CCDC170 (coiled-coil domain containing 170)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID 80129
Gene name Coiled-coil domain containing 170
Gene symbol CCDC170
Synonyms (NCBI Gene)
C6orf97bA282P11.1
Chromosome 6
Chromosome location 6q25.1
Summary The function of this gene and its encoded protein is not known. Several genome-wide association studies have implicated the region around this gene to be involved in breast cancer and bone mineral density, but no link to this specific gene has been found.
miRNA miRNA information provided by mirtarbase database.
2
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (2)
miRTarBase ID miRNA Experiments Reference
MIRT024045 hsa-miR-1-3p Microarray 18668037
MIRT030162 hsa-miR-26b-5p Microarray 19088304
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
10
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (10)
GO ID Ontology Definition Evidence Reference
GO:0000226 Process Microtubule cytoskeleton organization IBA
GO:0000226 Process Microtubule cytoskeleton organization IDA 28687497
GO:0005515 Function Protein binding IPI 25416956, 32296183
GO:0005794 Component Golgi apparatus IBA
GO:0005794 Component Golgi apparatus IDA 28687497
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8IYT3
Protein name Coiled-coil domain-containing protein 170
Protein function Plays a role in Golgi-associated microtubules organization and stabilization.
Family and domains
Sequence 
MSLDCTSHIALGAASPAPEETYDHLSEVPVTREQLNHYRNVAQNARSELAATLVKFECAQ
SELQDLRSKMLSKEVSCQELKAEMESYKENNARKSSLLTSLRDRVQELEEESAALSTSKI
RTEITAHAAIKENQELKKKVVELNEKLQKCSKENEENKKQVSKNCRKHEEFLTQLRDCLD
PDERNDKASDEDLILKLRDLRKENEFVKGQIVILEETINVHEMEAKASRETIMRLASEVN
REQKKAASCTEEKEKLNQDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQEVSLLKK
SSSELEKSLKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREE
SRDRMVSQLEAQISELVEQLGKESGFHQKALQRAQKAENMLETLQGQLTHLEAELVSGGV
LRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVIENK
TIAHNLQRKLKTQKERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQK
KVERLQKELNTCRDLHTELKAKLADTNELKIKTLEQTKAIEDLNKSRDQLEKMKEKAEKK
LMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKKSLEEAEKREKQLADFREVVSQM
LGLNVTSLALPDYEIIKCLERLVHSHQHHFVTCACLKDVTTGQERHPQGHLQLLH
Sequence length 715
Interactions View interactions
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (3)
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
CCDC170-related condition Conflicting classifications of pathogenicity rs6929137 RCV005359306
Estrogen resistance syndrome Uncertain significance; Conflicting classifications of pathogenicity; Benign rs12662670, rs6929137, rs3734805, rs9383589, rs12665607, rs2046210, rs9397435 RCV000143989
RCV000143990
RCV000143991
RCV000143992
RCV000143993
RCV000143994
RCV000143995
Familial cancer of breast Uncertain significance rs3734805 RCV005886954
Show/Hide Text Mining Associations (9)
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Breast Neoplasms Associate 20453838, 20661439, 21552322, 22879957, 23486537, 24127041, 24289300, 25116933, 25370037, 25862352, 27525837, 27848153, 28687497, 28761973, 31125336
View all (6 more)
Carcinogenesis Associate 25370037
Leukemia Myelogenous Chronic BCR ABL Positive Associate 37774059
Neoplasms Associate 25370037
Osteoporosis Associate 35414641, 35511874
Ovarian Neoplasms Associate 37024829
Sarcopenia Associate 32076017
ST Elevation Myocardial Infarction Associate 30382883
Triple Negative Breast Neoplasms Associate 21844186