GPR63 (G protein-coupled receptor 63)

Gene

• Entrez ID: 81491
• Gene name: G protein-coupled receptor 63
• Gene symbol: GPR63
• Synonyms (NCBI Gene): PSP24(beta), PSP24B
• Chromosome: 6
• Chromosome location: 6q16.1
• Summary: This gene encodes a G protein-coupled receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT025588	hsa-miR-10a-5p	Sequencing	20371350
MIRT030295	hsa-miR-26b-5p	Microarray	19088304
MIRT032107	hsa-let-7d-5p	Sequencing	20371350
MIRT448003	hsa-miR-1264	PAR-CLIP	22100165
MIRT448001	hsa-miR-520a-5p	PAR-CLIP	22100165
MIRT448000	hsa-miR-525-5p	PAR-CLIP	22100165
MIRT447998	hsa-miR-3161	PAR-CLIP	22100165
MIRT447999	hsa-miR-3180-5p	PAR-CLIP	22100165
MIRT447997	hsa-miR-599	PAR-CLIP	22100165
MIRT448003	hsa-miR-1264	PAR-CLIP	22100165
MIRT448001	hsa-miR-520a-5p	PAR-CLIP	22100165
MIRT448000	hsa-miR-525-5p	PAR-CLIP	22100165
MIRT447998	hsa-miR-3161	PAR-CLIP	22100165
MIRT447999	hsa-miR-3180-5p	PAR-CLIP	22100165
MIRT447997	hsa-miR-599	PAR-CLIP	22100165
MIRT448003	hsa-miR-1264	PAR-CLIP	22100165
MIRT448001	hsa-miR-520a-5p	PAR-CLIP	22100165
MIRT448000	hsa-miR-525-5p	PAR-CLIP	22100165
MIRT447998	hsa-miR-3161	PAR-CLIP	22100165
MIRT447999	hsa-miR-3180-5p	PAR-CLIP	22100165
MIRT447997	hsa-miR-599	PAR-CLIP	22100165
MIRT448003	hsa-miR-1264	PAR-CLIP	22100165
MIRT448001	hsa-miR-520a-5p	PAR-CLIP	22100165
MIRT448000	hsa-miR-525-5p	PAR-CLIP	22100165
MIRT447998	hsa-miR-3161	PAR-CLIP	22100165
MIRT447999	hsa-miR-3180-5p	PAR-CLIP	22100165
MIRT447997	hsa-miR-599	PAR-CLIP	22100165
MIRT1031609	hsa-miR-1260	CLIP-seq
MIRT1031610	hsa-miR-1260b	CLIP-seq
MIRT1031611	hsa-miR-188-3p	CLIP-seq
MIRT1031612	hsa-miR-3156-3p	CLIP-seq
MIRT1031613	hsa-miR-4301	CLIP-seq
MIRT2238559	hsa-miR-15a	CLIP-seq
MIRT2238560	hsa-miR-15b	CLIP-seq
MIRT2238561	hsa-miR-16	CLIP-seq
MIRT2238562	hsa-miR-195	CLIP-seq
MIRT2238563	hsa-miR-3671	CLIP-seq
MIRT2238564	hsa-miR-377	CLIP-seq
MIRT2238565	hsa-miR-424	CLIP-seq
MIRT2238566	hsa-miR-4524	CLIP-seq
MIRT2238567	hsa-miR-4789-3p	CLIP-seq
MIRT2238568	hsa-miR-497	CLIP-seq
MIRT2238569	hsa-miR-503	CLIP-seq
MIRT2238570	hsa-miR-646	CLIP-seq
MIRT2450653	hsa-miR-1205	CLIP-seq
MIRT2450654	hsa-miR-3155	CLIP-seq
MIRT2450655	hsa-miR-3155b	CLIP-seq
MIRT2450656	hsa-miR-4418	CLIP-seq
MIRT2450657	hsa-miR-4422	CLIP-seq
MIRT2450658	hsa-miR-484	CLIP-seq
MIRT2450659	hsa-miR-509-3-5p	CLIP-seq
MIRT2450660	hsa-miR-509-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004930	Function	G protein-coupled receptor activity	IBA
GO:0004930	Function	G protein-coupled receptor activity	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005829	Component	Cytosol	IDA
GO:0005886	Component	Plasma membrane	IDA
GO:0005886	Component	Plasma membrane	IEA
GO:0007165	Process	Signal transduction	IEA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IBA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IEA
GO:0016020	Component	Membrane	IEA
GO:0043235	Component	Receptor complex	IDA	23382219

Other IDs

• MIM: 606915
• HGNC: 13302
• e!Ensembl: ENSG00000112218

Protein

• UniProt ID: Q9BZJ6
• Protein name: Probable G-protein coupled receptor 63 (PSP24-2) (PSP24-beta)
• Protein function: Orphan receptor. May play a role in brain function.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00001	7tm_1	98 → 371	7 transmembrane receptor (rhodopsin family)	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed in brain; detected in the frontal cortex, with lower levels in the thalamus, caudate, hypothalamus and midbrain.
• Sequence:

  MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT
  VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL
  ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF
  LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ
  AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF
  QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC
  YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV

• Sequence length: 419