Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	81532
Gene name Gene Name - the full gene name approved by the HGNC.	MOB kinase activator 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MOB2
Synonyms (NCBI Gene) Gene synonyms aliases	HCCA2
Chromosome Chromosome number	11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	11p15.5

Show/Hide all(94)

miRTarBase ID	miRNA	Experiments
MIRT1154173	hsa-miR-1228	CLIP-seq
MIRT1154174	hsa-miR-1245b-3p	CLIP-seq
MIRT1154175	hsa-miR-1827	CLIP-seq
MIRT1154176	hsa-miR-185	CLIP-seq
MIRT1154177	hsa-miR-214	CLIP-seq
MIRT1154178	hsa-miR-2276	CLIP-seq
MIRT1154179	hsa-miR-3179	CLIP-seq
MIRT1154180	hsa-miR-3202	CLIP-seq
MIRT1154181	hsa-miR-329	CLIP-seq
MIRT1154182	hsa-miR-3612	CLIP-seq
MIRT1154183	hsa-miR-3614-3p	CLIP-seq
MIRT1154184	hsa-miR-3619-5p	CLIP-seq
MIRT1154185	hsa-miR-3621	CLIP-seq
MIRT1154186	hsa-miR-362-3p	CLIP-seq
MIRT1154187	hsa-miR-3925-5p	CLIP-seq
MIRT1154188	hsa-miR-3936	CLIP-seq
MIRT1154189	hsa-miR-4297	CLIP-seq
MIRT1154190	hsa-miR-4306	CLIP-seq
MIRT1154191	hsa-miR-4476	CLIP-seq
MIRT1154192	hsa-miR-4644	CLIP-seq
MIRT1154193	hsa-miR-4695-5p	CLIP-seq
MIRT1154194	hsa-miR-4722-5p	CLIP-seq
MIRT1154195	hsa-miR-4768-3p	CLIP-seq
MIRT1154196	hsa-miR-4772-3p	CLIP-seq
MIRT1154197	hsa-miR-4802-5p	CLIP-seq
MIRT1154198	hsa-miR-548ag	CLIP-seq
MIRT1154199	hsa-miR-548ai	CLIP-seq
MIRT1154200	hsa-miR-556-3p	CLIP-seq
MIRT1154201	hsa-miR-572	CLIP-seq
MIRT1154202	hsa-miR-650	CLIP-seq
MIRT1154203	hsa-miR-761	CLIP-seq
MIRT1154204	hsa-miR-765	CLIP-seq
MIRT2044108	hsa-miR-3944-5p	CLIP-seq
MIRT2431226	hsa-miR-1304	CLIP-seq
MIRT2431227	hsa-miR-15a	CLIP-seq
MIRT2431228	hsa-miR-15b	CLIP-seq
MIRT2431229	hsa-miR-16	CLIP-seq
MIRT2431230	hsa-miR-195	CLIP-seq
MIRT2431231	hsa-miR-3065-3p	CLIP-seq
MIRT2431232	hsa-miR-424	CLIP-seq
MIRT2431233	hsa-miR-4419a	CLIP-seq
MIRT2431234	hsa-miR-4510	CLIP-seq
MIRT2431235	hsa-miR-4530	CLIP-seq
MIRT2431236	hsa-miR-497	CLIP-seq
MIRT1154175	hsa-miR-1827	CLIP-seq
MIRT1154177	hsa-miR-214	CLIP-seq
MIRT1154179	hsa-miR-3179	CLIP-seq
MIRT1154180	hsa-miR-3202	CLIP-seq
MIRT1154182	hsa-miR-3612	CLIP-seq
MIRT1154184	hsa-miR-3619-5p	CLIP-seq
MIRT1154188	hsa-miR-3936	CLIP-seq
MIRT1154191	hsa-miR-4476	CLIP-seq
MIRT1154193	hsa-miR-4695-5p	CLIP-seq
MIRT2438777	hsa-miR-542-3p	CLIP-seq
MIRT1154202	hsa-miR-650	CLIP-seq
MIRT1154203	hsa-miR-761	CLIP-seq
MIRT2572308	hsa-miR-1182	CLIP-seq
MIRT2572309	hsa-miR-1224-3p	CLIP-seq
MIRT1154173	hsa-miR-1228	CLIP-seq
MIRT2572310	hsa-miR-140-3p	CLIP-seq
MIRT2572311	hsa-miR-22	CLIP-seq
MIRT2572312	hsa-miR-3160-3p	CLIP-seq
MIRT2572313	hsa-miR-3173-3p	CLIP-seq
MIRT2572314	hsa-miR-361-3p	CLIP-seq
MIRT2572315	hsa-miR-3921	CLIP-seq
MIRT2572316	hsa-miR-4303	CLIP-seq
MIRT2572317	hsa-miR-4432	CLIP-seq
MIRT2572318	hsa-miR-4487	CLIP-seq
MIRT2572319	hsa-miR-4533	CLIP-seq
MIRT2572320	hsa-miR-4650-5p	CLIP-seq
MIRT2572321	hsa-miR-4653-5p	CLIP-seq
MIRT2572322	hsa-miR-4677-3p	CLIP-seq
MIRT2572323	hsa-miR-4679	CLIP-seq
MIRT2572324	hsa-miR-4747-5p	CLIP-seq
MIRT2572325	hsa-miR-4779	CLIP-seq
MIRT2572326	hsa-miR-558	CLIP-seq
MIRT2572327	hsa-miR-593	CLIP-seq
MIRT2572309	hsa-miR-1224-3p	CLIP-seq
MIRT1154173	hsa-miR-1228	CLIP-seq
MIRT2572310	hsa-miR-140-3p	CLIP-seq
MIRT2572311	hsa-miR-22	CLIP-seq
MIRT2572312	hsa-miR-3160-3p	CLIP-seq
MIRT2572313	hsa-miR-3173-3p	CLIP-seq
MIRT2572314	hsa-miR-361-3p	CLIP-seq
MIRT2572315	hsa-miR-3921	CLIP-seq
MIRT2572316	hsa-miR-4303	CLIP-seq
MIRT2572317	hsa-miR-4432	CLIP-seq
MIRT2572318	hsa-miR-4487	CLIP-seq
MIRT2572319	hsa-miR-4533	CLIP-seq
MIRT2572320	hsa-miR-4650-5p	CLIP-seq
MIRT2572321	hsa-miR-4653-5p	CLIP-seq
MIRT2572324	hsa-miR-4747-5p	CLIP-seq
MIRT2572325	hsa-miR-4779	CLIP-seq
MIRT2572326	hsa-miR-558	CLIP-seq

Show/Hide all(6)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	24366813, 25852190, 28514442, 30108113, 32296183
GO:0005654	Component	Nucleoplasm	IDA
GO:0005730	Component	Nucleolus	IDA
GO:0005829	Component	Cytosol	IDA
GO:0046872	Function	Metal ion binding	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IEA

MIM	HGNC	e!Ensembl
611969	24904	ENSG00000182208

Protein

UniProt ID

Q70IA6

Protein name

MOB kinase activator 2 (HCCA2) (Mob2 homolog) (Mps one binder kinase activator-like 2)

Protein function

Stimulates the autophosphorylation and kinase activity of STK38 and STK38L.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03637	Mob1_phocein	32 → 200	Mob1/phocein family	Family

Sequence

MDWLMGKSKAKPNGKKPAAEERKAYLEPEHTKARITDFQFKELVVLPREIDLNEWLASNT
TTFFHHINLQYSTISEFCTGETCQTMAVCNTQYYWYDERGKKVKCTAPQYVDFVMSSVQK
LVTDEDVFPTKYGREFPSSFESLVRKICRHLFHVLAHIYWAHFKETLALELHGHLNTLYV
HFILFAREFNLLDPKETAIMDDLTEVLCSGAGGVHSGGSGDGAGSGGPGAQNHVKER

Sequence length

237

Interactions

View interactions

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID	References
Causal
Prostate cancer	Prostate carcinoma, Prostate cancer, familial	rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582	29892016
Prostate cancer, hereditary	PROSTATE CANCER, HEREDITARY, 1	rs387906327, rs193929331, rs74315365, rs397516896, rs794729219, rs121913349, rs587782641, rs1114167673, rs1597371666, rs2073394466	29892016

Show/Hide Text Mining Associations (6)

Disease Name	Relationship Type	References
Associations from Text Mining
Carcinoma Hepatocellular	Associate	23326134
COVID 19	Associate	37643521
Diabetes Mellitus Type 2	Associate	23630301
Liver Neoplasms	Inhibit	23326134
Neoplasms	Associate	23326134
Ovarian Neoplasms	Associate	34363951

MOB2 (MOB kinase activator 2)