Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
80818
Gene name Gene Name - the full gene name approved by the HGNC.
Zinc finger protein 436
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ZNF436
Synonyms (NCBI Gene) Gene synonyms aliases
ZNF, Zfp46
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1p36.12
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT025873 hsa-miR-7-5p Sequencing 20371350
MIRT044808 hsa-miR-320a CLASH 23622248
MIRT039105 hsa-miR-769-3p CLASH 23622248
MIRT458975 hsa-miR-651-3p PAR-CLIP 23592263
MIRT458974 hsa-miR-4773 PAR-CLIP 23592263
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IBA 21873635
GO:0000977 Function RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA 21873635
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA 21873635
GO:0001227 Function DNA-binding transcription repressor activity, RNA polymerase II-specific IBA 21873635
GO:0005515 Function Protein binding IPI 23455924, 32296183, 32814053
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
611703 20814 ENSG00000125945
Protein
UniProt ID Q9C0F3
Protein name Zinc finger protein 436
Protein function May be a transcriptional repressor.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01352 KRAB 13 54 KRAB box Family
PF00096 zf-C2H2 138 160 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 166 188 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 194 216 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 222 244 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 250 272 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 278 300 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 306 328 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 334 356 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 362 384 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 390 412 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 418 440 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 446 468 Zinc finger, C2H2 type Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in fetal brain, heart, liver, spleen, bladder, lung, skin, skeletal muscle, stomach and pancreas. {ECO:0000269|PubMed:17089209}.
Sequence
Sequence length 470
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Generic Transcription Pathway
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Breast cancer Malignant neoplasm of breast rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158
View all (309 more)
Unknown
Disease term Disease name Evidence References Source
Kidney Disease Kidney Disease GWAS
Associations from Text Mining
Disease Name Relationship Type References
Breast Neoplasms Associate 33478201
Calcinosis Stimulate 35883646
Lymphatic Metastasis Associate 33478201
Neuroblastoma Inhibit 37904225