TEDC2 (tubulin epsilon and delta complex 2)

Gene

• Entrez ID: 80178
• Gene name: Tubulin epsilon and delta complex 2
• Gene symbol: TEDC2
• Synonyms (NCBI Gene): C16orf59
• Chromosome: 16
• Chromosome location: 16p13.3

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 32296183, 33961781
GO:0005737	Component	Cytoplasm	IEA
GO:0005814	Component	Centriole	IEA
GO:0005814	Component	Centriole	ISS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005929	Component	Cilium	IEA
GO:0005929	Component	Cilium	ISS
GO:0042995	Component	Cell projection	IEA
GO:0045880	Process	Positive regulation of smoothened signaling pathway	IEA
GO:0045880	Process	Positive regulation of smoothened signaling pathway	ISS

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q7L2K0
• Protein name: Tubulin epsilon and delta complex protein 2
• Protein function: Acts as a positive regulator of ciliary hedgehog signaling. Required for centriole stability.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15764	DUF4693	148 → 431	Domain of unknown function (DUF4693)	Family

• Sequence:

  MLPAGCSRRLVAELQGALDACAQRQLQLEQSLRVCRRLLHAWEPTGTRALKPPPGPETNG
  EDPLPACTPSPQDLKELEFLTQALEKAVRVRRGITKAGERDKAPSLKSRSIVTSSGTTAS
  APPHSPGQAGGHASDTRPTKGLRQTTVPAKGHPERRLLSVGDGTRVGMGARTPRPGAGLR
  DQQMAPSAAPQAPEAFTLKEKGHLLRLPAAFRKAASQNSSLWAQLSSTQTSDSTDAAAAK
  TQFLQNMQTASGGPQPRLSAVEVEAEAGRLRKACSLLRLRMREELSAAPMDWMQEYRCLL
  TLEGLQAMVGQCLHRLQELRAAVAEQPPRPCPVGRPPGASPSCGGRAEPAWSPQLLVYSS
  TQELQTLAALKLRVAVLDQQIHLEKVLMAELLPLVSAAQPQGPPWLALCRAVHSLLCEGG
  ARVLTILRDEPAV

• Sequence length: 433