PEAK1 (pseudopodium enriched atypical kinase 1)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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79834 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Pseudopodium enriched atypical kinase 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PEAK1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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SGK269 |
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Chromosome
Chromosome number
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15 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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15q24.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a non-receptor tyrosine kinase that is a member of the new kinase family three (NFK3) family. In migrating cells, the encoded protein is associated with the actin cytoskeleton and focal adhesions and promotes developing focal adhesion el |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q9H792 | ||||||||||
| Protein name | Inactive tyrosine-protein kinase PEAK1 (Pseudopodium-enriched atypical kinase 1) (Sugen kinase 269) (Tyrosine-protein kinase SgK269) | ||||||||||
| Protein function | Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics (PubMed:20534451, PubMed:23105102, PubMed:35687021). Acts as a scaffold for | ||||||||||
| PDB | 6BHC , 8DGM | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 1746 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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