ATAT1 (alpha tubulin acetyltransferase 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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79969 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Alpha tubulin acetyltransferase 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ATAT1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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C6orf134, MEC17, Nbla00487, TAT, alpha-TAT, alpha-TAT1 |
Chromosome
Chromosome number
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6 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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6p21.33 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a protein that localizes to clathrin-coated pits, where it acetylates alpha tubulin on lysine 40. This process may be important in microtubule growth, for instance during chemotaxis and the formation of cilium. Alternative splicing resul |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q5SQI0 | ||||||||||
Protein name | Alpha-tubulin N-acetyltransferase 1 (Alpha-TAT) (Alpha-TAT1) (TAT) (EC 2.3.1.108) (Acetyltransferase mec-17 homolog) | ||||||||||
Protein function | Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin | ||||||||||
PDB | 3VWD , 3VWE , 4B5O , 4B5P , 4GS4 , 4IF5 , 4PK2 , 4PK3 , 4U9Y , 4U9Z | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 421 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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