Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
80774
Gene name Gene Name - the full gene name approved by the HGNC.
LIM domain containing 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
LIMD2
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
17q23.3
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT020001 hsa-miR-375 Microarray 20215506
MIRT023120 hsa-miR-124-3p Microarray 18668037
MIRT493329 hsa-let-7a-5p PAR-CLIP 23592263
MIRT493328 hsa-miR-98-5p PAR-CLIP 23592263
MIRT493327 hsa-let-7g-5p PAR-CLIP 23592263
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956
GO:0005654 Component Nucleoplasm IDA
GO:0005829 Component Cytosol IDA
GO:0046872 Function Metal ion binding IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein
UniProt ID Q9BT23
Protein name LIM domain-containing protein 2
Protein function Acts as an activator of the protein-kinase ILK, thereby regulating cell motility (PubMed:24590809).
PDB 2LZU
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00412 LIM 40 96 LIM domain Domain
Sequence
MFQAAGAAQATPSHDAKGGGSSTVQRSKSFSLRAQVKETCAACQKTVYPMERLVADKLIF
HNSCFCCKHCHTKLSLGSYAALHGEFYCKPHFQQLF
KSKGNYDEGFGRKQHKELWAHKEV
DPGTKTA
Sequence length 127
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Breast cancer Malignant neoplasm of breast rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158
View all (309 more)
18925433
Breast carcinoma Breast Carcinoma rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451
View all (71 more)
18925433
Marfan syndrome Mammary Carcinoma, Human rs137854456, rs137854457, rs267606796, rs137854458, rs137854459, rs137854460, rs137854470, rs137854471, rs267606797, rs137854461, rs137854462, rs137854463, rs869025419, rs137854464, rs137854465
View all (942 more)
18925433
Associations from Text Mining
Disease Name Relationship Type References
Arthritis Rheumatoid Associate 34713769
Breast Neoplasms Associate 38116315
Inflammation Associate 34713769
Neoplasm Metastasis Associate 33238381
Neoplasms Associate 17699795, 33238381
Obesity Associate 27564309
Thyroid Cancer Papillary Associate 17699795, 33238381