MOB2
Synonyms (NCBI Gene) Gene synonyms aliases	HCCA2
Chromosome Chromosome number	11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	11p15.5

Show/Hide all(94)

miRTarBase ID	miRNA	Experiments
MIRT1154173	hsa-miR-1228	CLIP-seq
MIRT1154174	hsa-miR-1245b-3p	CLIP-seq
MIRT1154175	hsa-miR-1827	CLIP-seq
MIRT1154176	hsa-miR-185	CLIP-seq
MIRT1154177	hsa-miR-214	CLIP-seq
MIRT1154178	hsa-miR-2276	CLIP-seq
MIRT1154179	hsa-miR-3179	CLIP-seq
MIRT1154180	hsa-miR-3202	CLIP-seq
MIRT1154181	hsa-miR-329	CLIP-seq
MIRT1154182	hsa-miR-3612	CLIP-seq
MIRT1154183	hsa-miR-3614-3p	CLIP-seq
MIRT1154184	hsa-miR-3619-5p	CLIP-seq
MIRT1154185	hsa-miR-3621	CLIP-seq
MIRT1154186	hsa-miR-362-3p	CLIP-seq
MIRT1154187	hsa-miR-3925-5p	CLIP-seq
MIRT1154188	hsa-miR-3936	CLIP-seq
MIRT1154189	hsa-miR-4297	CLIP-seq
MIRT1154190	hsa-miR-4306	CLIP-seq
MIRT1154191	hsa-miR-4476	CLIP-seq
MIRT1154192	hsa-miR-4644	CLIP-seq
MIRT1154193	hsa-miR-4695-5p	CLIP-seq
MIRT1154194	hsa-miR-4722-5p	CLIP-seq
MIRT1154195	hsa-miR-4768-3p	CLIP-seq
MIRT1154196	hsa-miR-4772-3p	CLIP-seq
MIRT1154197	hsa-miR-4802-5p	CLIP-seq
MIRT1154198	hsa-miR-548ag	CLIP-seq
MIRT1154199	hsa-miR-548ai	CLIP-seq
MIRT1154200	hsa-miR-556-3p	CLIP-seq
MIRT1154201	hsa-miR-572	CLIP-seq
MIRT1154202	hsa-miR-650	CLIP-seq
MIRT1154203	hsa-miR-761	CLIP-seq
MIRT1154204	hsa-miR-765	CLIP-seq
MIRT2044108	hsa-miR-3944-5p	CLIP-seq
MIRT2431226	hsa-miR-1304	CLIP-seq
MIRT2431227	hsa-miR-15a	CLIP-seq
MIRT2431228	hsa-miR-15b	CLIP-seq
MIRT2431229	hsa-miR-16	CLIP-seq
MIRT2431230	hsa-miR-195	CLIP-seq
MIRT2431231	hsa-miR-3065-3p	CLIP-seq
MIRT2431232	hsa-miR-424	CLIP-seq
MIRT2431233	hsa-miR-4419a	CLIP-seq
MIRT2431234	hsa-miR-4510	CLIP-seq
MIRT2431235	hsa-miR-4530	CLIP-seq
MIRT2431236	hsa-miR-497	CLIP-seq
MIRT1154175	hsa-miR-1827	CLIP-seq
MIRT1154177	hsa-miR-214	CLIP-seq
MIRT1154179	hsa-miR-3179	CLIP-seq
MIRT1154180	hsa-miR-3202	CLIP-seq
MIRT1154182	hsa-miR-3612	CLIP-seq
MIRT1154184	hsa-miR-3619-5p	CLIP-seq
MIRT1154188	hsa-miR-3936	CLIP-seq
MIRT1154191	hsa-miR-4476	CLIP-seq
MIRT1154193	hsa-miR-4695-5p	CLIP-seq
MIRT2438777	hsa-miR-542-3p	CLIP-seq
MIRT1154202	hsa-miR-650	CLIP-seq
MIRT1154203	hsa-miR-761	CLIP-seq
MIRT2572308	hsa-miR-1182	CLIP-seq
MIRT2572309	hsa-miR-1224-3p	CLIP-seq
MIRT1154173	hsa-miR-1228	CLIP-seq
MIRT2572310	hsa-miR-140-3p	CLIP-seq
MIRT2572311	hsa-miR-22	CLIP-seq
MIRT2572312	hsa-miR-3160-3p	CLIP-seq
MIRT2572313	hsa-miR-3173-3p	CLIP-seq
MIRT2572314	hsa-miR-361-3p	CLIP-seq
MIRT2572315	hsa-miR-3921	CLIP-seq
MIRT2572316	hsa-miR-4303	CLIP-seq
MIRT2572317	hsa-miR-4432	CLIP-seq
MIRT2572318	hsa-miR-4487	CLIP-seq
MIRT2572319	hsa-miR-4533	CLIP-seq
MIRT2572320	hsa-miR-4650-5p	CLIP-seq
MIRT2572321	hsa-miR-4653-5p	CLIP-seq
MIRT2572322	hsa-miR-4677-3p	CLIP-seq
MIRT2572323	hsa-miR-4679	CLIP-seq
MIRT2572324	hsa-miR-4747-5p	CLIP-seq
MIRT2572325	hsa-miR-4779	CLIP-seq
MIRT2572326	hsa-miR-558	CLIP-seq
MIRT2572327	hsa-miR-593	CLIP-seq
MIRT2572309	hsa-miR-1224-3p	CLIP-seq
MIRT1154173	hsa-miR-1228	CLIP-seq
MIRT2572310	hsa-miR-140-3p	CLIP-seq
MIRT2572311	hsa-miR-22	CLIP-seq
MIRT2572312	hsa-miR-3160-3p	CLIP-seq
MIRT2572313	hsa-miR-3173-3p	CLIP-seq
MIRT2572314	hsa-miR-361-3p	CLIP-seq
MIRT2572315	hsa-miR-3921	CLIP-seq
MIRT2572316	hsa-miR-4303	CLIP-seq
MIRT2572317	hsa-miR-4432	CLIP-seq
MIRT2572318	hsa-miR-4487	CLIP-seq
MIRT2572319	hsa-miR-4533	CLIP-seq
MIRT2572320	hsa-miR-4650-5p	CLIP-seq
MIRT2572321	hsa-miR-4653-5p	CLIP-seq
MIRT2572324	hsa-miR-4747-5p	CLIP-seq
MIRT2572325	hsa-miR-4779	CLIP-seq
MIRT2572326	hsa-miR-558	CLIP-seq

Show/Hide all(12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	24366813, 25852190, 28514442, 30108113, 32296183, 32707033, 33961781, 35271311
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005730	Component	Nucleolus	IDA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0007165	Process	Signal transduction	IBA
GO:0030295	Function	Protein kinase activator activity	IBA
GO:0046872	Function	Metal ion binding	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IEA

MIM	HGNC	e!Ensembl
611969	24904	ENSG00000182208

Protein

UniProt ID

Q70IA6

Protein name

MOB kinase activator 2 (HCCA2) (Mob2 homolog) (Mps one binder kinase activator-like 2)

Protein function

Stimulates the autophosphorylation and kinase activity of STK38 and STK38L.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03637	Mob1_phocein	32 → 200	Mob1/phocein family	Family

Sequence

MDWLMGKSKAKPNGKKPAAEERKAYLEPEHTKARITDFQFKELVVLPREIDLNEWLASNT
TTFFHHINLQYSTISEFCTGETCQTMAVCNTQYYWYDERGKKVKCTAPQYVDFVMSSVQK
LVTDEDVFPTKYGREFPSSFESLVRKICRHLFHVLAHIYWAHFKETLALELHGHLNTLYV
HFILFAREFNLLDPKETAIMDDLTEVLCSGAGGVHSGGSGDGAGSGGPGAQNHVKER

Sequence length

237

Interactions

View interactions

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Prostate cancer	Prostate cancer	N/A	N/A	GWAS

Show/Hide Text Mining Associations (6)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Carcinoma Hepatocellular	Associate	23326134
COVID 19	Associate	37643521
Diabetes Mellitus Type 2	Associate	23630301
Liver Neoplasms	Inhibit	23326134
Neoplasms	Associate	23326134
Ovarian Neoplasms	Associate	34363951

MOB2 (MOB kinase activator 2)