Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
8110
Gene name Gene Name - the full gene name approved by the HGNC.
Double PHD fingers 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
DPF3
Synonyms (NCBI Gene) Gene synonyms aliases
BAF45C, CERD4, SMARCG3
Chromosome Chromosome number
14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
14q24.2
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the D4 protein family. The encoded protein is a transcription regulator that binds acetylated histones and is a component of the BAF chromatin remodeling complex. Alternate splicing results in multiple transcript variants enc
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT030041 hsa-miR-26b-5p Microarray 19088304
MIRT616346 hsa-miR-3613-3p HITS-CLIP 23824327
MIRT617327 hsa-miR-5088-3p HITS-CLIP 23824327
MIRT616345 hsa-miR-6814-3p HITS-CLIP 23824327
MIRT616344 hsa-miR-6872-5p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003712 Function Transcription coregulator activity IBA 21873635
GO:0005654 Component Nucleoplasm IDA
GO:0006325 Process Chromatin organization IEA
GO:0007399 Process Nervous system development IBA 21873635
GO:0008150 Process Biological_process ND
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
601672 17427 ENSG00000205683
Protein
UniProt ID Q92784
Protein name Zinc finger protein DPF3 (BRG1-associated factor 45C) (BAF45C) (Zinc finger protein cer-d4)
Protein function Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to
PDB 2KWJ , 2KWK , 2KWN , 2KWO , 5I3L , 5SZB , 5SZC
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF14051 Requiem_N 13 84 N-terminal domain of DPF2/REQ. Family
PF00628 PHD 261 319 PHD-finger Domain
PF00628 PHD 318 366 PHD-finger Domain
Sequence
MATVIHNPLKALGDQFYKEAIEHCRSYNSRLCAERSVRLPFLDSQTGVAQNNCYIWMEKR
HRGPGLAPGQLYTYPARCWRKKRR
LHPPEDPKLRLLEIKPEVELPLKKDGFTSESTTLEA
LLRGEGVEKKVDAREEESIQEIQRVLENDENVEEGNEEEDLEEDIPKRKNRTRGRARGSA
GGRRRHDAASQEDHDKPYVCDICGKRYKNRPGLSYHYAHTHLASEEGDEAQDQETRSPPN
HRNENHRPQKGPDGTVIPNNYCDFCLGGSNMNKKSGRPEELVSCADCGRSGHPTCLQFTL
NMTEAVKTYKWQCIECK
SCILCGTSENDDQLLFCDDCDRGYHMYCLNPPVAEPPEGSWSC
HLCWEL
LKEKASAFGCQA
Sequence length 378
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  ATP-dependent chromatin remodeling
Thermogenesis
Hepatocellular carcinoma
 
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Atrial fibrillation Atrial Fibrillation rs120074192, rs121908590, rs121908593, rs121434558, rs587776851, rs387906612, rs387906613, rs387906614, rs387906615, rs199472687, rs199472705, rs199473324, rs587777336, rs587777339, rs587777557
View all (6 more)
29892015, 30061737
Age-related macular degeneration Age related macular degeneration rs199474657, rs61750120, rs1800728, rs62654397, rs61749423, rs61751412, rs61749439, rs61751398, rs61752417, rs62645946, rs1801269, rs62646860, rs61750142, rs61750145, rs61750152
View all (20 more)
29346644
Renal carcinoma Renal Cell Carcinoma rs121913668, rs121913670, rs121913243, rs786202724 28598434, 31231134
Unknown
Disease term Disease name Evidence References Source
Paroxysmal atrial fibrillation Paroxysmal atrial fibrillation 29892015, 30061737 ClinVar
Atrial Fibrillation Atrial Fibrillation GWAS
Gout Gout GWAS
Renal Carcinoma Renal Carcinoma GWAS
Associations from Text Mining
Disease Name Relationship Type References
Alcoholism Associate 28981154
Antisocial Personality Disorder Associate 28981154
Asthenozoospermia Associate 27232852
Azoospermia Associate 28975488
Carcinoma Renal Cell Associate 34390653, 35148991, 35945219
Cleft Lip Associate 18978678
Congenital Abnormalities Associate 18978678
Enterocolitis Necrotizing Associate 28378556
Head and Neck Neoplasms Associate 24271036
Hypoxia Associate 35148991