Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	81494
Gene name Gene Name - the full gene name approved by the HGNC.	Complement factor H related 5
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CFHR5
Synonyms (NCBI Gene) Gene synonyms aliases	CFHL5, CFHR5D, FHR-5, FHR5
Disease Acronyms (UniProt) Disease acronyms from UniProt database	CFHR5D
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1q31.3
Summary Summary of gene provided in NCBI Entrez Gene.	This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has

Show/Hide all(4)

SNP ID	Visualize variation	Clinical significance	Consequence
rs41299613	T>C	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, missense variant
rs368209619	A>-	Pathogenic	Coding sequence variant, frameshift variant
rs565457964	->A,AA	Uncertain-significance, conflicting-interpretations-of-pathogenicity, benign, likely-benign	Coding sequence variant, frameshift variant
rs751010317	C>A	Uncertain-significance, pathogenic	Coding sequence variant, stop gained

Show/Hide all(216)

miRTarBase ID	miRNA	Experiments	Reference
MIRT619366	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT631575	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT633597	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT633596	hsa-miR-4258	HITS-CLIP	23824327
MIRT631574	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT633595	hsa-miR-2116-3p	HITS-CLIP	23824327
MIRT619365	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619364	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619363	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT619362	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT619361	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT619360	hsa-miR-593-3p	HITS-CLIP	23824327
MIRT619359	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT619358	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT619357	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT619356	hsa-miR-6818-3p	HITS-CLIP	23824327
MIRT619355	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT619354	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT619353	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT619366	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT631575	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT633597	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT631574	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT633595	hsa-miR-2116-3p	HITS-CLIP	23824327
MIRT619365	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619364	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619363	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT619362	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT619361	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT619360	hsa-miR-593-3p	HITS-CLIP	23824327
MIRT619359	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT619358	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT619357	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT633594	hsa-miR-493-5p	HITS-CLIP	23824327
MIRT619356	hsa-miR-6818-3p	HITS-CLIP	23824327
MIRT619355	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT619354	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT619353	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT619366	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT619365	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619364	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619363	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT619362	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT619361	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT619360	hsa-miR-593-3p	HITS-CLIP	23824327
MIRT619359	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT619358	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT619357	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT619356	hsa-miR-6818-3p	HITS-CLIP	23824327
MIRT619355	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT619354	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT619353	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT619366	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT631575	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT633597	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT633596	hsa-miR-4258	HITS-CLIP	23824327
MIRT631574	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT633595	hsa-miR-2116-3p	HITS-CLIP	23824327
MIRT619365	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619364	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619363	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT619362	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT619361	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT619360	hsa-miR-593-3p	HITS-CLIP	23824327
MIRT619359	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT619358	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT619357	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT633594	hsa-miR-493-5p	HITS-CLIP	23824327
MIRT619356	hsa-miR-6818-3p	HITS-CLIP	23824327
MIRT619355	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT619354	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT619353	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT619366	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT631575	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT631574	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT619365	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619364	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619363	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT619362	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT619361	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT619360	hsa-miR-593-3p	HITS-CLIP	23824327
MIRT619359	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT619358	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT619357	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT619356	hsa-miR-6818-3p	HITS-CLIP	23824327
MIRT619355	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT619354	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT619353	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT619366	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT619365	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619364	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619363	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT619362	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT619361	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT619360	hsa-miR-593-3p	HITS-CLIP	23824327
MIRT619359	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT619358	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT619357	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT619356	hsa-miR-6818-3p	HITS-CLIP	23824327
MIRT619355	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT619354	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT619353	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT619366	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT631575	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT633597	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT633596	hsa-miR-4258	HITS-CLIP	23824327
MIRT631574	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT633595	hsa-miR-2116-3p	HITS-CLIP	23824327
MIRT619365	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619364	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619363	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT619362	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT619361	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT619360	hsa-miR-593-3p	HITS-CLIP	23824327
MIRT619359	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT619358	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT619357	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT619356	hsa-miR-6818-3p	HITS-CLIP	23824327
MIRT619355	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT619354	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT619353	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT619366	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT631575	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT633597	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT631574	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT633595	hsa-miR-2116-3p	HITS-CLIP	23824327
MIRT619365	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619364	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619363	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT619362	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT619361	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT619360	hsa-miR-593-3p	HITS-CLIP	23824327
MIRT619359	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT619358	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT619357	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT633594	hsa-miR-493-5p	HITS-CLIP	23824327
MIRT619356	hsa-miR-6818-3p	HITS-CLIP	23824327
MIRT619355	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT619354	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT619353	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT619366	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT619365	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619364	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619363	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT619362	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT619361	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT619360	hsa-miR-593-3p	HITS-CLIP	23824327
MIRT619359	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT619358	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT619357	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT619356	hsa-miR-6818-3p	HITS-CLIP	23824327
MIRT619355	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT619354	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT619353	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT619366	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT631575	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT633597	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT633596	hsa-miR-4258	HITS-CLIP	23824327
MIRT631574	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT633595	hsa-miR-2116-3p	HITS-CLIP	23824327
MIRT619365	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619364	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619363	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT619362	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT619361	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT619360	hsa-miR-593-3p	HITS-CLIP	23824327
MIRT619359	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT619358	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT619357	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT633594	hsa-miR-493-5p	HITS-CLIP	23824327
MIRT619356	hsa-miR-6818-3p	HITS-CLIP	23824327
MIRT619355	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT619354	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT619353	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT619366	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT631575	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT631574	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT619365	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619364	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619363	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT619362	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT619361	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT619360	hsa-miR-593-3p	HITS-CLIP	23824327
MIRT619359	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT619358	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT619357	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT619356	hsa-miR-6818-3p	HITS-CLIP	23824327
MIRT619355	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT619354	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT619353	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT619366	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT619365	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619364	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619363	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT619362	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT619361	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT619360	hsa-miR-593-3p	HITS-CLIP	23824327
MIRT619359	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT619358	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT619357	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT619356	hsa-miR-6818-3p	HITS-CLIP	23824327
MIRT619355	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT619354	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT619353	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT887424	hsa-miR-200b	CLIP-seq
MIRT887425	hsa-miR-200c	CLIP-seq
MIRT887426	hsa-miR-2054	CLIP-seq
MIRT887427	hsa-miR-221	CLIP-seq
MIRT887428	hsa-miR-222	CLIP-seq
MIRT887429	hsa-miR-3617	CLIP-seq
MIRT887430	hsa-miR-429	CLIP-seq
MIRT887431	hsa-miR-4517	CLIP-seq
MIRT887432	hsa-miR-4667-3p	CLIP-seq
MIRT887433	hsa-miR-548v	CLIP-seq
MIRT887434	hsa-miR-641	CLIP-seq
MIRT2199592	hsa-miR-4699-5p	CLIP-seq

Show/Hide all(10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	23487775, 23728178, 25910212, 32296183
GO:0005576	Component	Extracellular region	NAS	11058592
GO:0005576	Component	Extracellular region	TAS
GO:0006957	Process	Complement activation, alternative pathway	NAS	11058592
GO:0030449	Process	Regulation of complement activation	TAS
GO:0032091	Process	Negative regulation of protein binding	IDA	23487775
GO:0032991	Component	Protein-containing complex	IMP	23487775
GO:0042802	Function	Identical protein binding	IPI	23487775
GO:0046982	Function	Protein heterodimerization activity	IDA	23487775
GO:0051838	Process	Cytolysis by host of symbiont cells	IMP	23487775

MIM	HGNC	e!Ensembl
608593	24668	ENSG00000134389

Protein

UniProt ID

Q9BXR6

Protein name

Complement factor H-related protein 5 (FHR-5)

Protein function

Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00084	Sushi	23 → 83	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	87 → 140	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	147 → 201	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	208 → 262	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	269 → 322	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	389 → 442	Sushi repeat (SCR repeat)	Domain
PF00084	Sushi	449 → 503	Sushi repeat (SCR repeat)	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed by the liver and secreted in plasma.

Sequence

MLLLFSVILISWVSTVGGEGTLCDFPKIHHGFLYDEEDYNPFSQVPTGEVFYYSCEYNFV
SPSKSFWTRITCTEEGWSPTPKCLRMCSFPFVKNGHSESSGLIHLEGDTVQIICNTGYSL
QNNEKNISCVERGWSTPPICSFTKGECHVPILEANVDAQPKKESYKVGDVLKFSCRKNLI
RVGSDSVQCYQFGWSPNFPTCKGQVRSCGPPPQLSNGEVKEIRKEEYGHNEVVEYDCNPN
FIINGPKKIQCVDGEWTTLPTCVEQVKTCGYIPELEYGYVQPSVPPYQHGVSVEVNCRNE
YAMIGNNMITCINGIWTELPMCVATHQLKRCKIAGVNIKTLLKLSGKEFNHNSRIRYRCS
DIFRYRHSVCINGKWNPEVDCTEKREQFCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKEN
YLLPEAKEIVCKDGRWQSLPRCVESTAYCGPPPSINNGDTTSFPLSVYPPGSTVTYRCQS
FYKLQGSVTVTCRNKQWSEPPRCLDPCVVSEENMNKNNIQLKWRNDGKLYAKTGDAVEFQ
CKFPHKAMISSPPFRAICQEGKFEYPICE

Sequence length

569

Interactions

View interactions

	KEGG		Reactome
	Complement and coagulation cascades		Regulation of Complement cascade

Show/Hide Causal Diseases (7)

Disease term	Disease name	dbSNP ID	References
Causal
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158 View all (309 more)
Cholestasis	Cholestasis	rs121909103, rs751511532, rs376368459, rs762702807, rs1578490102, rs1578499691, rs1578504946, rs1317656688, rs199791850, rs1452792080, rs1578491039	27989131
Complement component deficiency	Complement deficiency disease	rs387906509, rs1467298230, rs1022194067, rs774370086, rs121964922, rs372345940, rs121913052, rs121913053, rs460897, rs121913054, rs121913056, rs121913058, rs796052138, rs41286844, rs121909592 View all (29 more)	28673452
Glomerulonephritis	Glomerulonephritis	rs778043831
Hemolytic uremic syndrome	Atypical hemolytic uremic syndrome with anti-factor H antibodies	rs398124292, rs121964913, rs33972593, rs460897, rs121909590, rs121909583, rs460184, rs104886189, rs312262697, rs312262698, rs312262696, rs138924661, rs869312973, rs886039869, rs886039868 View all (24 more)
Kidney disease	Chronic kidney disease stage 5	rs74315342, rs749740335, rs757649673, rs112417755, rs35138315
Age-related macular degeneration	Age related macular degeneration	rs199474657, rs61750120, rs1800728, rs62654397, rs61749423, rs61751412, rs61749439, rs61751398, rs61752417, rs62645946, rs1801269, rs62646860, rs61750142, rs61750145, rs61750152 View all (20 more)	23326517, 20861866, 26691988, 23577725

Show/Hide Unknown Diseases (2)

Disease term	Disease name	References	Source
Unknown
C3 glomerulopathy	CFHR5 DEFICIENCY, C3 glomerulopathy	23026947, 22622361, 20800271, 28673452, 27458560, 22503529, 23402027, 24067434	ClinVar
Asthma	Asthma		GWAS

Show/Hide Text Mining Associations (36)

Disease Name	Relationship Type	References
Associations from Text Mining
Asthma	Associate	30366082
Ataxia Telangiectasia	Associate	28729648
Atypical Hemolytic Uremic Syndrome	Associate	22622361, 36793547
Calcinosis	Associate	35398599
Choroidal Neovascularization	Associate	23523162
Chronic Kidney Disease Mineral and Bone Disorder	Associate	40414211
Collagen Diseases	Associate	32879092
Complement Component 3 Deficiency Autosomal Recessive	Associate	21114651, 28729648
Complement Factor H Deficiency	Associate	21566112, 24067434, 26432903, 28729035, 29483359, 34566977, 37916369
Complement Factor I Deficiency	Associate	21566112
Dowling Degos Disease	Associate	16299065
Familial renal cell carcinoma	Associate	20800271
Glomerulonephritis	Associate	20800271, 29483359
Glomerulonephritis IGA	Associate	21566112, 25205734, 26825529, 28673452
Glomerulonephritis IGA	Stimulate	29759419
Glomerulonephritis Membranoproliferative	Associate	16299065, 24334459, 25855355, 28729648, 34566977
Glomerulonephritis With Isolated C3 Deposits And Factor I Deficiency	Associate	24067434, 27490940, 34238373
Glycogen Storage Disease Type II	Associate	30366082
Hematuria	Associate	40414211
Hemolytic Uremic Syndrome	Associate	25855355
Hyperplasia	Associate	32879092
Hypertension	Inhibit	29759419
Hypertension Pregnancy Induced	Stimulate	33874952
Immunologic Deficiency Syndromes	Associate	23728178, 25205734
Kidney Diseases	Associate	21114651, 24067434, 25855355, 26825529, 28729648, 34566977, 37916369, 40414211
Kidney Failure Chronic	Associate	21566112, 29759419
Lupus Erythematosus Systemic	Associate	21637784, 30485348, 30975435, 35398599
Lupus Nephritis	Stimulate	30975435
Lymphoma Follicular	Associate	22718493
Macular Degeneration	Associate	18541031, 19365580, 27647805, 29410599, 33273512, 34260947, 34260948, 34563268, 35113155, 40593839
Necrosis	Associate	29483359
Nephritis Hereditary	Associate	21566112
Polycystic Ovary Syndrome	Associate	36293087
Proteinuria	Associate	21566112, 30975435, 40414211
Renal Insufficiency Chronic	Associate	22503529
Respiratory Tract Diseases	Associate	32780727

CFHR5 (complement factor H related 5)