CCDC92 (coiled-coil domain containing 92)

Gene

• Entrez ID: 80212
• Gene name: Coiled-coil domain containing 92
• Gene symbol: CCDC92
• Synonyms (NCBI Gene): -
• Chromosome: 12
• Chromosome location: 12q24.31

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT019475	hsa-miR-148b-3p	Microarray	17612493
MIRT870445	hsa-miR-1250	CLIP-seq
MIRT870446	hsa-miR-2277-3p	CLIP-seq
MIRT870447	hsa-miR-2277-5p	CLIP-seq
MIRT870448	hsa-miR-3120-3p	CLIP-seq
MIRT870449	hsa-miR-3151	CLIP-seq
MIRT870450	hsa-miR-3153	CLIP-seq
MIRT870451	hsa-miR-3177-3p	CLIP-seq
MIRT870452	hsa-miR-3185	CLIP-seq
MIRT870453	hsa-miR-3187-3p	CLIP-seq
MIRT870454	hsa-miR-3611	CLIP-seq
MIRT870455	hsa-miR-3616-3p	CLIP-seq
MIRT870456	hsa-miR-3650	CLIP-seq
MIRT870457	hsa-miR-3689d	CLIP-seq
MIRT870458	hsa-miR-3925-3p	CLIP-seq
MIRT870459	hsa-miR-3974	CLIP-seq
MIRT870460	hsa-miR-423-3p	CLIP-seq
MIRT870461	hsa-miR-4292	CLIP-seq
MIRT870462	hsa-miR-4433	CLIP-seq
MIRT870463	hsa-miR-4435	CLIP-seq
MIRT870464	hsa-miR-4459	CLIP-seq
MIRT870465	hsa-miR-4496	CLIP-seq
MIRT870466	hsa-miR-4520a-3p	CLIP-seq
MIRT870467	hsa-miR-4632	CLIP-seq
MIRT870468	hsa-miR-4646-5p	CLIP-seq
MIRT870469	hsa-miR-4651	CLIP-seq
MIRT870470	hsa-miR-4668-5p	CLIP-seq
MIRT870471	hsa-miR-4701-5p	CLIP-seq
MIRT870472	hsa-miR-4761-5p	CLIP-seq
MIRT870473	hsa-miR-4768-3p	CLIP-seq
MIRT870474	hsa-miR-486-3p	CLIP-seq
MIRT870475	hsa-miR-502-5p	CLIP-seq
MIRT870476	hsa-miR-542-3p	CLIP-seq
MIRT870477	hsa-miR-548s	CLIP-seq
MIRT870478	hsa-miR-564	CLIP-seq
MIRT870479	hsa-miR-588	CLIP-seq
MIRT870480	hsa-miR-608	CLIP-seq
MIRT870481	hsa-miR-665	CLIP-seq
MIRT870482	hsa-miR-765	CLIP-seq
MIRT870483	hsa-miR-766	CLIP-seq
MIRT1958399	hsa-miR-146b-3p	CLIP-seq
MIRT1958400	hsa-miR-181a	CLIP-seq
MIRT1958401	hsa-miR-181b	CLIP-seq
MIRT1958402	hsa-miR-181c	CLIP-seq
MIRT1958403	hsa-miR-181d	CLIP-seq
MIRT1958404	hsa-miR-3173-5p	CLIP-seq
MIRT1958405	hsa-miR-3907	CLIP-seq
MIRT870460	hsa-miR-423-3p	CLIP-seq
MIRT1958406	hsa-miR-4254	CLIP-seq
MIRT1958407	hsa-miR-4262	CLIP-seq
MIRT1958408	hsa-miR-4308	CLIP-seq
MIRT1958409	hsa-miR-4689	CLIP-seq
MIRT1958410	hsa-miR-4755-3p	CLIP-seq
MIRT1958411	hsa-miR-580	CLIP-seq
MIRT1958412	hsa-miR-874	CLIP-seq
MIRT2195243	hsa-miR-1178	CLIP-seq
MIRT2195244	hsa-miR-1207-5p	CLIP-seq
MIRT2195245	hsa-miR-1279	CLIP-seq
MIRT2195246	hsa-miR-128	CLIP-seq
MIRT2195247	hsa-miR-148a	CLIP-seq
MIRT2195248	hsa-miR-148b	CLIP-seq
MIRT2195249	hsa-miR-152	CLIP-seq
MIRT1958400	hsa-miR-181a	CLIP-seq
MIRT1958401	hsa-miR-181b	CLIP-seq
MIRT1958402	hsa-miR-181c	CLIP-seq
MIRT1958403	hsa-miR-181d	CLIP-seq
MIRT2195250	hsa-miR-27a	CLIP-seq
MIRT2195251	hsa-miR-27b	CLIP-seq
MIRT2195252	hsa-miR-28-5p	CLIP-seq
MIRT2195253	hsa-miR-31	CLIP-seq
MIRT870448	hsa-miR-3120-3p	CLIP-seq
MIRT2195254	hsa-miR-3139	CLIP-seq
MIRT2195255	hsa-miR-3150b-3p	CLIP-seq
MIRT870452	hsa-miR-3185	CLIP-seq
MIRT870453	hsa-miR-3187-3p	CLIP-seq
MIRT870454	hsa-miR-3611	CLIP-seq
MIRT870455	hsa-miR-3616-3p	CLIP-seq
MIRT870456	hsa-miR-3650	CLIP-seq
MIRT870457	hsa-miR-3689d	CLIP-seq
MIRT2195256	hsa-miR-383	CLIP-seq
MIRT1958405	hsa-miR-3907	CLIP-seq
MIRT870458	hsa-miR-3925-3p	CLIP-seq
MIRT1958407	hsa-miR-4262	CLIP-seq
MIRT870463	hsa-miR-4435	CLIP-seq
MIRT870464	hsa-miR-4459	CLIP-seq
MIRT870465	hsa-miR-4496	CLIP-seq
MIRT2195257	hsa-miR-4504	CLIP-seq
MIRT2195258	hsa-miR-4517	CLIP-seq
MIRT1958409	hsa-miR-4689	CLIP-seq
MIRT870471	hsa-miR-4701-5p	CLIP-seq
MIRT2195259	hsa-miR-4734	CLIP-seq
MIRT2195260	hsa-miR-4763-3p	CLIP-seq
MIRT2195261	hsa-miR-4778-5p	CLIP-seq
MIRT2195262	hsa-miR-4784	CLIP-seq
MIRT870476	hsa-miR-542-3p	CLIP-seq
MIRT870477	hsa-miR-548s	CLIP-seq
MIRT870479	hsa-miR-588	CLIP-seq
MIRT870481	hsa-miR-665	CLIP-seq
MIRT2195263	hsa-miR-708	CLIP-seq
MIRT870482	hsa-miR-765	CLIP-seq
MIRT870483	hsa-miR-766	CLIP-seq
MIRT2498517	hsa-miR-1182	CLIP-seq
MIRT2498518	hsa-miR-1909	CLIP-seq
MIRT870458	hsa-miR-3925-3p	CLIP-seq
MIRT870460	hsa-miR-423-3p	CLIP-seq
MIRT2498519	hsa-miR-4419a	CLIP-seq
MIRT870464	hsa-miR-4459	CLIP-seq
MIRT2498520	hsa-miR-4510	CLIP-seq
MIRT1958410	hsa-miR-4755-3p	CLIP-seq
MIRT2498521	hsa-miR-4779	CLIP-seq
MIRT870481	hsa-miR-665	CLIP-seq
MIRT870483	hsa-miR-766	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	22458338, 22863007, 25416956, 28514442, 31515488, 32296183
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA
GO:0005814	Component	Centriole	IBA	21873635
GO:0005814	Component	Centriole	IDA	22863007
GO:0042802	Function	Identical protein binding	IPI	32296183
GO:0043231	Component	Intracellular membrane-bounded organelle	IDA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q53HC0
• Protein name: Coiled-coil domain-containing protein 92 (Limkain beta-2)
• Protein function: Interferon-stimulated protein that plays a role in innate immunity. Strongly inhibits ebolavirus transcription and replication. Forms a complex with viral RNA-bound nucleocapsid NP and thereby prevents the transport of NP to the cell surface. {E
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF14916	CCDC92	24 → 80	Coiled-coil domain of unknown function	Coiled-coil

• Sequence:

  MTSPHFSSYDEGPLDVSMAATNLENQLHSAQKNLLFLQREHASTLKGLHSEIRRLQQHCT
  DLTYELTVKSSEQTGDGTSKSSELKKRCEELEAQLKVKENENAELLKELEQKNAMITVLE
  NTIKEREKKYLEELKAKSHKLTLLSSELEQRASTIAYLTSQLHAAKKKLMSSSGTSDASP
  SGSPVLASYKPAPPKDKLPETPRRRMKKSLSAPLHPEFEEVYRFGAESRKLLLREPVDAM
  PDPTPFLLARESAEVHLIKERPLVIPPIASDRSGEQHSPAREKPHKAHVGVAHRIHHATP
  PQAQPEVKTLAVDQVNGGKVVRKHSGTDRTV

• Sequence length: 331

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Atrial fibrillation	Atrial Fibrillation	rs120074192, rs121908590, rs121908593, rs121434558, rs587776851, rs387906612, rs387906613, rs387906614, rs387906615, rs199472687, rs199472705, rs199473324, rs587777336, rs587777339, rs587777557, rs587777558, rs587777559, rs587777560, rs886037778, rs769405762, rs770372675	29892015
Coronary artery disease	Coronary Artery Disease	rs137852988, rs121918313, rs121918529, rs121918531, rs137852340, rs1555800701, rs1215189537	28714974, 29212778
Diabetes mellitus	Diabetes Mellitus, Non-Insulin-Dependent	rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs1362648752, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237, rs80356613, rs387906407, rs151344623, rs28938469, rs28936371, rs137852672, rs80356637, rs80356642, rs80356653, rs137852673, rs137852674, rs80356634, rs80356651, rs193929360, rs137853334, rs137853335, rs137853336, rs1600731198, rs137853338, rs121964882, rs121964883, rs387906511, rs121964884, rs121964885, rs2147483647, rs387906512, rs121964887, rs121964888, rs121964889, rs121964890, rs121964891, rs28934878, rs74315383, rs121964893, rs886037620, rs886037621, rs121434593, rs121913150, rs587776825, rs137853236, rs2135842335, rs137853237, rs137853238, rs2135818776, rs1566092470, rs1463923467, rs137853243, rs137853244, rs2135839114, rs137853245, rs2135847417, rs121918407, rs104894005, rs104894006, rs80356655, rs104894008, rs104894009, rs104894010, rs104894011, rs80356654, rs104894016, rs193929376, rs193929374, rs193929375, rs193929373, rs80356669, rs80356664, rs193929366, rs1048095, rs193929355, rs193929356, rs1259467443, rs104893642, rs387906777, rs193922396, rs193922400, rs193922401, rs137852676, rs193922407, rs193922638, rs193922257, rs193922258, rs193922259, rs193922260, rs193922261, rs193922262, rs193922263, rs193922264, rs193922265, rs193922268, rs193921338, rs193922269, rs193922272, rs193922273, rs193922275, rs193922278, rs193922279, rs193922280, rs193922281, rs193922282, rs193922283, rs193922284, rs193922286, rs193922287, rs193922289, rs193922291, rs193922295, rs193922297, rs193922300, rs193922302, rs193922303, rs193922308, rs193922313, rs193922314, rs144723656, rs193922315, rs193922316, rs193922317, rs148311934, rs193922319, rs193922320, rs193922326, rs193922329, rs193922330, rs193922331, rs193922335, rs193922336, rs193922338, rs193922340, rs193922341, rs193922471, rs193922475, rs193922476, rs193922479, rs80356663, rs193922355, rs193922356, rs193922576, rs193922578, rs193922582, rs193922588, rs193922592, rs193922594, rs193922596, rs386134267, rs193922598, rs193922599, rs193922600, rs193922604, rs193922605, rs397514580, rs397515519, rs267601516, rs587780343, rs587780345, rs587780346, rs587780347, rs587780357, rs148954387, rs587783672, rs587783669, rs786204676, rs794727236, rs151344624, rs794727775, rs794727839, rs199946797, rs869320673, rs796065047, rs759072800, rs797045595, rs797045209, rs797045207, rs797045213, rs863225280, rs149703259, rs864321656, rs139964066, rs777870079, rs878853246, rs769268803, rs886039380, rs886041392, rs886041391, rs886042610, rs143064649, rs1057516192, rs746480424, rs1057516281, rs576684889, rs754728827, rs1057520291, rs1057520779, rs893256143, rs1057520504, rs1057524790, rs1057524902, rs1057524904, rs1057524905, rs764232985, rs1064793998, rs1064794268, rs769086289, rs369429452, rs1085307913, rs1131691416, rs765432081, rs1131692182, rs748749585, rs1554335441, rs762263694, rs1312678560, rs767565869, rs1375656631, rs1554335391, rs1360415315, rs1554335616, rs1554335752, rs1554909277, rs769518471, rs757171524, rs768951263, rs762703502, rs1555212248, rs1555212359, rs1555813319, rs1555816654, rs371977235, rs1415041911, rs1554334894, rs1260178539, rs1554335421, rs1555211904, rs779184183, rs1554335564, rs200670692, rs1400535021, rs1554334872, rs1555212749, rs1553876668, rs1553878211, rs954727530, rs1554924035, rs372307320, rs925231098, rs1554913069, rs1554933565, rs766431403, rs746714109, rs751279984, rs770664202, rs1008906426, rs758844607, rs1554924540, rs1566092307, rs753998395, rs1565885935, rs1167124132, rs1376796469, rs556436603, rs1562715657, rs1486280029, rs1564869850, rs755259997, rs769569410, rs1172328722, rs1286294151, rs1375557127, rs1568731279, rs1562715426, rs556581174, rs1564865302, rs1565886545, rs1568724014, rs1392795567, rs781260712, rs1562719705, rs1382448285, rs1564977373, rs750586210, rs1598842892, rs1583592247, rs780612692, rs1593060859, rs1476637197, rs751279776, rs1593060890, rs1191912908, rs1167675604, rs1583601110, rs1593058932, rs778611627, rs753296261	28869590

Unknown
Disease term	Disease name	Evidence	References	Source
Coronary heart disease	Coronary heart disease		28869590	ClinVar
Atrial Fibrillation	Atrial Fibrillation			GWAS
Diabetes	Diabetes			GWAS
Metabolic Syndrome	Metabolic Syndrome			GWAS
Insomnia	Insomnia			GWAS
Myocardial Infarction	Myocardial Infarction			GWAS

Associations from Text Mining
Disease Name	Relationship Type	References
Colorectal Neoplasms	Associate	35785618
Coronary Artery Disease	Associate	28714974
Coronary Disease	Associate	28869590, 29439709
Diabetes Mellitus Type 2	Associate	28869590, 37540242
Hashimoto Disease	Associate	36674671
Hyperlipidemias	Associate	29439709
Insulin Resistance	Associate	28714974, 29439709
Stomach Neoplasms	Associate	34129933