PEAK1 (pseudopodium enriched atypical kinase 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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79834 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Pseudopodium enriched atypical kinase 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PEAK1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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SGK269 |
Chromosome
Chromosome number
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15 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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15q24.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a non-receptor tyrosine kinase that is a member of the new kinase family three (NFK3) family. In migrating cells, the encoded protein is associated with the actin cytoskeleton and focal adhesions and promotes developing focal adhesion el |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q9H792 | ||||||||||
Protein name | Inactive tyrosine-protein kinase PEAK1 (Pseudopodium-enriched atypical kinase 1) (Sugen kinase 269) (Tyrosine-protein kinase SgK269) | ||||||||||
Protein function | Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics (PubMed:20534451, PubMed:23105102, PubMed:35687021). Acts as a scaffold for | ||||||||||
PDB | 6BHC , 8DGM | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 1746 | ||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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