EEPD1 (endonuclease/exonuclease/phosphatase family domain containing 1)

Gene

• Entrez ID: 80820
• Gene name: Endonuclease/exonuclease/phosphatase family domain containing 1
• Gene symbol: EEPD1
• Synonyms (NCBI Gene): HSPC107
• Chromosome: 7
• Chromosome location: 7p14.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT485633	hsa-miR-216b-3p	PAR-CLIP	23592263
MIRT485632	hsa-miR-939-3p	PAR-CLIP	23592263
MIRT485630	hsa-miR-6852-5p	PAR-CLIP	23592263
MIRT485631	hsa-miR-6742-3p	PAR-CLIP	23592263
MIRT485629	hsa-miR-8064	PAR-CLIP	23592263
MIRT485628	hsa-miR-4640-5p	PAR-CLIP	23592263
MIRT485627	hsa-miR-4726-5p	PAR-CLIP	23592263
MIRT485626	hsa-miR-6508-3p	PAR-CLIP	23592263
MIRT485625	hsa-miR-1343-3p	PAR-CLIP	23592263
MIRT485624	hsa-miR-6783-3p	PAR-CLIP	23592263
MIRT735153	hsa-miR-320b	Luciferase reporter assay, Western blotting, Microarray, Immunohistochemistry (IHC), qRT-PCR	33536383
MIRT485633	hsa-miR-216b-3p	PAR-CLIP	23592263
MIRT485632	hsa-miR-939-3p	PAR-CLIP	23592263
MIRT485630	hsa-miR-6852-5p	PAR-CLIP	23592263
MIRT485631	hsa-miR-6742-3p	PAR-CLIP	23592263
MIRT485629	hsa-miR-8064	PAR-CLIP	23592263
MIRT485628	hsa-miR-4640-5p	PAR-CLIP	23592263
MIRT485627	hsa-miR-4726-5p	PAR-CLIP	23592263
MIRT485626	hsa-miR-6508-3p	PAR-CLIP	23592263
MIRT485625	hsa-miR-1343-3p	PAR-CLIP	23592263
MIRT485624	hsa-miR-6783-3p	PAR-CLIP	23592263
MIRT735153	hsa-miR-320b	Luciferase reporter assay, Western blotting, Microarray, qRT-PCR	33536383
MIRT953410	hsa-miR-1279	CLIP-seq
MIRT953411	hsa-miR-1908	CLIP-seq
MIRT953412	hsa-miR-2355-5p	CLIP-seq
MIRT953413	hsa-miR-3065-5p	CLIP-seq
MIRT953414	hsa-miR-3151	CLIP-seq
MIRT953415	hsa-miR-3179	CLIP-seq
MIRT953416	hsa-miR-3180	CLIP-seq
MIRT953417	hsa-miR-3180-3p	CLIP-seq
MIRT953418	hsa-miR-3194-3p	CLIP-seq
MIRT953419	hsa-miR-3196	CLIP-seq
MIRT953420	hsa-miR-3199	CLIP-seq
MIRT953421	hsa-miR-3202	CLIP-seq
MIRT953422	hsa-miR-3652	CLIP-seq
MIRT953423	hsa-miR-3919	CLIP-seq
MIRT953424	hsa-miR-3921	CLIP-seq
MIRT953425	hsa-miR-3922-5p	CLIP-seq
MIRT953426	hsa-miR-3939	CLIP-seq
MIRT953427	hsa-miR-4251	CLIP-seq
MIRT953428	hsa-miR-4271	CLIP-seq
MIRT953429	hsa-miR-4329	CLIP-seq
MIRT953430	hsa-miR-4430	CLIP-seq
MIRT953431	hsa-miR-4446-3p	CLIP-seq
MIRT953432	hsa-miR-4488	CLIP-seq
MIRT953433	hsa-miR-4503	CLIP-seq
MIRT953434	hsa-miR-4505	CLIP-seq
MIRT953435	hsa-miR-4653-5p	CLIP-seq
MIRT953436	hsa-miR-4675	CLIP-seq
MIRT953437	hsa-miR-4697-5p	CLIP-seq
MIRT953438	hsa-miR-4708-3p	CLIP-seq
MIRT953439	hsa-miR-4721	CLIP-seq
MIRT953440	hsa-miR-4723-5p	CLIP-seq
MIRT953441	hsa-miR-4725-3p	CLIP-seq
MIRT953442	hsa-miR-4728-5p	CLIP-seq
MIRT953443	hsa-miR-4741	CLIP-seq
MIRT953444	hsa-miR-4747-5p	CLIP-seq
MIRT953445	hsa-miR-486-3p	CLIP-seq
MIRT953446	hsa-miR-512-5p	CLIP-seq
MIRT953447	hsa-miR-548c-3p	CLIP-seq
MIRT953448	hsa-miR-564	CLIP-seq
MIRT953449	hsa-miR-580	CLIP-seq
MIRT953450	hsa-miR-587	CLIP-seq
MIRT953451	hsa-miR-647	CLIP-seq
MIRT953452	hsa-miR-663	CLIP-seq
MIRT1548179	hsa-miR-1269	CLIP-seq
MIRT1548180	hsa-miR-1269b	CLIP-seq
MIRT1548181	hsa-miR-1287	CLIP-seq
MIRT1548182	hsa-miR-1288	CLIP-seq
MIRT1548183	hsa-miR-1538	CLIP-seq
MIRT1548184	hsa-miR-3135b	CLIP-seq
MIRT1548185	hsa-miR-378	CLIP-seq
MIRT1548186	hsa-miR-378b	CLIP-seq
MIRT1548187	hsa-miR-378c	CLIP-seq
MIRT1548188	hsa-miR-378d	CLIP-seq
MIRT1548189	hsa-miR-378e	CLIP-seq
MIRT1548190	hsa-miR-378f	CLIP-seq
MIRT1548191	hsa-miR-378h	CLIP-seq
MIRT1548192	hsa-miR-378i	CLIP-seq
MIRT1548193	hsa-miR-422a	CLIP-seq
MIRT1548194	hsa-miR-4318	CLIP-seq
MIRT1548195	hsa-miR-4515	CLIP-seq
MIRT1548196	hsa-miR-4740-5p	CLIP-seq
MIRT1548197	hsa-miR-4745-3p	CLIP-seq
MIRT1548198	hsa-miR-663b	CLIP-seq
MIRT1556256	hsa-miR-1275	CLIP-seq
MIRT953411	hsa-miR-1908	CLIP-seq
MIRT953415	hsa-miR-3179	CLIP-seq
MIRT953416	hsa-miR-3180	CLIP-seq
MIRT953417	hsa-miR-3180-3p	CLIP-seq
MIRT953419	hsa-miR-3196	CLIP-seq
MIRT953421	hsa-miR-3202	CLIP-seq
MIRT953428	hsa-miR-4271	CLIP-seq
MIRT953432	hsa-miR-4488	CLIP-seq
MIRT1556257	hsa-miR-4665-5p	CLIP-seq
MIRT953437	hsa-miR-4697-5p	CLIP-seq
MIRT953441	hsa-miR-4725-3p	CLIP-seq
MIRT953444	hsa-miR-4747-5p	CLIP-seq
MIRT1556258	hsa-miR-625	CLIP-seq
MIRT953452	hsa-miR-663	CLIP-seq
MIRT1982300	hsa-miR-1224-5p	CLIP-seq
MIRT1982301	hsa-miR-3150b-3p	CLIP-seq
MIRT1982302	hsa-miR-3915	CLIP-seq
MIRT1982303	hsa-miR-4689	CLIP-seq
MIRT1982304	hsa-miR-4784	CLIP-seq
MIRT2217097	hsa-miR-1246	CLIP-seq
MIRT2217098	hsa-miR-1290	CLIP-seq
MIRT2217099	hsa-miR-185	CLIP-seq
MIRT2217100	hsa-miR-3138	CLIP-seq
MIRT2217101	hsa-miR-3167	CLIP-seq
MIRT2217102	hsa-miR-3713	CLIP-seq
MIRT2217103	hsa-miR-3924	CLIP-seq
MIRT2217104	hsa-miR-4306	CLIP-seq
MIRT2217105	hsa-miR-4643	CLIP-seq
MIRT2217106	hsa-miR-4644	CLIP-seq
MIRT2217107	hsa-miR-4717-3p	CLIP-seq
MIRT2217108	hsa-miR-4802-3p	CLIP-seq
MIRT2217109	hsa-miR-490-5p	CLIP-seq
MIRT2217110	hsa-miR-548a-3p	CLIP-seq
MIRT2217111	hsa-miR-548e	CLIP-seq
MIRT2217112	hsa-miR-548f	CLIP-seq
MIRT2217113	hsa-miR-642b	CLIP-seq
MIRT2217114	hsa-miR-769-5p	CLIP-seq
MIRT2217115	hsa-miR-876-5p	CLIP-seq
MIRT2387221	hsa-miR-1200	CLIP-seq
MIRT2448681	hsa-miR-1248	CLIP-seq
MIRT1548183	hsa-miR-1538	CLIP-seq
MIRT2448682	hsa-miR-3127-3p	CLIP-seq
MIRT2448683	hsa-miR-3663-3p	CLIP-seq
MIRT2448684	hsa-miR-3714	CLIP-seq
MIRT953427	hsa-miR-4251	CLIP-seq
MIRT2448685	hsa-miR-4293	CLIP-seq
MIRT2448686	hsa-miR-4660	CLIP-seq
MIRT1548197	hsa-miR-4745-3p	CLIP-seq
MIRT2448687	hsa-miR-548an	CLIP-seq
MIRT953447	hsa-miR-548c-3p	CLIP-seq
MIRT953449	hsa-miR-580	CLIP-seq
MIRT1548179	hsa-miR-1269	CLIP-seq
MIRT1548180	hsa-miR-1269b	CLIP-seq
MIRT1548181	hsa-miR-1287	CLIP-seq
MIRT1548182	hsa-miR-1288	CLIP-seq
MIRT2521193	hsa-miR-1305	CLIP-seq
MIRT2521194	hsa-miR-1323	CLIP-seq
MIRT1548183	hsa-miR-1538	CLIP-seq
MIRT1548184	hsa-miR-3135b	CLIP-seq
MIRT2521195	hsa-miR-3140-5p	CLIP-seq
MIRT2521196	hsa-miR-3689d	CLIP-seq
MIRT1548185	hsa-miR-378	CLIP-seq
MIRT1548186	hsa-miR-378b	CLIP-seq
MIRT1548187	hsa-miR-378c	CLIP-seq
MIRT1548188	hsa-miR-378d	CLIP-seq
MIRT1548189	hsa-miR-378e	CLIP-seq
MIRT1548190	hsa-miR-378f	CLIP-seq
MIRT1548191	hsa-miR-378h	CLIP-seq
MIRT1548192	hsa-miR-378i	CLIP-seq
MIRT1548193	hsa-miR-422a	CLIP-seq
MIRT2521197	hsa-miR-4286	CLIP-seq
MIRT1548194	hsa-miR-4318	CLIP-seq
MIRT1548195	hsa-miR-4515	CLIP-seq
MIRT1548196	hsa-miR-4740-5p	CLIP-seq
MIRT1548197	hsa-miR-4745-3p	CLIP-seq
MIRT2521198	hsa-miR-4790-3p	CLIP-seq
MIRT953447	hsa-miR-548c-3p	CLIP-seq
MIRT2521199	hsa-miR-548o	CLIP-seq
MIRT953448	hsa-miR-564	CLIP-seq
MIRT2521200	hsa-miR-607	CLIP-seq
MIRT1548198	hsa-miR-663b	CLIP-seq
MIRT2448681	hsa-miR-1248	CLIP-seq
MIRT1548179	hsa-miR-1269	CLIP-seq
MIRT1548180	hsa-miR-1269b	CLIP-seq
MIRT1548181	hsa-miR-1287	CLIP-seq
MIRT1548182	hsa-miR-1288	CLIP-seq
MIRT2521193	hsa-miR-1305	CLIP-seq
MIRT2521194	hsa-miR-1323	CLIP-seq
MIRT1548183	hsa-miR-1538	CLIP-seq
MIRT2448682	hsa-miR-3127-3p	CLIP-seq
MIRT1548184	hsa-miR-3135b	CLIP-seq
MIRT2448683	hsa-miR-3663-3p	CLIP-seq
MIRT1548185	hsa-miR-378	CLIP-seq
MIRT1548186	hsa-miR-378b	CLIP-seq
MIRT1548187	hsa-miR-378c	CLIP-seq
MIRT1548188	hsa-miR-378d	CLIP-seq
MIRT1548189	hsa-miR-378e	CLIP-seq
MIRT1548190	hsa-miR-378f	CLIP-seq
MIRT1548191	hsa-miR-378h	CLIP-seq
MIRT1548192	hsa-miR-378i	CLIP-seq
MIRT1548193	hsa-miR-422a	CLIP-seq
MIRT2448685	hsa-miR-4293	CLIP-seq
MIRT1548194	hsa-miR-4318	CLIP-seq
MIRT1548195	hsa-miR-4515	CLIP-seq
MIRT1548196	hsa-miR-4740-5p	CLIP-seq
MIRT1548197	hsa-miR-4745-3p	CLIP-seq
MIRT953447	hsa-miR-548c-3p	CLIP-seq
MIRT2521199	hsa-miR-548o	CLIP-seq
MIRT2521200	hsa-miR-607	CLIP-seq
MIRT1548198	hsa-miR-663b	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0003824	Function	Catalytic activity	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IMP	28082258
GO:0005886	Component	Plasma membrane	TAS
GO:0006281	Process	DNA repair	IEA
GO:0010875	Process	Positive regulation of cholesterol efflux	IEA
GO:0010875	Process	Positive regulation of cholesterol efflux	IMP	28082258

Other IDs

• MIM: 617192
• HGNC: 22223
• e!Ensembl: ENSG00000122547

Protein

• UniProt ID: Q7L9B9
• Protein name: Endonuclease/exonuclease/phosphatase family domain-containing protein 1
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12836	HHH_3	35 → 99		Domain
  PF12836	HHH_3	134 → 196		Domain

• Sequence:

  MGSTLGCHRSIPRDPSDLSHSRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAV
  ARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICVSSKGSSAQHSPSSLRRDLLA
  EQQPHHLATAVPLTPRVNINTATPAQLMSVRGLSEKMALSIVDFRREHGPFRSVEDLVRM
  DGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQ
  IISTRPSVEAFGGTRDGRPVLRLATWNLQGCSVEKANNPGVREVVCMTLLENSIKLLAVQ
  ELLDREALEKFCTELNQPTLPNIRKWKGPRGCWKAVVAEKPSSQLQKGAGYAGFLWDAAA
  GMELRDAGSQESSPSNGHGKLAGPSPYLGRFKVGSHDLTLVNLHLAALTLLGSENPSKNH
  SDGHRLASFAQTLQETLKGEKDVIILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNIST
  KNPQGSKSLDNIWISKSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPVLAEFYT
  EKDWSKKDAPRNGSGVALERSEANIKHER

• Sequence length: 569

Pathways

Reactome:

NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux