Gene Gene information from NCBI Gene database.
Entrez ID 79465
Gene name UL16 binding protein 3
Gene symbol ULBP3
Synonyms (NCBI Gene)
N2DL-3NKG2DL3RAET1N
Chromosome 6
Chromosome location 6q25.1
Summary The protein encoded by this gene is one of several related ligands of the KLRK1/NKG2D receptor, which is found in primary NK cells. Binding of these ligands to the receptor activates several signal transduction pathways, including the JAK2, STAT5, and ERK
miRNA miRNA information provided by mirtarbase database.
526
miRTarBase ID miRNA Experiments Reference
MIRT670374 hsa-miR-514a-5p HITS-CLIP 23313552
MIRT670373 hsa-miR-383-3p HITS-CLIP 23313552
MIRT629520 hsa-miR-6499-5p HITS-CLIP 23313552
MIRT670372 hsa-miR-326 HITS-CLIP 23313552
MIRT670371 hsa-miR-330-5p HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
16
GO ID Ontology Definition Evidence Reference
GO:0001916 Process Positive regulation of T cell mediated cytotoxicity IBA
GO:0002376 Process Immune system process IEA
GO:0002476 Process Antigen processing and presentation of endogenous peptide antigen via MHC class Ib IBA
GO:0002486 Process Antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent IBA
GO:0005515 Function Protein binding IPI 11754823, 18544572, 28559451, 32814053
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
605699 14895 ENSG00000131019
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9BZM4
Protein name UL16-binding protein 3 (ALCAN-gamma) (NKG2D ligand 3) (N2DL-3) (NKG2DL3) (Retinoic acid early transcript 1N)
Protein function Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
PDB 1KCG
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00129 MHC_I 30 206 Class I Histocompatibility antigen, domains alpha 1 and 2 Domain
Sequence
Sequence length 244
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Natural killer cell mediated cytotoxicity   Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell