Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
80315
Gene name Gene Name - the full gene name approved by the HGNC.
Cytoplasmic polyadenylation element binding protein 4
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CPEB4
Synonyms (NCBI Gene) Gene synonyms aliases
CPE-BP4, hCPEB-4
Chromosome Chromosome number
5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
5q35.2
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT005589 hsa-miR-26a-5p Luciferase reporter assay, Northern blot, qRT-PCR 20660482
MIRT005589 hsa-miR-26a-5p Luciferase reporter assay, Northern blot, qRT-PCR 20660482
MIRT005592 hsa-miR-29a-3p Luciferase reporter assay, Northern blot, qRT-PCR 20660482
MIRT005592 hsa-miR-29a-3p Luciferase reporter assay, Northern blot, qRT-PCR 20660482
MIRT005689 hsa-miR-145-5p Luciferase reporter assay 20737575
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000900 Function Translation repressor activity, mRNA regulatory element binding IBA 21873635
GO:0002931 Process Response to ischemia ISS
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0003730 Function MRNA 3'-UTR binding IBA 21873635
GO:0005515 Function Protein binding IPI 21336257
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
610607 21747 ENSG00000113742
Protein
UniProt ID Q17RY0
Protein name Cytoplasmic polyadenylation element-binding protein 4 (CPE-BP4) (CPE-binding protein 4) (hCPEB-4)
Protein function Sequence-specific RNA-binding protein that binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR (PubMed:24990967). RNA binding results in a clear confo
PDB 2MKI , 2MKJ , 5DIF
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF16367 RRM_7 471 560 RNA recognition motif Domain
PF16366 CEBP_ZZ 653 716 Cytoplasmic polyadenylation element-binding protein ZZ domain Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in pancreas in islets and ductal cells (at protein level) (PubMed:22138752). Expressed in melanocytes (PubMed:27857118). {ECO:0000269|PubMed:22138752, ECO:0000269|PubMed:27857118}.
Sequence
MGDYGFGVLVQSNTGNKSAFPVRFHPHLQPPHHHQNATPSPAAFINNNTAANGSSAGSAW
LFPAPATHNIQDEILGSEKAKSQQQEQQDPLEKQQLSPSPGQEAGILPETEKAKSEENQG
DNSSENGNGKEKIRIESPVLTGFDYQEATGLGTSTQPLTSSASSLTGFSNWSAAIAPSSS
TIINEDASFFHQGGVPAASANNGALLFQNFPHHVSPGFGGSFSPQIGPLSQHHPHHPHFQ
HHHSQHQQQRRSPASPHPPPFTHRNAAFNQLPHLANNLNKPPSPWSSYQSPSPTPSSSWS
PGGGGYGGWGGSQGRDHRRGLNGGITPLNSISPLKKNFASNHIQLQKYARPSSAFAPKSW
MEDSLNRADNIFPFPDRPRTFDMHSLESSLIDIMRAENDTIKGRLNYSYPGSDSSLLINA
RTYGRRRGQSSLFPMEDGFLDDGRGDQPLHSGLGSPHCFSHQNGERVERYSRKVFVGGLP
PDIDEDEITASFRRFGPLIVDWPHKAESKSYFPPKGYAFLLFQDESSVQALIDACIEEDG
KLYLCVSSPTIKDKPVQIRP
WNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIM
DRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGEIDKRVEVKPY
VLDDQLCDECQGARCGGKFAPFFCANVTCLQYYCEYCWAAIHSRAGREFHKPLVKE
GGDR
PRHISFRWN
Sequence length 729
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  Oocyte meiosis
Progesterone-mediated oocyte maturation
 
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Inflammatory bowel disease Inflammatory Bowel Diseases rs137853579, rs137853580, rs121909601, rs149491038, rs368287711, rs387907326, rs587777338, rs758439420, rs1329427406, rs1264862631, rs1192830343, rs1373354533, rs1419560997, rs1591263883, rs1989014468 26192919
Psoriasis Psoriasis rs281875215, rs587777763, rs281875213, rs281875212 26974007
Unknown
Disease term Disease name Evidence References Source
Crohn disease Crohn Disease 26974007, 26192919, 23128233 ClinVar
Crohn Disease Crohn Disease GWAS
Gout Gout GWAS
Atrial Fibrillation Atrial Fibrillation GWAS
Associations from Text Mining
Disease Name Relationship Type References
Astrocytoma Stimulate 26546435
Carcinoma Hepatocellular Inhibit 23145039
Carcinoma Non Small Cell Lung Inhibit 26209100
Carcinoma Non Small Cell Lung Associate 27113098, 27418131
Colorectal Neoplasms Associate 25339833, 25516661
Colorectal Neoplasms Inhibit 33237662
Colorectal Neoplasms Stimulate 37750623
Drug Related Side Effects and Adverse Reactions Associate 36919984
Exfoliative Ichthyosis Autosomal Recessive Ichthyosis Bullosa of Siemens like Associate 38490347
Gallbladder Neoplasms Associate 28060377