METTL8 (methyltransferase 8, tRNA N3-cytidine)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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79828 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Methyltransferase 8, tRNA N3-cytidine |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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METTL8 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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TIP |
Chromosome
Chromosome number
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2 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2q31.1 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q9H825 | ||||||||||
Protein name | tRNA N(3)-cytidine methyltransferase METTL8, mitochondrial (EC 2.1.1.-) (Methyltransferase-like protein 8) (mRNA N(3)-methylcytidine methyltransferase METTL8) (EC 2.1.1.-) | ||||||||||
Protein function | Mitochondrial S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of mitochondrial tRNA(Ser)(UCN) and tRNA(Thr) (PubMed:34774131, PubMed:35017528). N(3)-meth | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 291 | ||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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