FZD3 (frizzled class receptor 3)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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7976 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Frizzled class receptor 3 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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FZD3 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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Fz-3 |
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Chromosome
Chromosome number
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8 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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8p21.1 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the be |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | Q9NPG1 | |||||||||||||||
| Protein name | Frizzled-3 (Fz-3) (hFz3) | |||||||||||||||
| Protein function | Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activat | |||||||||||||||
| PDB | 8JHC , 8JHI , 8Q7O , 8QW4 | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed. Relatively high expression in the CNS, including regions of the limbic system, in kidney, pancreas, skeletal muscle, uterus and testis. | |||||||||||||||
| Sequence |
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| Sequence length | 666 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||