WWC2 (WW and C2 domain containing 2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 80014 |
| Gene name | WW and C2 domain containing 2 |
| Gene symbol | WWC2 |
| Synonyms (NCBI Gene) |
BOMB
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| Chromosome | 4 |
| Chromosome location | 4q35.1 |
| Summary | This gene encodes a member of the WW-and-C2-domain-containing family of proteins. Members of this family have two N-terminal WW domains that mediate binding to target proteins harboring L/PPxY motifs, an internal C2 domain for membrane association, and C- |
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miRNA
miRNA information provided by mirtarbase database.
364
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
27
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q6AWC2 | |||||||||||||||
| Protein name | Protein WWC2 (BH-3-only member B) (WW domain-containing protein 2) | |||||||||||||||
| Protein function | Regulator of the Hippo signaling pathway, also known as the Salvador-Warts-Hippo (SWH) pathway. Enhances phosphorylation of LATS1 and YAP1 and negatively regulates cell proliferation and organ growth due to a suppression of the transcriptional a | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 1192 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
2
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