Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
8030
Gene name Gene Name - the full gene name approved by the HGNC.
Coiled-coil domain containing 6
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CCDC6
Synonyms (NCBI Gene) Gene synonyms aliases
D10S170, H4, PTC, PTC1, TPC, TST1
Chromosome Chromosome number
10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
10q21.2
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT021879 hsa-miR-128-3p Microarray 17612493
MIRT025091 hsa-miR-181a-5p Microarray 17612493
MIRT048991 hsa-miR-92a-3p CLASH 23622248
MIRT048602 hsa-miR-99a-5p CLASH 23622248
MIRT043723 hsa-miR-342-3p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005200 Function Structural constituent of cytoskeleton TAS 8058316
GO:0005515 Function Protein binding IPI 23108047, 28514442, 31980649, 32203420, 32296183
GO:0005829 Component Cytosol IDA
GO:0005856 Component Cytoskeleton IEA
GO:0007010 Process Cytoskeleton organization IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
601985 18782 ENSG00000108091
Protein
UniProt ID Q16204
Protein name Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF09755 DUF2046 42 337 Uncharacterized conserved protein H4 (DUF2046) Coiled-coil
Tissue specificity TISSUE SPECIFICITY: Ubiquitously expressed.
Sequence
Sequence length 474
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  Pathways in cancer
Thyroid cancer
 
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Leukemia Leukemia, Myelocytic, Acute rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297 27903959
Papillary thyroid carcinoma Papillary thyroid carcinoma rs751409106 28030816, 25407564
Thyroid cancer Familial Nonmedullary Thyroid Cancer rs119486096, rs104894171, rs28933406, rs11554290, rs121913364, rs797044990, rs1564566774, rs200989342 28030816
Associations from Text Mining
Disease Name Relationship Type References
Acute Disease Stimulate 29091592
Adenocarcinoma of Lung Associate 25567908, 34405544
Basal Cell Nevus Syndrome Associate 9140104
Carcinogenesis Associate 22655027
Carcinoma Neuroendocrine Associate 34245124
Carcinoma Non Small Cell Lung Associate 25384172, 33161056
Ciliary Motility Disorders Associate 34066907
Colorectal Neoplasms Associate 26078337, 36460334
Edema Associate 34666947
Epilepsy Associate 15805664