QTMAN (queuosine-tRNA mannosyltransferase)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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79712 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Queuosine-tRNA mannosyltransferase |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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QTMAN |
Synonyms (NCBI Gene)
Gene synonyms aliases
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GTDC1, Hmat-Xa, mat-Xa |
Chromosome
Chromosome number
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2 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2q22.3 |
miRNA
miRNA information provided by mirtarbase database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | Q4AE62 | |||||||||||||||
Protein name | tRNA-queuosine alpha-mannosyltransferase (QTMAN) (EC 2.4.1.110) (Glycosyltransferase-like domain-containing protein 1) (Mannosyltransferase-like protein Xa) (Mat-Xa) | |||||||||||||||
Protein function | Glycosyltransferase that specifically catalyzes mannosylation of cytoplasmic tRNA(Asp) modified with queuosine at position 34 (queuosine(34)) (PubMed:37992713). Mannosylates the cyclopentene moiety of queuosine(34) in tRNA(Asp) to form mannosyl- | |||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. Expressed at high levels in the lung, brain, spleen, testis, placenta. ovary, pancreas, spleen and peripheral blood leukocytes. Expressed at low level in the colon, small intestine, kidney, skeletal muscle and thymus. Expre | |||||||||||||||
Sequence |
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Sequence length | 458 | |||||||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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