WDR82 (WD repeat domain 82)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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80335 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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WD repeat domain 82 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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WDR82 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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MST107, MSTP107, PRO2730, PRO34047, SWD2, TMEM113, WDR82A |
Chromosome
Chromosome number
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3 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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3p21.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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TMEM113 (WDR82) is a component of the mammalian SET1A (MIM 611052)/SET1B (MIM 611055) histone H3-Lys4 methyltransferase complexes (Lee and Skalnik, 2005 [PubMed 16253997]; Lee et al., 2007 [PubMed 17355966]).[supplied by OMIM, Jul 2010] |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||||||||||||
UniProt ID | Q6UXN9 | ||||||||||||||||||||
Protein name | WD repeat-containing protein 82 | ||||||||||||||||||||
Protein function | Regulatory component of the SET1/COMPASS complex implicated in the tethering of this complex to transcriptional start sites of active genes (PubMed:17998332, PubMed:18838538, PubMed:20516061). Facilitates histone H3 'Lys-4' methylation (H3K4me) | ||||||||||||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 313 | ||||||||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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