LRRC31 (leucine rich repeat containing 31)

Gene

• Entrez ID: 79782
• Gene name: Leucine rich repeat containing 31
• Gene symbol: LRRC31
• Synonyms (NCBI Gene): HEL-S-293
• Chromosome: 3
• Chromosome location: 3q26.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT707462	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT551418	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT551417	hsa-miR-656-3p	HITS-CLIP	21572407
MIRT551416	hsa-miR-511-3p	HITS-CLIP	21572407
MIRT551415	hsa-miR-6504-3p	HITS-CLIP	21572407
MIRT551414	hsa-miR-223-5p	HITS-CLIP	21572407
MIRT551413	hsa-miR-3924	HITS-CLIP	21572407
MIRT551418	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT551417	hsa-miR-656-3p	PAR-CLIP	21572407
MIRT551416	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT551415	hsa-miR-6504-3p	PAR-CLIP	21572407
MIRT551414	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT551413	hsa-miR-3924	PAR-CLIP	21572407
MIRT707462	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT551418	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT551417	hsa-miR-656-3p	HITS-CLIP	21572407
MIRT551416	hsa-miR-511-3p	HITS-CLIP	21572407
MIRT551415	hsa-miR-6504-3p	HITS-CLIP	21572407
MIRT551414	hsa-miR-223-5p	HITS-CLIP	21572407
MIRT551413	hsa-miR-3924	HITS-CLIP	21572407
MIRT551418	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT551417	hsa-miR-656-3p	PAR-CLIP	21572407
MIRT551416	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT551415	hsa-miR-6504-3p	PAR-CLIP	21572407
MIRT551414	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT551413	hsa-miR-3924	PAR-CLIP	21572407
MIRT1119464	hsa-miR-124	CLIP-seq
MIRT1119465	hsa-miR-203	CLIP-seq
MIRT1119466	hsa-miR-3136-3p	CLIP-seq
MIRT1119467	hsa-miR-3163	CLIP-seq
MIRT1119468	hsa-miR-4694-3p	CLIP-seq
MIRT1119469	hsa-miR-506	CLIP-seq
MIRT1119470	hsa-miR-522	CLIP-seq
MIRT1119471	hsa-miR-548an	CLIP-seq
MIRT1119472	hsa-miR-577	CLIP-seq
MIRT2264194	hsa-miR-329	CLIP-seq
MIRT2264195	hsa-miR-362-3p	CLIP-seq
MIRT2264196	hsa-miR-3941	CLIP-seq
MIRT2264197	hsa-miR-466	CLIP-seq
MIRT2264198	hsa-miR-4672	CLIP-seq
MIRT2264199	hsa-miR-4789-3p	CLIP-seq
MIRT2264200	hsa-miR-603	CLIP-seq

Other IDs

• MIM: 620925
• HGNC: 26261
• e!Ensembl: ENSG00000114248

Protein

• UniProt ID: Q6UY01
• Protein name: Leucine-rich repeat-containing protein 31
• Sequence:

  MSQTRKKTSSEGETKPQTSTVNKFLRGSNAESRKEDNDLKTSDSQPSDWIQKTATSETAK
  PLSSEMEWRSSMEKNEHFLQKLGKKAVNKCLDLNNCGLTTADMKEMVALLPFLPDLEELD
  ISWNGFVGGTLLSITQQMHLVSKLKILRLGSCRLTTDDVQALGEAFEMIPELEELNLSWN
  SKVGGNLPLILQKFQKGSKIQMIELVDCSLTSEDGTFLGQLLPMLQSLEVLDLSINRDIV
  GSLNSIAQGLKSTSNLKVLKLHSCGLSQKSVKILDAAFRYLGELRKLDLSCNKDLGGGFE
  DSPAQLVMLKHLQVLDLHQCSLTADDVMSLTQVIPLLSNLQELDLSANKKMGSSSENLLS
  RLRFLPALKSLVINNCALESETFTALAEASVHLSALEVFNLSWNKCVGGNLKLLLETLKL
  SMSLQVLRLSSCSLVTEDVALLASVIQTGHLAKLQKLDLSYNDSICDAGWTMFCQNVRFL
  KELIELDISLRPSNFRDCGQWFRHLLYAVTKLPQITEIGMKRWILPASQEEELECFDQDK
  KRSIHFDHGGFQ

• Sequence length: 552

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Glioma	Glioma	rs121909219, rs121909224, rs587776667, rs587776671, rs121909239, rs121909241, rs28933368, rs121913500, rs55863639, rs786201995, rs786202517, rs786201044, rs398123317, rs1057518425, rs121913499, rs1060500122, rs781647403, rs1060500126, rs1554897889, rs1114167629, rs1114167656, rs587782603, rs1554893824, rs1554900615, rs1564568660, rs786204900, rs762518389, rs1339631701	24908248
Multiple myeloma	Multiple Myeloma	rs11540652, rs78311289, rs121913482, rs397507340, rs121913343, rs121913240, rs121913529, rs730882018, rs1057517992, rs121913527, rs756183569, rs746646631, rs1574706907, rs372078034, rs745380962, rs751524927, rs1575079076, rs1575446356, rs1478603808, rs1578264146, rs1578673280, rs1579484570, rs1579491104, rs1171390403, rs1582867955, rs764264135, rs951047896, rs890521687, rs1581495906, rs1587941402, rs1003155450, rs1588299621, rs1591100766, rs1591693095, rs1029296641, rs1593107841, rs1208575764, rs1593835248, rs1594406727, rs1594966387, rs1595889508, rs1159294530, rs1597073318, rs1135402871, rs1599413207, rs1418268495, rs1212577459, rs1600394490, rs1455074519, rs1603113792, rs1603415028, rs1602247047, rs1603452612	23955597

Unknown
Disease term	Disease name	Evidence	References	Source
Uterine Fibroids	Uterine Fibroids			GWAS

Associations from Text Mining
Disease Name	Relationship Type	References
Arthritis Rheumatoid	Associate	28413214
Carcinoma Squamous Cell	Associate	37487414
Coronary Disease	Associate	24349443
Diabetes Mellitus Type 2	Associate	24349443, 26720590, 32296102
Eosinophilia	Associate	26462420
Eosinophilic Esophagitis	Stimulate	26462420
Glioma	Associate	24908248
HIV Infections	Associate	33407441
Hypoalphalipoproteinemias	Associate	26720590
Mental Disorders	Associate	33407441