SYNC (syncoilin, intermediate filament protein)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 81493 |
| Gene name | Syncoilin, intermediate filament protein |
| Gene symbol | SYNC |
| Synonyms (NCBI Gene) |
SYNC1SYNCOILIN
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| Chromosome | 1 |
| Chromosome location | 1p35.1 |
| Summary | This gene encodes a member of the intermediate filament family which contains an N-terminal head domain, followed by a central coiled-coil region and a short C-terminal tail. The protein is highly expressed in skeletal and cardiac muscle. The protein link |
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miRNA
miRNA information provided by mirtarbase database.
465
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
14
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9H7C4 | ||||||||||
| Protein name | Syncoilin (Syncoilin intermediate filament 1) (Syncoilin-1) | ||||||||||
| Protein function | Atypical type III intermediate filament (IF) protein that may play a supportive role in the efficient coupling of mechanical stress between the myofibril and fiber exterior. May facilitate lateral force transmission during skeletal muscle contra | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 482 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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