Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	8038
Gene name Gene Name - the full gene name approved by the HGNC.	ADAM metallopeptidase domain 12
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ADAM12
Synonyms (NCBI Gene) Gene synonyms aliases	ADAM12-OT1, CAR10, MCMP, MCMPMltna, MLTN, MLTNA
Chromosome Chromosome number	10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	10q26.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle de

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miRTarBase ID	miRNA	Experiments	Reference
MIRT005667	hsa-miR-29b-3p	Luciferase reporter assay, Microarray, Northern blot, qRT-PCR	20971881
MIRT005667	hsa-miR-29b-3p	Luciferase reporter assay, Microarray, Northern blot, qRT-PCR	20971881
MIRT005667	hsa-miR-29b-3p	Luciferase reporter assay, Microarray, qRT-PCR	19956414
MIRT023733	hsa-miR-1-3p	Microarray	18668037
MIRT441266	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT441266	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT005667	hsa-miR-29b-3p	Luciferase reporter assay, qRT-PCR, Western blot	25886595
MIRT765913	hsa-miR-1266	CLIP-seq
MIRT765914	hsa-miR-188-3p	CLIP-seq
MIRT765915	hsa-miR-2964a-5p	CLIP-seq
MIRT765916	hsa-miR-3591-3p	CLIP-seq
MIRT765917	hsa-miR-4476	CLIP-seq
MIRT765918	hsa-miR-4518	CLIP-seq
MIRT765919	hsa-miR-4677-3p	CLIP-seq
MIRT765920	hsa-miR-4679	CLIP-seq
MIRT765921	hsa-miR-548n	CLIP-seq
MIRT765922	hsa-miR-562	CLIP-seq
MIRT765923	hsa-miR-600	CLIP-seq
MIRT765924	hsa-miR-103a	CLIP-seq
MIRT765925	hsa-miR-107	CLIP-seq
MIRT765926	hsa-miR-1184	CLIP-seq
MIRT765927	hsa-miR-1205	CLIP-seq
MIRT765928	hsa-miR-1208	CLIP-seq
MIRT765929	hsa-miR-15a	CLIP-seq
MIRT765930	hsa-miR-15b	CLIP-seq
MIRT765931	hsa-miR-16	CLIP-seq
MIRT765932	hsa-miR-195	CLIP-seq
MIRT765933	hsa-miR-3158-5p	CLIP-seq
MIRT765934	hsa-miR-3166	CLIP-seq
MIRT765935	hsa-miR-424	CLIP-seq
MIRT765936	hsa-miR-4325	CLIP-seq
MIRT765937	hsa-miR-452	CLIP-seq
MIRT765938	hsa-miR-4676-3p	CLIP-seq
MIRT765939	hsa-miR-4771	CLIP-seq
MIRT765940	hsa-miR-497	CLIP-seq
MIRT765941	hsa-miR-544	CLIP-seq
MIRT1545080	hsa-miR-1207-3p	CLIP-seq
MIRT1545081	hsa-miR-1275	CLIP-seq
MIRT1545082	hsa-miR-1288	CLIP-seq
MIRT1545083	hsa-miR-3120-5p	CLIP-seq
MIRT1545084	hsa-miR-3160-5p	CLIP-seq
MIRT1545085	hsa-miR-3199	CLIP-seq
MIRT1545086	hsa-miR-323b-3p	CLIP-seq
MIRT1545087	hsa-miR-374a	CLIP-seq
MIRT1545088	hsa-miR-374b	CLIP-seq
MIRT1545089	hsa-miR-4259	CLIP-seq
MIRT1545090	hsa-miR-4443	CLIP-seq
MIRT1545091	hsa-miR-4525	CLIP-seq
MIRT1545092	hsa-miR-4652-5p	CLIP-seq
MIRT1545093	hsa-miR-4665-5p	CLIP-seq
MIRT1545094	hsa-miR-4703-3p	CLIP-seq
MIRT1545095	hsa-miR-4715-5p	CLIP-seq
MIRT1545096	hsa-miR-4723-5p	CLIP-seq
MIRT1545097	hsa-miR-4731-5p	CLIP-seq
MIRT1545098	hsa-miR-4753-5p	CLIP-seq
MIRT1545099	hsa-miR-625	CLIP-seq
MIRT1545100	hsa-miR-637	CLIP-seq
MIRT1545101	hsa-miR-765	CLIP-seq
MIRT1925687	hsa-miR-125a-5p	CLIP-seq
MIRT1925688	hsa-miR-125b	CLIP-seq
MIRT1925689	hsa-miR-3918	CLIP-seq
MIRT1925690	hsa-miR-3924	CLIP-seq
MIRT1925691	hsa-miR-4319	CLIP-seq
MIRT1925692	hsa-miR-4512	CLIP-seq
MIRT1925693	hsa-miR-4652-3p	CLIP-seq
MIRT1925694	hsa-miR-4732-3p	CLIP-seq
MIRT1925695	hsa-miR-4766-5p	CLIP-seq
MIRT1925696	hsa-miR-670	CLIP-seq
MIRT2443123	hsa-miR-1200	CLIP-seq
MIRT2443124	hsa-miR-1225-3p	CLIP-seq
MIRT2443125	hsa-miR-1233	CLIP-seq
MIRT2443126	hsa-miR-378	CLIP-seq
MIRT2443127	hsa-miR-378b	CLIP-seq
MIRT2443128	hsa-miR-378c	CLIP-seq
MIRT2443129	hsa-miR-378d	CLIP-seq
MIRT2443130	hsa-miR-378e	CLIP-seq
MIRT2443131	hsa-miR-378f	CLIP-seq
MIRT2443132	hsa-miR-378h	CLIP-seq
MIRT2443133	hsa-miR-378i	CLIP-seq
MIRT2443134	hsa-miR-422a	CLIP-seq
MIRT2443135	hsa-miR-4324	CLIP-seq
MIRT2443136	hsa-miR-4667-3p	CLIP-seq
MIRT2443137	hsa-miR-4740-3p	CLIP-seq
MIRT2443138	hsa-miR-544b	CLIP-seq
MIRT2443139	hsa-miR-617	CLIP-seq
MIRT2469532	hsa-miR-1178	CLIP-seq
MIRT2469533	hsa-miR-1229	CLIP-seq
MIRT2469534	hsa-miR-1263	CLIP-seq
MIRT765913	hsa-miR-1266	CLIP-seq
MIRT2469535	hsa-miR-1273g	CLIP-seq
MIRT2469536	hsa-miR-1279	CLIP-seq
MIRT2469537	hsa-miR-128	CLIP-seq
MIRT2469538	hsa-miR-139-5p	CLIP-seq
MIRT2469539	hsa-miR-145	CLIP-seq
MIRT2469540	hsa-miR-149	CLIP-seq
MIRT765914	hsa-miR-188-3p	CLIP-seq
MIRT2469541	hsa-miR-200b	CLIP-seq
MIRT2469542	hsa-miR-200c	CLIP-seq
MIRT2469543	hsa-miR-2113	CLIP-seq
MIRT2469544	hsa-miR-2116	CLIP-seq
MIRT2469545	hsa-miR-2276	CLIP-seq
MIRT2469546	hsa-miR-27a	CLIP-seq
MIRT2469547	hsa-miR-27b	CLIP-seq
MIRT765915	hsa-miR-2964a-5p	CLIP-seq
MIRT2469548	hsa-miR-3064-5p	CLIP-seq
MIRT2469549	hsa-miR-3117-5p	CLIP-seq
MIRT1545083	hsa-miR-3120-5p	CLIP-seq
MIRT2469550	hsa-miR-3127-3p	CLIP-seq
MIRT2469551	hsa-miR-3140-3p	CLIP-seq
MIRT2469552	hsa-miR-3150a-5p	CLIP-seq
MIRT2469553	hsa-miR-3150b-5p	CLIP-seq
MIRT2469554	hsa-miR-3156-5p	CLIP-seq
MIRT2469555	hsa-miR-346	CLIP-seq
MIRT2469556	hsa-miR-3650	CLIP-seq
MIRT2469557	hsa-miR-3973	CLIP-seq
MIRT2469558	hsa-miR-4255	CLIP-seq
MIRT2469559	hsa-miR-4288	CLIP-seq
MIRT2469560	hsa-miR-429	CLIP-seq
MIRT2469561	hsa-miR-4307	CLIP-seq
MIRT2469562	hsa-miR-4328	CLIP-seq
MIRT2469563	hsa-miR-4421	CLIP-seq
MIRT2469564	hsa-miR-4474-3p	CLIP-seq
MIRT2469565	hsa-miR-4475	CLIP-seq
MIRT765918	hsa-miR-4518	CLIP-seq
MIRT2469566	hsa-miR-4522	CLIP-seq
MIRT1925693	hsa-miR-4652-3p	CLIP-seq
MIRT2469567	hsa-miR-4668-3p	CLIP-seq
MIRT765919	hsa-miR-4677-3p	CLIP-seq
MIRT2469568	hsa-miR-4677-5p	CLIP-seq
MIRT765920	hsa-miR-4679	CLIP-seq
MIRT2469569	hsa-miR-4726-3p	CLIP-seq
MIRT2469570	hsa-miR-4772-3p	CLIP-seq
MIRT2469571	hsa-miR-4775	CLIP-seq
MIRT2469572	hsa-miR-4794	CLIP-seq
MIRT2469573	hsa-miR-520g	CLIP-seq
MIRT2469574	hsa-miR-520h	CLIP-seq
MIRT2469575	hsa-miR-548c-3p	CLIP-seq
MIRT765921	hsa-miR-548n	CLIP-seq
MIRT2469576	hsa-miR-548t	CLIP-seq
MIRT2469577	hsa-miR-582-5p	CLIP-seq
MIRT2469578	hsa-miR-632	CLIP-seq
MIRT2469579	hsa-miR-644	CLIP-seq
MIRT2469580	hsa-miR-889	CLIP-seq
MIRT2469532	hsa-miR-1178	CLIP-seq
MIRT1545080	hsa-miR-1207-3p	CLIP-seq
MIRT2469534	hsa-miR-1263	CLIP-seq
MIRT765913	hsa-miR-1266	CLIP-seq
MIRT2469535	hsa-miR-1273g	CLIP-seq
MIRT1545081	hsa-miR-1275	CLIP-seq
MIRT2469536	hsa-miR-1279	CLIP-seq
MIRT2469537	hsa-miR-128	CLIP-seq
MIRT1545082	hsa-miR-1288	CLIP-seq
MIRT2469538	hsa-miR-139-5p	CLIP-seq
MIRT2469539	hsa-miR-145	CLIP-seq
MIRT2469540	hsa-miR-149	CLIP-seq
MIRT765914	hsa-miR-188-3p	CLIP-seq
MIRT2674374	hsa-miR-1976	CLIP-seq
MIRT2469541	hsa-miR-200b	CLIP-seq
MIRT2469542	hsa-miR-200c	CLIP-seq
MIRT2469543	hsa-miR-2113	CLIP-seq
MIRT2469544	hsa-miR-2116	CLIP-seq
MIRT2469545	hsa-miR-2276	CLIP-seq
MIRT2469546	hsa-miR-27a	CLIP-seq
MIRT2469547	hsa-miR-27b	CLIP-seq
MIRT765915	hsa-miR-2964a-5p	CLIP-seq
MIRT2469548	hsa-miR-3064-5p	CLIP-seq
MIRT2469549	hsa-miR-3117-5p	CLIP-seq
MIRT1545083	hsa-miR-3120-5p	CLIP-seq
MIRT2674375	hsa-miR-3121-3p	CLIP-seq
MIRT2469550	hsa-miR-3127-3p	CLIP-seq
MIRT2469551	hsa-miR-3140-3p	CLIP-seq
MIRT2469552	hsa-miR-3150a-5p	CLIP-seq
MIRT2469553	hsa-miR-3150b-5p	CLIP-seq
MIRT2469554	hsa-miR-3156-5p	CLIP-seq
MIRT2674376	hsa-miR-3160-3p	CLIP-seq
MIRT2674377	hsa-miR-3163	CLIP-seq
MIRT1545085	hsa-miR-3199	CLIP-seq
MIRT2674378	hsa-miR-320e	CLIP-seq
MIRT2469555	hsa-miR-346	CLIP-seq
MIRT2469556	hsa-miR-3650	CLIP-seq
MIRT2674379	hsa-miR-3662	CLIP-seq
MIRT2674380	hsa-miR-369-3p	CLIP-seq
MIRT1545087	hsa-miR-374a	CLIP-seq
MIRT1545088	hsa-miR-374b	CLIP-seq
MIRT2674381	hsa-miR-3921	CLIP-seq
MIRT2469557	hsa-miR-3973	CLIP-seq
MIRT2469558	hsa-miR-4255	CLIP-seq
MIRT1545089	hsa-miR-4259	CLIP-seq
MIRT2469559	hsa-miR-4288	CLIP-seq
MIRT2469560	hsa-miR-429	CLIP-seq
MIRT2469561	hsa-miR-4307	CLIP-seq
MIRT2469562	hsa-miR-4328	CLIP-seq
MIRT2469563	hsa-miR-4421	CLIP-seq
MIRT2469564	hsa-miR-4474-3p	CLIP-seq
MIRT2469565	hsa-miR-4475	CLIP-seq
MIRT2674382	hsa-miR-4487	CLIP-seq
MIRT2674383	hsa-miR-4490	CLIP-seq
MIRT2674384	hsa-miR-450b-3p	CLIP-seq
MIRT2674385	hsa-miR-4511	CLIP-seq
MIRT765918	hsa-miR-4518	CLIP-seq
MIRT2469566	hsa-miR-4522	CLIP-seq
MIRT1545091	hsa-miR-4525	CLIP-seq
MIRT1925693	hsa-miR-4652-3p	CLIP-seq
MIRT1545092	hsa-miR-4652-5p	CLIP-seq
MIRT2674386	hsa-miR-4653-5p	CLIP-seq
MIRT1545093	hsa-miR-4665-5p	CLIP-seq
MIRT2469567	hsa-miR-4668-3p	CLIP-seq
MIRT765919	hsa-miR-4677-3p	CLIP-seq
MIRT2469568	hsa-miR-4677-5p	CLIP-seq
MIRT765920	hsa-miR-4679	CLIP-seq
MIRT1545094	hsa-miR-4703-3p	CLIP-seq
MIRT2674387	hsa-miR-4713-3p	CLIP-seq
MIRT1545095	hsa-miR-4715-5p	CLIP-seq
MIRT1545096	hsa-miR-4723-5p	CLIP-seq
MIRT2469569	hsa-miR-4726-3p	CLIP-seq
MIRT1545097	hsa-miR-4731-5p	CLIP-seq
MIRT1925695	hsa-miR-4766-5p	CLIP-seq
MIRT2469570	hsa-miR-4772-3p	CLIP-seq
MIRT2674388	hsa-miR-4774-5p	CLIP-seq
MIRT2469571	hsa-miR-4775	CLIP-seq
MIRT2469572	hsa-miR-4794	CLIP-seq
MIRT2674389	hsa-miR-495	CLIP-seq
MIRT2469573	hsa-miR-520g	CLIP-seq
MIRT2469574	hsa-miR-520h	CLIP-seq
MIRT2674390	hsa-miR-526b	CLIP-seq
MIRT2674391	hsa-miR-548b-3p	CLIP-seq
MIRT2469575	hsa-miR-548c-3p	CLIP-seq
MIRT765921	hsa-miR-548n	CLIP-seq
MIRT2469576	hsa-miR-548t	CLIP-seq
MIRT2674392	hsa-miR-558	CLIP-seq
MIRT2469577	hsa-miR-582-5p	CLIP-seq
MIRT1545099	hsa-miR-625	CLIP-seq
MIRT2469578	hsa-miR-632	CLIP-seq
MIRT1545100	hsa-miR-637	CLIP-seq
MIRT2674393	hsa-miR-638	CLIP-seq
MIRT2469579	hsa-miR-644	CLIP-seq
MIRT2674394	hsa-miR-760	CLIP-seq
MIRT2674395	hsa-miR-769-3p	CLIP-seq
MIRT2469580	hsa-miR-889	CLIP-seq
MIRT2674396	hsa-miR-890	CLIP-seq

Transcription factors

Show/Hide all(1)

Transcription factor	Regulation	Reference
SKIL	Repression	20457602

Show/Hide all(21)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004222	Function	Metalloendopeptidase activity	IBA
GO:0004222	Function	Metalloendopeptidase activity	IEA
GO:0005515	Function	Protein binding	IPI	15574124, 25825872, 32296183
GO:0005576	Component	Extracellular region	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005886	Component	Plasma membrane	IDA	15280379
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0006508	Process	Proteolysis	IBA
GO:0006508	Process	Proteolysis	IEA
GO:0007155	Process	Cell adhesion	IEA
GO:0007520	Process	Myoblast fusion	TAS	7566181
GO:0008233	Function	Peptidase activity	IEA
GO:0008237	Function	Metallopeptidase activity	IEA
GO:0008237	Function	Metallopeptidase activity	TAS	9417060
GO:0016020	Component	Membrane	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0017124	Function	SH3 domain binding	IEA
GO:0017124	Function	SH3 domain binding	IPI	15280379
GO:0045766	Process	Positive regulation of angiogenesis	IMP	28637396
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
602714	190	ENSG00000148848

Protein

UniProt ID

O43184

Protein name

Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha)

Protein function

Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors (By similarity).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01562	Pep_M12B_propep	42 → 167	Reprolysin family propeptide	Family
PF01421	Reprolysin	214 → 416	Reprolysin (M12B) family zinc metalloprotease	Domain
PF00200	Disintegrin	433 → 505	Disintegrin	Domain
PF08516	ADAM_CR	510 → 630	ADAM cysteine-rich	Family

Tissue specificity

TISSUE SPECIFICITY: Isoform 1 is expressed in placenta and skeletal, cardiac, and smooth muscle. Isoform 2 seems to be expressed only in placenta or in embryo and fetus. Both forms were expressed in some tumor cells lines. Not detected in brain, lung, liv

Sequence

MAARPLPVSPARALLLALAGALLAPCEARGVSLWNQGRADEVVSASVGSGDLWIPVKSFD
SKNHPEVLNIRLQRESKELIINLERNEGLIASSFTETHYLQDGTDVSLARNYTVILGHCY
YHGHVRGYSDSAVSLSTCSGLRGLIVFENESYVLEPMKSATNRYKLFPAKKLKSVRGSCG
SHHNTPNLAAKNVFPPPSQTWARRHKRETLKATKYVELVIVADNREFQRQGKDLEKVKQR
LIEIANHVDKFYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKSH
DNAQLVSGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNH
DTLDRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRE
SFGGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAGT
ACRDSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLWGPG
AKPAPGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAVS
IETNIPLQQGGRILCRGTHVYLGDDMPDPGLVLAGTKCADGKICLNRQCQNISVFGVHEC
AMQCHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTIGILVTILCL
LAAGFVVYLKRKTLIRLLFTNKKTTIEKLRCVRPSRPPRGFQPCQAHLGHLGKGLMRKPP
DSYPPKDNPRRLLQCQNVDISRPLNGLNVPQPQSTQRVLPPLHRAPRAPSVPARPLPAKP
ALRQAQGTCKPNPPQKPLPADPLARTTRLTHALARTPGQWETGLRLAPLRPAPQYPHQVP
RSTHTAYIK

Sequence length

909

Interactions

View interactions

	Reactome
			Invadopodia formation

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Hypogonadism	Hypogonadism	N/A	N/A	GWAS

Show/Hide Text Mining Associations (70)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Arthritis	Associate	21173277
Asthma	Stimulate	17088949
Astrocytoma	Associate	23324579
Breast Diseases	Stimulate	21240579
Breast Neoplasms	Associate	10329602, 16213489, 20688878, 21103624, 21240579, 21387162, 21493715, 22302350, 22662180, 23771733, 24651654, 26407179, 26722530, 35459884
Breast Neoplasms	Stimulate	15565459
Carcinoma Adenoid Cystic	Associate	24499112, 32386517
Carcinoma Hepatocellular	Associate	35459884
Carcinoma Non Small Cell Lung	Associate	16495931, 27557513
Carcinoma Ovarian Epithelial	Associate	21617380
Carcinoma Renal Cell	Associate	35094638, 36717944
Carcinoma Squamous Cell	Associate	21986939
Cardiomegaly	Associate	21173277
Cartilage Diseases	Associate	18311789, 30033738
Chemical and Drug Induced Liver Injury	Associate	18621736
Choriocarcinoma	Associate	32319603
Colorectal Neoplasms	Associate	30746900, 35413826
Conjunctival Diseases	Associate	36398070
Depressive Disorder Major	Associate	39501335
Drug Hypersensitivity	Associate	19213876
Fetal Growth Retardation	Inhibit	23583218
Fibromatosis Aggressive	Associate	24402778
Giant Cell Tumor of Bone	Associate	12456779
Glioblastoma	Associate	15509542, 29267965
Glioma	Associate	15509542
Growth Disorders	Associate	27545300
Head and Neck Neoplasms	Associate	21986939
Hereditary Breast and Ovarian Cancer Syndrome	Associate	21240579
Hereditary pancreatitis	Stimulate	23324579
Hypoxia	Stimulate	23589494
Hypoxia Brain	Associate	32386517
IgA Vasculitis	Associate	39235446
Inflammation	Associate	32319603
Inflammatory Bowel Diseases	Associate	39501335
Kashin Beck Disease	Associate	27545300, 29514696
Leiomyoma	Associate	25268745
Leukemia Lymphocytic Chronic B Cell	Associate	20495622, 33507683
Liver Cirrhosis Biliary	Associate	27545300
Liver Failure	Associate	18621736
Lymphatic Metastasis	Associate	36099146
Melanoma	Associate	23645517
Neoplasm Metastasis	Associate	20688878, 21493715, 32386517, 35094638, 35315496, 36717944, 37847945
Neoplasms	Associate	10329602, 12456779, 21103624, 21173277, 21240579, 21387162, 21493715, 21617380, 22662180, 22677901, 23324579, 23589494, 24402778, 25926422, 26407179 View all (13 more)
Neoplasms	Stimulate	16213489, 16495931, 20688878, 26722530
Neoplasms	Inhibit	33507683
Odontogenic Cysts	Associate	31319505
Oligodendroglioma	Associate	23324579
Osteoarthritis	Associate	15334463, 19268722, 25197389, 25667922, 29514696
Osteoarthritis Knee	Associate	16453284, 19268722, 25197389, 25667922
Osteophyte	Associate	19268722
Otitis Media	Associate	24499112
Ovarian Neoplasms	Associate	25926422, 27685922
Pancreatic Neoplasms	Associate	22984426
Patellofemoral Pain Syndrome	Associate	19268722
Pre Eclampsia	Associate	23770704
Pregnancy in Diabetics	Associate	35588731
Prostatic Neoplasms	Associate	31013576
Prostatitis	Associate	20688878
Pterygium	Associate	36398070
Rectal Neoplasms	Associate	35413826
Rhabdomyosarcoma	Associate	15574885
Rhinitis Allergic	Associate	19213876
Scleroderma Diffuse	Associate	24812288
Scleroderma Systemic	Associate	28861129
Small Cell Lung Carcinoma	Associate	33761685
Squamous Cell Carcinoma of Head and Neck	Associate	21986939, 34587717
Stomach Neoplasms	Associate	22677901, 34663825, 34686626, 35315496, 36099146, 37847945
Triple Negative Breast Neoplasms	Associate	24651654, 32019179, 39742357
Urinary Bladder Neoplasms	Associate	31013576
Uveal melanoma	Associate	33387485

ADAM12 (ADAM metallopeptidase domain 12)