Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	81490
Gene name	Phosphatidylserine synthase 2
Gene symbol	PTDSS2
Synonyms (NCBI Gene)	PSS2
Chromosome	11
Chromosome location	11p15.5
Summary	The protein encoded by this gene catalyzes the conversion of phosphatidylethanolamine to phosphatidylserine, a structural membrane phospholipid that functions in cell signaling, blood coagulation, and apoptosis. The encoded enzyme also has a high affinity

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miRTarBase ID	miRNA	Experiments	Reference
MIRT046833	hsa-miR-222-3p	CLASH	23622248
MIRT041217	hsa-miR-193b-3p	CLASH	23622248
MIRT714460	hsa-miR-4695-5p	HITS-CLIP	19536157
MIRT714459	hsa-miR-4779	HITS-CLIP	19536157
MIRT633791	hsa-miR-3612	HITS-CLIP	19536157
MIRT633790	hsa-miR-650	HITS-CLIP	19536157
MIRT714455	hsa-miR-4266	HITS-CLIP	19536157
MIRT714460	hsa-miR-4695-5p	HITS-CLIP	19536157
MIRT714459	hsa-miR-4779	HITS-CLIP	19536157
MIRT633791	hsa-miR-3612	HITS-CLIP	19536157
MIRT633790	hsa-miR-650	HITS-CLIP	19536157
MIRT714455	hsa-miR-4266	HITS-CLIP	19536157
MIRT714460	hsa-miR-4695-5p	HITS-CLIP	19536157
MIRT714459	hsa-miR-4779	HITS-CLIP	19536157
MIRT714458	hsa-miR-1910-3p	HITS-CLIP	19536157
MIRT714457	hsa-miR-6511a-5p	HITS-CLIP	19536157
MIRT714456	hsa-miR-1827	HITS-CLIP	19536157
MIRT633791	hsa-miR-3612	HITS-CLIP	19536157
MIRT633790	hsa-miR-650	HITS-CLIP	19536157
MIRT714455	hsa-miR-4266	HITS-CLIP	19536157
MIRT695058	hsa-miR-548n	HITS-CLIP	23313552
MIRT695057	hsa-miR-548az-5p	HITS-CLIP	23313552
MIRT695056	hsa-miR-548t-5p	HITS-CLIP	23313552
MIRT695055	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT670715	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT670714	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT631813	hsa-miR-4486	HITS-CLIP	23824327
MIRT631809	hsa-miR-4284	HITS-CLIP	23824327
MIRT670713	hsa-miR-3652	HITS-CLIP	23824327
MIRT670712	hsa-miR-4430	HITS-CLIP	23824327
MIRT631808	hsa-miR-4505	HITS-CLIP	23824327
MIRT631807	hsa-miR-5787	HITS-CLIP	23824327
MIRT631806	hsa-miR-3178	HITS-CLIP	23824327
MIRT629776	hsa-miR-7977	HITS-CLIP	23824327
MIRT670711	hsa-miR-425-3p	HITS-CLIP	23824327
MIRT670710	hsa-miR-6771-5p	HITS-CLIP	23824327
MIRT670709	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT631799	hsa-miR-4508	HITS-CLIP	23824327
MIRT670715	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT670714	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT670713	hsa-miR-3652	HITS-CLIP	23824327
MIRT670712	hsa-miR-4430	HITS-CLIP	23824327
MIRT629776	hsa-miR-7977	HITS-CLIP	23824327
MIRT670711	hsa-miR-425-3p	HITS-CLIP	23824327
MIRT670710	hsa-miR-6771-5p	HITS-CLIP	23824327
MIRT670709	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT631799	hsa-miR-4508	HITS-CLIP	23824327
MIRT629786	hsa-miR-1321	HITS-CLIP	23824327
MIRT629785	hsa-miR-4739	HITS-CLIP	23824327
MIRT629784	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT631818	hsa-miR-4267	HITS-CLIP	23824327
MIRT629779	hsa-miR-3664-3p	HITS-CLIP	23824327
MIRT629778	hsa-miR-1266-5p	HITS-CLIP	23824327
MIRT629777	hsa-miR-4518	HITS-CLIP	23824327
MIRT629776	hsa-miR-7977	HITS-CLIP	23824327
MIRT629786	hsa-miR-1321	HITS-CLIP	23824327
MIRT629785	hsa-miR-4739	HITS-CLIP	23824327
MIRT629784	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT631818	hsa-miR-4267	HITS-CLIP	23824327
MIRT629779	hsa-miR-3664-3p	HITS-CLIP	23824327
MIRT648113	hsa-miR-3622b-5p	HITS-CLIP	23824327
MIRT648112	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT648111	hsa-miR-4253	HITS-CLIP	23824327
MIRT648110	hsa-miR-6862-5p	HITS-CLIP	23824327
MIRT629786	hsa-miR-1321	HITS-CLIP	23824327
MIRT629785	hsa-miR-4739	HITS-CLIP	23824327
MIRT629784	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT629783	hsa-miR-211-3p	HITS-CLIP	23824327
MIRT629782	hsa-miR-4270	HITS-CLIP	23824327
MIRT629781	hsa-miR-4441	HITS-CLIP	23824327
MIRT629780	hsa-miR-6754-5p	HITS-CLIP	23824327
MIRT629779	hsa-miR-3664-3p	HITS-CLIP	23824327
MIRT629778	hsa-miR-1266-5p	HITS-CLIP	23824327
MIRT629777	hsa-miR-4518	HITS-CLIP	23824327
MIRT629786	hsa-miR-1321	HITS-CLIP	23824327
MIRT629785	hsa-miR-4739	HITS-CLIP	23824327
MIRT629784	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT629783	hsa-miR-211-3p	HITS-CLIP	23824327
MIRT629782	hsa-miR-4270	HITS-CLIP	23824327
MIRT629781	hsa-miR-4441	HITS-CLIP	23824327
MIRT629780	hsa-miR-6754-5p	HITS-CLIP	23824327
MIRT629779	hsa-miR-3664-3p	HITS-CLIP	23824327
MIRT629778	hsa-miR-1266-5p	HITS-CLIP	23824327
MIRT629777	hsa-miR-4518	HITS-CLIP	23824327
MIRT633791	hsa-miR-3612	HITS-CLIP	23824327
MIRT633790	hsa-miR-650	HITS-CLIP	23824327
MIRT629786	hsa-miR-1321	HITS-CLIP	23824327
MIRT629785	hsa-miR-4739	HITS-CLIP	23824327
MIRT629784	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT631818	hsa-miR-4267	HITS-CLIP	23824327
MIRT629779	hsa-miR-3664-3p	HITS-CLIP	23824327
MIRT631817	hsa-miR-6085	HITS-CLIP	23824327
MIRT631816	hsa-miR-6813-5p	HITS-CLIP	23824327
MIRT631815	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT631814	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT631813	hsa-miR-4486	HITS-CLIP	23824327
MIRT631812	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT631810	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT631811	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT631809	hsa-miR-4284	HITS-CLIP	23824327
MIRT631808	hsa-miR-4505	HITS-CLIP	23824327
MIRT631807	hsa-miR-5787	HITS-CLIP	23824327
MIRT631806	hsa-miR-3178	HITS-CLIP	23824327
MIRT631805	hsa-miR-4492	HITS-CLIP	23824327
MIRT631804	hsa-miR-4498	HITS-CLIP	23824327
MIRT631803	hsa-miR-5001-5p	HITS-CLIP	23824327
MIRT631802	hsa-miR-762	HITS-CLIP	23824327
MIRT631801	hsa-miR-185-3p	HITS-CLIP	23824327
MIRT629776	hsa-miR-7977	HITS-CLIP	23824327
MIRT631800	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT631799	hsa-miR-4508	HITS-CLIP	23824327
MIRT629786	hsa-miR-1321	HITS-CLIP	23824327
MIRT629785	hsa-miR-4739	HITS-CLIP	23824327
MIRT629784	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT629783	hsa-miR-211-3p	HITS-CLIP	23824327
MIRT629782	hsa-miR-4270	HITS-CLIP	23824327
MIRT629781	hsa-miR-4441	HITS-CLIP	23824327
MIRT629780	hsa-miR-6754-5p	HITS-CLIP	23824327
MIRT629779	hsa-miR-3664-3p	HITS-CLIP	23824327
MIRT629778	hsa-miR-1266-5p	HITS-CLIP	23824327
MIRT629777	hsa-miR-4518	HITS-CLIP	23824327
MIRT629776	hsa-miR-7977	HITS-CLIP	23824327
MIRT633791	hsa-miR-3612	PAR-CLIP	27292025
MIRT714455	hsa-miR-4266	PAR-CLIP	27292025
MIRT714460	hsa-miR-4695-5p	PAR-CLIP	27292025
MIRT714459	hsa-miR-4779	PAR-CLIP	27292025
MIRT633790	hsa-miR-650	PAR-CLIP	27292025
MIRT714460	hsa-miR-4695-5p	HITS-CLIP	19536157
MIRT714459	hsa-miR-4779	HITS-CLIP	19536157
MIRT633791	hsa-miR-3612	HITS-CLIP	19536157
MIRT633790	hsa-miR-650	HITS-CLIP	19536157
MIRT714455	hsa-miR-4266	HITS-CLIP	19536157
MIRT714460	hsa-miR-4695-5p	HITS-CLIP	19536157
MIRT714459	hsa-miR-4779	HITS-CLIP	19536157
MIRT633791	hsa-miR-3612	HITS-CLIP	19536157
MIRT633790	hsa-miR-650	HITS-CLIP	19536157
MIRT714455	hsa-miR-4266	HITS-CLIP	19536157
MIRT714460	hsa-miR-4695-5p	HITS-CLIP	19536157
MIRT714459	hsa-miR-4779	HITS-CLIP	19536157
MIRT714458	hsa-miR-1910-3p	HITS-CLIP	19536157
MIRT714457	hsa-miR-6511a-5p	HITS-CLIP	19536157
MIRT714456	hsa-miR-1827	HITS-CLIP	19536157
MIRT633791	hsa-miR-3612	HITS-CLIP	19536157
MIRT633790	hsa-miR-650	HITS-CLIP	19536157
MIRT714455	hsa-miR-4266	HITS-CLIP	19536157
MIRT695058	hsa-miR-548n	HITS-CLIP	23313552
MIRT695057	hsa-miR-548az-5p	HITS-CLIP	23313552
MIRT695056	hsa-miR-548t-5p	HITS-CLIP	23313552
MIRT695055	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT670715	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT670714	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT631813	hsa-miR-4486	HITS-CLIP	23824327
MIRT631809	hsa-miR-4284	HITS-CLIP	23824327
MIRT670713	hsa-miR-3652	HITS-CLIP	23824327
MIRT670712	hsa-miR-4430	HITS-CLIP	23824327
MIRT631808	hsa-miR-4505	HITS-CLIP	23824327
MIRT631807	hsa-miR-5787	HITS-CLIP	23824327
MIRT631806	hsa-miR-3178	HITS-CLIP	23824327
MIRT629776	hsa-miR-7977	HITS-CLIP	23824327
MIRT670711	hsa-miR-425-3p	HITS-CLIP	23824327
MIRT670710	hsa-miR-6771-5p	HITS-CLIP	23824327
MIRT670709	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT631799	hsa-miR-4508	HITS-CLIP	23824327
MIRT670715	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT670714	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT670713	hsa-miR-3652	HITS-CLIP	23824327
MIRT670712	hsa-miR-4430	HITS-CLIP	23824327
MIRT629776	hsa-miR-7977	HITS-CLIP	23824327
MIRT670711	hsa-miR-425-3p	HITS-CLIP	23824327
MIRT670710	hsa-miR-6771-5p	HITS-CLIP	23824327
MIRT670709	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT631799	hsa-miR-4508	HITS-CLIP	23824327
MIRT629786	hsa-miR-1321	HITS-CLIP	23824327
MIRT629785	hsa-miR-4739	HITS-CLIP	23824327
MIRT629784	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT631818	hsa-miR-4267	HITS-CLIP	23824327
MIRT629779	hsa-miR-3664-3p	HITS-CLIP	23824327
MIRT629778	hsa-miR-1266-5p	HITS-CLIP	23824327
MIRT629777	hsa-miR-4518	HITS-CLIP	23824327
MIRT629776	hsa-miR-7977	HITS-CLIP	23824327
MIRT629786	hsa-miR-1321	HITS-CLIP	23824327
MIRT629785	hsa-miR-4739	HITS-CLIP	23824327
MIRT629784	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT631818	hsa-miR-4267	HITS-CLIP	23824327
MIRT629779	hsa-miR-3664-3p	HITS-CLIP	23824327
MIRT648113	hsa-miR-3622b-5p	HITS-CLIP	23824327
MIRT648112	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT648111	hsa-miR-4253	HITS-CLIP	23824327
MIRT648110	hsa-miR-6862-5p	HITS-CLIP	23824327
MIRT629786	hsa-miR-1321	HITS-CLIP	23824327
MIRT629785	hsa-miR-4739	HITS-CLIP	23824327
MIRT629784	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT629783	hsa-miR-211-3p	HITS-CLIP	23824327
MIRT629782	hsa-miR-4270	HITS-CLIP	23824327
MIRT629781	hsa-miR-4441	HITS-CLIP	23824327
MIRT629780	hsa-miR-6754-5p	HITS-CLIP	23824327
MIRT629779	hsa-miR-3664-3p	HITS-CLIP	23824327
MIRT629778	hsa-miR-1266-5p	HITS-CLIP	23824327
MIRT629777	hsa-miR-4518	HITS-CLIP	23824327
MIRT629786	hsa-miR-1321	HITS-CLIP	23824327
MIRT629785	hsa-miR-4739	HITS-CLIP	23824327
MIRT629784	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT629783	hsa-miR-211-3p	HITS-CLIP	23824327
MIRT629782	hsa-miR-4270	HITS-CLIP	23824327
MIRT629781	hsa-miR-4441	HITS-CLIP	23824327
MIRT629780	hsa-miR-6754-5p	HITS-CLIP	23824327
MIRT629779	hsa-miR-3664-3p	HITS-CLIP	23824327
MIRT629778	hsa-miR-1266-5p	HITS-CLIP	23824327
MIRT629777	hsa-miR-4518	HITS-CLIP	23824327
MIRT633791	hsa-miR-3612	HITS-CLIP	23824327
MIRT633790	hsa-miR-650	HITS-CLIP	23824327
MIRT629786	hsa-miR-1321	HITS-CLIP	23824327
MIRT629785	hsa-miR-4739	HITS-CLIP	23824327
MIRT629784	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT631818	hsa-miR-4267	HITS-CLIP	23824327
MIRT629779	hsa-miR-3664-3p	HITS-CLIP	23824327
MIRT631817	hsa-miR-6085	HITS-CLIP	23824327
MIRT631816	hsa-miR-6813-5p	HITS-CLIP	23824327
MIRT631815	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT631814	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT631813	hsa-miR-4486	HITS-CLIP	23824327
MIRT631812	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT631810	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT631811	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT631809	hsa-miR-4284	HITS-CLIP	23824327
MIRT631808	hsa-miR-4505	HITS-CLIP	23824327
MIRT631807	hsa-miR-5787	HITS-CLIP	23824327
MIRT631806	hsa-miR-3178	HITS-CLIP	23824327
MIRT631805	hsa-miR-4492	HITS-CLIP	23824327
MIRT631804	hsa-miR-4498	HITS-CLIP	23824327
MIRT631803	hsa-miR-5001-5p	HITS-CLIP	23824327
MIRT631802	hsa-miR-762	HITS-CLIP	23824327
MIRT631801	hsa-miR-185-3p	HITS-CLIP	23824327
MIRT629776	hsa-miR-7977	HITS-CLIP	23824327
MIRT631800	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT631799	hsa-miR-4508	HITS-CLIP	23824327
MIRT629786	hsa-miR-1321	HITS-CLIP	23824327
MIRT629785	hsa-miR-4739	HITS-CLIP	23824327
MIRT629784	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT629783	hsa-miR-211-3p	HITS-CLIP	23824327
MIRT629782	hsa-miR-4270	HITS-CLIP	23824327
MIRT629781	hsa-miR-4441	HITS-CLIP	23824327
MIRT629780	hsa-miR-6754-5p	HITS-CLIP	23824327
MIRT629779	hsa-miR-3664-3p	HITS-CLIP	23824327
MIRT629778	hsa-miR-1266-5p	HITS-CLIP	23824327
MIRT629777	hsa-miR-4518	HITS-CLIP	23824327
MIRT629776	hsa-miR-7977	HITS-CLIP	23824327
MIRT1272234	hsa-miR-103a	CLIP-seq
MIRT1272235	hsa-miR-107	CLIP-seq
MIRT1272236	hsa-miR-3689d	CLIP-seq
MIRT1272237	hsa-miR-432	CLIP-seq
MIRT1272238	hsa-miR-4434	CLIP-seq
MIRT1272239	hsa-miR-4476	CLIP-seq
MIRT1272240	hsa-miR-4516	CLIP-seq
MIRT1272241	hsa-miR-4531	CLIP-seq
MIRT1272242	hsa-miR-4725-5p	CLIP-seq
MIRT1272243	hsa-miR-488	CLIP-seq
MIRT1272244	hsa-miR-504	CLIP-seq
MIRT1272245	hsa-miR-516b	CLIP-seq
MIRT1272246	hsa-miR-765	CLIP-seq
MIRT1552666	hsa-miR-4514	CLIP-seq
MIRT1552667	hsa-miR-4645-5p	CLIP-seq
MIRT1552668	hsa-miR-4673	CLIP-seq
MIRT1552669	hsa-miR-4692	CLIP-seq
MIRT2080037	hsa-miR-2117	CLIP-seq
MIRT2080038	hsa-miR-4691-5p	CLIP-seq
MIRT2080039	hsa-miR-4731-5p	CLIP-seq
MIRT2080040	hsa-miR-4753-3p	CLIP-seq
MIRT2080041	hsa-miR-659	CLIP-seq
MIRT2080042	hsa-miR-668	CLIP-seq
MIRT2306356	hsa-miR-329	CLIP-seq
MIRT2306357	hsa-miR-362-3p	CLIP-seq
MIRT2306358	hsa-miR-3941	CLIP-seq
MIRT2306359	hsa-miR-603	CLIP-seq
MIRT2603659	hsa-miR-1293	CLIP-seq
MIRT2603660	hsa-miR-1913	CLIP-seq
MIRT2603661	hsa-miR-3064-3p	CLIP-seq
MIRT2603662	hsa-miR-3189-5p	CLIP-seq
MIRT2603663	hsa-miR-323-5p	CLIP-seq
MIRT2603664	hsa-miR-324-3p	CLIP-seq
MIRT2603665	hsa-miR-3909	CLIP-seq
MIRT1272239	hsa-miR-4476	CLIP-seq
MIRT2603666	hsa-miR-4483	CLIP-seq
MIRT2603667	hsa-miR-4527	CLIP-seq
MIRT2603668	hsa-miR-4651	CLIP-seq
MIRT2603669	hsa-miR-4715-3p	CLIP-seq
MIRT2603670	hsa-miR-4758-3p	CLIP-seq
MIRT1272243	hsa-miR-488	CLIP-seq
MIRT2306359	hsa-miR-603	CLIP-seq
MIRT2603671	hsa-miR-608	CLIP-seq
MIRT2603672	hsa-miR-661	CLIP-seq
MIRT1272246	hsa-miR-765	CLIP-seq
MIRT2603673	hsa-miR-938	CLIP-seq

Show/Hide all (17)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003882	Function	CDP-diacylglycerol-serine O-phosphatidyltransferase activity	IEA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	ISS
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006659	Process	Phosphatidylserine biosynthetic process	IDA	19014349
GO:0006659	Process	Phosphatidylserine biosynthetic process	IEA
GO:0006659	Process	Phosphatidylserine biosynthetic process	IEA
GO:0006659	Process	Phosphatidylserine biosynthetic process	TAS
GO:0008654	Process	Phospholipid biosynthetic process	IEA
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	ISS
GO:0016740	Function	Transferase activity	IEA
GO:0016740	Function	Transferase activity	TAS
GO:0106245	Function	L-serine-phosphatidylethanolamine phosphatidyltransferase activity	IDA	19014349
GO:0106245	Function	L-serine-phosphatidylethanolamine phosphatidyltransferase activity	IEA

MIM	HGNC	e!Ensembl
612793	15463	ENSG00000174915

Q9BVG9

Protein name

Phosphatidylserine synthase 2 (PSS-2) (PtdSer synthase 2) (EC 2.7.8.29) (Serine-exchange enzyme II)

Protein function

Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine (PubMed:19014349). Catalyzes the conversion of phosphatatidylethanolamine and does not act on p

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03034	PSS	120 → 400	Phosphatidyl serine synthase	Family

Sequence

MRRGERRDAGGPRPESPVPAGRASLEEPPDGPSAGQATGPGEGRRSTESEVYDDGTNTFF
WRAHTLTVLFILTCTLGYVTLLEETPQDTAYNTKRGIVASILVFLCFGVTQAKDGPFSRP
HPAYWRFWLCVSVVYELFLIFILFQTVQDGRQFLKYVDPKLGVPLPERDYGGNCLIYDPD
NETDPFHNIWDKLDGFVPAHFLGWYLKTLMIRDWWMCMIISVMFEFLEYSLEHQLPNFSE
CWWDHWIMDVLVCNGLGIYCGMKTLEWLSLKTYKWQGLWNIPTYKGKMKRIAFQFTPYSW
VRFEWKPASSLRRWLAVCGIILVFLLAELNTFYLKFVLWMPPEHYLVLLRLVFFVNVGGV
AMREIYDFMDDPKPHKKLGPQAWLVAAITATELLIVVKYDPHTLTLSLPFYISQCWTLGS
VLALTWTVWRFFLRDITLRYKETRWQKWQNKDDQGSTVGNGDQHPLGLDEDLLGPGVAEG
EGAPTPN

Sequence length

487

Interactions

View interactions

	KEGG		Reactome
	Glycerophospholipid metabolism Metabolic pathways		Synthesis of PS

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (2)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Carcinoma Hepatocellular	Associate	38025761	★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosclerosis	Associate	37714410	★★★★★ ★☆☆☆☆ Found in Text Mining only

PTDSS2 (phosphatidylserine synthase 2)