AAGAB (alpha and gamma adaptin binding protein)

Gene

• Entrez ID: 79719
• Gene name: Alpha and gamma adaptin binding protein
• Gene symbol: AAGAB
• Synonyms (NCBI Gene): KPPP1, PPKP1, PPKP1A, p34
• Chromosome: 15
• Chromosome location: 15q23
• Summary: The protein encoded by this gene interacts with the gamma-adaptin and alpha-adaptin subunits of complexes involved in clathrin-coated vesicle trafficking. Mutations in this gene are associated with type I punctate palmoplantar keratoderma. Alternatively s

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs200564757	G>A,T	Pathogenic	Coding sequence variant, synonymous variant, stop gained
rs746488412	G>A	Pathogenic	Stop gained, coding sequence variant
rs753247583	C>T	Pathogenic	Splice donor variant, genic downstream transcript variant
rs781596375	C>-	Pathogenic	Frameshift variant, coding sequence variant
rs1057518846	C>A,G	Likely-pathogenic	Splice donor variant
rs1567027297	CT>-	Pathogenic	Coding sequence variant, frameshift variant
rs1567027610	GAAA>-	Pathogenic	Coding sequence variant, frameshift variant, 5 prime UTR variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT049395	hsa-miR-92a-3p	CLASH	23622248
MIRT038743	hsa-miR-93-3p	CLASH	23622248
MIRT624893	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT624892	hsa-miR-548at-3p	HITS-CLIP	23824327
MIRT624891	hsa-miR-548ay-3p	HITS-CLIP	23824327
MIRT624890	hsa-miR-651-3p	HITS-CLIP	23824327
MIRT624889	hsa-miR-4799-5p	HITS-CLIP	23824327
MIRT624888	hsa-miR-4477b	HITS-CLIP	23824327
MIRT624887	hsa-miR-4263	HITS-CLIP	23824327
MIRT624886	hsa-miR-576-5p	HITS-CLIP	23824327
MIRT624885	hsa-miR-7856-5p	HITS-CLIP	23824327
MIRT669718	hsa-miR-548ac	HITS-CLIP	23824327
MIRT669717	hsa-miR-548bb-3p	HITS-CLIP	23824327
MIRT669716	hsa-miR-548d-3p	HITS-CLIP	23824327
MIRT669715	hsa-miR-548h-3p	HITS-CLIP	23824327
MIRT669714	hsa-miR-548z	HITS-CLIP	23824327
MIRT669713	hsa-miR-548aa	HITS-CLIP	23824327
MIRT669712	hsa-miR-548ap-3p	HITS-CLIP	23824327
MIRT669711	hsa-miR-548t-3p	HITS-CLIP	23824327
MIRT669710	hsa-miR-3184-3p	HITS-CLIP	23824327
MIRT669709	hsa-miR-3691-3p	HITS-CLIP	23824327
MIRT624893	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT624892	hsa-miR-548at-3p	HITS-CLIP	23824327
MIRT624891	hsa-miR-548ay-3p	HITS-CLIP	23824327
MIRT624890	hsa-miR-651-3p	HITS-CLIP	23824327
MIRT624889	hsa-miR-4799-5p	HITS-CLIP	23824327
MIRT624888	hsa-miR-4477b	HITS-CLIP	23824327
MIRT624887	hsa-miR-4263	HITS-CLIP	23824327
MIRT624886	hsa-miR-576-5p	HITS-CLIP	23824327
MIRT624885	hsa-miR-7856-5p	HITS-CLIP	23824327
MIRT624899	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT624898	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT624897	hsa-miR-507	HITS-CLIP	23824327
MIRT624896	hsa-miR-557	HITS-CLIP	23824327
MIRT624895	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT624894	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT624893	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT624892	hsa-miR-548at-3p	HITS-CLIP	23824327
MIRT624891	hsa-miR-548ay-3p	HITS-CLIP	23824327
MIRT624890	hsa-miR-651-3p	HITS-CLIP	23824327
MIRT624889	hsa-miR-4799-5p	HITS-CLIP	23824327
MIRT624888	hsa-miR-4477b	HITS-CLIP	23824327
MIRT624887	hsa-miR-4263	HITS-CLIP	23824327
MIRT624886	hsa-miR-576-5p	HITS-CLIP	23824327
MIRT624885	hsa-miR-7856-5p	HITS-CLIP	23824327
MIRT624893	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT624892	hsa-miR-548at-3p	HITS-CLIP	23824327
MIRT624891	hsa-miR-548ay-3p	HITS-CLIP	23824327
MIRT624890	hsa-miR-651-3p	HITS-CLIP	23824327
MIRT624889	hsa-miR-4799-5p	HITS-CLIP	23824327
MIRT624888	hsa-miR-4477b	HITS-CLIP	23824327
MIRT624887	hsa-miR-4263	HITS-CLIP	23824327
MIRT624886	hsa-miR-576-5p	HITS-CLIP	23824327
MIRT624885	hsa-miR-7856-5p	HITS-CLIP	23824327
MIRT669718	hsa-miR-548ac	HITS-CLIP	23824327
MIRT669717	hsa-miR-548bb-3p	HITS-CLIP	23824327
MIRT669716	hsa-miR-548d-3p	HITS-CLIP	23824327
MIRT669715	hsa-miR-548h-3p	HITS-CLIP	23824327
MIRT669714	hsa-miR-548z	HITS-CLIP	23824327
MIRT669713	hsa-miR-548aa	HITS-CLIP	23824327
MIRT669712	hsa-miR-548ap-3p	HITS-CLIP	23824327
MIRT669711	hsa-miR-548t-3p	HITS-CLIP	23824327
MIRT669710	hsa-miR-3184-3p	HITS-CLIP	23824327
MIRT669709	hsa-miR-3691-3p	HITS-CLIP	23824327
MIRT624893	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT624892	hsa-miR-548at-3p	HITS-CLIP	23824327
MIRT624891	hsa-miR-548ay-3p	HITS-CLIP	23824327
MIRT624890	hsa-miR-651-3p	HITS-CLIP	23824327
MIRT624889	hsa-miR-4799-5p	HITS-CLIP	23824327
MIRT624888	hsa-miR-4477b	HITS-CLIP	23824327
MIRT624887	hsa-miR-4263	HITS-CLIP	23824327
MIRT624886	hsa-miR-576-5p	HITS-CLIP	23824327
MIRT624885	hsa-miR-7856-5p	HITS-CLIP	23824327
MIRT624899	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT624898	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT624897	hsa-miR-507	HITS-CLIP	23824327
MIRT624896	hsa-miR-557	HITS-CLIP	23824327
MIRT624895	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT624894	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT624893	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT624892	hsa-miR-548at-3p	HITS-CLIP	23824327
MIRT624891	hsa-miR-548ay-3p	HITS-CLIP	23824327
MIRT624890	hsa-miR-651-3p	HITS-CLIP	23824327
MIRT624889	hsa-miR-4799-5p	HITS-CLIP	23824327
MIRT624888	hsa-miR-4477b	HITS-CLIP	23824327
MIRT624887	hsa-miR-4263	HITS-CLIP	23824327
MIRT624886	hsa-miR-576-5p	HITS-CLIP	23824327
MIRT624885	hsa-miR-7856-5p	HITS-CLIP	23824327
MIRT756818	hsa-miR-1260	CLIP-seq
MIRT756819	hsa-miR-1260b	CLIP-seq
MIRT756820	hsa-miR-1271	CLIP-seq
MIRT756821	hsa-miR-1290	CLIP-seq
MIRT756822	hsa-miR-136	CLIP-seq
MIRT756823	hsa-miR-1587	CLIP-seq
MIRT756824	hsa-miR-182	CLIP-seq
MIRT756825	hsa-miR-1825	CLIP-seq
MIRT756826	hsa-miR-188-3p	CLIP-seq
MIRT756827	hsa-miR-18a	CLIP-seq
MIRT756828	hsa-miR-18b	CLIP-seq
MIRT756829	hsa-miR-198	CLIP-seq
MIRT756830	hsa-miR-199a-5p	CLIP-seq
MIRT756831	hsa-miR-199b-5p	CLIP-seq
MIRT756832	hsa-miR-202	CLIP-seq
MIRT756833	hsa-miR-2355-5p	CLIP-seq
MIRT756834	hsa-miR-28-5p	CLIP-seq
MIRT756835	hsa-miR-300	CLIP-seq
MIRT756836	hsa-miR-3121-5p	CLIP-seq
MIRT756837	hsa-miR-3136-3p	CLIP-seq
MIRT756838	hsa-miR-3139	CLIP-seq
MIRT756839	hsa-miR-3143	CLIP-seq
MIRT756840	hsa-miR-3144-5p	CLIP-seq
MIRT756841	hsa-miR-3150a-5p	CLIP-seq
MIRT756842	hsa-miR-3150b-5p	CLIP-seq
MIRT756843	hsa-miR-3152-5p	CLIP-seq
MIRT756844	hsa-miR-3156-3p	CLIP-seq
MIRT756845	hsa-miR-3161	CLIP-seq
MIRT756846	hsa-miR-3664-3p	CLIP-seq
MIRT756847	hsa-miR-3672	CLIP-seq
MIRT756848	hsa-miR-378g	CLIP-seq
MIRT756849	hsa-miR-381	CLIP-seq
MIRT756850	hsa-miR-3907	CLIP-seq
MIRT756851	hsa-miR-3919	CLIP-seq
MIRT756852	hsa-miR-3936	CLIP-seq
MIRT756853	hsa-miR-3974	CLIP-seq
MIRT756854	hsa-miR-3978	CLIP-seq
MIRT756855	hsa-miR-4255	CLIP-seq
MIRT756856	hsa-miR-4269	CLIP-seq
MIRT756857	hsa-miR-4279	CLIP-seq
MIRT756858	hsa-miR-4282	CLIP-seq
MIRT756859	hsa-miR-4286	CLIP-seq
MIRT756860	hsa-miR-4292	CLIP-seq
MIRT756861	hsa-miR-4301	CLIP-seq
MIRT756862	hsa-miR-4308	CLIP-seq
MIRT756863	hsa-miR-4329	CLIP-seq
MIRT756864	hsa-miR-4330	CLIP-seq
MIRT756865	hsa-miR-4470	CLIP-seq
MIRT756866	hsa-miR-4492	CLIP-seq
MIRT756867	hsa-miR-4498	CLIP-seq
MIRT756868	hsa-miR-4514	CLIP-seq
MIRT756869	hsa-miR-4517	CLIP-seq
MIRT756870	hsa-miR-4633-3p	CLIP-seq
MIRT756871	hsa-miR-4656	CLIP-seq
MIRT756872	hsa-miR-4659a-3p	CLIP-seq
MIRT756873	hsa-miR-4659b-3p	CLIP-seq
MIRT756874	hsa-miR-4665-3p	CLIP-seq
MIRT756875	hsa-miR-4675	CLIP-seq
MIRT756876	hsa-miR-4692	CLIP-seq
MIRT756877	hsa-miR-4735-3p	CLIP-seq
MIRT756878	hsa-miR-4741	CLIP-seq
MIRT756879	hsa-miR-4742-5p	CLIP-seq
MIRT756880	hsa-miR-4756-3p	CLIP-seq
MIRT756881	hsa-miR-4758-3p	CLIP-seq
MIRT756882	hsa-miR-4760-3p	CLIP-seq
MIRT756883	hsa-miR-4761-5p	CLIP-seq
MIRT756884	hsa-miR-4774-3p	CLIP-seq
MIRT756885	hsa-miR-500a	CLIP-seq
MIRT756886	hsa-miR-501-5p	CLIP-seq
MIRT756887	hsa-miR-543	CLIP-seq
MIRT756888	hsa-miR-548ae	CLIP-seq
MIRT756889	hsa-miR-548aj	CLIP-seq
MIRT756890	hsa-miR-548am	CLIP-seq
MIRT756891	hsa-miR-548x	CLIP-seq
MIRT756892	hsa-miR-621	CLIP-seq
MIRT756893	hsa-miR-624	CLIP-seq
MIRT756894	hsa-miR-670	CLIP-seq
MIRT756895	hsa-miR-7	CLIP-seq
MIRT756896	hsa-miR-708	CLIP-seq
MIRT756897	hsa-miR-762	CLIP-seq
MIRT756898	hsa-miR-873	CLIP-seq
MIRT756899	hsa-miR-875-3p	CLIP-seq
MIRT756900	hsa-miR-936	CLIP-seq
MIRT756901	hsa-miR-96	CLIP-seq
MIRT1555887	hsa-miR-1184	CLIP-seq
MIRT1555888	hsa-miR-1205	CLIP-seq
MIRT1555889	hsa-miR-1301	CLIP-seq
MIRT1555890	hsa-miR-22	CLIP-seq
MIRT1555891	hsa-miR-3158-5p	CLIP-seq
MIRT1555892	hsa-miR-4660	CLIP-seq
MIRT1555893	hsa-miR-5047	CLIP-seq
MIRT1555894	hsa-miR-544	CLIP-seq
MIRT1923177	hsa-miR-1208	CLIP-seq
MIRT756823	hsa-miR-1587	CLIP-seq
MIRT1923178	hsa-miR-196a	CLIP-seq
MIRT1923179	hsa-miR-196b	CLIP-seq
MIRT1923180	hsa-miR-1976	CLIP-seq
MIRT756832	hsa-miR-202	CLIP-seq
MIRT1555890	hsa-miR-22	CLIP-seq
MIRT1923181	hsa-miR-3119	CLIP-seq
MIRT756841	hsa-miR-3150a-5p	CLIP-seq
MIRT756842	hsa-miR-3150b-5p	CLIP-seq
MIRT1923182	hsa-miR-3160-3p	CLIP-seq
MIRT756845	hsa-miR-3161	CLIP-seq
MIRT1923183	hsa-miR-331-5p	CLIP-seq
MIRT1923184	hsa-miR-339-5p	CLIP-seq
MIRT1923185	hsa-miR-34c-3p	CLIP-seq
MIRT1923186	hsa-miR-3653	CLIP-seq
MIRT1923187	hsa-miR-3658	CLIP-seq
MIRT756847	hsa-miR-3672	CLIP-seq
MIRT1923188	hsa-miR-370	CLIP-seq
MIRT756851	hsa-miR-3919	CLIP-seq
MIRT1923189	hsa-miR-3925-3p	CLIP-seq
MIRT1923190	hsa-miR-3927	CLIP-seq
MIRT756856	hsa-miR-4269	CLIP-seq
MIRT756857	hsa-miR-4279	CLIP-seq
MIRT756863	hsa-miR-4329	CLIP-seq
MIRT756864	hsa-miR-4330	CLIP-seq
MIRT1923191	hsa-miR-4420	CLIP-seq
MIRT1923192	hsa-miR-4451	CLIP-seq
MIRT1923193	hsa-miR-4487	CLIP-seq
MIRT756866	hsa-miR-4492	CLIP-seq
MIRT756867	hsa-miR-4498	CLIP-seq
MIRT756868	hsa-miR-4514	CLIP-seq
MIRT1923194	hsa-miR-4540	CLIP-seq
MIRT756871	hsa-miR-4656	CLIP-seq
MIRT1923195	hsa-miR-4662a-3p	CLIP-seq
MIRT756875	hsa-miR-4675	CLIP-seq
MIRT756876	hsa-miR-4692	CLIP-seq
MIRT1923196	hsa-miR-4694-3p	CLIP-seq
MIRT1923197	hsa-miR-4704-3p	CLIP-seq
MIRT1923198	hsa-miR-4734	CLIP-seq
MIRT756878	hsa-miR-4741	CLIP-seq
MIRT1923199	hsa-miR-4742-3p	CLIP-seq
MIRT756879	hsa-miR-4742-5p	CLIP-seq
MIRT756880	hsa-miR-4756-3p	CLIP-seq
MIRT1923200	hsa-miR-4767	CLIP-seq
MIRT1923201	hsa-miR-483-3p	CLIP-seq
MIRT1923202	hsa-miR-522	CLIP-seq
MIRT756888	hsa-miR-548ae	CLIP-seq
MIRT756889	hsa-miR-548aj	CLIP-seq
MIRT756890	hsa-miR-548am	CLIP-seq
MIRT756891	hsa-miR-548x	CLIP-seq
MIRT1923203	hsa-miR-558	CLIP-seq
MIRT756892	hsa-miR-621	CLIP-seq
MIRT1923204	hsa-miR-630	CLIP-seq
MIRT1923205	hsa-miR-668	CLIP-seq
MIRT756897	hsa-miR-762	CLIP-seq
MIRT2164683	hsa-miR-1179	CLIP-seq
MIRT2164684	hsa-miR-1254	CLIP-seq
MIRT756820	hsa-miR-1271	CLIP-seq
MIRT2164685	hsa-miR-128	CLIP-seq
MIRT756823	hsa-miR-1587	CLIP-seq
MIRT756824	hsa-miR-182	CLIP-seq
MIRT2164686	hsa-miR-190	CLIP-seq
MIRT2164687	hsa-miR-190b	CLIP-seq
MIRT2164688	hsa-miR-27a	CLIP-seq
MIRT2164689	hsa-miR-27b	CLIP-seq
MIRT2164690	hsa-miR-3116	CLIP-seq
MIRT2164691	hsa-miR-3137	CLIP-seq
MIRT756845	hsa-miR-3161	CLIP-seq
MIRT2164692	hsa-miR-3616-3p	CLIP-seq
MIRT2164693	hsa-miR-3689d	CLIP-seq
MIRT2164694	hsa-miR-3692	CLIP-seq
MIRT756848	hsa-miR-378g	CLIP-seq
MIRT2164695	hsa-miR-4254	CLIP-seq
MIRT2164696	hsa-miR-4268	CLIP-seq
MIRT756856	hsa-miR-4269	CLIP-seq
MIRT2164697	hsa-miR-4436b-5p	CLIP-seq
MIRT2164698	hsa-miR-4448	CLIP-seq
MIRT756865	hsa-miR-4470	CLIP-seq
MIRT756866	hsa-miR-4492	CLIP-seq
MIRT756867	hsa-miR-4498	CLIP-seq
MIRT756868	hsa-miR-4514	CLIP-seq
MIRT756869	hsa-miR-4517	CLIP-seq
MIRT756871	hsa-miR-4656	CLIP-seq
MIRT756875	hsa-miR-4675	CLIP-seq
MIRT756876	hsa-miR-4692	CLIP-seq
MIRT2164699	hsa-miR-4721	CLIP-seq
MIRT756878	hsa-miR-4741	CLIP-seq
MIRT756879	hsa-miR-4742-5p	CLIP-seq
MIRT1555894	hsa-miR-544	CLIP-seq
MIRT756897	hsa-miR-762	CLIP-seq
MIRT2164700	hsa-miR-767-3p	CLIP-seq
MIRT756901	hsa-miR-96	CLIP-seq
MIRT2466465	hsa-miR-103b	CLIP-seq
MIRT1555887	hsa-miR-1184	CLIP-seq
MIRT1555888	hsa-miR-1205	CLIP-seq
MIRT1923177	hsa-miR-1208	CLIP-seq
MIRT2466466	hsa-miR-1238	CLIP-seq
MIRT2164684	hsa-miR-1254	CLIP-seq
MIRT2466467	hsa-miR-1257	CLIP-seq
MIRT756818	hsa-miR-1260	CLIP-seq
MIRT756819	hsa-miR-1260b	CLIP-seq
MIRT2466468	hsa-miR-1287	CLIP-seq
MIRT1555889	hsa-miR-1301	CLIP-seq
MIRT756822	hsa-miR-136	CLIP-seq
MIRT2466469	hsa-miR-150	CLIP-seq
MIRT2466470	hsa-miR-186	CLIP-seq
MIRT756826	hsa-miR-188-3p	CLIP-seq
MIRT756827	hsa-miR-18a	CLIP-seq
MIRT756828	hsa-miR-18b	CLIP-seq
MIRT2466471	hsa-miR-199a-3p	CLIP-seq
MIRT2466472	hsa-miR-199b-3p	CLIP-seq
MIRT2466473	hsa-miR-2117	CLIP-seq
MIRT1555890	hsa-miR-22	CLIP-seq
MIRT756834	hsa-miR-28-5p	CLIP-seq
MIRT756835	hsa-miR-300	CLIP-seq
MIRT2164690	hsa-miR-3116	CLIP-seq
MIRT756836	hsa-miR-3121-5p	CLIP-seq
MIRT2466474	hsa-miR-3124-3p	CLIP-seq
MIRT2466475	hsa-miR-3129-5p	CLIP-seq
MIRT2466476	hsa-miR-3133	CLIP-seq
MIRT2466477	hsa-miR-3135b	CLIP-seq
MIRT756837	hsa-miR-3136-3p	CLIP-seq
MIRT756838	hsa-miR-3139	CLIP-seq
MIRT756840	hsa-miR-3144-5p	CLIP-seq
MIRT2466478	hsa-miR-3148	CLIP-seq
MIRT756841	hsa-miR-3150a-5p	CLIP-seq
MIRT756842	hsa-miR-3150b-5p	CLIP-seq
MIRT756843	hsa-miR-3152-5p	CLIP-seq
MIRT756844	hsa-miR-3156-3p	CLIP-seq
MIRT1555891	hsa-miR-3158-5p	CLIP-seq
MIRT756845	hsa-miR-3161	CLIP-seq
MIRT2466479	hsa-miR-3202	CLIP-seq
MIRT2466480	hsa-miR-323b-5p	CLIP-seq
MIRT2466481	hsa-miR-338-5p	CLIP-seq
MIRT1923185	hsa-miR-34c-3p	CLIP-seq
MIRT2466482	hsa-miR-3613-3p	CLIP-seq
MIRT2466483	hsa-miR-361-3p	CLIP-seq
MIRT1923186	hsa-miR-3653	CLIP-seq
MIRT1923187	hsa-miR-3658	CLIP-seq
MIRT756846	hsa-miR-3664-3p	CLIP-seq
MIRT756847	hsa-miR-3672	CLIP-seq
MIRT2164693	hsa-miR-3689d	CLIP-seq
MIRT2466484	hsa-miR-371-5p	CLIP-seq
MIRT2466485	hsa-miR-377	CLIP-seq
MIRT756849	hsa-miR-381	CLIP-seq
MIRT2466486	hsa-miR-384	CLIP-seq
MIRT756850	hsa-miR-3907	CLIP-seq
MIRT2466487	hsa-miR-3915	CLIP-seq
MIRT2466488	hsa-miR-3921	CLIP-seq
MIRT2466489	hsa-miR-3928	CLIP-seq
MIRT756852	hsa-miR-3936	CLIP-seq
MIRT2466490	hsa-miR-3944-5p	CLIP-seq
MIRT2466491	hsa-miR-4251	CLIP-seq
MIRT2164695	hsa-miR-4254	CLIP-seq
MIRT756856	hsa-miR-4269	CLIP-seq
MIRT756857	hsa-miR-4279	CLIP-seq
MIRT756858	hsa-miR-4282	CLIP-seq
MIRT756861	hsa-miR-4301	CLIP-seq
MIRT756863	hsa-miR-4329	CLIP-seq
MIRT2466492	hsa-miR-4422	CLIP-seq
MIRT2466493	hsa-miR-4434	CLIP-seq
MIRT2466494	hsa-miR-4436b-3p	CLIP-seq
MIRT2466495	hsa-miR-4438	CLIP-seq
MIRT2164698	hsa-miR-4448	CLIP-seq
MIRT756868	hsa-miR-4514	CLIP-seq
MIRT2466496	hsa-miR-4516	CLIP-seq
MIRT2466497	hsa-miR-4531	CLIP-seq
MIRT2466498	hsa-miR-4533	CLIP-seq
MIRT1923194	hsa-miR-4540	CLIP-seq
MIRT756870	hsa-miR-4633-3p	CLIP-seq
MIRT2466499	hsa-miR-4639-3p	CLIP-seq
MIRT2466500	hsa-miR-4653-5p	CLIP-seq
MIRT756872	hsa-miR-4659a-3p	CLIP-seq
MIRT756873	hsa-miR-4659b-3p	CLIP-seq
MIRT1555892	hsa-miR-4660	CLIP-seq
MIRT1923195	hsa-miR-4662a-3p	CLIP-seq
MIRT756874	hsa-miR-4665-3p	CLIP-seq
MIRT2466501	hsa-miR-4691-5p	CLIP-seq
MIRT756876	hsa-miR-4692	CLIP-seq
MIRT2466502	hsa-miR-4729	CLIP-seq
MIRT756877	hsa-miR-4735-3p	CLIP-seq
MIRT1923199	hsa-miR-4742-3p	CLIP-seq
MIRT756879	hsa-miR-4742-5p	CLIP-seq
MIRT756881	hsa-miR-4758-3p	CLIP-seq
MIRT756882	hsa-miR-4760-3p	CLIP-seq
MIRT756883	hsa-miR-4761-5p	CLIP-seq
MIRT2466503	hsa-miR-4768-5p	CLIP-seq
MIRT2466504	hsa-miR-4773	CLIP-seq
MIRT756884	hsa-miR-4774-3p	CLIP-seq
MIRT2466505	hsa-miR-4790-3p	CLIP-seq
MIRT2466506	hsa-miR-4797-3p	CLIP-seq
MIRT2466507	hsa-miR-4803	CLIP-seq
MIRT756885	hsa-miR-500a	CLIP-seq
MIRT756886	hsa-miR-501-5p	CLIP-seq
MIRT1555893	hsa-miR-5047	CLIP-seq
MIRT2466508	hsa-miR-5095	CLIP-seq
MIRT2466509	hsa-miR-511	CLIP-seq
MIRT1555894	hsa-miR-544	CLIP-seq
MIRT756888	hsa-miR-548ae	CLIP-seq
MIRT756889	hsa-miR-548aj	CLIP-seq
MIRT756890	hsa-miR-548am	CLIP-seq
MIRT2466510	hsa-miR-548l	CLIP-seq
MIRT2466511	hsa-miR-548n	CLIP-seq
MIRT756891	hsa-miR-548x	CLIP-seq
MIRT2466512	hsa-miR-556-3p	CLIP-seq
MIRT2466513	hsa-miR-563	CLIP-seq
MIRT2466514	hsa-miR-582-5p	CLIP-seq
MIRT2466515	hsa-miR-595	CLIP-seq
MIRT2466516	hsa-miR-600	CLIP-seq
MIRT756893	hsa-miR-624	CLIP-seq
MIRT1923204	hsa-miR-630	CLIP-seq
MIRT2466517	hsa-miR-642b	CLIP-seq
MIRT756895	hsa-miR-7	CLIP-seq
MIRT756896	hsa-miR-708	CLIP-seq
MIRT756898	hsa-miR-873	CLIP-seq
MIRT756899	hsa-miR-875-3p	CLIP-seq
MIRT2466518	hsa-miR-888	CLIP-seq
MIRT756900	hsa-miR-936	CLIP-seq
MIRT2466465	hsa-miR-103b	CLIP-seq
MIRT1555887	hsa-miR-1184	CLIP-seq
MIRT1555888	hsa-miR-1205	CLIP-seq
MIRT1923177	hsa-miR-1208	CLIP-seq
MIRT2466466	hsa-miR-1238	CLIP-seq
MIRT2164684	hsa-miR-1254	CLIP-seq
MIRT2466467	hsa-miR-1257	CLIP-seq
MIRT756818	hsa-miR-1260	CLIP-seq
MIRT756819	hsa-miR-1260b	CLIP-seq
MIRT2466468	hsa-miR-1287	CLIP-seq
MIRT1555889	hsa-miR-1301	CLIP-seq
MIRT756822	hsa-miR-136	CLIP-seq
MIRT2466469	hsa-miR-150	CLIP-seq
MIRT2466470	hsa-miR-186	CLIP-seq
MIRT756826	hsa-miR-188-3p	CLIP-seq
MIRT2466471	hsa-miR-199a-3p	CLIP-seq
MIRT2466472	hsa-miR-199b-3p	CLIP-seq
MIRT2466473	hsa-miR-2117	CLIP-seq
MIRT1555890	hsa-miR-22	CLIP-seq
MIRT756835	hsa-miR-300	CLIP-seq
MIRT2164690	hsa-miR-3116	CLIP-seq
MIRT756836	hsa-miR-3121-5p	CLIP-seq
MIRT2466474	hsa-miR-3124-3p	CLIP-seq
MIRT2466475	hsa-miR-3129-5p	CLIP-seq
MIRT2466476	hsa-miR-3133	CLIP-seq
MIRT2466477	hsa-miR-3135b	CLIP-seq
MIRT756837	hsa-miR-3136-3p	CLIP-seq
MIRT756840	hsa-miR-3144-5p	CLIP-seq
MIRT2466478	hsa-miR-3148	CLIP-seq
MIRT756841	hsa-miR-3150a-5p	CLIP-seq
MIRT756842	hsa-miR-3150b-5p	CLIP-seq
MIRT756843	hsa-miR-3152-5p	CLIP-seq
MIRT756844	hsa-miR-3156-3p	CLIP-seq
MIRT1555891	hsa-miR-3158-5p	CLIP-seq
MIRT2466480	hsa-miR-323b-5p	CLIP-seq
MIRT2466481	hsa-miR-338-5p	CLIP-seq
MIRT1923185	hsa-miR-34c-3p	CLIP-seq
MIRT2466482	hsa-miR-3613-3p	CLIP-seq
MIRT2466483	hsa-miR-361-3p	CLIP-seq
MIRT1923186	hsa-miR-3653	CLIP-seq
MIRT1923187	hsa-miR-3658	CLIP-seq
MIRT756847	hsa-miR-3672	CLIP-seq
MIRT2164693	hsa-miR-3689d	CLIP-seq
MIRT2466485	hsa-miR-377	CLIP-seq
MIRT756849	hsa-miR-381	CLIP-seq
MIRT2466486	hsa-miR-384	CLIP-seq
MIRT2466487	hsa-miR-3915	CLIP-seq
MIRT2466488	hsa-miR-3921	CLIP-seq
MIRT2466489	hsa-miR-3928	CLIP-seq
MIRT756852	hsa-miR-3936	CLIP-seq
MIRT2466490	hsa-miR-3944-5p	CLIP-seq
MIRT2466491	hsa-miR-4251	CLIP-seq
MIRT2164695	hsa-miR-4254	CLIP-seq
MIRT756856	hsa-miR-4269	CLIP-seq
MIRT756857	hsa-miR-4279	CLIP-seq
MIRT756858	hsa-miR-4282	CLIP-seq
MIRT756861	hsa-miR-4301	CLIP-seq
MIRT756863	hsa-miR-4329	CLIP-seq
MIRT2466492	hsa-miR-4422	CLIP-seq
MIRT2466493	hsa-miR-4434	CLIP-seq
MIRT2164698	hsa-miR-4448	CLIP-seq
MIRT756868	hsa-miR-4514	CLIP-seq
MIRT2466496	hsa-miR-4516	CLIP-seq
MIRT2466497	hsa-miR-4531	CLIP-seq
MIRT1923194	hsa-miR-4540	CLIP-seq
MIRT2466499	hsa-miR-4639-3p	CLIP-seq
MIRT2466500	hsa-miR-4653-5p	CLIP-seq
MIRT756872	hsa-miR-4659a-3p	CLIP-seq
MIRT756873	hsa-miR-4659b-3p	CLIP-seq
MIRT1555892	hsa-miR-4660	CLIP-seq
MIRT1923195	hsa-miR-4662a-3p	CLIP-seq
MIRT756874	hsa-miR-4665-3p	CLIP-seq
MIRT2466501	hsa-miR-4691-5p	CLIP-seq
MIRT756876	hsa-miR-4692	CLIP-seq
MIRT2466502	hsa-miR-4729	CLIP-seq
MIRT1923199	hsa-miR-4742-3p	CLIP-seq
MIRT756879	hsa-miR-4742-5p	CLIP-seq
MIRT756881	hsa-miR-4758-3p	CLIP-seq
MIRT2466503	hsa-miR-4768-5p	CLIP-seq
MIRT2466504	hsa-miR-4773	CLIP-seq
MIRT756884	hsa-miR-4774-3p	CLIP-seq
MIRT2466505	hsa-miR-4790-3p	CLIP-seq
MIRT2466506	hsa-miR-4797-3p	CLIP-seq
MIRT2466507	hsa-miR-4803	CLIP-seq
MIRT756885	hsa-miR-500a	CLIP-seq
MIRT756886	hsa-miR-501-5p	CLIP-seq
MIRT1555893	hsa-miR-5047	CLIP-seq
MIRT2466509	hsa-miR-511	CLIP-seq
MIRT1555894	hsa-miR-544	CLIP-seq
MIRT756888	hsa-miR-548ae	CLIP-seq
MIRT756889	hsa-miR-548aj	CLIP-seq
MIRT756890	hsa-miR-548am	CLIP-seq
MIRT2466510	hsa-miR-548l	CLIP-seq
MIRT2466511	hsa-miR-548n	CLIP-seq
MIRT756891	hsa-miR-548x	CLIP-seq
MIRT2466513	hsa-miR-563	CLIP-seq
MIRT2466515	hsa-miR-595	CLIP-seq
MIRT2466516	hsa-miR-600	CLIP-seq
MIRT756893	hsa-miR-624	CLIP-seq
MIRT1923204	hsa-miR-630	CLIP-seq
MIRT2466517	hsa-miR-642b	CLIP-seq
MIRT756899	hsa-miR-875-3p	CLIP-seq
MIRT756900	hsa-miR-936	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 28514442, 29892012, 32296183, 33961781, 35271311
GO:0005737	Component	Cytoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	IEA
GO:0015031	Process	Protein transport	IEA
GO:0016607	Component	Nuclear speck	IDA

Other IDs

• MIM: 614888
• HGNC: 25662
• e!Ensembl: ENSG00000103591

Protein

• UniProt ID: Q6PD74
• Protein name: Alpha- and gamma-adaptin-binding protein p34
• Protein function: May be involved in endocytic recycling of growth factor receptors such as EGFR.
• PDB: 7TWD
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF10199	Adaptin_binding	155 → 294		Family

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed, including in skin and keratinocytes, with highest levels in adrenal gland, rectum and thymus. {ECO:0000269|PubMed:23000146, ECO:0000269|PubMed:23064416}.
• Sequence:

  MAAGVPCALVTSCSSVFSGDQLVQHILGTEDLIVEVTSNDAVRFYPWTIDNKYYSADINL
  CVVPNKFLVTAEIAESVQAFVVYFDSTQKSGLDSVSSWLPLAKAWLPEVMILVCDRVSED
  GINRQKAQEWCIKHGFELVELSPEELPEEDDDFPESTGVKRIVQALNANVWSNVVMKNDR
  NQGFSLLNSLTGTNHSIGSADPCHPEQPHLPAADSTESLSDHRGGASNTTDAQVDSIVDP
  MLDLDIQELASLTTGGGDVENFERLFSKLKEMKDKAATLPHEQRKVHAEKVAKAFWMAIG
  GDRDEIEGLSSDEEH

• Sequence length: 315

Associated diseases

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
AAGAB-related disorder	Likely pathogenic	rs2505534485	RCV003391336
Colon adenocarcinoma	Pathogenic	rs748785284	RCV005870015
Palmoplantar keratoderma	Likely pathogenic	rs1057518846	RCV000415378
Palmoplantar keratoderma, punctate type 1A	Likely pathogenic; Pathogenic	rs753247583, rs748785284, rs2505364268, rs2505534817, rs746488412, rs200564757, rs1567027297, rs781596375, rs1567027610, rs1567037561	RCV001329993 RCV005010972 RCV003130947 RCV004594755 RCV000032947 RCV000032948 RCV000032949 RCV000032950 RCV000032951 RCV001784368

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Cervical cancer	Benign	rs117853536	RCV005905175
Gastric cancer	Benign	rs117853536	RCV005905176
Hepatocellular carcinoma	Benign	rs117853536	RCV005905173
Malignant tumor of esophagus	Benign	rs117853536	RCV005905174
Thyroid cancer, nonmedullary, 1	-; Uncertain significance	rs1266071749, rs753247583	RCV006097537 RCV005888873

Associations from Text Mining
Disease Name	Relationship Type	References
Breast Neoplasms	Associate	31200764
Keratoderma Palmoplantar	Associate	23064416, 31353312
Keratosis palmoplantaris papulosa	Associate	23000146, 26608363, 31353312, 33765759
Skin Diseases	Associate	31353312