Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	8079
Gene name Gene Name - the full gene name approved by the HGNC.	Myeloid leukemia factor 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MLF2
Synonyms (NCBI Gene) Gene synonyms aliases	NTN4
Chromosome Chromosome number	12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	12p13.31

Show/Hide all(186)

miRTarBase ID	miRNA	Experiments	Reference
MIRT051088	hsa-miR-16-5p	CLASH	23622248
MIRT049518	hsa-miR-92a-3p	CLASH	23622248
MIRT038370	hsa-miR-296-3p	CLASH	23622248
MIRT037535	hsa-miR-744-5p	CLASH	23622248
MIRT655716	hsa-miR-4282	HITS-CLIP	23824327
MIRT655715	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT655714	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT655713	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT655712	hsa-miR-4662a-5p	HITS-CLIP	23824327
MIRT655711	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT655710	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT655716	hsa-miR-4282	HITS-CLIP	23824327
MIRT655715	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT655714	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT655713	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT655712	hsa-miR-4662a-5p	HITS-CLIP	23824327
MIRT655711	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT655710	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT1150968	hsa-miR-122	CLIP-seq
MIRT1150969	hsa-miR-1252	CLIP-seq
MIRT1150970	hsa-miR-147	CLIP-seq
MIRT1150971	hsa-miR-185	CLIP-seq
MIRT1150972	hsa-miR-186	CLIP-seq
MIRT1150973	hsa-miR-2110	CLIP-seq
MIRT1150974	hsa-miR-3125	CLIP-seq
MIRT1150975	hsa-miR-3126-5p	CLIP-seq
MIRT1150976	hsa-miR-3127-5p	CLIP-seq
MIRT1150977	hsa-miR-3148	CLIP-seq
MIRT1150978	hsa-miR-3150a-3p	CLIP-seq
MIRT1150979	hsa-miR-3154	CLIP-seq
MIRT1150980	hsa-miR-3184	CLIP-seq
MIRT1150981	hsa-miR-3613-3p	CLIP-seq
MIRT1150982	hsa-miR-3714	CLIP-seq
MIRT1150983	hsa-miR-3911	CLIP-seq
MIRT1150984	hsa-miR-3916	CLIP-seq
MIRT1150985	hsa-miR-3919	CLIP-seq
MIRT1150986	hsa-miR-4279	CLIP-seq
MIRT1150987	hsa-miR-4433	CLIP-seq
MIRT1150988	hsa-miR-4450	CLIP-seq
MIRT1150989	hsa-miR-4484	CLIP-seq
MIRT1150990	hsa-miR-4685-5p	CLIP-seq
MIRT1150991	hsa-miR-4719	CLIP-seq
MIRT1150992	hsa-miR-4802-5p	CLIP-seq
MIRT1150993	hsa-miR-486-5p	CLIP-seq
MIRT1150994	hsa-miR-541	CLIP-seq
MIRT1150995	hsa-miR-548an	CLIP-seq
MIRT1150996	hsa-miR-587	CLIP-seq
MIRT1150997	hsa-miR-644	CLIP-seq
MIRT1150998	hsa-miR-654-5p	CLIP-seq
MIRT1150973	hsa-miR-2110	CLIP-seq
MIRT1150974	hsa-miR-3125	CLIP-seq
MIRT1150975	hsa-miR-3126-5p	CLIP-seq
MIRT1150976	hsa-miR-3127-5p	CLIP-seq
MIRT1150977	hsa-miR-3148	CLIP-seq
MIRT1150978	hsa-miR-3150a-3p	CLIP-seq
MIRT2043062	hsa-miR-3915	CLIP-seq
MIRT1150984	hsa-miR-3916	CLIP-seq
MIRT2043063	hsa-miR-3921	CLIP-seq
MIRT2043064	hsa-miR-3928	CLIP-seq
MIRT1150986	hsa-miR-4279	CLIP-seq
MIRT2043065	hsa-miR-4283	CLIP-seq
MIRT2043066	hsa-miR-4447	CLIP-seq
MIRT1150988	hsa-miR-4450	CLIP-seq
MIRT2043067	hsa-miR-4472	CLIP-seq
MIRT2043068	hsa-miR-4488	CLIP-seq
MIRT2043069	hsa-miR-4649-3p	CLIP-seq
MIRT2043070	hsa-miR-4653-5p	CLIP-seq
MIRT1150990	hsa-miR-4685-5p	CLIP-seq
MIRT2043071	hsa-miR-4697-5p	CLIP-seq
MIRT2043072	hsa-miR-4749-3p	CLIP-seq
MIRT1150992	hsa-miR-4802-5p	CLIP-seq
MIRT1150994	hsa-miR-541	CLIP-seq
MIRT1150996	hsa-miR-587	CLIP-seq
MIRT1150998	hsa-miR-654-5p	CLIP-seq
MIRT2043073	hsa-miR-760	CLIP-seq
MIRT2043074	hsa-miR-889	CLIP-seq
MIRT1150969	hsa-miR-1252	CLIP-seq
MIRT1150970	hsa-miR-147	CLIP-seq
MIRT1150971	hsa-miR-185	CLIP-seq
MIRT1150972	hsa-miR-186	CLIP-seq
MIRT1150975	hsa-miR-3126-5p	CLIP-seq
MIRT1150979	hsa-miR-3154	CLIP-seq
MIRT2272555	hsa-miR-33a	CLIP-seq
MIRT2272556	hsa-miR-33b	CLIP-seq
MIRT1150981	hsa-miR-3613-3p	CLIP-seq
MIRT2272557	hsa-miR-3670	CLIP-seq
MIRT1150982	hsa-miR-3714	CLIP-seq
MIRT1150983	hsa-miR-3911	CLIP-seq
MIRT2043062	hsa-miR-3915	CLIP-seq
MIRT1150985	hsa-miR-3919	CLIP-seq
MIRT2043063	hsa-miR-3921	CLIP-seq
MIRT2043064	hsa-miR-3928	CLIP-seq
MIRT2043065	hsa-miR-4283	CLIP-seq
MIRT1150987	hsa-miR-4433	CLIP-seq
MIRT2043066	hsa-miR-4447	CLIP-seq
MIRT2043067	hsa-miR-4472	CLIP-seq
MIRT1150989	hsa-miR-4484	CLIP-seq
MIRT2043068	hsa-miR-4488	CLIP-seq
MIRT2043069	hsa-miR-4649-3p	CLIP-seq
MIRT2043070	hsa-miR-4653-5p	CLIP-seq
MIRT1150990	hsa-miR-4685-5p	CLIP-seq
MIRT2043071	hsa-miR-4697-5p	CLIP-seq
MIRT2272558	hsa-miR-4698	CLIP-seq
MIRT1150991	hsa-miR-4719	CLIP-seq
MIRT2272559	hsa-miR-4725-5p	CLIP-seq
MIRT1150992	hsa-miR-4802-5p	CLIP-seq
MIRT1150993	hsa-miR-486-5p	CLIP-seq
MIRT2272560	hsa-miR-488	CLIP-seq
MIRT2272561	hsa-miR-504	CLIP-seq
MIRT1150994	hsa-miR-541	CLIP-seq
MIRT1150995	hsa-miR-548an	CLIP-seq
MIRT2272562	hsa-miR-586	CLIP-seq
MIRT2272563	hsa-miR-622	CLIP-seq
MIRT1150997	hsa-miR-644	CLIP-seq
MIRT1150998	hsa-miR-654-5p	CLIP-seq
MIRT2043073	hsa-miR-760	CLIP-seq
MIRT1150979	hsa-miR-3154	CLIP-seq
MIRT1150981	hsa-miR-3613-3p	CLIP-seq
MIRT1150982	hsa-miR-3714	CLIP-seq
MIRT1150985	hsa-miR-3919	CLIP-seq
MIRT1150989	hsa-miR-4484	CLIP-seq
MIRT1150991	hsa-miR-4719	CLIP-seq
MIRT1150995	hsa-miR-548an	CLIP-seq
MIRT2454181	hsa-miR-1915	CLIP-seq
MIRT2454182	hsa-miR-361-3p	CLIP-seq
MIRT2454183	hsa-miR-4270	CLIP-seq
MIRT2454184	hsa-miR-4324	CLIP-seq
MIRT2454185	hsa-miR-4329	CLIP-seq
MIRT2454186	hsa-miR-4441	CLIP-seq
MIRT2043066	hsa-miR-4447	CLIP-seq
MIRT2043067	hsa-miR-4472	CLIP-seq
MIRT2454187	hsa-miR-4786-5p	CLIP-seq
MIRT2454188	hsa-miR-769-5p	CLIP-seq
MIRT1150968	hsa-miR-122	CLIP-seq
MIRT2454181	hsa-miR-1915	CLIP-seq
MIRT2571454	hsa-miR-2053	CLIP-seq
MIRT1150973	hsa-miR-2110	CLIP-seq
MIRT1150974	hsa-miR-3125	CLIP-seq
MIRT1150976	hsa-miR-3127-5p	CLIP-seq
MIRT1150977	hsa-miR-3148	CLIP-seq
MIRT1150978	hsa-miR-3150a-3p	CLIP-seq
MIRT1150980	hsa-miR-3184	CLIP-seq
MIRT2454182	hsa-miR-361-3p	CLIP-seq
MIRT1150984	hsa-miR-3916	CLIP-seq
MIRT2454183	hsa-miR-4270	CLIP-seq
MIRT1150987	hsa-miR-4433	CLIP-seq
MIRT2454186	hsa-miR-4441	CLIP-seq
MIRT2043066	hsa-miR-4447	CLIP-seq
MIRT1150988	hsa-miR-4450	CLIP-seq
MIRT2043067	hsa-miR-4472	CLIP-seq
MIRT2043068	hsa-miR-4488	CLIP-seq
MIRT2043071	hsa-miR-4697-5p	CLIP-seq
MIRT2272559	hsa-miR-4725-5p	CLIP-seq
MIRT2571455	hsa-miR-4775	CLIP-seq
MIRT2454187	hsa-miR-4786-5p	CLIP-seq
MIRT2272561	hsa-miR-504	CLIP-seq
MIRT2571456	hsa-miR-569	CLIP-seq
MIRT2454188	hsa-miR-769-5p	CLIP-seq
MIRT2043074	hsa-miR-889	CLIP-seq
MIRT1150968	hsa-miR-122	CLIP-seq
MIRT2454181	hsa-miR-1915	CLIP-seq
MIRT2571454	hsa-miR-2053	CLIP-seq
MIRT1150973	hsa-miR-2110	CLIP-seq
MIRT1150974	hsa-miR-3125	CLIP-seq
MIRT1150976	hsa-miR-3127-5p	CLIP-seq
MIRT1150977	hsa-miR-3148	CLIP-seq
MIRT1150978	hsa-miR-3150a-3p	CLIP-seq
MIRT1150980	hsa-miR-3184	CLIP-seq
MIRT2454182	hsa-miR-361-3p	CLIP-seq
MIRT1150984	hsa-miR-3916	CLIP-seq
MIRT2454183	hsa-miR-4270	CLIP-seq
MIRT1150987	hsa-miR-4433	CLIP-seq
MIRT2454186	hsa-miR-4441	CLIP-seq
MIRT2043066	hsa-miR-4447	CLIP-seq
MIRT1150988	hsa-miR-4450	CLIP-seq
MIRT2043067	hsa-miR-4472	CLIP-seq
MIRT2043068	hsa-miR-4488	CLIP-seq
MIRT1150990	hsa-miR-4685-5p	CLIP-seq
MIRT2043071	hsa-miR-4697-5p	CLIP-seq
MIRT2272559	hsa-miR-4725-5p	CLIP-seq
MIRT2571455	hsa-miR-4775	CLIP-seq
MIRT2454187	hsa-miR-4786-5p	CLIP-seq
MIRT2272561	hsa-miR-504	CLIP-seq
MIRT2571456	hsa-miR-569	CLIP-seq
MIRT2454188	hsa-miR-769-5p	CLIP-seq
MIRT2043074	hsa-miR-889	CLIP-seq

Show/Hide all(5)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	23414517, 25036637, 26496610
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0006355	Process	Regulation of transcription, DNA-templated	IBA	21873635
GO:0016020	Component	Membrane	HDA	19946888

MIM	HGNC	e!Ensembl
601401	7126	ENSG00000089693

Protein

UniProt ID

Q15773

Protein name

Myeloid leukemia factor 2 (Myelodysplasia-myeloid leukemia factor 2)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF10248	Mlf1IP	15 → 199	Myelodysplasia-myeloid leukemia factor 1-interacting protein	Family

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed.

Sequence

MFRFMRDVEPEDPMFLMDPFAIHRQHMSRMLSGGFGYSPFLSITDGNMPGTRPASRRMQQ
AGAVSPFGMLGMSGGFMDMFGMMNDMIGNMEHMTAGGNCQTFSSSTVISYSNTGDGAPKV
YQETSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHIRDRAHILQRSRNHRTGDQEERQD
YINLDESEAAAFDDEWRRETSRFRQQRPLEFRRLESSGAGGRRAEGPPRLAIQGPEDSPS
RQSRRYDW

Sequence length

248

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Colorectal cancer	Colorectal Carcinoma	rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800 View all (467 more)

Show/Hide Unknown Diseases (4)

Disease term	Disease name	Source
Unknown
Eczema	Eczema	GWAS
Insomnia	Insomnia	GWAS
Schizophrenia	Schizophrenia	GWAS
Restless Legs Syndrome	Restless Legs Syndrome	GWAS

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References
Associations from Text Mining
Blister	Associate	32342107
Breast Neoplasms	Associate	31388936
Cardiomyopathy Dilated	Associate	36042172
Leukemia	Associate	34557292

MLF2 (myeloid leukemia factor 2)