ZNF668 (zinc finger protein 668)

Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
79759
Gene name Gene Name - the full gene name approved by the HGNC.
Zinc finger protein 668
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ZNF668
Synonyms (NCBI Gene) Gene synonyms aliases
NEDGEF
Disease Acronyms (UniProt) Disease acronyms from UniProt database
NEDGEF
Chromosome Chromosome number
16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
16p11.2
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(3)
miRTarBase ID miRNA Experiments Reference
MIRT047905 hsa-miR-30c-5p CLASH 23622248
MIRT1534505 hsa-miR-4305 CLIP-seq
MIRT1534506 hsa-miR-4704-3p CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(8)
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IEA
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA 21873635
GO:0001227 Function DNA-binding transcription repressor activity, RNA polymerase II-specific IEA
GO:0001228 Function DNA-binding transcription activator activity, RNA polymerase II-specific IBA 21873635
GO:0005634 Component Nucleus IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
617103 25821 ENSG00000167394
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q96K58
Protein name Zinc finger protein 668
Protein function May be involved in transcriptional regulation. May play a role in DNA repair process.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00096 zf-C2H2 84 → 106 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 112 → 134 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 140 → 162 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 168 → 190 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 224 → 246 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 252 → 274 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 280 → 302 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 308 → 330 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 336 → 358 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 364 → 386 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 392 → 414 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 516 → 538 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 544 → 566 Zinc finger, C2H2 type Domain
PF13894 zf-C2H2_4 572 → 595 Domain
Sequence 
MEVEAAEARSPAPGYKRSGRRYKCVSCTKTFPNAPRAARHAATHGPADCSEEVAEVKPKP
ETEAKAEEASGEKVSGSAAKPRPYACPLCPKAYKTAPELRSHGRSHTGEKPFPCPECGRR
FMQPVCLRVHLASHAGELPFRCAHCPKAYGALSKLKIHQRGHTGERPYACADCGKSFADP
SVFRKHRRTHAGLRPYSCERCGKAYAELKDLRNHERSHTGERPFLCSECGKSFSRSSSLT
CHQRIHAAQKPYRCPACGKGFTQLSSYQSHERTHSGEKPFLCPRCGRMFSDPSSFRRHQR
AHEGVKPYHCEKCGKDFRQPADLAMHRRVHTGDRPFKCLQCDKTFVASWDLKRHALVHSG
QRPFRCEECGRAFAERASLTKHSRVHSGERPFHCNACGKSFVVSSSLRKHERTHRSSEAA
GVPPAQELVVGLALPVGVAGESSAAPAAGAGLGDPPAGLLGLPPESGGVMATQWQVVGMT
VEHVECQDAGVREAPGPLEGAGEAGGEEADEKPPQFVCRECKETFSTMTLLRRHERSHPE
LRPFPCTQCGKSFSDRAGLRKHSRTHSSVRPYTCPHCPKAFLSASDLRKHERTHPVPMGT
PTPLEPLVALLGMPEEGPA
Sequence length 619
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
  Reactome
    Generic Transcription Pathway
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Causal Diseases (2)
Causal
Disease term Disease name dbSNP ID References
Breast cancer Malignant neoplasm of breast rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158
View all (309 more)
Ependymoma Ependymoma, Cellular Ependymoma rs1555165565, rs1555993293 26075792
Show/Hide Unknown Diseases (1)
Unknown
Disease term Disease name Evidence References Source
Anaplastic ependymoma Anaplastic Ependymoma 26075792 ClinVar
Show/Hide Text Mining Associations (8)
Associations from Text Mining
Disease Name Relationship Type References
Breast Neoplasms Inhibit 21852383, 37240013
Breast Neoplasms Associate 23777805
HAIR AN syndrome Associate 23777805
Melanoma Associate 21343389
Neoplasms Inhibit 21852383, 23777805, 37240013
Neoplasms Associate 32859265
Syndrome Associate 26633546
Urinary Bladder Neoplasms Associate 37240013