Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	80820
Gene name Gene Name - the full gene name approved by the HGNC.	Endonuclease/exonuclease/phosphatase family domain containing 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	EEPD1
Synonyms (NCBI Gene) Gene synonyms aliases	HSPC107
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7p14.2

Show/Hide all(196)

miRTarBase ID	miRNA	Experiments	Reference
MIRT485633	hsa-miR-216b-3p	PAR-CLIP	23592263
MIRT485632	hsa-miR-939-3p	PAR-CLIP	23592263
MIRT485630	hsa-miR-6852-5p	PAR-CLIP	23592263
MIRT485631	hsa-miR-6742-3p	PAR-CLIP	23592263
MIRT485629	hsa-miR-8064	PAR-CLIP	23592263
MIRT485628	hsa-miR-4640-5p	PAR-CLIP	23592263
MIRT485627	hsa-miR-4726-5p	PAR-CLIP	23592263
MIRT485626	hsa-miR-6508-3p	PAR-CLIP	23592263
MIRT485625	hsa-miR-1343-3p	PAR-CLIP	23592263
MIRT485624	hsa-miR-6783-3p	PAR-CLIP	23592263
MIRT735153	hsa-miR-320b	Luciferase reporter assay, Western blotting, Microarray, Immunohistochemistry (IHC), qRT-PCR	33536383
MIRT485633	hsa-miR-216b-3p	PAR-CLIP	23592263
MIRT485632	hsa-miR-939-3p	PAR-CLIP	23592263
MIRT485630	hsa-miR-6852-5p	PAR-CLIP	23592263
MIRT485631	hsa-miR-6742-3p	PAR-CLIP	23592263
MIRT485629	hsa-miR-8064	PAR-CLIP	23592263
MIRT485628	hsa-miR-4640-5p	PAR-CLIP	23592263
MIRT485627	hsa-miR-4726-5p	PAR-CLIP	23592263
MIRT485626	hsa-miR-6508-3p	PAR-CLIP	23592263
MIRT485625	hsa-miR-1343-3p	PAR-CLIP	23592263
MIRT485624	hsa-miR-6783-3p	PAR-CLIP	23592263
MIRT735153	hsa-miR-320b	Luciferase reporter assay, Western blotting, Microarray, qRT-PCR	33536383
MIRT953410	hsa-miR-1279	CLIP-seq
MIRT953411	hsa-miR-1908	CLIP-seq
MIRT953412	hsa-miR-2355-5p	CLIP-seq
MIRT953413	hsa-miR-3065-5p	CLIP-seq
MIRT953414	hsa-miR-3151	CLIP-seq
MIRT953415	hsa-miR-3179	CLIP-seq
MIRT953416	hsa-miR-3180	CLIP-seq
MIRT953417	hsa-miR-3180-3p	CLIP-seq
MIRT953418	hsa-miR-3194-3p	CLIP-seq
MIRT953419	hsa-miR-3196	CLIP-seq
MIRT953420	hsa-miR-3199	CLIP-seq
MIRT953421	hsa-miR-3202	CLIP-seq
MIRT953422	hsa-miR-3652	CLIP-seq
MIRT953423	hsa-miR-3919	CLIP-seq
MIRT953424	hsa-miR-3921	CLIP-seq
MIRT953425	hsa-miR-3922-5p	CLIP-seq
MIRT953426	hsa-miR-3939	CLIP-seq
MIRT953427	hsa-miR-4251	CLIP-seq
MIRT953428	hsa-miR-4271	CLIP-seq
MIRT953429	hsa-miR-4329	CLIP-seq
MIRT953430	hsa-miR-4430	CLIP-seq
MIRT953431	hsa-miR-4446-3p	CLIP-seq
MIRT953432	hsa-miR-4488	CLIP-seq
MIRT953433	hsa-miR-4503	CLIP-seq
MIRT953434	hsa-miR-4505	CLIP-seq
MIRT953435	hsa-miR-4653-5p	CLIP-seq
MIRT953436	hsa-miR-4675	CLIP-seq
MIRT953437	hsa-miR-4697-5p	CLIP-seq
MIRT953438	hsa-miR-4708-3p	CLIP-seq
MIRT953439	hsa-miR-4721	CLIP-seq
MIRT953440	hsa-miR-4723-5p	CLIP-seq
MIRT953441	hsa-miR-4725-3p	CLIP-seq
MIRT953442	hsa-miR-4728-5p	CLIP-seq
MIRT953443	hsa-miR-4741	CLIP-seq
MIRT953444	hsa-miR-4747-5p	CLIP-seq
MIRT953445	hsa-miR-486-3p	CLIP-seq
MIRT953446	hsa-miR-512-5p	CLIP-seq
MIRT953447	hsa-miR-548c-3p	CLIP-seq
MIRT953448	hsa-miR-564	CLIP-seq
MIRT953449	hsa-miR-580	CLIP-seq
MIRT953450	hsa-miR-587	CLIP-seq
MIRT953451	hsa-miR-647	CLIP-seq
MIRT953452	hsa-miR-663	CLIP-seq
MIRT1548179	hsa-miR-1269	CLIP-seq
MIRT1548180	hsa-miR-1269b	CLIP-seq
MIRT1548181	hsa-miR-1287	CLIP-seq
MIRT1548182	hsa-miR-1288	CLIP-seq
MIRT1548183	hsa-miR-1538	CLIP-seq
MIRT1548184	hsa-miR-3135b	CLIP-seq
MIRT1548185	hsa-miR-378	CLIP-seq
MIRT1548186	hsa-miR-378b	CLIP-seq
MIRT1548187	hsa-miR-378c	CLIP-seq
MIRT1548188	hsa-miR-378d	CLIP-seq
MIRT1548189	hsa-miR-378e	CLIP-seq
MIRT1548190	hsa-miR-378f	CLIP-seq
MIRT1548191	hsa-miR-378h	CLIP-seq
MIRT1548192	hsa-miR-378i	CLIP-seq
MIRT1548193	hsa-miR-422a	CLIP-seq
MIRT1548194	hsa-miR-4318	CLIP-seq
MIRT1548195	hsa-miR-4515	CLIP-seq
MIRT1548196	hsa-miR-4740-5p	CLIP-seq
MIRT1548197	hsa-miR-4745-3p	CLIP-seq
MIRT1548198	hsa-miR-663b	CLIP-seq
MIRT1556256	hsa-miR-1275	CLIP-seq
MIRT953411	hsa-miR-1908	CLIP-seq
MIRT953415	hsa-miR-3179	CLIP-seq
MIRT953416	hsa-miR-3180	CLIP-seq
MIRT953417	hsa-miR-3180-3p	CLIP-seq
MIRT953419	hsa-miR-3196	CLIP-seq
MIRT953421	hsa-miR-3202	CLIP-seq
MIRT953428	hsa-miR-4271	CLIP-seq
MIRT953432	hsa-miR-4488	CLIP-seq
MIRT1556257	hsa-miR-4665-5p	CLIP-seq
MIRT953437	hsa-miR-4697-5p	CLIP-seq
MIRT953441	hsa-miR-4725-3p	CLIP-seq
MIRT953444	hsa-miR-4747-5p	CLIP-seq
MIRT1556258	hsa-miR-625	CLIP-seq
MIRT953452	hsa-miR-663	CLIP-seq
MIRT1982300	hsa-miR-1224-5p	CLIP-seq
MIRT1982301	hsa-miR-3150b-3p	CLIP-seq
MIRT1982302	hsa-miR-3915	CLIP-seq
MIRT1982303	hsa-miR-4689	CLIP-seq
MIRT1982304	hsa-miR-4784	CLIP-seq
MIRT2217097	hsa-miR-1246	CLIP-seq
MIRT2217098	hsa-miR-1290	CLIP-seq
MIRT2217099	hsa-miR-185	CLIP-seq
MIRT2217100	hsa-miR-3138	CLIP-seq
MIRT2217101	hsa-miR-3167	CLIP-seq
MIRT2217102	hsa-miR-3713	CLIP-seq
MIRT2217103	hsa-miR-3924	CLIP-seq
MIRT2217104	hsa-miR-4306	CLIP-seq
MIRT2217105	hsa-miR-4643	CLIP-seq
MIRT2217106	hsa-miR-4644	CLIP-seq
MIRT2217107	hsa-miR-4717-3p	CLIP-seq
MIRT2217108	hsa-miR-4802-3p	CLIP-seq
MIRT2217109	hsa-miR-490-5p	CLIP-seq
MIRT2217110	hsa-miR-548a-3p	CLIP-seq
MIRT2217111	hsa-miR-548e	CLIP-seq
MIRT2217112	hsa-miR-548f	CLIP-seq
MIRT2217113	hsa-miR-642b	CLIP-seq
MIRT2217114	hsa-miR-769-5p	CLIP-seq
MIRT2217115	hsa-miR-876-5p	CLIP-seq
MIRT2387221	hsa-miR-1200	CLIP-seq
MIRT2448681	hsa-miR-1248	CLIP-seq
MIRT1548183	hsa-miR-1538	CLIP-seq
MIRT2448682	hsa-miR-3127-3p	CLIP-seq
MIRT2448683	hsa-miR-3663-3p	CLIP-seq
MIRT2448684	hsa-miR-3714	CLIP-seq
MIRT953427	hsa-miR-4251	CLIP-seq
MIRT2448685	hsa-miR-4293	CLIP-seq
MIRT2448686	hsa-miR-4660	CLIP-seq
MIRT1548197	hsa-miR-4745-3p	CLIP-seq
MIRT2448687	hsa-miR-548an	CLIP-seq
MIRT953447	hsa-miR-548c-3p	CLIP-seq
MIRT953449	hsa-miR-580	CLIP-seq
MIRT1548179	hsa-miR-1269	CLIP-seq
MIRT1548180	hsa-miR-1269b	CLIP-seq
MIRT1548181	hsa-miR-1287	CLIP-seq
MIRT1548182	hsa-miR-1288	CLIP-seq
MIRT2521193	hsa-miR-1305	CLIP-seq
MIRT2521194	hsa-miR-1323	CLIP-seq
MIRT1548183	hsa-miR-1538	CLIP-seq
MIRT1548184	hsa-miR-3135b	CLIP-seq
MIRT2521195	hsa-miR-3140-5p	CLIP-seq
MIRT2521196	hsa-miR-3689d	CLIP-seq
MIRT1548185	hsa-miR-378	CLIP-seq
MIRT1548186	hsa-miR-378b	CLIP-seq
MIRT1548187	hsa-miR-378c	CLIP-seq
MIRT1548188	hsa-miR-378d	CLIP-seq
MIRT1548189	hsa-miR-378e	CLIP-seq
MIRT1548190	hsa-miR-378f	CLIP-seq
MIRT1548191	hsa-miR-378h	CLIP-seq
MIRT1548192	hsa-miR-378i	CLIP-seq
MIRT1548193	hsa-miR-422a	CLIP-seq
MIRT2521197	hsa-miR-4286	CLIP-seq
MIRT1548194	hsa-miR-4318	CLIP-seq
MIRT1548195	hsa-miR-4515	CLIP-seq
MIRT1548196	hsa-miR-4740-5p	CLIP-seq
MIRT1548197	hsa-miR-4745-3p	CLIP-seq
MIRT2521198	hsa-miR-4790-3p	CLIP-seq
MIRT953447	hsa-miR-548c-3p	CLIP-seq
MIRT2521199	hsa-miR-548o	CLIP-seq
MIRT953448	hsa-miR-564	CLIP-seq
MIRT2521200	hsa-miR-607	CLIP-seq
MIRT1548198	hsa-miR-663b	CLIP-seq
MIRT2448681	hsa-miR-1248	CLIP-seq
MIRT1548179	hsa-miR-1269	CLIP-seq
MIRT1548180	hsa-miR-1269b	CLIP-seq
MIRT1548181	hsa-miR-1287	CLIP-seq
MIRT1548182	hsa-miR-1288	CLIP-seq
MIRT2521193	hsa-miR-1305	CLIP-seq
MIRT2521194	hsa-miR-1323	CLIP-seq
MIRT1548183	hsa-miR-1538	CLIP-seq
MIRT2448682	hsa-miR-3127-3p	CLIP-seq
MIRT1548184	hsa-miR-3135b	CLIP-seq
MIRT2448683	hsa-miR-3663-3p	CLIP-seq
MIRT1548185	hsa-miR-378	CLIP-seq
MIRT1548186	hsa-miR-378b	CLIP-seq
MIRT1548187	hsa-miR-378c	CLIP-seq
MIRT1548188	hsa-miR-378d	CLIP-seq
MIRT1548189	hsa-miR-378e	CLIP-seq
MIRT1548190	hsa-miR-378f	CLIP-seq
MIRT1548191	hsa-miR-378h	CLIP-seq
MIRT1548192	hsa-miR-378i	CLIP-seq
MIRT1548193	hsa-miR-422a	CLIP-seq
MIRT2448685	hsa-miR-4293	CLIP-seq
MIRT1548194	hsa-miR-4318	CLIP-seq
MIRT1548195	hsa-miR-4515	CLIP-seq
MIRT1548196	hsa-miR-4740-5p	CLIP-seq
MIRT1548197	hsa-miR-4745-3p	CLIP-seq
MIRT953447	hsa-miR-548c-3p	CLIP-seq
MIRT2521199	hsa-miR-548o	CLIP-seq
MIRT2521200	hsa-miR-607	CLIP-seq
MIRT1548198	hsa-miR-663b	CLIP-seq

Show/Hide all(9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0003824	Function	Catalytic activity	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IMP	28082258
GO:0005886	Component	Plasma membrane	TAS
GO:0006281	Process	DNA repair	IEA
GO:0010875	Process	Positive regulation of cholesterol efflux	IEA
GO:0010875	Process	Positive regulation of cholesterol efflux	IMP	28082258

MIM	HGNC	e!Ensembl
617192	22223	ENSG00000122547

Protein

UniProt ID

Q7L9B9

Protein name

Endonuclease/exonuclease/phosphatase family domain-containing protein 1

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF12836	HHH_3	35 → 99		Domain
PF12836	HHH_3	134 → 196		Domain

Sequence

MGSTLGCHRSIPRDPSDLSHSRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAV
ARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICVSSKGSSAQHSPSSLRRDLLA
EQQPHHLATAVPLTPRVNINTATPAQLMSVRGLSEKMALSIVDFRREHGPFRSVEDLVRM
DGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQ
IISTRPSVEAFGGTRDGRPVLRLATWNLQGCSVEKANNPGVREVVCMTLLENSIKLLAVQ
ELLDREALEKFCTELNQPTLPNIRKWKGPRGCWKAVVAEKPSSQLQKGAGYAGFLWDAAA
GMELRDAGSQESSPSNGHGKLAGPSPYLGRFKVGSHDLTLVNLHLAALTLLGSENPSKNH
SDGHRLASFAQTLQETLKGEKDVIILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNIST
KNPQGSKSLDNIWISKSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPVLAEFYT
EKDWSKKDAPRNGSGVALERSEANIKHER

Sequence length

569

Interactions

View interactions

	Reactome
			NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Schizophrenia	Schizophrenia	N/A	N/A	GWAS

Show/Hide Text Mining Associations (5)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Breast Neoplasms	Associate	29145865
Colonic Neoplasms	Associate	38238555
Neoplasms	Associate	29145865, 38238555
Ovarian Neoplasms	Associate	34001952
Prostatic Neoplasms	Associate	34001952

EEPD1 (endonuclease/exonuclease/phosphatase family domain containing 1)