EDC3 (enhancer of mRNA decapping 3)

Gene

• Entrez ID: 80153
• Gene name: Enhancer of mRNA decapping 3
• Gene symbol: EDC3
• Synonyms (NCBI Gene): LSM16, MRT50, YJDC, YJEFN2, hYjeF_N2-15q23
• Chromosome: 15
• Chromosome location: 15q24.1
• Summary: This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5` to 3` mRNA decay pathway. Mutat

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs1057517676	A>G	Pathogenic	Genic upstream transcript variant, 5 prime UTR variant, coding sequence variant, missense variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020080	hsa-miR-361-5p	Sequencing	20371350
MIRT026990	hsa-miR-103a-3p	Sequencing	20371350
MIRT030653	hsa-miR-22-3p	Sequencing	20371350
MIRT031570	hsa-miR-16-5p	Sequencing	20371350
MIRT049900	hsa-miR-31-5p	CLASH	23622248
MIRT044648	hsa-miR-320a	CLASH	23622248
MIRT044189	hsa-miR-99b-5p	CLASH	23622248
MIRT043057	hsa-miR-324-5p	CLASH	23622248
MIRT039932	hsa-miR-615-3p	CLASH	23622248
MIRT037536	hsa-miR-744-5p	CLASH	23622248
MIRT036173	hsa-miR-320c	CLASH	23622248
MIRT727814	hsa-miR-15a-5p	HITS-CLIP	22473208
MIRT727813	hsa-miR-15b-5p	HITS-CLIP	22473208
MIRT031570	hsa-miR-16-5p	HITS-CLIP	22473208
MIRT727812	hsa-miR-195-5p	HITS-CLIP	22473208
MIRT727811	hsa-miR-30a-5p	HITS-CLIP	22473208
MIRT727810	hsa-miR-30b-5p	HITS-CLIP	22473208
MIRT727809	hsa-miR-30c-5p	HITS-CLIP	22473208
MIRT727808	hsa-miR-30d-5p	HITS-CLIP	22473208
MIRT727807	hsa-miR-30e-5p	HITS-CLIP	22473208
MIRT952107	hsa-miR-101	CLIP-seq
MIRT952108	hsa-miR-10a	CLIP-seq
MIRT952109	hsa-miR-10b	CLIP-seq
MIRT952110	hsa-miR-1207-5p	CLIP-seq
MIRT952111	hsa-miR-1224-3p	CLIP-seq
MIRT952112	hsa-miR-1254	CLIP-seq
MIRT952113	hsa-miR-1255a	CLIP-seq
MIRT952114	hsa-miR-1255b	CLIP-seq
MIRT952115	hsa-miR-1263	CLIP-seq
MIRT952116	hsa-miR-127-5p	CLIP-seq
MIRT952117	hsa-miR-1304	CLIP-seq
MIRT952118	hsa-miR-1324	CLIP-seq
MIRT952119	hsa-miR-138	CLIP-seq
MIRT952120	hsa-miR-144	CLIP-seq
MIRT952121	hsa-miR-147b	CLIP-seq
MIRT952122	hsa-miR-148a	CLIP-seq
MIRT952123	hsa-miR-148b	CLIP-seq
MIRT952124	hsa-miR-149	CLIP-seq
MIRT952125	hsa-miR-152	CLIP-seq
MIRT952126	hsa-miR-15a	CLIP-seq
MIRT952127	hsa-miR-15b	CLIP-seq
MIRT952128	hsa-miR-16	CLIP-seq
MIRT952129	hsa-miR-1825	CLIP-seq
MIRT952130	hsa-miR-1909	CLIP-seq
MIRT952131	hsa-miR-195	CLIP-seq
MIRT952132	hsa-miR-1973	CLIP-seq
MIRT952133	hsa-miR-2110	CLIP-seq
MIRT952134	hsa-miR-2117	CLIP-seq
MIRT952135	hsa-miR-214	CLIP-seq
MIRT952136	hsa-miR-22	CLIP-seq
MIRT952137	hsa-miR-223	CLIP-seq
MIRT952138	hsa-miR-2278	CLIP-seq
MIRT952139	hsa-miR-24	CLIP-seq
MIRT952140	hsa-miR-2467-3p	CLIP-seq
MIRT952141	hsa-miR-297	CLIP-seq
MIRT952142	hsa-miR-3064-5p	CLIP-seq
MIRT952143	hsa-miR-30a	CLIP-seq
MIRT952144	hsa-miR-30b	CLIP-seq
MIRT952145	hsa-miR-30c	CLIP-seq
MIRT952146	hsa-miR-30d	CLIP-seq
MIRT952147	hsa-miR-30e	CLIP-seq
MIRT952148	hsa-miR-3116	CLIP-seq
MIRT952149	hsa-miR-3121-3p	CLIP-seq
MIRT952150	hsa-miR-3125	CLIP-seq
MIRT952151	hsa-miR-3127-3p	CLIP-seq
MIRT952152	hsa-miR-3127-5p	CLIP-seq
MIRT952153	hsa-miR-3132	CLIP-seq
MIRT952154	hsa-miR-3134	CLIP-seq
MIRT952155	hsa-miR-3136-3p	CLIP-seq
MIRT952156	hsa-miR-3151	CLIP-seq
MIRT952157	hsa-miR-3162-3p	CLIP-seq
MIRT952158	hsa-miR-3176	CLIP-seq
MIRT952159	hsa-miR-3180	CLIP-seq
MIRT952160	hsa-miR-3180-3p	CLIP-seq
MIRT952161	hsa-miR-3184	CLIP-seq
MIRT952162	hsa-miR-3194-5p	CLIP-seq
MIRT952163	hsa-miR-3196	CLIP-seq
MIRT952164	hsa-miR-3202	CLIP-seq
MIRT952165	hsa-miR-323b-3p	CLIP-seq
MIRT952166	hsa-miR-326	CLIP-seq
MIRT952167	hsa-miR-330-5p	CLIP-seq
MIRT952168	hsa-miR-342-3p	CLIP-seq
MIRT952169	hsa-miR-3591-3p	CLIP-seq
MIRT952170	hsa-miR-3607-3p	CLIP-seq
MIRT952171	hsa-miR-361-3p	CLIP-seq
MIRT952172	hsa-miR-3616-3p	CLIP-seq
MIRT952173	hsa-miR-3619-5p	CLIP-seq
MIRT952174	hsa-miR-362-5p	CLIP-seq
MIRT952175	hsa-miR-365	CLIP-seq
MIRT952176	hsa-miR-3661	CLIP-seq
MIRT952177	hsa-miR-3682-5p	CLIP-seq
MIRT952178	hsa-miR-3685	CLIP-seq
MIRT952179	hsa-miR-371b-3p	CLIP-seq
MIRT952180	hsa-miR-374c	CLIP-seq
MIRT952181	hsa-miR-3916	CLIP-seq
MIRT952182	hsa-miR-3918	CLIP-seq
MIRT952183	hsa-miR-3921	CLIP-seq
MIRT952184	hsa-miR-3922-3p	CLIP-seq
MIRT952185	hsa-miR-423-5p	CLIP-seq
MIRT952186	hsa-miR-424	CLIP-seq
MIRT952187	hsa-miR-4253	CLIP-seq
MIRT952188	hsa-miR-4254	CLIP-seq
MIRT952189	hsa-miR-4271	CLIP-seq
MIRT952190	hsa-miR-4273	CLIP-seq
MIRT952191	hsa-miR-4276	CLIP-seq
MIRT952192	hsa-miR-4284	CLIP-seq
MIRT952193	hsa-miR-4292	CLIP-seq
MIRT952194	hsa-miR-4308	CLIP-seq
MIRT952195	hsa-miR-4313	CLIP-seq
MIRT952196	hsa-miR-4326	CLIP-seq
MIRT952197	hsa-miR-4328	CLIP-seq
MIRT952198	hsa-miR-4433	CLIP-seq
MIRT952199	hsa-miR-4436b-3p	CLIP-seq
MIRT952200	hsa-miR-4438	CLIP-seq
MIRT952201	hsa-miR-4447	CLIP-seq
MIRT952202	hsa-miR-4451	CLIP-seq
MIRT952203	hsa-miR-4459	CLIP-seq
MIRT952204	hsa-miR-4472	CLIP-seq
MIRT952205	hsa-miR-4488	CLIP-seq
MIRT952206	hsa-miR-4493	CLIP-seq
MIRT952207	hsa-miR-4512	CLIP-seq
MIRT952208	hsa-miR-4521	CLIP-seq
MIRT952209	hsa-miR-4534	CLIP-seq
MIRT952210	hsa-miR-455-5p	CLIP-seq
MIRT952211	hsa-miR-4632	CLIP-seq
MIRT952212	hsa-miR-4640-5p	CLIP-seq
MIRT952213	hsa-miR-4652-3p	CLIP-seq
MIRT952214	hsa-miR-4653-3p	CLIP-seq
MIRT952215	hsa-miR-4653-5p	CLIP-seq
MIRT952216	hsa-miR-4656	CLIP-seq
MIRT952217	hsa-miR-4667-5p	CLIP-seq
MIRT952218	hsa-miR-4682	CLIP-seq
MIRT952219	hsa-miR-4685-5p	CLIP-seq
MIRT952220	hsa-miR-4686	CLIP-seq
MIRT952221	hsa-miR-4687-5p	CLIP-seq
MIRT952222	hsa-miR-4697-5p	CLIP-seq
MIRT952223	hsa-miR-4700-3p	CLIP-seq
MIRT952224	hsa-miR-4700-5p	CLIP-seq
MIRT952225	hsa-miR-4704-3p	CLIP-seq
MIRT952226	hsa-miR-4708-5p	CLIP-seq
MIRT952227	hsa-miR-4714-3p	CLIP-seq
MIRT952228	hsa-miR-4721	CLIP-seq
MIRT952229	hsa-miR-4725-3p	CLIP-seq
MIRT952230	hsa-miR-4726-5p	CLIP-seq
MIRT952231	hsa-miR-4747-5p	CLIP-seq
MIRT952232	hsa-miR-4753-3p	CLIP-seq
MIRT952233	hsa-miR-4763-3p	CLIP-seq
MIRT952234	hsa-miR-4765	CLIP-seq
MIRT952235	hsa-miR-4766-5p	CLIP-seq
MIRT952236	hsa-miR-4767	CLIP-seq
MIRT952237	hsa-miR-4768-3p	CLIP-seq
MIRT952238	hsa-miR-4768-5p	CLIP-seq
MIRT952239	hsa-miR-4794	CLIP-seq
MIRT952240	hsa-miR-4802-5p	CLIP-seq
MIRT952241	hsa-miR-4803	CLIP-seq
MIRT952242	hsa-miR-486-3p	CLIP-seq
MIRT952243	hsa-miR-487a	CLIP-seq
MIRT952244	hsa-miR-492	CLIP-seq
MIRT952245	hsa-miR-497	CLIP-seq
MIRT952246	hsa-miR-500b	CLIP-seq
MIRT952247	hsa-miR-501-5p	CLIP-seq
MIRT952248	hsa-miR-5095	CLIP-seq
MIRT952249	hsa-miR-512-3p	CLIP-seq
MIRT952250	hsa-miR-518a-5p	CLIP-seq
MIRT952251	hsa-miR-524-3p	CLIP-seq
MIRT952252	hsa-miR-525-3p	CLIP-seq
MIRT952253	hsa-miR-526b	CLIP-seq
MIRT952254	hsa-miR-527	CLIP-seq
MIRT952255	hsa-miR-542-3p	CLIP-seq
MIRT952256	hsa-miR-558	CLIP-seq
MIRT952257	hsa-miR-567	CLIP-seq
MIRT952258	hsa-miR-624	CLIP-seq
MIRT952259	hsa-miR-631	CLIP-seq
MIRT952260	hsa-miR-637	CLIP-seq
MIRT952261	hsa-miR-655	CLIP-seq
MIRT952262	hsa-miR-659	CLIP-seq
MIRT952263	hsa-miR-661	CLIP-seq
MIRT952264	hsa-miR-670	CLIP-seq
MIRT952265	hsa-miR-761	CLIP-seq
MIRT952266	hsa-miR-767-3p	CLIP-seq
MIRT952267	hsa-miR-802	CLIP-seq
MIRT952268	hsa-miR-875-5p	CLIP-seq
MIRT952269	hsa-miR-922	CLIP-seq
MIRT952270	hsa-miR-942	CLIP-seq
MIRT1548152	hsa-miR-2277-3p	CLIP-seq
MIRT952119	hsa-miR-138	CLIP-seq
MIRT952122	hsa-miR-148a	CLIP-seq
MIRT952123	hsa-miR-148b	CLIP-seq
MIRT952125	hsa-miR-152	CLIP-seq
MIRT952126	hsa-miR-15a	CLIP-seq
MIRT952127	hsa-miR-15b	CLIP-seq
MIRT952128	hsa-miR-16	CLIP-seq
MIRT1981952	hsa-miR-185	CLIP-seq
MIRT952130	hsa-miR-1909	CLIP-seq
MIRT1981953	hsa-miR-1913	CLIP-seq
MIRT952131	hsa-miR-195	CLIP-seq
MIRT952133	hsa-miR-2110	CLIP-seq
MIRT952135	hsa-miR-214	CLIP-seq
MIRT952136	hsa-miR-22	CLIP-seq
MIRT1981954	hsa-miR-3138	CLIP-seq
MIRT1981955	hsa-miR-3153	CLIP-seq
MIRT1981956	hsa-miR-3165	CLIP-seq
MIRT1981957	hsa-miR-324-3p	CLIP-seq
MIRT952166	hsa-miR-326	CLIP-seq
MIRT952167	hsa-miR-330-5p	CLIP-seq
MIRT1981958	hsa-miR-337-3p	CLIP-seq
MIRT1981959	hsa-miR-346	CLIP-seq
MIRT952173	hsa-miR-3619-5p	CLIP-seq
MIRT1981960	hsa-miR-3665	CLIP-seq
MIRT1981961	hsa-miR-3690	CLIP-seq
MIRT952186	hsa-miR-424	CLIP-seq
MIRT952189	hsa-miR-4271	CLIP-seq
MIRT952191	hsa-miR-4276	CLIP-seq
MIRT1981962	hsa-miR-4290	CLIP-seq
MIRT1981963	hsa-miR-4299	CLIP-seq
MIRT1981964	hsa-miR-4302	CLIP-seq
MIRT1981965	hsa-miR-4306	CLIP-seq
MIRT952194	hsa-miR-4308	CLIP-seq
MIRT952196	hsa-miR-4326	CLIP-seq
MIRT952198	hsa-miR-4433	CLIP-seq
MIRT1981966	hsa-miR-4456	CLIP-seq
MIRT952203	hsa-miR-4459	CLIP-seq
MIRT952206	hsa-miR-4493	CLIP-seq
MIRT1981967	hsa-miR-4527	CLIP-seq
MIRT1981968	hsa-miR-4638-3p	CLIP-seq
MIRT1981969	hsa-miR-4644	CLIP-seq
MIRT952217	hsa-miR-4667-5p	CLIP-seq
MIRT1981970	hsa-miR-4693-3p	CLIP-seq
MIRT952224	hsa-miR-4700-5p	CLIP-seq
MIRT952225	hsa-miR-4704-3p	CLIP-seq
MIRT1981971	hsa-miR-4711-5p	CLIP-seq
MIRT1981972	hsa-miR-4722-3p	CLIP-seq
MIRT952229	hsa-miR-4725-3p	CLIP-seq
MIRT952231	hsa-miR-4747-5p	CLIP-seq
MIRT952237	hsa-miR-4768-3p	CLIP-seq
MIRT1981973	hsa-miR-4790-3p	CLIP-seq
MIRT952245	hsa-miR-497	CLIP-seq
MIRT952249	hsa-miR-512-3p	CLIP-seq
MIRT1981974	hsa-miR-548a-3p	CLIP-seq
MIRT1981975	hsa-miR-548e	CLIP-seq
MIRT1981976	hsa-miR-548f	CLIP-seq
MIRT1981977	hsa-miR-548q	CLIP-seq
MIRT1981978	hsa-miR-584	CLIP-seq
MIRT952260	hsa-miR-637	CLIP-seq
MIRT1981979	hsa-miR-657	CLIP-seq
MIRT952265	hsa-miR-761	CLIP-seq
MIRT952268	hsa-miR-875-5p	CLIP-seq
MIRT952269	hsa-miR-922	CLIP-seq
MIRT952107	hsa-miR-101	CLIP-seq
MIRT952111	hsa-miR-1224-3p	CLIP-seq
MIRT2216848	hsa-miR-1253	CLIP-seq
MIRT952120	hsa-miR-144	CLIP-seq
MIRT952126	hsa-miR-15a	CLIP-seq
MIRT952127	hsa-miR-15b	CLIP-seq
MIRT952128	hsa-miR-16	CLIP-seq
MIRT952129	hsa-miR-1825	CLIP-seq
MIRT1981952	hsa-miR-185	CLIP-seq
MIRT952130	hsa-miR-1909	CLIP-seq
MIRT952131	hsa-miR-195	CLIP-seq
MIRT952135	hsa-miR-214	CLIP-seq
MIRT952136	hsa-miR-22	CLIP-seq
MIRT952138	hsa-miR-2278	CLIP-seq
MIRT952139	hsa-miR-24	CLIP-seq
MIRT2216849	hsa-miR-2467-5p	CLIP-seq
MIRT952143	hsa-miR-30a	CLIP-seq
MIRT952144	hsa-miR-30b	CLIP-seq
MIRT952145	hsa-miR-30c	CLIP-seq
MIRT952146	hsa-miR-30d	CLIP-seq
MIRT952147	hsa-miR-30e	CLIP-seq
MIRT2216850	hsa-miR-3123	CLIP-seq
MIRT2216851	hsa-miR-3148	CLIP-seq
MIRT2216852	hsa-miR-3150a-3p	CLIP-seq
MIRT1981955	hsa-miR-3153	CLIP-seq
MIRT2216853	hsa-miR-3175	CLIP-seq
MIRT2216854	hsa-miR-3189-3p	CLIP-seq
MIRT2216855	hsa-miR-331-3p	CLIP-seq
MIRT952170	hsa-miR-3607-3p	CLIP-seq
MIRT952171	hsa-miR-361-3p	CLIP-seq
MIRT952173	hsa-miR-3619-5p	CLIP-seq
MIRT952174	hsa-miR-362-5p	CLIP-seq
MIRT952175	hsa-miR-365	CLIP-seq
MIRT1981961	hsa-miR-3690	CLIP-seq
MIRT952179	hsa-miR-371b-3p	CLIP-seq
MIRT2216856	hsa-miR-3919	CLIP-seq
MIRT2216857	hsa-miR-3978	CLIP-seq
MIRT952186	hsa-miR-424	CLIP-seq
MIRT952193	hsa-miR-4292	CLIP-seq
MIRT1981965	hsa-miR-4306	CLIP-seq
MIRT952194	hsa-miR-4308	CLIP-seq
MIRT2216858	hsa-miR-4310	CLIP-seq
MIRT952195	hsa-miR-4313	CLIP-seq
MIRT2216859	hsa-miR-4419a	CLIP-seq
MIRT952198	hsa-miR-4433	CLIP-seq
MIRT952203	hsa-miR-4459	CLIP-seq
MIRT2216860	hsa-miR-4468	CLIP-seq
MIRT2216861	hsa-miR-4510	CLIP-seq
MIRT1981967	hsa-miR-4527	CLIP-seq
MIRT1981968	hsa-miR-4638-3p	CLIP-seq
MIRT1981969	hsa-miR-4644	CLIP-seq
MIRT952217	hsa-miR-4667-5p	CLIP-seq
MIRT2216862	hsa-miR-4672	CLIP-seq
MIRT952224	hsa-miR-4700-5p	CLIP-seq
MIRT2216863	hsa-miR-4715-3p	CLIP-seq
MIRT1981972	hsa-miR-4722-3p	CLIP-seq
MIRT2216864	hsa-miR-4756-3p	CLIP-seq
MIRT952237	hsa-miR-4768-3p	CLIP-seq
MIRT952245	hsa-miR-497	CLIP-seq
MIRT952246	hsa-miR-500b	CLIP-seq
MIRT952247	hsa-miR-501-5p	CLIP-seq
MIRT952251	hsa-miR-524-3p	CLIP-seq
MIRT952252	hsa-miR-525-3p	CLIP-seq
MIRT952253	hsa-miR-526b	CLIP-seq
MIRT1981974	hsa-miR-548a-3p	CLIP-seq
MIRT2216865	hsa-miR-548c-3p	CLIP-seq
MIRT1981975	hsa-miR-548e	CLIP-seq
MIRT1981976	hsa-miR-548f	CLIP-seq
MIRT952256	hsa-miR-558	CLIP-seq
MIRT952265	hsa-miR-761	CLIP-seq
MIRT2216866	hsa-miR-890	CLIP-seq
MIRT952269	hsa-miR-922	CLIP-seq
MIRT2216867	hsa-miR-939	CLIP-seq
MIRT2387209	hsa-miR-1226	CLIP-seq
MIRT1981958	hsa-miR-337-3p	CLIP-seq
MIRT1981964	hsa-miR-4302	CLIP-seq
MIRT952196	hsa-miR-4326	CLIP-seq
MIRT1981971	hsa-miR-4711-5p	CLIP-seq
MIRT1981978	hsa-miR-584	CLIP-seq
MIRT952136	hsa-miR-22	CLIP-seq
MIRT1981955	hsa-miR-3153	CLIP-seq
MIRT2520857	hsa-miR-1207-3p	CLIP-seq
MIRT952111	hsa-miR-1224-3p	CLIP-seq
MIRT2520858	hsa-miR-1225-3p	CLIP-seq
MIRT2520859	hsa-miR-1233	CLIP-seq
MIRT2520860	hsa-miR-1237	CLIP-seq
MIRT2520861	hsa-miR-1245b-3p	CLIP-seq
MIRT952112	hsa-miR-1254	CLIP-seq
MIRT952115	hsa-miR-1263	CLIP-seq
MIRT2520862	hsa-miR-1285	CLIP-seq
MIRT2520863	hsa-miR-129-3p	CLIP-seq
MIRT2520864	hsa-miR-1301	CLIP-seq
MIRT2520865	hsa-miR-139-5p	CLIP-seq
MIRT2520866	hsa-miR-151-3p	CLIP-seq
MIRT1981952	hsa-miR-185	CLIP-seq
MIRT952130	hsa-miR-1909	CLIP-seq
MIRT1981953	hsa-miR-1913	CLIP-seq
MIRT952132	hsa-miR-1973	CLIP-seq
MIRT952133	hsa-miR-2110	CLIP-seq
MIRT952134	hsa-miR-2117	CLIP-seq
MIRT952136	hsa-miR-22	CLIP-seq
MIRT952137	hsa-miR-223	CLIP-seq
MIRT952143	hsa-miR-30a	CLIP-seq
MIRT952144	hsa-miR-30b	CLIP-seq
MIRT952145	hsa-miR-30c	CLIP-seq
MIRT952146	hsa-miR-30d	CLIP-seq
MIRT952147	hsa-miR-30e	CLIP-seq
MIRT952148	hsa-miR-3116	CLIP-seq
MIRT2520867	hsa-miR-3120-5p	CLIP-seq
MIRT952150	hsa-miR-3125	CLIP-seq
MIRT2520868	hsa-miR-3130-5p	CLIP-seq
MIRT952153	hsa-miR-3132	CLIP-seq
MIRT1981954	hsa-miR-3138	CLIP-seq
MIRT1981955	hsa-miR-3153	CLIP-seq
MIRT2520869	hsa-miR-3157-5p	CLIP-seq
MIRT1981956	hsa-miR-3165	CLIP-seq
MIRT2520870	hsa-miR-3171	CLIP-seq
MIRT2520871	hsa-miR-3182	CLIP-seq
MIRT2520872	hsa-miR-3187-5p	CLIP-seq
MIRT2216854	hsa-miR-3189-3p	CLIP-seq
MIRT952162	hsa-miR-3194-5p	CLIP-seq
MIRT952164	hsa-miR-3202	CLIP-seq
MIRT1981957	hsa-miR-324-3p	CLIP-seq
MIRT2520873	hsa-miR-330-3p	CLIP-seq
MIRT952168	hsa-miR-342-3p	CLIP-seq
MIRT2520874	hsa-miR-342-5p	CLIP-seq
MIRT1981959	hsa-miR-346	CLIP-seq
MIRT952170	hsa-miR-3607-3p	CLIP-seq
MIRT952174	hsa-miR-362-5p	CLIP-seq
MIRT2520875	hsa-miR-3654	CLIP-seq
MIRT1981960	hsa-miR-3665	CLIP-seq
MIRT2520876	hsa-miR-3670	CLIP-seq
MIRT1981961	hsa-miR-3690	CLIP-seq
MIRT952181	hsa-miR-3916	CLIP-seq
MIRT952182	hsa-miR-3918	CLIP-seq
MIRT2520877	hsa-miR-3940-3p	CLIP-seq
MIRT2520878	hsa-miR-3944-5p	CLIP-seq
MIRT952188	hsa-miR-4254	CLIP-seq
MIRT952189	hsa-miR-4271	CLIP-seq
MIRT952190	hsa-miR-4273	CLIP-seq
MIRT2520879	hsa-miR-4288	CLIP-seq
MIRT1981962	hsa-miR-4290	CLIP-seq
MIRT952193	hsa-miR-4292	CLIP-seq
MIRT1981963	hsa-miR-4299	CLIP-seq
MIRT2520880	hsa-miR-4305	CLIP-seq
MIRT1981965	hsa-miR-4306	CLIP-seq
MIRT952194	hsa-miR-4308	CLIP-seq
MIRT952197	hsa-miR-4328	CLIP-seq
MIRT2520881	hsa-miR-4446-3p	CLIP-seq
MIRT952202	hsa-miR-4451	CLIP-seq
MIRT1981966	hsa-miR-4456	CLIP-seq
MIRT2520882	hsa-miR-4463	CLIP-seq
MIRT2520883	hsa-miR-4476	CLIP-seq
MIRT2520884	hsa-miR-4482	CLIP-seq
MIRT2520885	hsa-miR-4487	CLIP-seq
MIRT2520886	hsa-miR-4495	CLIP-seq
MIRT2520887	hsa-miR-4499	CLIP-seq
MIRT952207	hsa-miR-4512	CLIP-seq
MIRT2520888	hsa-miR-4520a-3p	CLIP-seq
MIRT2520889	hsa-miR-4520a-5p	CLIP-seq
MIRT2520890	hsa-miR-4520b-5p	CLIP-seq
MIRT1981967	hsa-miR-4527	CLIP-seq
MIRT2520891	hsa-miR-4633-3p	CLIP-seq
MIRT1981968	hsa-miR-4638-3p	CLIP-seq
MIRT1981969	hsa-miR-4644	CLIP-seq
MIRT2520892	hsa-miR-4651	CLIP-seq
MIRT952213	hsa-miR-4652-3p	CLIP-seq
MIRT952214	hsa-miR-4653-3p	CLIP-seq
MIRT952216	hsa-miR-4656	CLIP-seq
MIRT2520893	hsa-miR-4660	CLIP-seq
MIRT2520894	hsa-miR-4664-5p	CLIP-seq
MIRT2520895	hsa-miR-4668-5p	CLIP-seq
MIRT2520896	hsa-miR-4675	CLIP-seq
MIRT952219	hsa-miR-4685-5p	CLIP-seq
MIRT2520897	hsa-miR-4691-3p	CLIP-seq
MIRT1981970	hsa-miR-4693-3p	CLIP-seq
MIRT952226	hsa-miR-4708-5p	CLIP-seq
MIRT2520898	hsa-miR-4710	CLIP-seq
MIRT2216863	hsa-miR-4715-3p	CLIP-seq
MIRT952229	hsa-miR-4725-3p	CLIP-seq
MIRT2520899	hsa-miR-4731-5p	CLIP-seq
MIRT2520900	hsa-miR-4741	CLIP-seq
MIRT952238	hsa-miR-4768-5p	CLIP-seq
MIRT1981973	hsa-miR-4790-3p	CLIP-seq
MIRT2520901	hsa-miR-4792	CLIP-seq
MIRT952239	hsa-miR-4794	CLIP-seq
MIRT2520902	hsa-miR-4797-5p	CLIP-seq
MIRT2520903	hsa-miR-491-5p	CLIP-seq
MIRT2520904	hsa-miR-494	CLIP-seq
MIRT2520905	hsa-miR-495	CLIP-seq
MIRT2520906	hsa-miR-500a	CLIP-seq
MIRT952246	hsa-miR-500b	CLIP-seq
MIRT2520907	hsa-miR-5047	CLIP-seq
MIRT952253	hsa-miR-526b	CLIP-seq
MIRT952255	hsa-miR-542-3p	CLIP-seq
MIRT1981977	hsa-miR-548q	CLIP-seq
MIRT2520908	hsa-miR-548u	CLIP-seq
MIRT952256	hsa-miR-558	CLIP-seq
MIRT2520909	hsa-miR-608	CLIP-seq
MIRT2520910	hsa-miR-612	CLIP-seq
MIRT2520911	hsa-miR-617	CLIP-seq
MIRT2520912	hsa-miR-626	CLIP-seq
MIRT2520913	hsa-miR-632	CLIP-seq
MIRT1981979	hsa-miR-657	CLIP-seq
MIRT952263	hsa-miR-661	CLIP-seq
MIRT952264	hsa-miR-670	CLIP-seq
MIRT2520857	hsa-miR-1207-3p	CLIP-seq
MIRT952111	hsa-miR-1224-3p	CLIP-seq
MIRT2520858	hsa-miR-1225-3p	CLIP-seq
MIRT2520859	hsa-miR-1233	CLIP-seq
MIRT2520860	hsa-miR-1237	CLIP-seq
MIRT2520861	hsa-miR-1245b-3p	CLIP-seq
MIRT952112	hsa-miR-1254	CLIP-seq
MIRT952115	hsa-miR-1263	CLIP-seq
MIRT2520863	hsa-miR-129-3p	CLIP-seq
MIRT2520864	hsa-miR-1301	CLIP-seq
MIRT2520865	hsa-miR-139-5p	CLIP-seq
MIRT2520866	hsa-miR-151-3p	CLIP-seq
MIRT1981952	hsa-miR-185	CLIP-seq
MIRT952130	hsa-miR-1909	CLIP-seq
MIRT1981953	hsa-miR-1913	CLIP-seq
MIRT952132	hsa-miR-1973	CLIP-seq
MIRT952133	hsa-miR-2110	CLIP-seq
MIRT952134	hsa-miR-2117	CLIP-seq
MIRT952136	hsa-miR-22	CLIP-seq
MIRT952137	hsa-miR-223	CLIP-seq
MIRT952143	hsa-miR-30a	CLIP-seq
MIRT952144	hsa-miR-30b	CLIP-seq
MIRT952145	hsa-miR-30c	CLIP-seq
MIRT952146	hsa-miR-30d	CLIP-seq
MIRT952147	hsa-miR-30e	CLIP-seq
MIRT952148	hsa-miR-3116	CLIP-seq
MIRT2520867	hsa-miR-3120-5p	CLIP-seq
MIRT952150	hsa-miR-3125	CLIP-seq
MIRT2520868	hsa-miR-3130-5p	CLIP-seq
MIRT952153	hsa-miR-3132	CLIP-seq
MIRT1981954	hsa-miR-3138	CLIP-seq
MIRT1981955	hsa-miR-3153	CLIP-seq
MIRT2520869	hsa-miR-3157-5p	CLIP-seq
MIRT1981956	hsa-miR-3165	CLIP-seq
MIRT2520870	hsa-miR-3171	CLIP-seq
MIRT2520871	hsa-miR-3182	CLIP-seq
MIRT2216854	hsa-miR-3189-3p	CLIP-seq
MIRT952162	hsa-miR-3194-5p	CLIP-seq
MIRT952164	hsa-miR-3202	CLIP-seq
MIRT1981957	hsa-miR-324-3p	CLIP-seq
MIRT2520873	hsa-miR-330-3p	CLIP-seq
MIRT952168	hsa-miR-342-3p	CLIP-seq
MIRT2520874	hsa-miR-342-5p	CLIP-seq
MIRT1981959	hsa-miR-346	CLIP-seq
MIRT952170	hsa-miR-3607-3p	CLIP-seq
MIRT952174	hsa-miR-362-5p	CLIP-seq
MIRT2520875	hsa-miR-3654	CLIP-seq
MIRT1981960	hsa-miR-3665	CLIP-seq
MIRT2520876	hsa-miR-3670	CLIP-seq
MIRT1981961	hsa-miR-3690	CLIP-seq
MIRT952181	hsa-miR-3916	CLIP-seq
MIRT952182	hsa-miR-3918	CLIP-seq
MIRT2520877	hsa-miR-3940-3p	CLIP-seq
MIRT2520878	hsa-miR-3944-5p	CLIP-seq
MIRT952189	hsa-miR-4271	CLIP-seq
MIRT952190	hsa-miR-4273	CLIP-seq
MIRT2520879	hsa-miR-4288	CLIP-seq
MIRT1981962	hsa-miR-4290	CLIP-seq
MIRT952193	hsa-miR-4292	CLIP-seq
MIRT1981963	hsa-miR-4299	CLIP-seq
MIRT2520880	hsa-miR-4305	CLIP-seq
MIRT1981965	hsa-miR-4306	CLIP-seq
MIRT952194	hsa-miR-4308	CLIP-seq
MIRT2679750	hsa-miR-4311	CLIP-seq
MIRT952197	hsa-miR-4328	CLIP-seq
MIRT2520881	hsa-miR-4446-3p	CLIP-seq
MIRT952202	hsa-miR-4451	CLIP-seq
MIRT1981966	hsa-miR-4456	CLIP-seq
MIRT2520882	hsa-miR-4463	CLIP-seq
MIRT2520883	hsa-miR-4476	CLIP-seq
MIRT2520884	hsa-miR-4482	CLIP-seq
MIRT2520885	hsa-miR-4487	CLIP-seq
MIRT2520886	hsa-miR-4495	CLIP-seq
MIRT2520887	hsa-miR-4499	CLIP-seq
MIRT952207	hsa-miR-4512	CLIP-seq
MIRT2520888	hsa-miR-4520a-3p	CLIP-seq
MIRT2520889	hsa-miR-4520a-5p	CLIP-seq
MIRT2520890	hsa-miR-4520b-5p	CLIP-seq
MIRT1981967	hsa-miR-4527	CLIP-seq
MIRT2520891	hsa-miR-4633-3p	CLIP-seq
MIRT1981968	hsa-miR-4638-3p	CLIP-seq
MIRT1981969	hsa-miR-4644	CLIP-seq
MIRT2520892	hsa-miR-4651	CLIP-seq
MIRT952213	hsa-miR-4652-3p	CLIP-seq
MIRT952216	hsa-miR-4656	CLIP-seq
MIRT2520893	hsa-miR-4660	CLIP-seq
MIRT2520894	hsa-miR-4664-5p	CLIP-seq
MIRT2520895	hsa-miR-4668-5p	CLIP-seq
MIRT2520896	hsa-miR-4675	CLIP-seq
MIRT952219	hsa-miR-4685-5p	CLIP-seq
MIRT2520897	hsa-miR-4691-3p	CLIP-seq
MIRT1981970	hsa-miR-4693-3p	CLIP-seq
MIRT952226	hsa-miR-4708-5p	CLIP-seq
MIRT2520898	hsa-miR-4710	CLIP-seq
MIRT2216863	hsa-miR-4715-3p	CLIP-seq
MIRT952229	hsa-miR-4725-3p	CLIP-seq
MIRT2520899	hsa-miR-4731-5p	CLIP-seq
MIRT2520900	hsa-miR-4741	CLIP-seq
MIRT952238	hsa-miR-4768-5p	CLIP-seq
MIRT1981973	hsa-miR-4790-3p	CLIP-seq
MIRT2520901	hsa-miR-4792	CLIP-seq
MIRT952239	hsa-miR-4794	CLIP-seq
MIRT2520902	hsa-miR-4797-5p	CLIP-seq
MIRT2520903	hsa-miR-491-5p	CLIP-seq
MIRT2520904	hsa-miR-494	CLIP-seq
MIRT2520905	hsa-miR-495	CLIP-seq
MIRT2520906	hsa-miR-500a	CLIP-seq
MIRT952246	hsa-miR-500b	CLIP-seq
MIRT2520907	hsa-miR-5047	CLIP-seq
MIRT952253	hsa-miR-526b	CLIP-seq
MIRT952255	hsa-miR-542-3p	CLIP-seq
MIRT2679751	hsa-miR-548ae	CLIP-seq
MIRT2679752	hsa-miR-548aj	CLIP-seq
MIRT2679753	hsa-miR-548am	CLIP-seq
MIRT1981977	hsa-miR-548q	CLIP-seq
MIRT2520908	hsa-miR-548u	CLIP-seq
MIRT2679754	hsa-miR-548x	CLIP-seq
MIRT952256	hsa-miR-558	CLIP-seq
MIRT2520909	hsa-miR-608	CLIP-seq
MIRT2520911	hsa-miR-617	CLIP-seq
MIRT2520912	hsa-miR-626	CLIP-seq
MIRT2520913	hsa-miR-632	CLIP-seq
MIRT1981979	hsa-miR-657	CLIP-seq
MIRT952263	hsa-miR-661	CLIP-seq
MIRT952264	hsa-miR-670	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000932	Component	P-body	IBA
GO:0000932	Component	P-body	IEA
GO:0003723	Function	RNA binding	IEA
GO:0003729	Function	MRNA binding	IBA
GO:0003729	Function	MRNA binding	IEA
GO:0005515	Function	Protein binding	IPI	15161933, 15778465, 16364915, 19966221, 20584987, 21516116, 24981860, 25036637, 25416956, 26184334, 26496610, 27107012, 28514442, 29892012, 31422817, 31439631, 31515488, 32296183, 33961781, 35271311, 36931259, 39251607
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0016020	Component	Membrane	HDA	19946888
GO:0031087	Process	Deadenylation-independent decapping of nuclear-transcribed mRNA	IBA
GO:0031087	Process	Deadenylation-independent decapping of nuclear-transcribed mRNA	IEA
GO:0033962	Process	P-body assembly	IBA
GO:0036464	Component	Cytoplasmic ribonucleoprotein granule	IDA
GO:0042802	Function	Identical protein binding	IPI	18678652, 25416956, 29892012, 31515488, 32296183

Other IDs

• MIM: 609842
• HGNC: 26114
• e!Ensembl: ENSG00000179151

Protein

• UniProt ID: Q96F86
• Protein name: Enhancer of mRNA-decapping protein 3 (LSM16 homolog) (YjeF N-terminal domain-containing protein 2) (YjeF_N2) (hYjeF_N2) (YjeF domain-containing protein 1)
• Protein function: Binds single-stranded RNA. Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping. May play a role in spermiogenesis and oogenesis. {ECO:0000269|PubMed:16364915, ECO:0000269|PubMed:17533573, ECO:0000269|PubM
• PDB: 2VC8, 2WAX, 2WAY, 3D3J, 3D3K, 6S8S
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12701	LSM14	4 → 67	Scd6-like Sm domain	Domain
  PF16598	Edc3_linker	102 → 197		Family
  PF09532	FDF	198 → 301	FDF domain	Domain
  PF03853	YjeF_N	301 → 467	YjeF-related protein N-terminus	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed in theca and granulosa cells in ovary, and in spermatids of the meiotic division part II and apical membrane of Sertoli cells in testis (at protein level). Also expressed in brain and mammary gland. {ECO:0000269|PubMed:175335
• Sequence:

  MATDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDIT
  ELKILEIPGPGDNQHFGDLHQTELGPSGAGCQVGINQNGTGKFVKKPASSSSAPQNIPKR
  TDVKSQDVAVSPQQQQCSKSYVDRHMESLSQSKSFRRRHNSWSSSSRHPNQATPKKSGLK
  NGQMKNKDDECFGDDIEEIPDTDFDFEGNLALFDKAAVFEEIDTYERRSGTRSRGIPNER
  PTRYRHDENILESEPIVYRRIIVPHNVSKEFCTDSGLVVPSISYELHKKLLSVAEKHGLT
  LERRLEMTGVCASQMALTLLGGPNRLNPKNVHQRPTVALLCGPHVKGAQGISCGRHLANH
  DVQVILFLPNFVKMLESITNELSLFSKTQGQQVSSLKDLPTSPVDLVINCLDCPENVFLR
  DQPWYKAAVAWANQNRAPVLSIDPPVHEVEQGIDAKWSLALGLPLPLGEHAGRIYLCDIG
  IPQQVFQEVGINYHSPFGCKFVIPLHSA

• Sequence length: 508

Pathways

KEGG:

RNA degradation

Reactome:

mRNA decay by 5' to 3' exoribonuclease

Associated diseases

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Intellectual disability, autosomal recessive 50	Pathogenic	rs2505375430, rs1057517676	RCV003993707 RCV000412560

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
EDC3-related disorder	Likely benign	rs562794805, rs764673612, rs764338631, rs138195822	RCV003911398 RCV003949384 RCV003944673 RCV003942905

Associations from Text Mining
Disease Name	Relationship Type	References
Conversion Disorder	Associate	25701870
Intellectual Disability	Associate	25701870, 29685133
Nervous System Malformations	Associate	25701870
Neuroblastoma	Associate	29685133
Polycystic Kidney Autosomal Dominant	Associate	38404150