Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	80323
Gene name Gene Name - the full gene name approved by the HGNC.	Coiled-coil domain containing 68
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CCDC68
Synonyms (NCBI Gene) Gene synonyms aliases	SE57-1
Chromosome Chromosome number	18
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	18q21.2

Show/Hide all(62)

miRTarBase ID	miRNA	Experiments	Reference
MIRT022785	hsa-miR-124-3p	Microarray	18668037
MIRT628349	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT628348	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT628347	hsa-miR-940	HITS-CLIP	23824327
MIRT628346	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT628345	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT628344	hsa-miR-1827	HITS-CLIP	23824327
MIRT628343	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT628342	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT628341	hsa-miR-665	HITS-CLIP	23824327
MIRT628349	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT628348	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT628347	hsa-miR-940	HITS-CLIP	23824327
MIRT628346	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT628345	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT628344	hsa-miR-1827	HITS-CLIP	23824327
MIRT628343	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT628342	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT628341	hsa-miR-665	HITS-CLIP	23824327
MIRT869641	hsa-miR-106a	CLIP-seq
MIRT869642	hsa-miR-106b	CLIP-seq
MIRT869643	hsa-miR-147	CLIP-seq
MIRT869644	hsa-miR-17	CLIP-seq
MIRT869645	hsa-miR-1914	CLIP-seq
MIRT869646	hsa-miR-20a	CLIP-seq
MIRT869647	hsa-miR-20b	CLIP-seq
MIRT869648	hsa-miR-3177-5p	CLIP-seq
MIRT869649	hsa-miR-3609	CLIP-seq
MIRT869650	hsa-miR-3611	CLIP-seq
MIRT869651	hsa-miR-3653	CLIP-seq
MIRT869652	hsa-miR-3929	CLIP-seq
MIRT869653	hsa-miR-409-5p	CLIP-seq
MIRT869654	hsa-miR-4316	CLIP-seq
MIRT869655	hsa-miR-4419b	CLIP-seq
MIRT869656	hsa-miR-4427	CLIP-seq
MIRT869657	hsa-miR-4478	CLIP-seq
MIRT869658	hsa-miR-4710	CLIP-seq
MIRT869659	hsa-miR-4777-3p	CLIP-seq
MIRT869660	hsa-miR-4792	CLIP-seq
MIRT869661	hsa-miR-4796-3p	CLIP-seq
MIRT869662	hsa-miR-485-5p	CLIP-seq
MIRT869663	hsa-miR-513c	CLIP-seq
MIRT869664	hsa-miR-514b-5p	CLIP-seq
MIRT869665	hsa-miR-519d	CLIP-seq
MIRT869666	hsa-miR-548ah	CLIP-seq
MIRT869667	hsa-miR-548u	CLIP-seq
MIRT869668	hsa-miR-552	CLIP-seq
MIRT869669	hsa-miR-599	CLIP-seq
MIRT869670	hsa-miR-93	CLIP-seq
MIRT869671	hsa-miR-3161	CLIP-seq
MIRT869672	hsa-miR-3646	CLIP-seq
MIRT869652	hsa-miR-3929	CLIP-seq
MIRT869673	hsa-miR-3942-3p	CLIP-seq
MIRT869655	hsa-miR-4419b	CLIP-seq
MIRT869657	hsa-miR-4478	CLIP-seq
MIRT869674	hsa-miR-4760-5p	CLIP-seq
MIRT869675	hsa-miR-4775	CLIP-seq
MIRT2385665	hsa-miR-3607-3p	CLIP-seq
MIRT2385666	hsa-miR-3686	CLIP-seq
MIRT2385667	hsa-miR-4719	CLIP-seq
MIRT2385668	hsa-miR-4768-5p	CLIP-seq
MIRT2385669	hsa-miR-4797-3p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 28422092, 28514442, 31515488, 32296183
GO:0005622	Component	Intracellular anatomical structure	IBA	21873635
GO:0005737	Component	Cytoplasm	IEA
GO:0005814	Component	Centriole	IDA	28422092
GO:0008104	Process	Protein localization	IMP	28422092
GO:0034454	Process	Microtubule anchoring at centrosome	IGI	28422092
GO:0034454	Process	Microtubule anchoring at centrosome	IMP	28422092
GO:0035556	Process	Intracellular signal transduction	IBA	21873635
GO:0120103	Component	Centriolar subdistal appendage	IDA	28422092

MIM	HGNC	e!Ensembl
616909	24350	ENSG00000166510

Protein

UniProt ID

Q9H2F9

Protein name

Coiled-coil domain-containing protein 68 (Cutaneous T-cell lymphoma-associated antigen se57-1) (CTCL-associated antigen se57-1)

Protein function

Centriolar protein required for centriole subdistal appendage assembly and microtubule anchoring in interphase cells (PubMed:28422092). Together with CCDC120, cooperate with subdistal appendage components ODF2, NIN and CEP170 for hierarchical su

Family and domains

Tissue specificity

TISSUE SPECIFICITY: Expressed in bone marrow, colon, small intestine, spleen, testis, trachea and cutaneous T-cell lymphoma (CTCL). {ECO:0000269|PubMed:11149944, ECO:0000269|PubMed:15142679}.

Sequence

MTTVTVTTEIPPRDKMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDS
TNHKLDAKHCGNLQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASR
EAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEK
LEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATYGKSCQDLQREISILQ
EQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVA
LSSETPRTKVSKAVSTSELKTEGVSPYLMLIRLRK

Sequence length

335

Interactions

View interactions

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID	References
Causal
Narcolepsy	Narcolepsy	rs104894574, rs387906655	19629137
Schizophrenia	Schizophrenia	rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346 View all (12 more)	23439384

Show/Hide Unknown Diseases (5)

Disease term	Disease name	Evidence	Source
Unknown
Diabetes	Diabetes		GWAS
Neuroticism	Neuroticism		GWAS
Pancreatic cancer	Pancreatic cancer	Genome-Wide CRISPR Screening Identifies DCK and CCNL1 as Genes That Contribute to Gemcitabine Resistance in Pancreatic Cancer	GWAS, CBGDA
Mental Depression	Mental Depression		GWAS
Insomnia	Insomnia		GWAS

Show/Hide Text Mining Associations (2)

Disease Name	Relationship Type	References
Associations from Text Mining
Colorectal Neoplasms	Associate	19359472
Neoplasms	Inhibit	19359472

CCDC68 (coiled-coil domain containing 68)