Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
79811
Gene name Gene Name - the full gene name approved by the HGNC.
SAFB like transcription modulator
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SLTM
Synonyms (NCBI Gene) Gene synonyms aliases
Met
Chromosome Chromosome number
15
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
15q22.1
SNPs SNP information provided by dbSNP.
SNP ID Visualize variation Clinical significance Consequence
rs1401798992 G>C,T Likely-pathogenic Downstream transcript variant, non coding transcript variant, coding sequence variant, missense variant, genic downstream transcript variant
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT021156 hsa-miR-186-5p Sequencing 20371350
MIRT1370164 hsa-miR-101 CLIP-seq
MIRT1370165 hsa-miR-105 CLIP-seq
MIRT1370166 hsa-miR-1237 CLIP-seq
MIRT1370167 hsa-miR-1250 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003676 Function Nucleic acid binding IEA
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0003723 Function RNA binding IEA
GO:0005515 Function Protein binding IPI 32296183
GO:0005634 Component Nucleus IBA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
620992 20709 ENSG00000137776
Protein
UniProt ID Q9NWH9
Protein name SAFB-like transcription modulator (Modulator of estrogen-induced transcription)
Protein function When overexpressed, acts as a general inhibitor of transcription that eventually leads to apoptosis.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02037 SAP 22 56 SAP domain Family
PF00076 RRM_1 386 456 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
Sequence
MAAATGAVAASAASGQAEGKKITDLRVIDLKSELKRRNLDITGVKTVLISRLKQAIEEEG
GDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGN
DELKDSEEFGENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGED
DTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAED
DNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMN
ANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKD
SKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNAR
SPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQLIS
VEKVKGDPSKKEMKKENDEKSSSR
SSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESI
KKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYR
RKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERL
QRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQ
EKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHRERGRFP
ESSAVQSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRE
SDRREVRGERDERRTVIIHDRPDITHPRHPREAGPNPSRPTSWKSEGSMSTDKRETRVER
PERSGREVSGHSVRGAPPGNRSSASGYGSREGDRGVITDRGGGSQHYPEERHVVERHGRD
TSGPRKEWHGPPSQGPSYHDTRRMGDGRAGAGMITQHSSNASPINRIVQISGNSMPRGSG
SGFKPFKGGPPRRF
Sequence length 1034
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Disease merge term Disease name dbSNP ID References
Jeune Thoracic Dystrophy jeune thoracic dystrophy rs1401798992 N/A
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Schizophrenia Schizophrenia N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Abnormalities Drug Induced Associate 25087088
Adenocarcinoma Associate 15720819, 17062664, 18349821, 18379349, 19096300, 22042947, 22052229, 22198430, 22450065, 23449277, 25886066, 26183759, 26315110, 27080983, 27300295
View all (17 more)
Adenocarcinoma Clear Cell Associate 21478826, 21983935
Adenocarcinoma Mucinous Associate 32840168
Adenocarcinoma Of Esophagus Associate 16327494
Adenocarcinoma of Lung Associate 18093943, 19096300, 20150826, 22975805, 25079552, 25886066, 25922291, 25971939, 26066407, 26098749, 26416301, 26791794, 26845116, 27060149, 27151654
View all (39 more)
Adenocarcinoma of Lung Stimulate 19817696
Adenoma Associate 34801057
Adenoma Pleomorphic Associate 33838468
Adenomatous Polyposis Coli Associate 28141798