Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	80345
Gene name Gene Name - the full gene name approved by the HGNC.	Zinc finger and SCAN domain containing 16
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ZSCAN16
Synonyms (NCBI Gene) Gene synonyms aliases	ZNF392, ZNF435, dJ265C24.3
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6p22.1

Show/Hide all(126)

miRTarBase ID	miRNA	Experiments	Reference
MIRT028787	hsa-miR-26b-5p	Microarray	19088304
MIRT723121	hsa-miR-580-5p	HITS-CLIP	19536157
MIRT723120	hsa-miR-646	HITS-CLIP	19536157
MIRT723119	hsa-miR-6736-3p	HITS-CLIP	19536157
MIRT723118	hsa-miR-4530	HITS-CLIP	19536157
MIRT723117	hsa-miR-3183	HITS-CLIP	19536157
MIRT723116	hsa-miR-4723-3p	HITS-CLIP	19536157
MIRT723115	hsa-miR-6769b-3p	HITS-CLIP	19536157
MIRT723114	hsa-miR-4660	HITS-CLIP	19536157
MIRT723113	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT723112	hsa-miR-7111-3p	HITS-CLIP	19536157
MIRT663576	hsa-miR-4494	HITS-CLIP	23824327
MIRT663575	hsa-miR-5193	HITS-CLIP	23824327
MIRT663574	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT663573	hsa-miR-5002-3p	HITS-CLIP	23824327
MIRT663572	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT663571	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT663570	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT663569	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT663568	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT663567	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT663566	hsa-miR-670-3p	HITS-CLIP	23824327
MIRT663565	hsa-miR-1238-3p	HITS-CLIP	23824327
MIRT529622	hsa-miR-3646	PAR-CLIP	22012620
MIRT529623	hsa-miR-4640-3p	PAR-CLIP	22012620
MIRT529621	hsa-miR-3127-3p	PAR-CLIP	22012620
MIRT529620	hsa-miR-6756-3p	PAR-CLIP	22012620
MIRT529619	hsa-miR-454-5p	PAR-CLIP	22012620
MIRT529618	hsa-miR-6734-3p	PAR-CLIP	22012620
MIRT529617	hsa-miR-494-3p	PAR-CLIP	22012620
MIRT529616	hsa-miR-6798-3p	PAR-CLIP	22012620
MIRT529615	hsa-miR-6883-3p	PAR-CLIP	22012620
MIRT496403	hsa-miR-499a-3p	PAR-CLIP	22291592
MIRT496402	hsa-miR-499b-3p	PAR-CLIP	22291592
MIRT496401	hsa-miR-3929	PAR-CLIP	22291592
MIRT496400	hsa-miR-4419b	PAR-CLIP	22291592
MIRT496399	hsa-miR-4478	PAR-CLIP	22291592
MIRT496398	hsa-miR-382-3p	PAR-CLIP	22291592
MIRT496397	hsa-miR-645	PAR-CLIP	22291592
MIRT496396	hsa-miR-626	PAR-CLIP	22291592
MIRT496395	hsa-miR-6876-3p	PAR-CLIP	22291592
MIRT446573	hsa-miR-186-5p	PAR-CLIP	22100165
MIRT446572	hsa-miR-4766-5p	PAR-CLIP	22100165
MIRT446571	hsa-miR-145-3p	PAR-CLIP	22100165
MIRT446570	hsa-miR-3160-5p	PAR-CLIP	22100165
MIRT446569	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT446568	hsa-miR-4762-3p	PAR-CLIP	22100165
MIRT446573	hsa-miR-186-5p	PAR-CLIP	22100165
MIRT446572	hsa-miR-4766-5p	PAR-CLIP	22100165
MIRT446571	hsa-miR-145-3p	PAR-CLIP	22100165
MIRT446570	hsa-miR-3160-5p	PAR-CLIP	22100165
MIRT446569	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT446568	hsa-miR-4762-3p	PAR-CLIP	22100165
MIRT723121	hsa-miR-580-5p	HITS-CLIP	19536157
MIRT723120	hsa-miR-646	HITS-CLIP	19536157
MIRT723119	hsa-miR-6736-3p	HITS-CLIP	19536157
MIRT723118	hsa-miR-4530	HITS-CLIP	19536157
MIRT723117	hsa-miR-3183	HITS-CLIP	19536157
MIRT723116	hsa-miR-4723-3p	HITS-CLIP	19536157
MIRT723115	hsa-miR-6769b-3p	HITS-CLIP	19536157
MIRT723114	hsa-miR-4660	HITS-CLIP	19536157
MIRT723113	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT723112	hsa-miR-7111-3p	HITS-CLIP	19536157
MIRT663576	hsa-miR-4494	HITS-CLIP	23824327
MIRT663575	hsa-miR-5193	HITS-CLIP	23824327
MIRT663574	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT663573	hsa-miR-5002-3p	HITS-CLIP	23824327
MIRT663572	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT663571	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT663570	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT663569	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT663568	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT663567	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT663566	hsa-miR-670-3p	HITS-CLIP	23824327
MIRT663565	hsa-miR-1238-3p	HITS-CLIP	23824327
MIRT529622	hsa-miR-3646	PAR-CLIP	22012620
MIRT529623	hsa-miR-4640-3p	PAR-CLIP	22012620
MIRT529621	hsa-miR-3127-3p	PAR-CLIP	22012620
MIRT529620	hsa-miR-6756-3p	PAR-CLIP	22012620
MIRT529619	hsa-miR-454-5p	PAR-CLIP	22012620
MIRT529618	hsa-miR-6734-3p	PAR-CLIP	22012620
MIRT529617	hsa-miR-494-3p	PAR-CLIP	22012620
MIRT529616	hsa-miR-6798-3p	PAR-CLIP	22012620
MIRT529615	hsa-miR-6883-3p	PAR-CLIP	22012620
MIRT496403	hsa-miR-499a-3p	PAR-CLIP	22291592
MIRT496402	hsa-miR-499b-3p	PAR-CLIP	22291592
MIRT496401	hsa-miR-3929	PAR-CLIP	22291592
MIRT496400	hsa-miR-4419b	PAR-CLIP	22291592
MIRT496399	hsa-miR-4478	PAR-CLIP	22291592
MIRT496398	hsa-miR-382-3p	PAR-CLIP	22291592
MIRT496397	hsa-miR-645	PAR-CLIP	22291592
MIRT496396	hsa-miR-626	PAR-CLIP	22291592
MIRT496395	hsa-miR-6876-3p	PAR-CLIP	22291592
MIRT446573	hsa-miR-186-5p	PAR-CLIP	22100165
MIRT446572	hsa-miR-4766-5p	PAR-CLIP	22100165
MIRT446571	hsa-miR-145-3p	PAR-CLIP	22100165
MIRT446570	hsa-miR-3160-5p	PAR-CLIP	22100165
MIRT446569	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT446568	hsa-miR-4762-3p	PAR-CLIP	22100165
MIRT446573	hsa-miR-186-5p	PAR-CLIP	22100165
MIRT446572	hsa-miR-4766-5p	PAR-CLIP	22100165
MIRT446571	hsa-miR-145-3p	PAR-CLIP	22100165
MIRT446570	hsa-miR-3160-5p	PAR-CLIP	22100165
MIRT446569	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT446568	hsa-miR-4762-3p	PAR-CLIP	22100165
MIRT2164006	hsa-miR-1272	CLIP-seq
MIRT2164007	hsa-miR-127-5p	CLIP-seq
MIRT2164008	hsa-miR-3136-5p	CLIP-seq
MIRT2164009	hsa-miR-4439	CLIP-seq
MIRT2164010	hsa-miR-4513	CLIP-seq
MIRT2164006	hsa-miR-1272	CLIP-seq
MIRT2164007	hsa-miR-127-5p	CLIP-seq
MIRT2383174	hsa-miR-133a	CLIP-seq
MIRT2383175	hsa-miR-133b	CLIP-seq
MIRT2383176	hsa-miR-198	CLIP-seq
MIRT2164008	hsa-miR-3136-5p	CLIP-seq
MIRT2383177	hsa-miR-3919	CLIP-seq
MIRT2164009	hsa-miR-4439	CLIP-seq
MIRT2164010	hsa-miR-4513	CLIP-seq
MIRT2383178	hsa-miR-520a-5p	CLIP-seq
MIRT2383179	hsa-miR-525-5p	CLIP-seq
MIRT2164006	hsa-miR-1272	CLIP-seq
MIRT2164007	hsa-miR-127-5p	CLIP-seq
MIRT2164008	hsa-miR-3136-5p	CLIP-seq
MIRT2164009	hsa-miR-4439	CLIP-seq
MIRT2164010	hsa-miR-4513	CLIP-seq

Show/Hide all(7)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	21873635
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	21873635
GO:0005515	Function	Protein binding	IPI	16189514, 25416956, 32296183, 32814053
GO:0005634	Component	Nucleus	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA	21873635
GO:0046872	Function	Metal ion binding	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
618544	20813	ENSG00000196812

Protein

UniProt ID

Q9H4T2

Protein name

Zinc finger and SCAN domain-containing protein 16 (Zinc finger protein 392) (Zinc finger protein 435)

Protein function

May be involved in transcriptional regulation.

PDB

2COT

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02023	SCAN	37 → 126	SCAN domain	Domain
PF00096	zf-C2H2	236 → 258	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	264 → 286	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	292 → 314	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	320 → 342	Zinc finger, C2H2 type	Domain

Sequence

MTTALEPEDQKGLLIIKAEDHYWGQDSSSQKCSPHRRELYRQHFRKLCYQDAPGPREALT
QLWELCRQWLRPECHTKEQILDLLVLEQFLSILPKDLQAWVRAHHPETGEEAVTVLEDLE
RELDEPGKQVPGNSERRDILMDKLAPLGRPYESLTVQLHPKKTQLEQEAGKPQRNGDKTR
TKNEELFQKEDMPKDKEFLGEINDRLNKDTPQHPKSKDIIENEGRSEWQQRERRRYKCDE
CGKSFSHSSDLSKHRRTHTGEKPYKCDECGKAFIQRSHLIGHHRVHTGVKPYKCKECGKD
FSGRTGLIQHQRIHTGEKPYECDECGRPFRVSSALIRHQRIHTANKLY

Sequence length

348

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Colorectal cancer	Colorectal Carcinoma	rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800 View all (467 more)

Show/Hide Unknown Diseases (9)

Disease term	Disease name	Evidence	Source
Unknown
Parkinson Disease	Parkinson Disease		GWAS
Cervical Cancer	Cervical Cancer	Our screens identified 10 miRNAs that enhance fitness of HeLa cells and have been reported to be up-regulated in cervical cancer (Table2).	GWAS, CBGDA
Mental Depression	Mental Depression		GWAS
Neuroticism	Neuroticism		GWAS
Schizophrenia	Schizophrenia		GWAS
Breast Cancer	Breast Cancer	Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients	GWAS, CBGDA
Psoriasis	Psoriasis		GWAS
Dental caries	Dental caries		GWAS
Colorectal Cancer	Colorectal Cancer	In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1.	GWAS, CBGDA

Show/Hide Text Mining Associations (1)

Disease Name	Relationship Type	References
Associations from Text Mining
Ovarian Neoplasms	Associate	32332753

ZSCAN16 (zinc finger and SCAN domain containing 16)