ATP13A3 (ATPase 13A3)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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79572 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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ATPase 13A3 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ATP13A3 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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AFURS1, PPH5 |
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Chromosome
Chromosome number
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3 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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3q29 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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ATP13A3 is a member of the P-type ATPase family of proteins that transport a variety of cations across membranes. Other P-type ATPases include ATP7B (MIM 606882) and ATP7A (MIM 300011).[supplied by OMIM, Aug 2008] |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||||||||||||
| UniProt ID | Q9H7F0 | ||||||||||||||||||||||||||||||
| Protein name | Polyamine-transporting ATPase 13A3 (ATPase family homolog up-regulated in senescence cells 1) (Putrescine transporting ATPase) (EC 7.6.2.16) | ||||||||||||||||||||||||||||||
| Protein function | ATP-driven pump involved in endocytosis-dependent polyamine transport. Uses ATP as an energy source to transfer polyamine precursor putrescine from the endosomal compartment to the cytosol. {ECO:0000269|PubMed:27429841, ECO:0000269|PubMed:333107 | ||||||||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Broadly expressed. {ECO:0000269|PubMed:29505581}. | ||||||||||||||||||||||||||||||
| Sequence | |||||||||||||||||||||||||||||||
| Sequence length | 1226 | ||||||||||||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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