FZD3 (frizzled class receptor 3)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 7976 |
| Gene name | Frizzled class receptor 3 |
| Gene symbol | FZD3 |
| Synonyms (NCBI Gene) |
Fz-3
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| Chromosome | 8 |
| Chromosome location | 8p21.1 |
| Summary | This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the be |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
950
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
64
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9NPG1 | |||||||||||||||
| Protein name | Frizzled-3 (Fz-3) (hFz3) | |||||||||||||||
| Protein function | Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activat | |||||||||||||||
| PDB | 8JHC , 8JHI , 8Q7O , 8QW4 | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed. Relatively high expression in the CNS, including regions of the limbic system, in kidney, pancreas, skeletal muscle, uterus and testis. | |||||||||||||||
| Sequence |
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| Sequence length | 666 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
6
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