Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
79924
Gene name Gene Name - the full gene name approved by the HGNC.
Adrenomedullin 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ADM2
Synonyms (NCBI Gene) Gene synonyms aliases
AM2, dJ579N16.4
Chromosome Chromosome number
22
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
22q13.33
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the calcitonin gene-related peptide (CGRP)/calcitonin family of hormones that play a role in the regulation of cardiovascular homeostasis, prolactin release, anti-diuresis, anti-natriuresis, and regulation of food and water i
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT662322 hsa-miR-1245a HITS-CLIP 23824327
MIRT662321 hsa-miR-8079 HITS-CLIP 23824327
MIRT662320 hsa-miR-6513-3p HITS-CLIP 23824327
MIRT662319 hsa-miR-6840-3p HITS-CLIP 23824327
MIRT662318 hsa-miR-1915-3p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001525 Process Angiogenesis IDA 20596610
GO:0005179 Function Hormone activity IEA
GO:0005576 Component Extracellular region TAS
GO:0006468 Process Protein phosphorylation IDA 20596610
GO:0007186 Process G protein-coupled receptor signaling pathway TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
608682 28898 ENSG00000128165
Protein
UniProt ID Q7Z4H4
Protein name Protein ADM2 (Intermedin) [Cleaved into: Adrenomedullin-2 (AM2) (Intermedin-long) (IMDL); Intermedin-short (IMDS)]
Protein function Intermedin/ADM2 is a peptide hormone that plays a role as physiological regulator of gastrointestinal and cardiovascular bioactivities mediated by the CALCRL-RAMPs receptor complexes (PubMed:14615490). Activates the cAMP-dependent pathway throug
PDB 6D1U , 6UVA
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00214 Calc_CGRP_IAPP 45 148 Calcitonin / CGRP / IAPP family Family
Tissue specificity TISSUE SPECIFICITY: Expressed in the esophagus, stomach, jejunum, ileum, ileocecum, ascending colon, transverse colon, descending colon and rectum. Expressed in myocardial cells of the heart, renal tubular cells, hypothalamus, and pituitary. {ECO:0000269|
Sequence
Sequence length 148
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Neuroactive ligand-receptor interaction
Vascular smooth muscle contraction
  G alpha (s) signalling events
Calcitonin-like ligand receptors
ADORA2B mediated anti-inflammatory cytokines production