Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
80335
Gene name Gene Name - the full gene name approved by the HGNC.
WD repeat domain 82
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
WDR82
Synonyms (NCBI Gene) Gene synonyms aliases
MST107, MSTP107, PRO2730, PRO34047, SWD2, TMEM113, WDR82A
Chromosome Chromosome number
3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3p21.2
Summary Summary of gene provided in NCBI Entrez Gene.
TMEM113 (WDR82) is a component of the mammalian SET1A (MIM 611052)/SET1B (MIM 611055) histone H3-Lys4 methyltransferase complexes (Lee and Skalnik, 2005 [PubMed 16253997]; Lee et al., 2007 [PubMed 17355966]).[supplied by OMIM, Jul 2010]
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT005216 hsa-miR-30a-5p pSILAC 18668040
MIRT028388 hsa-miR-30a-3p qRT-PCR 16239240
MIRT005216 hsa-miR-30a-5p Proteomics;Other 18668040
MIRT050892 hsa-miR-17-5p CLASH 23622248
MIRT040688 hsa-miR-92b-3p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000781 Component Chromosome, telomeric region IDA 24270157
GO:0000785 Component Chromatin IDA 20516061
GO:0003682 Function Chromatin binding IBA 21873635
GO:0005515 Function Protein binding IPI 17998332, 18838538, 20516061
GO:0005730 Component Nucleolus IDA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
611059 28826 ENSG00000164091
Protein
UniProt ID Q6UXN9
Protein name WD repeat-containing protein 82
Protein function Regulatory component of the SET1/COMPASS complex implicated in the tethering of this complex to transcriptional start sites of active genes (PubMed:17998332, PubMed:18838538, PubMed:20516061). Facilitates histone H3 'Lys-4' methylation (H3K4me)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00400 WD40 9 49 WD domain, G-beta repeat Repeat
PF00400 WD40 97 135 WD domain, G-beta repeat Repeat
PF00400 WD40 226 267 WD domain, G-beta repeat Repeat
Sequence
MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLY
SKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDD
TFISGSLDKTIRLWD
LRSPNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFD
KGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKA
VTLEASFTPDSQFIMIGSEDGKIHVWN
GESGIKVAVLDGKHTGPITCLQFNPKFMTFASA
CSNMAFWLPTIDD
Sequence length 313
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  mRNA surveillance pathway  
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Schizophrenia Schizophrenia GWAS
Associations from Text Mining
Disease Name Relationship Type References
Glomerulonephritis IGA Associate 33319642